Class information for:
Level 2: NA K ATPASE//OUABAIN//DIGOXIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1104 9793 34.0 59%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
553 3       BRASSINOSTEROIDS//NA K ATPASE//OUABAIN 17999
1104 2             NA K ATPASE//OUABAIN//DIGOXIN 9793
3324 1                   MARINOBUFAGENIN//OUABAIN//DIGITALIS LIKE FACTOR 2009
3645 1                   ATPASE NA K//NA K ATPASE//CURRENT TOPICS IN MEMBRANES AND TRANSPORT 1937
5719 1                   NA K ATPASE//SODIUM PUMP//RECH CARDIOL 1584
5941 1                   DIGOXIN//SERUM DIGOXIN CONCENTRATION//DIGITALIS 1555
14535 1                   CARDIAC GLYCOSIDES//OUABAIN//ANTIARIS TOXICARIA 764
16992 1                   NERIUM OLEANDER//OLEANDER//OLEANDRIN 623
18114 1                   BUFALIN//BUFADIENOLIDES//CHAN SU 565
23436 1                   DIGITALIS LANATA//CARDENOLIDE BIOSYNTHESIS//PROGESTERONE 5 BETA REDUCTASE 346
24173 1                   PHOSPHOLEMMAN//FXYD PROTEINS//FXYD 321
35919 1                   2 1 OXO 2 SUBSTITUTED AMINOPROPYLAMINO 4 5 6 7 TETRAHYDROBENZOBTHIOPHEN 3 CARBOXYLIC ACID ETHYL ESTERS PHARMA//6 NITRO QUINOLINE//ANTIARRHYTHMIC SCREENING 89

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NA K ATPASE authKW 624457 8% 26% 774
2 OUABAIN authKW 611816 5% 38% 513
3 DIGOXIN authKW 512621 4% 39% 417
4 CARDIAC GLYCOSIDES authKW 409361 2% 57% 229
5 BUFALIN authKW 272301 1% 82% 107
6 SODIUM PUMP authKW 261742 2% 41% 204
7 BUFADIENOLIDES authKW 209268 1% 65% 104
8 MARINOBUFAGENIN authKW 193385 1% 97% 64
9 ATPASE NA K authKW 165316 1% 75% 71
10 CARDIOTONIC STEROIDS authKW 154942 1% 84% 59

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 12140 22% 0% 2184
2 Biochemistry & Molecular Biology 9526 29% 0% 2808
3 Physiology 7820 11% 0% 1034
4 Biophysics 5420 9% 0% 928
5 Peripheral Vascular Diseases 3459 6% 0% 609
6 Cardiac & Cardiovascular System 3315 8% 0% 826
7 Cell Biology 2018 9% 0% 911
8 Medical Laboratory Technology 1806 3% 0% 245
9 Chemistry, Medicinal 1031 4% 0% 373
10 Integrative & Complementary Medicine 872 1% 0% 126

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEM ENDOKRINOL 61157 0% 55% 36
2 RECH CARDIOL 23608 0% 63% 12
3 TRANSPORT ATPASE 18697 0% 100% 6
4 HEART HYPERTENS KIDNEY DIS 16024 0% 86% 6
5 PHYSIOL PHARMACOL METAB CARDIOVASC SCI 13537 0% 43% 10
6 JCE MED 12465 0% 100% 4
7 MED SERVRENAL UNIT 12465 0% 100% 4
8 PATHOPHYSIOL ION TRANSPORT DISORDERS 9970 0% 80% 4
9 PHARMACOL TRANSPORTS ION MEMBRANAI 9734 0% 63% 5
10 ROCKLAND 1 9348 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CURRENT TOPICS IN MEMBRANES AND TRANSPORT 68349 1% 23% 94
2 BIOCHIMICA ET BIOPHYSICA ACTA 6771 3% 1% 257
3 THERAPEUTIC DRUG MONITORING 6308 1% 2% 88
4 JOURNAL OF MEMBRANE BIOLOGY 5040 1% 2% 88
5 HYPERTENSION 5011 1% 1% 139
6 JOURNAL OF BIOLOGICAL CHEMISTRY 4094 5% 0% 484
7 JOURNAL OF HYPERTENSION 3374 1% 1% 105
8 CLINICAL AND EXPERIMENTAL HYPERTENSION PART A-THEORY AND PRACTICE 3216 0% 3% 38
9 BIOLOGICHESKIE MEMBRANY 3065 1% 2% 52
10 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 3059 1% 1% 86

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NA K ATPASE 624457 8% 26% 774 Search NA+K+ATPASE Search NA+K+ATPASE
2 OUABAIN 611816 5% 38% 513 Search OUABAIN Search OUABAIN
3 DIGOXIN 512621 4% 39% 417 Search DIGOXIN Search DIGOXIN
4 CARDIAC GLYCOSIDES 409361 2% 57% 229 Search CARDIAC+GLYCOSIDES Search CARDIAC+GLYCOSIDES
5 BUFALIN 272301 1% 82% 107 Search BUFALIN Search BUFALIN
6 SODIUM PUMP 261742 2% 41% 204 Search SODIUM+PUMP Search SODIUM+PUMP
7 BUFADIENOLIDES 209268 1% 65% 104 Search BUFADIENOLIDES Search BUFADIENOLIDES
8 MARINOBUFAGENIN 193385 1% 97% 64 Search MARINOBUFAGENIN Search MARINOBUFAGENIN
9 ATPASE NA K 165316 1% 75% 71 Search ATPASE+NA+K Search ATPASE+NA+K
10 CARDIOTONIC STEROIDS 154942 1% 84% 59 Search CARDIOTONIC+STEROIDS Search CARDIOTONIC+STEROIDS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BAGROV, AY , SHAPIRO, JI , FEDOROVA, OV , (2009) ENDOGENOUS CARDIOTONIC STEROIDS: PHYSIOLOGY, PHARMACOLOGY, AND NOVEL THERAPEUTIC TARGETS.PHARMACOLOGICAL REVIEWS. VOL. 61. ISSUE 1. P. 9 -38 269 80% 159
2 SCHEINER-BOBIS, G , SCHONER, W , (2007) ENDOGENOUS AND EXOGENOUS CARDIAC GLYCOSIDES: THEIR ROLES IN HYPERTENSION, SALT METABOLISM, AND CELL GROWTH.AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. VOL. 293. ISSUE 2. P. C509 -C536 258 73% 210
3 KHUNDMIRI, SJ , (2014) ADVANCES IN UNDERSTANDING THE ROLE OF CARDIAC GLYCOSIDES IN CONTROL OF SODIUM TRANSPORT IN RENAL TUBULES.JOURNAL OF ENDOCRINOLOGY. VOL. 222. ISSUE 1. P. R11 -R24 171 92% 3
4 BLANCO, G , MERCER, RW , (1998) ISOZYMES OF THE NA-K-ATPASE: HETEROGENEITY IN STRUCTURE, DIVERSITY IN FUNCTION.AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. VOL. 275. ISSUE 5. P. F633 -F650 160 87% 607
5 BABULA, P , MASARIK, M , ADAM, V , PROVAZNIK, I , KIZEK, R , (2013) FROM NA+/K+-ATPASE AND CARDIAC GLYCOSIDES TO CYTOTOXICITY AND CANCER TREATMENT.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 13. ISSUE 7. P. 1069 -1087 193 76% 13
6 SCHONER, W , SCHEINER-BOBIS, G , (2007) ENDOGENOUS AND EXOGENOUS CARDIAC GLYCOSIDES AND THEIR MECHANISMS OF ACTION.AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS. VOL. 7. ISSUE 3. P. 173 -189 167 83% 86
7 SWEADNER, KJ , (1989) ISOZYMES OF THE NA+/K+-ATPASE.BIOCHIMICA ET BIOPHYSICA ACTA. VOL. 988. ISSUE 2. P. 185-220 179 80% 893
8 VERMA, SK , DAS, AK , CINGOZ, GS , GUREL, E , (2016) IN VITRO CULTURE OF DIGITALIS L. (FOXGLOVE) AND THE PRODUCTION OF CARDENOLIDES: AN UP-TO-DATE REVIEW.INDUSTRIAL CROPS AND PRODUCTS. VOL. 94. ISSUE . P. 20 -51 138 84% 0
9 LINGREL, JB , (2010) THE PHYSIOLOGICAL SIGNIFICANCE OF THE CARDIOTONIC STEROID/OUABAIN-BINDING SITE OF THE NA,K-ATPASE.ANNUAL REVIEW OF PHYSIOLOGY. VOL. 72. ISSUE . P. 395 -412 107 95% 96
10 PRASSAS, I , DIAMANDIS, EP , (2008) NOVEL THERAPEUTIC APPLICATIONS OF CARDIAC GLYCOSIDES.NATURE REVIEWS DRUG DISCOVERY. VOL. 7. ISSUE 11. P. 926-935 99 86% 218

Classes with closest relation at Level 2


Rank Class id link
1 2303 DARIERS DISEASE//CA2 ATPASE//HAILEY HAILEY DISEASE
2 2888 HEART KIDNEY//FENOLDOPAM//IBOPAMINE
3 1330 SODIUM LITHIUM COUNTERTRANSPORT//SODIUM//SALT SENSITIVITY
4 3373 ASCLEPIADACEAE//PREGNANE GLYCOSIDE//CALOTROPIS PROCERA
5 2676 LEVOSIMENDAN//CALCIUM SENSITIZER//MILRINONE
6 1393 RYANODINE RECEPTOR//EXCITATION CONTRACTION COUPLING//SARCOPLASMIC RETICULUM
7 1248 ALDOSTERONE//GITELMAN SYNDROME//BARTTER SYNDROME
8 942 HEART FAILURE//ACUTE HEART FAILURE//EUROPEAN JOURNAL OF HEART FAILURE
9 1738 BRASSINOSTEROIDS//24 EPIBRASSINOLIDE//BRASSINOLIDE
10 377 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY//PHOSPHOLAMBAN//CARDIAC & CARDIOVASCULAR SYSTEM

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