Class information for:
Level 2: IRON OVERLOAD//HEPCIDIN//HEMOCHROMATOSIS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
210 20783 36.9 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
332 3       ERYTHROPOIETIN//ANEMIA//FERRITIN 37752
210 2             IRON OVERLOAD//HEPCIDIN//HEMOCHROMATOSIS 20783
928 1                   IRON OVERLOAD//DEFERASIROX//THALASSEMIA 2954
1491 1                   HEPCIDIN//FERROPORTIN//HEMOJUVELIN 2628
1983 1                   HEMOCHROMATOSIS//HFE//HEREDITARY HEMOCHROMATOSIS 2397
3182 1                   IRON BIOAVAILABILITY//IRON FORTIFICATION//IRON ABSORPTION 2045
3483 1                   FERRITIN//BACTERIOFERRITIN//APOFERRITIN 1974
6139 1                   TRANSFERRIN RECEPTOR//TRANSFERRIN//DOXORUBICIN TRANSFERRIN CONJUGATE 1523
9458 1                   IRON REGULATORY PROTEIN//IRON RESPONSIVE ELEMENT//IRON REGULATORY PROTEIN 1 1154
10948 1                   TRANSFERRIN//MELANOTRANSFERRIN//HUMAN SERUM TRANSFERRIN 1022
11595 1                   FERRITIN//HEPCIDIN//IRON 969
12918 1                   IRON METAB CHELAT PROGRAM//PYRIDOXAL ISONICOTINOYL HYDRAZONE//MOL PHARMACOL PATHOL PROGRAM 872
13647 1                   THALASSEMIA MAJOR//THALASSEMIA//BETA THALASSEMIA MAJOR 822
16711 1                   HYDROXYPYRIDINONE//3 HYDROXY 4 PYRIDINONES//3 HYDROXYPYRIDIN 4 ONE 640
22972 1                   ANTIANEMIC DRUGS//IRON PROTEIN SUCCINYLATE//MALTOFER R 362
24054 1                   PLACENTAL ISOFERRITIN//P43 ISOFERRITIN//PLACENTAL FERRITIN 325
24198 1                   BETA THALASSEMIA HEMOGLOBIN E//BETA THALASSEMIC//CD1A LYMPHOCYTE 320
24516 1                   ASCORBIC ACID PALMITATE//HEPATOCELLULAR HEMOSIDEROSIS//COENZYME Q0 309
27925 1                   GOAT AND COW MILK//FERMENTED GOAT AND COW MILK//GOAT MILK 218
29990 1                   IRON POISONING//IRON OVERDOSE//IRON INTOXICATION 176
36801 1                   FERRIC LACTATE//CELLULAR CALCIUM HOMEOSTASIS//FERRIC ATP COMPLEX 73

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 IRON OVERLOAD authKW 1173388 5% 70% 1141
2 HEPCIDIN authKW 955788 4% 76% 857
3 HEMOCHROMATOSIS authKW 799179 4% 72% 755
4 FERRITIN authKW 772374 6% 39% 1341
5 HFE authKW 418697 2% 84% 340
6 THALASSEMIA authKW 352382 3% 38% 630
7 IRON authKW 313469 10% 10% 2168
8 IRON METABOLISM authKW 291654 2% 48% 414
9 DEFERASIROX authKW 266661 1% 81% 224
10 IRON ABSORPTION authKW 261489 1% 68% 261

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Hematology 48814 15% 1% 3187
2 Nutrition & Dietetics 19164 9% 1% 1776
3 Biochemistry & Molecular Biology 9320 21% 0% 4414
4 Gastroenterology & Hepatology 3996 5% 0% 1034
5 Endocrinology & Metabolism 1641 5% 0% 977
6 Biophysics 1597 4% 0% 894
7 Food Science & Technology 1511 4% 0% 885
8 Medicine, General & Internal 1338 5% 0% 1135
9 Pediatrics 1295 4% 0% 782
10 Medicine, Research & Experimental 1254 4% 0% 854

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IRON METAB 65854 0% 65% 69
2 IRON METAB CHELAT PROGRAM 52801 0% 65% 55
3 CLIN MALAD FOIE 43454 0% 74% 40
4 THALASSEMIA 42212 0% 30% 97
5 HEMOCHROMATOSIS 37721 0% 86% 30
6 THALASSAEMIA UNIT 37168 0% 65% 39
7 MICROCITEMIA 36734 0% 96% 26
8 SERV MALAD FOIE 30791 0% 51% 41
9 THALASSEMIA UNIT 27361 0% 46% 41
10 MOL PHARMACOL PATHOL PROGRAM 23444 0% 50% 32

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BLOOD CELLS MOLECULES AND DISEASES 38970 1% 12% 218
2 BIOMETALS 11991 1% 7% 120
3 BRITISH JOURNAL OF HAEMATOLOGY 11108 2% 2% 327
4 EUROPEAN JOURNAL OF HAEMATOLOGY 9820 1% 4% 162
5 ACTA HAEMATOLOGICA 9712 1% 4% 153
6 BLOOD 8405 2% 1% 463
7 HEMOGLOBIN 7980 1% 5% 112
8 JOURNAL OF NUTRITION 7375 1% 2% 265
9 AMERICAN JOURNAL OF HEMATOLOGY 6845 1% 3% 170
10 BAILLIERES CLINICAL HAEMATOLOGY-INTERNATIONAL PRACTICE AND RESEARCH 6531 0% 64% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 IRON OVERLOAD 1173388 5% 70% 1141 Search IRON+OVERLOAD Search IRON+OVERLOAD
2 HEPCIDIN 955788 4% 76% 857 Search HEPCIDIN Search HEPCIDIN
3 HEMOCHROMATOSIS 799179 4% 72% 755 Search HEMOCHROMATOSIS Search HEMOCHROMATOSIS
4 FERRITIN 772374 6% 39% 1341 Search FERRITIN Search FERRITIN
5 HFE 418697 2% 84% 340 Search HFE Search HFE
6 THALASSEMIA 352382 3% 38% 630 Search THALASSEMIA Search THALASSEMIA
7 IRON 313469 10% 10% 2168 Search IRON Search IRON
8 IRON METABOLISM 291654 2% 48% 414 Search IRON+METABOLISM Search IRON+METABOLISM
9 DEFERASIROX 266661 1% 81% 224 Search DEFERASIROX Search DEFERASIROX
10 IRON ABSORPTION 261489 1% 68% 261 Search IRON+ABSORPTION Search IRON+ABSORPTION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HARRISON, PM , AROSIO, P , (1996) FERRITINS: MOLECULAR PROPERTIES, IRON STORAGE FUNCTION AND CELLULAR REGULATION.BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. VOL. 1275. ISSUE 3. P. 161 -203 320 82% 1478
2 GANZ, T , (2013) SYSTEMIC IRON HOMEOSTASIS.PHYSIOLOGICAL REVIEWS. VOL. 93. ISSUE 4. P. 1721-1741 223 88% 173
3 JUTZ, G , VAN RIJN, P , MIRANDA, BS , BOKER, A , (2015) FERRITIN: A VERSATILE BUILDING BLOCK FOR BIONANOTECHNOLOGY.CHEMICAL REVIEWS. VOL. 115. ISSUE 4. P. 1653 -1701 249 65% 44
4 PENNELL, DJ , UDELSON, JE , ARAI, AE , BOZKURT, B , COHEN, AR , GALANELLO, R , HOFFMAN, TM , KIERNAN, MS , LERAKIS, S , PIGA, A , ET AL (2013) CARDIOVASCULAR FUNCTION AND TREATMENT IN -THALASSEMIA MAJOR: A CONSENSUS STATEMENT FROM THE AMERICAN HEART ASSOCIATION.CIRCULATION. VOL. 128. ISSUE 3. P. 281 -308 229 84% 47
5 MARQUES, O , DA SILVA, BM , PORTO, G , LOPES, C , (2014) IRON HOMEOSTASIS IN BREAST CANCER.CANCER LETTERS. VOL. 347. ISSUE 1. P. 1 -14 243 79% 19
6 GKOUVATSOS, K , PAPANIKOLAOU, G , PANTOPOULOS, K , (2012) REGULATION OF IRON TRANSPORT AND THE ROLE OF TRANSFERRIN.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. VOL. 1820. ISSUE 3. P. 188 -202 197 83% 105
7 CHUA, ACG , GRAHAM, RM , TRINDER, D , OLYNYK, JK , (2007) THE REGULATION OF CELLULAR IRON METABOLISM.CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES. VOL. 44. ISSUE 5-6. P. 413 -459 253 85% 73
8 LAWEN, A , LANE, DJR , (2013) MAMMALIAN IRON HOMEOSTASIS IN HEALTH AND DISEASE: UPTAKE, STORAGE, TRANSPORT, AND MOLECULAR MECHANISMS OF ACTION.ANTIOXIDANTS & REDOX SIGNALING. VOL. 18. ISSUE 18. P. 2473 -2507 263 68% 32
9 EBRAHIMI, KH , HAGEDOORN, PL , HAGEN, WR , (2015) UNITY IN THE BIOCHEMISTRY OF THE IRON-STORAGE PROTEINS FERRITIN AND BACTERIOFERRITIN.CHEMICAL REVIEWS. VOL. 115. ISSUE 1. P. 295 -326 153 78% 32
10 RICHARDSON, DR , PONKA, P , (1997) THE MOLECULAR MECHANISMS OF THE METABOLISM AND TRANSPORT OF IRON IN NORMAL AND NEOPLASTIC CELLS.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON BIOMEMBRANES. VOL. 1331. ISSUE 1. P. 1 -40 274 70% 368

Classes with closest relation at Level 2


Rank Class id link
1 388 ERYTHROPOIETIN//ANEMIA//IRON DEFICIENCY
2 2943 DICEROS BICORNIS//BLACK RHINOCEROS//MINERAL NUTR
3 1409 SIDEROPHORE//COLICIN//PYOVERDIN
4 667 ZINC//ZINC DEFICIENCY//COPPER DEFICIENCY
5 1296 HEME OXYGENASE//PORPHYRIA//HEME OXYGENASE 1
6 3688 LIPOCALIN 2//APOLIPOPROTEIN D//ZINC ALPHA 2 GLYCOPROTEIN
7 3934 BDSI BIOPHYS DYNAM INTEGRATED SYST//ESCHERICHIA COLI BW 25113//FE ASCORBATE PEROXIDATION
8 1768 HEMOGLOBIN//ALPHA THALASSEMIA//HEMOGLOBINOPATHIES
9 3654 FERRIC NITRILOTRIACETATE//SECT CHEMOPREVENT NUTR TOXICOL//EDTA
10 2229 ALUMINUM//STATE COORDINAT CHEM CHINA//ALUMINUM EXPOSURE

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