Class information for:
Level 1: EZETIMIBE//NPC1L1//CHOLESTEROL ABSORPTION INHIBITOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13608 825 39.5 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
171 3       MONASCUS//CITRININ//MONASCUS PURPUREUS 58457
419 2             STATINS//EZETIMIBE//SIMVASTATIN 16502
13608 1                   EZETIMIBE//NPC1L1//CHOLESTEROL ABSORPTION INHIBITOR 825

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EZETIMIBE authKW 5779091 42% 45% 349
2 NPC1L1 authKW 750389 5% 48% 42
3 CHOLESTEROL ABSORPTION INHIBITOR authKW 644795 3% 62% 28
4 NIEMANN PICK C1 LIKE 1 authKW 448604 2% 61% 20
5 CHOLESTEROL ABSORPTION authKW 321194 6% 17% 50
6 EZETIMIBE SIMVASTATIN authKW 197387 1% 67% 8
7 EZETIMIBE SIMVASTATIN COMBINATION authKW 185056 1% 100% 5
8 CHOLESTEROL ABSORPTION INHIBITION authKW 182202 1% 62% 8
9 EARLY CLIN EXPT MED address 139497 1% 54% 7
10 INTESTINAL CHOLESTEROL ABSORPTION authKW 119377 1% 32% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cardiac & Cardiovascular System 2515 22% 0% 185
2 Pharmacology & Pharmacy 1183 24% 0% 196
3 Peripheral Vascular Diseases 1043 11% 0% 91
4 Medicine, General & Internal 746 15% 0% 125
5 Endocrinology & Metabolism 309 9% 0% 71
6 Medicine, Research & Experimental 182 7% 0% 55
7 Biochemistry & Molecular Biology 176 16% 0% 135
8 Nutrition & Dietetics 156 4% 0% 35
9 Gastroenterology & Hepatology 123 4% 0% 37
10 Transplantation 45 2% 0% 16

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EARLY CLIN EXPT MED 139497 1% 54% 7
2 RECH CLIN POLYCLIN 74022 0% 100% 2
3 SECT LIPID SCI 67144 2% 13% 14
4 FEDERAT PUBL SERV PERSONNEL MUTUAL ASSOC 41634 0% 38% 3
5 AFFILIATED BOAI HOSP 37011 0% 100% 1
6 AREA PREVENC REHABIL CARDIACA 37011 0% 100% 1
7 ARTEROSCLEROSIS 37011 0% 100% 1
8 ASKLEPIOS HOSP ST GEORG 37011 0% 100% 1
9 ATLANTA VA MED 119 37011 0% 100% 1
10 ATLANTIC MULTIORGAN TRANSPLANTAT PROGRAM 37011 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CLINICAL LIPIDOLOGY 18414 2% 3% 18
2 LIPIDS IN HEALTH AND DISEASE 9778 2% 1% 20
3 CURRENT MEDICAL RESEARCH AND OPINION 8474 4% 1% 32
4 JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS 6478 2% 1% 14
5 INTERNATIONAL JOURNAL OF CLINICAL PRACTICE 4288 3% 1% 22
6 JOURNAL OF LIPID RESEARCH 4139 4% 0% 31
7 ATHEROSCLEROSIS SUPPLEMENTS 3331 1% 2% 5
8 ATHEROSCLEROSIS 2696 3% 0% 28
9 CURRENT OPINION IN LIPIDOLOGY 2246 1% 1% 9
10 AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS 2188 1% 1% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EZETIMIBE 5779091 42% 45% 349 Search EZETIMIBE Search EZETIMIBE
2 NPC1L1 750389 5% 48% 42 Search NPC1L1 Search NPC1L1
3 CHOLESTEROL ABSORPTION INHIBITOR 644795 3% 62% 28 Search CHOLESTEROL+ABSORPTION+INHIBITOR Search CHOLESTEROL+ABSORPTION+INHIBITOR
4 NIEMANN PICK C1 LIKE 1 448604 2% 61% 20 Search NIEMANN+PICK+C1+LIKE+1 Search NIEMANN+PICK+C1+LIKE+1
5 CHOLESTEROL ABSORPTION 321194 6% 17% 50 Search CHOLESTEROL+ABSORPTION Search CHOLESTEROL+ABSORPTION
6 EZETIMIBE SIMVASTATIN 197387 1% 67% 8 Search EZETIMIBE+SIMVASTATIN Search EZETIMIBE+SIMVASTATIN
7 EZETIMIBE SIMVASTATIN COMBINATION 185056 1% 100% 5 Search EZETIMIBE+SIMVASTATIN+COMBINATION Search EZETIMIBE+SIMVASTATIN+COMBINATION
8 CHOLESTEROL ABSORPTION INHIBITION 182202 1% 62% 8 Search CHOLESTEROL+ABSORPTION+INHIBITION Search CHOLESTEROL+ABSORPTION+INHIBITION
9 INTESTINAL CHOLESTEROL ABSORPTION 119377 1% 32% 10 Search INTESTINAL+CHOLESTEROL+ABSORPTION Search INTESTINAL+CHOLESTEROL+ABSORPTION
10 NIEMANN PICK TYPE C1 LIKE 1 111033 0% 100% 3 Search NIEMANN+PICK+TYPE+C1+LIKE+1 Search NIEMANN+PICK+TYPE+C1+LIKE+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DAVIS, HR , TERSHAKOVEC, AM , TOMASSINI, JE , MUSLINER, T , (2011) INTESTINAL STEROL TRANSPORTERS AND CHOLESTEROL ABSORPTION INHIBITION.CURRENT OPINION IN LIPIDOLOGY. VOL. 22. ISSUE 6. P. 467 -478 73 82% 9
2 PIRILLO, A , CATAPANO, AL , NORATA, GD , (2016) NIEMANN-PICK C1-LIKE 1 (NPC1L1) INHIBITION AND CARDIOVASCULAR DISEASES.CURRENT MEDICINAL CHEMISTRY. VOL. 23. ISSUE 10. P. 983 -999 70 63% 1
3 TOTH, PP , CATAPANO, A , TOMASSINI, JE , TERSHAKOVEC, AM , (2010) UPDATE ON THE EFFICACY AND SAFETY OF COMBINATION EZETIMIBE PLUS STATIN THERAPY.CLINICAL LIPIDOLOGY. VOL. 5. ISSUE 5. P. 655 -684 88 59% 4
4 GAZI, IF , MIKHAILIDIS, DP , (2006) NON-LOW-DENSITY LIPOPROTEIN CHOLESTEROL-ASSOCIATED ACTIONS OF EZETIMIBE: AN OVERVIEW.EXPERT OPINION ON THERAPEUTIC TARGETS. VOL. 10. ISSUE 6. P. 851-866 83 62% 22
5 LIOUDAKI, E , GANOTAKIS, ES , MIKHAILIDIS, DP , (2011) EZETIMIBE; MORE THAN A LOW DENSITY LIPOPROTEIN CHOLESTEROL LOWERING DRUG? AN UPDATE AFTER 4 YEARS.CURRENT VASCULAR PHARMACOLOGY. VOL. 9. ISSUE 1. P. 62 -86 95 45% 23
6 KATSIKI, N , THEOCHARIDOU, E , KARAGIANNIS, A , ATHYROS, VG , MIKHAILIDIS, DP , (2013) EZETIMIBE THERAPY FOR DYSLIPIDEMIA: AN UPDATE.CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 17. P. 3107-3114 74 55% 14
7 JIA, L , BETTERS, JL , YU, LQ , (2011) NIEMANN-PICK C1-LIKE 1 (NPC1L1) PROTEIN IN INTESTINAL AND HEPATIC CHOLESTEROL TRANSPORT.ANNUAL REVIEW OF PHYSIOLOGY, VOL 73. VOL. 73. ISSUE . P. 239 -259 66 50% 66
8 BETTERS, JL , YU, LQ , (2010) NPC1L1 AND CHOLESTEROL TRANSPORT.FEBS LETTERS. VOL. 584. ISSUE 13. P. 2740 -2747 55 64% 42
9 DAVIS, HR , VELTRI, ER , (2007) ZETIA: INHIBITION OF NIEMANN-PICK C1 LIKE 1 (NPC1L1) TO REDUCE INTESTINAL CHOLESTEROL ABSORPTION AND TREAT HYPERLIPIDEMIA.JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. VOL. 14. ISSUE 3. P. 99 -108 38 90% 95
10 KALOGIROU, M , TSIMIHODIMOS, V , ELISAF, M , (2010) PLEIOTROPIC EFFECTS OF EZETIMIBE: DO THEY REALLY EXIST?.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 633. ISSUE 1-3. P. 62-70 59 60% 25

Classes with closest relation at Level 1


Rank Class id link
1 3547 PLANT STEROLS//PHYTOSTEROLS//SITOSTEROL
2 413 STATINS//LOW DENSITY LIPOPROTEIN CHOLESTEROL//ATORVASTATIN
3 23438 BILE ACID SEQUESTRANT//COLESEVELAM HCL//COLESEVELAM
4 18946 ATORVASTATIN CALCIUM//EZETIMIBE//ROSUVASTATIN CALCIUM
5 9366 PCSK9//PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9//ALIROCUMAB
6 18626 PITAVASTATIN//NK 104//CAS 147526 32 7
7 12751 NIACIN//LAROPIPRANT//GPR109A
8 7494 STATINS//RHABDOMYOLYSIS//STATIN INTOLERANCE
9 10374 FENOFIBRATE//FENOFIBRIC ACID//FIBRATES
10 4983 CHYLOMICRON REMNANTS//POSTPRANDIAL LIPEMIA//APOLIPOPROTEIN B 48

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