Class information for:
Level 2: TREFOIL FACTOR//CDX2//LGR5

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1844 6131 40.0 73%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
27 3       DEVELOPMENTAL BIOLOGY//DEVELOPMENT//AGR2 109777
1844 2             TREFOIL FACTOR//CDX2//LGR5 6131
6028 1                   LGR5//INTESTINAL STEM CELLS//LGR4 1541
6683 1                   SUCRASE ISOMALTASE//LACTASE PHLORIZIN HYDROLASE//LACTASE PHLORHIZIN HYDROLASE 1456
12499 1                   TREFOIL FACTOR//TREFOIL PEPTIDES//TFF DOMAIN 901
17256 1                   CDX2//CDX1//CDX 609
19363 1                   PEPSINOGEN GENE//ECPG//PROVENTRICULAR GLAND 508
23557 1                   CHOLECYSTOKININ B GASTRIN//GASTRIC RECEPTOR//SMALL INTESTINAL DEVELOPMENT 342
26550 1                   CARP 1//ERRP//JOHN D DINGLE VA MED 251
27550 1                   SPASMOLYTIC POLYPEPTIDE EXPRESSING METAPLASIA//NASHVILLE VA MED//GASTRIC STEM CELL 226
28130 1                   SCHLAFEN//SURG SERV 11S//DDK SYNDROME 213
36195 1                   EPIMORPHIN//MORPHOREGULAT//EPM PROJECT GRP 84

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TREFOIL FACTOR authKW 371166 2% 80% 93
2 CDX2 authKW 364175 3% 44% 165
3 LGR5 authKW 335669 2% 60% 112
4 TREFOIL PEPTIDES authKW 328454 1% 82% 80
5 SUCRASE ISOMALTASE authKW 291800 1% 83% 71
6 MOL BIOL MED CHEM address 187854 1% 88% 43
7 TFF DOMAIN authKW 149357 0% 100% 30
8 TFF1 authKW 135621 1% 72% 38
9 TFF3 authKW 127038 1% 73% 35
10 PS2 authKW 126741 1% 39% 66

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Gastroenterology & Hepatology 18330 17% 0% 1045
2 Cell Biology 9271 21% 0% 1299
3 Developmental Biology 7336 7% 0% 446
4 Oncology 3055 13% 0% 821
5 Biochemistry & Molecular Biology 2887 22% 0% 1326
6 Physiology 2771 8% 0% 504
7 Anatomy & Morphology 2726 3% 0% 188
8 Pathology 2123 6% 0% 362
9 Nutrition & Dietetics 1514 5% 0% 291
10 CYTOLOGY & HISTOLOGY 1254 1% 1% 45

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL BIOL MED CHEM 187854 1% 88% 43
2 MORPHOREGULAT 46336 0% 85% 11
3 NASHVILLE VA MED 36127 0% 52% 14
4 U381 35535 0% 36% 20
5 EPITHELIAL BIOL 35254 1% 21% 34
6 HISTOPATHOL UNIT 24310 1% 9% 53
7 HUBRECHT 20695 1% 7% 59
8 ADV THER EUT GASTROINTESTINAL DIS 20323 0% 58% 7
9 UNITE RECH DIFFERENCIAT CELLULAIRE INTESTINALE 20323 0% 58% 7
10 ADV THER EUT GI DIS 19906 0% 50% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 23651 3% 3% 173
2 GASTROENTEROLOGY 15736 3% 2% 206
3 JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION 9437 2% 2% 117
4 CELL AND TISSUE KINETICS 4848 0% 4% 24
5 JOURNAL OF PATHOLOGY 3432 1% 1% 63
6 CELL PROLIFERATION 3038 0% 2% 28
7 GUT 3011 1% 1% 77
8 EPITHELIAL CELL BIOLOGY 2880 0% 10% 6
9 BIOLOGY OF THE NEONATE 2866 1% 2% 39
10 CELL STEM CELL 2355 0% 2% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TREFOIL FACTOR 371166 2% 80% 93 Search TREFOIL+FACTOR Search TREFOIL+FACTOR
2 CDX2 364175 3% 44% 165 Search CDX2 Search CDX2
3 LGR5 335669 2% 60% 112 Search LGR5 Search LGR5
4 TREFOIL PEPTIDES 328454 1% 82% 80 Search TREFOIL+PEPTIDES Search TREFOIL+PEPTIDES
5 SUCRASE ISOMALTASE 291800 1% 83% 71 Search SUCRASE+ISOMALTASE Search SUCRASE+ISOMALTASE
6 TFF DOMAIN 149357 0% 100% 30 Search TFF+DOMAIN Search TFF+DOMAIN
7 TFF1 135621 1% 72% 38 Search TFF1 Search TFF1
8 TFF3 127038 1% 73% 35 Search TFF3 Search TFF3
9 PS2 126741 1% 39% 66 Search PS2 Search PS2
10 INTESTINAL STEM CELLS 114139 1% 36% 63 Search INTESTINAL+STEM+CELLS Search INTESTINAL+STEM+CELLS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KJELLEV, S , (2009) THE TREFOIL FACTOR FAMILY - SMALL PEPTIDES WITH MULTIPLE FUNCTIONALITIES.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 66. ISSUE 8. P. 1350-1369 202 91% 107
2 BARKER, N , (2014) ADULT INTESTINAL STEM CELLS: CRITICAL DRIVERS OF EPITHELIAL HOMEOSTASIS AND REGENERATION.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 15. ISSUE 1. P. 19-33 91 81% 138
3 HOFFMANN, W , JAGLA, W , (2002) CELL TYPE SPECIFIC EXPRESSION OF SECRETARY TFF PEPTIDES: COLOCALIZATION WITH MUCINS AND SYNTHESIS IN THE BRAIN.INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 213. VOL. 213. ISSUE . P. 147 -181 176 81% 70
4 CLEVERS, H , (2013) THE INTESTINAL CRYPT, A PROTOTYPE STEM CELL COMPARTMENT.CELL. VOL. 154. ISSUE 2. P. 274-284 77 73% 164
5 THIM, L , (1997) TREFOIL PEPTIDES: FROM STRUCTURE TO FUNCTION.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 53. ISSUE 11-12. P. 888 -903 136 93% 141
6 HOFFMANN, W , JAGLA, W , WIEDE, A , (2001) MOLECULAR MEDICINE OF TFF-PEPTIDES: FROM GUT TO BRAIN.HISTOLOGY AND HISTOPATHOLOGY. VOL. 16. ISSUE 1. P. 319 -334 130 80% 113
7 SAMSON, MH , (2013) QUANTITATIVE MEASUREMENTS OF TREFOIL FACTOR FAMILY PEPTIDES: POSSIBILITIES AND PITFALLS.SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION. VOL. 73. ISSUE 3. P. 193 -202 81 96% 5
8 LAN, G , LIU, J , HU, HB , YANG, RR , XIAO, P , LING, H , (2015) TREFOIL FACTORS: GASTROINTESTINAL-SPECIFIC PROTEINS ASSOCIATED WITH GASTRIC CANCER.CLINICA CHIMICA ACTA. VOL. 450. ISSUE . P. 127 -134 89 79% 2
9 MERKER, SR , WEITZ, J , STANGE, DE , (2016) GASTROINTESTINAL ORGANOIDS: HOW THEY GUT IT OUT.DEVELOPMENTAL BIOLOGY. VOL. 420. ISSUE 2. P. 239 -250 98 64% 1
10 VANBEERS, EH , BULLER, HA , GRAND, RJ , EINERHAND, AWC , DEKKER, J , (1995) INTESTINAL BRUSH-BORDER GLYCOHYDROLASES - STRUCTURE, FUNCTION, AND DEVELOPMENT.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 30. ISSUE 3. P. 197-262 164 69% 65

Classes with closest relation at Level 2


Rank Class id link
1 2404 HUMMINGBIRDS//SGLT1//NA ATPASE
2 1853 CANCER STEM CELLS//CD133//SIDE POPULATION
3 2652 LACTOSE INTOLERANCE//LACTOSE MALABSORPTION//HYDROGEN BREATH TEST
4 1425 WNT//BETA CATENIN//FRIZZLED
5 1648 EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA
6 1698 MUC1//MUCIN//MUC5AC
7 3837 PANCREATITIS ASSOCIATED PROTEIN//LITHOSTATHINE//REG PROTEIN
8 2474 ABERRANT CRYPT FOCI//ANTINEOPLASTIC DRUGS//COLON CARCINOGENESIS
9 1071 LYNCH SYNDROME//MICROSATELLITE INSTABILITY//HNPCC
10 1178 CHOLECYSTOKININ//CCK B RECEPTOR//GASTRIN

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