Class information for:
Level 2: UROCORTIN//CORTICOTROPIN RELEASING FACTOR//CRF

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2334 4427 47.1 82%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
127 3       OXYTOCIN//BEHAVIORAL SCIENCES//VASOPRESSIN 67291
2334 2             UROCORTIN//CORTICOTROPIN RELEASING FACTOR//CRF 4427
523 1                   UROCORTIN//CORTICOTROPIN RELEASING FACTOR//CRF 3343
14703 1                   MOTHERS BABIES//SIR QUINTON HAZELL MOL MED//PLACENTAL CRH 755
23931 1                   CUSHINGS SYNDROME//ADRENAL UNIT//ACTH INDEPENDENT NODULAR ADRENAL HYPERPLASIA 329

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UROCORTIN authKW 1900048 7% 83% 332
2 CORTICOTROPIN RELEASING FACTOR authKW 1400680 11% 40% 504
3 CRF authKW 685954 6% 35% 282
4 CORTICOTROPIN RELEASING HORMONE authKW 557887 7% 26% 307
5 CRF RECEPTOR authKW 408589 2% 74% 80
6 CORTICOTROPIN RELEASING FACTOR RECEPTOR authKW 366469 2% 78% 68
7 CRH authKW 354414 4% 28% 182
8 UROCORTIN 2 authKW 304643 1% 94% 47
9 CLAYTON FDN S PEPTIDE BIOL address 231799 3% 26% 128
10 CORTICOTROPIN RELEASING FACTOR CRF authKW 206809 1% 50% 60

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Endocrinology & Metabolism 23792 29% 0% 1271
2 Neurosciences 13078 33% 0% 1446
3 Pharmacology & Pharmacy 3375 18% 0% 803
4 Obstetrics & Gynecology 3114 9% 0% 386
5 Behavioral Sciences 1278 4% 0% 189
6 Psychiatry 1256 7% 0% 315
7 Reproductive Biology 803 3% 0% 132
8 Physiology 682 5% 0% 233
9 Chemistry, Medicinal 337 3% 0% 149
10 Biochemistry & Molecular Biology 287 11% 0% 509

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLAYTON FDN S PEPTIDE BIOL 231799 3% 26% 128
2 SIR QUINTON HAZELL MOL MED 98146 0% 65% 22
3 MOL NEUROENDOCRINOL 58216 1% 17% 49
4 MOTHERS BABIES 40823 1% 17% 34
5 NEURONAL STRUCT FUNCT 37050 0% 24% 22
6 COMM NEUROBIOL ADDICT DISORDERS 28580 1% 12% 36
7 JIANGSU PROV CARDIOVASC DIS MOL INTERVE 24509 0% 44% 8
8 CLIN NEUROENDOCRINOL BRANCH 22980 0% 15% 22
9 CURE DIGEST DIS 22874 1% 11% 31
10 CHRISTCHURCH CARDIOENDOCRINE GRP 22325 0% 15% 21

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEPTIDES 16144 3% 2% 144
2 ENDOCRINOLOGY 6902 4% 1% 160
3 NEUROPEPTIDES 5670 1% 2% 46
4 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 5660 3% 1% 142
5 BRAIN RESEARCH 4988 4% 0% 190
6 NEUROPSYCHOPHARMACOLOGY 3729 1% 1% 53
7 REGULATORY PEPTIDES 3424 1% 1% 49
8 JOURNAL OF NEUROENDOCRINOLOGY 2754 1% 1% 36
9 NEUROENDOCRINOLOGY 2603 1% 1% 42
10 HORMONES AND BEHAVIOR 2088 1% 1% 32

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 UROCORTIN 1900048 7% 83% 332 Search UROCORTIN Search UROCORTIN
2 CORTICOTROPIN RELEASING FACTOR 1400680 11% 40% 504 Search CORTICOTROPIN+RELEASING+FACTOR Search CORTICOTROPIN+RELEASING+FACTOR
3 CRF 685954 6% 35% 282 Search CRF Search CRF
4 CORTICOTROPIN RELEASING HORMONE 557887 7% 26% 307 Search CORTICOTROPIN+RELEASING+HORMONE Search CORTICOTROPIN+RELEASING+HORMONE
5 CRF RECEPTOR 408589 2% 74% 80 Search CRF+RECEPTOR Search CRF+RECEPTOR
6 CORTICOTROPIN RELEASING FACTOR RECEPTOR 366469 2% 78% 68 Search CORTICOTROPIN+RELEASING+FACTOR+RECEPTOR Search CORTICOTROPIN+RELEASING+FACTOR+RECEPTOR
7 CRH 354414 4% 28% 182 Search CRH Search CRH
8 UROCORTIN 2 304643 1% 94% 47 Search UROCORTIN+2 Search UROCORTIN+2
9 CORTICOTROPIN RELEASING FACTOR CRF 206809 1% 50% 60 Search CORTICOTROPIN+RELEASING+FACTOR+CRF Search CORTICOTROPIN+RELEASING+FACTOR+CRF
10 UROCORTIN 1 187722 1% 83% 33 Search UROCORTIN+1 Search UROCORTIN+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FEKETE, EM , ZORRILLA, EP , (2007) PHYSIOLOGY, PHARMACOLOGY, AND THERAPEUTIC RELEVANCE OF UROCORTINS IN MAMMALS: ANCIENT CRF PARALOGS.FRONTIERS IN NEUROENDOCRINOLOGY. VOL. 28. ISSUE 1. P. 1-27 264 89% 126
2 BALE, TL , VALE, WW , (2004) CRF AND CRF RECEPTORS: ROLE IN STRESS RESPONSIVITY AND OTHER BEHAVIORS.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 44. ISSUE . P. 525-557 156 87% 659
3 RONAN, PJ , SUMMERS, CH , (2011) MOLECULAR SIGNALING AND TRANSLATIONAL SIGNIFICANCE OF THE CORTICOTROPIN RELEASING FACTOR SYSTEM.BRAIN AS A DRUG TARGET. VOL. 98. ISSUE . P. 235 -292 260 63% 6
4 PETRAGLIA, F , IMPERATORE, A , CHALLIS, JRG , (2010) NEUROENDOCRINE MECHANISMS IN PREGNANCY AND PARTURITION.ENDOCRINE REVIEWS. VOL. 31. ISSUE 6. P. 783 -816 213 66% 68
5 ZORRILLA, EP , KOOB, GF , (2004) THE THERAPEUTIC POTENTIAL OF CRF1 ANTAGONISTS FOR ANXIETY.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 13. ISSUE 7. P. 799-828 236 70% 111
6 HILLHOUSE, EW , GRAMMATOPOULOS, DK , (2006) THE MOLECULAR MECHANISMS UNDERLYING THE REGULATION OF THE BIOLOGICAL ACTIVITY OF CORTICOTROPIN-RELEASING HORMONE RECEPTORS: IMPLICATIONS FOR PHYSIOLOGY AND PATHOPHYSIOLOGY.ENDOCRINE REVIEWS. VOL. 27. ISSUE 3. P. 260-286 174 75% 188
7 LIAPAKIS, G , VENIHAKI, M , MARGIORIS, A , GRIGORIADIS, D , GKOUNTELIAS, K , (2011) MEMBERS OF CRF FAMILY AND THEIR RECEPTORS: FROM PAST TO FUTURE.CURRENT MEDICINAL CHEMISTRY. VOL. 18. ISSUE 17. P. 2583 -2600 173 81% 12
8 WALCZEWSKA, J , DZIEZA-GRUDNIK, A , SIGA, O , GRODZICKI, T , (2014) THE ROLE OF UROCORTINS IN THE CARDIOVASCULAR SYSTEM.JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. VOL. 65. ISSUE 6. P. 753 -766 133 92% 6
9 HENCKENS, MJAG , DEUSSING, JM , CHEN, A , (2016) REGION-SPECIFIC ROLES OF THE CORTICOTROPIN-RELEASING FACTOR-UROCORTIN SYSTEM IN STRESS.NATURE REVIEWS NEUROSCIENCE. VOL. 17. ISSUE 10. P. 636 -651 165 75% 0
10 TACHE, Y , MILLION, M , (2015) ROLE OF CORTICOTROPIN-RELEASING FACTOR SIGNALING IN STRESS-RELATED ALTERATIONS OF COLONIC MOTILITY AND HYPERALGESIA.JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY. VOL. 21. ISSUE 1. P. 8 -24 139 70% 17

Classes with closest relation at Level 2


Rank Class id link
1 3735 UROTENSIN II//GPR14//UT RECEPTOR
2 284 PRENATAL STRESS//CORTICOSTERONE//MATERNAL SEPARATION
3 276 OXYTOCIN//VASOPRESSIN//HYPONATREMIA
4 2294 MELANOCORTIN//MELANOCORTIN RECEPTOR//MELANOCORTIN 4 RECEPTOR
5 1753 OREXIN//GALANIN//HYPOCRETIN
6 955 PRETERM LABOR//CERVICAL LENGTH//PRETERM BIRTH
7 121 OPIOID RECEPTORS//MORPHINE//DELTA OPIOID RECEPTOR
8 3497 NOCICEPTIN//ORPHANIN FQ//NOCICEPTIN ORPHANIN FQ
9 909 CONGENITAL ADRENAL HYPERPLASIA//21 HYDROXYLASE DEFICIENCY//ENDOCRINE RESEARCH
10 1819 CORTISOL//DIGIT RATIO//PSYCHONEUROENDOCRINOLOGY

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