Class information for:
Level 1: BILE ACID SEQUESTRANT//COLESEVELAM HCL//COLESEVELAM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23438 346 32.6 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
171 3       MONASCUS//CITRININ//MONASCUS PURPUREUS 58457
419 2             STATINS//EZETIMIBE//SIMVASTATIN 16502
23438 1                   BILE ACID SEQUESTRANT//COLESEVELAM HCL//COLESEVELAM 346

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BILE ACID SEQUESTRANT authKW 2240016 16% 45% 57
2 COLESEVELAM HCL authKW 1441437 6% 78% 21
3 COLESEVELAM authKW 1427278 8% 56% 29
4 COLESEVELAM HYDROCHLORIDE authKW 441259 1% 100% 5
5 POLYCATIONIC SALTS authKW 353007 1% 100% 4
6 COLESTIPOL authKW 275773 3% 31% 10
7 COLESTIMIDE authKW 180171 2% 29% 7
8 2 IONENE OLIGOMERS authKW 176504 1% 100% 2
9 ENDOTHERMIC BINDING authKW 176504 1% 100% 2
10 NON ABSORBED authKW 176504 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 1093 34% 0% 117
2 Medicine, General & Internal 156 11% 0% 39
3 Endocrinology & Metabolism 154 9% 0% 32
4 Chemistry, Medicinal 154 7% 0% 24
5 Cardiac & Cardiovascular System 146 9% 0% 32
6 Polymer Science 129 8% 0% 29
7 Peripheral Vascular Diseases 70 5% 0% 17
8 Chemistry, Multidisciplinary 62 12% 0% 40
9 Engineering, Chemical 61 7% 0% 24
10 Medicine, Research & Experimental 9 3% 0% 11

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARDIOL HEPATOL GERIATR MED INTEGRATED MED 88252 0% 100% 1
2 CHIEF SECT ENDOCRINOL 88252 0% 100% 1
3 CLIN CHEM G03550 88252 0% 100% 1
4 MED 0813 88252 0% 100% 1
5 METRO TECH 88252 0% 100% 1
6 MICROBIAL PATHOGENIC GRP MED MICROBIOL 88252 0% 100% 1
7 SANKYO CLIN PHARMACOL UNIT 88252 0% 100% 1
8 VENTU BUSINESS DEV ORG 88252 0% 100% 1
9 CHEM 801 SHERBROOKE ST W 70599 1% 40% 2
10 ENDOCARE 70599 1% 40% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF NIPPON MEDICAL SCHOOL 6312 1% 1% 5
2 CHEMICAL ENGINEERING 4224 2% 1% 8
3 JOURNAL OF CLINICAL LIPIDOLOGY 3384 1% 1% 5
4 JOURNAL OF MACROMOLECULAR SCIENCE-PURE AND APPLIED CHEMISTRY 3290 3% 0% 9
5 ENDOCRINE PRACTICE 2882 2% 1% 6
6 CHEMICAL ENGINEERING PROGRESS 2819 2% 0% 8
7 ARTERY 2656 1% 1% 4
8 METABOLIC SYNDROME AND RELATED DISORDERS 2318 1% 1% 4
9 AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS 1881 1% 1% 3
10 JOURNAL OF PHARMACOBIO-DYNAMICS 1346 1% 0% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BILE ACID SEQUESTRANT 2240016 16% 45% 57 Search BILE+ACID+SEQUESTRANT Search BILE+ACID+SEQUESTRANT
2 COLESEVELAM HCL 1441437 6% 78% 21 Search COLESEVELAM+HCL Search COLESEVELAM+HCL
3 COLESEVELAM 1427278 8% 56% 29 Search COLESEVELAM Search COLESEVELAM
4 COLESEVELAM HYDROCHLORIDE 441259 1% 100% 5 Search COLESEVELAM+HYDROCHLORIDE Search COLESEVELAM+HYDROCHLORIDE
5 POLYCATIONIC SALTS 353007 1% 100% 4 Search POLYCATIONIC+SALTS Search POLYCATIONIC+SALTS
6 COLESTIPOL 275773 3% 31% 10 Search COLESTIPOL Search COLESTIPOL
7 COLESTIMIDE 180171 2% 29% 7 Search COLESTIMIDE Search COLESTIMIDE
8 2 IONENE OLIGOMERS 176504 1% 100% 2 Search 2+IONENE+OLIGOMERS Search 2+IONENE+OLIGOMERS
9 ENDOTHERMIC BINDING 176504 1% 100% 2 Search ENDOTHERMIC+BINDING Search ENDOTHERMIC+BINDING
10 NON ABSORBED 176504 1% 100% 2 Search NON+ABSORBED Search NON+ABSORBED

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 YOUNK, LM , DAVIS, SN , (2012) EVALUATION OF COLESEVELAM HYDROCHLORIDE FOR THE TREATMENT OF TYPE 2 DIABETES.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 8. ISSUE 4. P. 515 -525 32 56% 8
2 TZIOMALOS, K , KARAGIANNIS, A , MIKHAILIDIS, DP , ATHYROS, VG , (2013) COLESEVELAM: A NEW AND IMPROVED BILE ACID SEQUESTRANT?.CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 17. P. 3115-3123 40 43% 5
3 BRUNETTI, L , HERMES-DESANTIS, ER , (2010) THE ROLE OF COLESEVELAM HYDROCHLORIDE IN HYPERCHOLESTEROLEMIA AND TYPE 2 DIABETES MELLITUS.ANNALS OF PHARMACOTHERAPY. VOL. 44. ISSUE 7-8. P. 1196-1206 27 50% 6
4 HANUS, M , ZHOROV, E , (2006) BILE ACID SALT BINDING WITH COLESEVELAM HCL IS NOT AFFECTED BY SUSPENSION IN COMMON BEVERAGES.JOURNAL OF PHARMACEUTICAL SCIENCES. VOL. 95. ISSUE 12. P. 2751-2759 16 89% 12
5 CORSINI, A , WINDLER, E , FARNIER, M , (2009) COLESEVELAM HYDROCHLORIDE: USEFULNESS OF A SPECIFICALLY ENGINEERED BILE ACID SEQUESTRANT FOR LOWERING LDL-CHOLESTEROL.EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION. VOL. 16. ISSUE 1. P. 1 -9 23 53% 14
6 BYKADI, S , SAYEED, VA , KHAN, MA , KRISHNAIAH, YSR , YANG, YS , (2014) COMPARATIVE EVALUATION OF IN VITRO EFFICACY OF COLESEVELAM HYDROCHLORIDE TABLETS.DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. VOL. 40. ISSUE 9. P. 1173 -1179 14 74% 0
7 OUT, C , GROEN, AK , BRUFAU, G , (2012) BILE ACID SEQUESTRANTS: MORE THAN SIMPLE RESINS.CURRENT OPINION IN LIPIDOLOGY. VOL. 23. ISSUE 1. P. 43 -55 30 30% 30
8 BROWN, KS , ARMSTRONG, IC , WANG, A , WALKER, JR , NOVECK, RJ , SWEARINGEN, D , ALLISON, M , KISSLING, JC , KISICKI, J , SALAZAR, DE , (2010) EFFECT OF THE BILE ACID SEQUESTRANT COLESEVELAM ON THE PHARMACOKINETICS OF PIOGLITAZONE, REPAGLINIDE, ESTROGEN ESTRADIOL, NORETHINDRONE, LEVOTHYROXINE, AND GLYBURIDE.JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 50. ISSUE 5. P. 554-565 17 61% 12
9 MAZIDI, M , REZAIE, P , KARIMI, E , KENGNE, AP , (2017) THE EFFECTS OF BILE ACID SEQUESTRANTS ON LIPID PROFILE AND BLOOD GLUCOSE CONCENTRATIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS.INTERNATIONAL JOURNAL OF CARDIOLOGY. VOL. 227. ISSUE . P. 850 -857 19 46% 0
10 SONNETT, TE , LEVIEN, TL , NEUMILLER, JJ , GATES, BJ , SETTER, SM , (2009) COLESEVELAM HYDROCHLORIDE FOR THE TREATMENT OF TYPE 2 DIABETES MELLITUS.CLINICAL THERAPEUTICS. VOL. 31. ISSUE 2. P. 245-259 20 51% 9

Classes with closest relation at Level 1


Rank Class id link
1 5462 FARNESOID X RECEPTOR//FXR//TGR5
2 13608 EZETIMIBE//NPC1L1//CHOLESTEROL ABSORPTION INHIBITOR
3 9257 PRAVASTATIN//HMG COA REDUCTASE INHIBITORS//MEVALONIC ACID
4 35836 FILIPPO PACINI//4 TETRAHYDRONAPHTHALENE//ACAROPATHOGEN
5 16617 BILE ACID MALABSORPTION//SEHCAT//ASBT
6 413 STATINS//LOW DENSITY LIPOPROTEIN CHOLESTEROL//ATORVASTATIN
7 37724 CHROMONE ALKALOIDS//ROHITUKINE//DYSOXYLUM BINECTARIFERUM
8 12751 NIACIN//LAROPIPRANT//GPR109A
9 18626 PITAVASTATIN//NK 104//CAS 147526 32 7
10 36893 AMMI VISNAGA//VISNAGIN//FURANOCHROMONES

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