Class information for:
Level 2: TRAMADOL//DIPYRONE//TAPENTADOL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2563 3711 27.4 64%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
59 3       ANESTHESIOLOGY//PAIN//CHRONIC PAIN 88506
2563 2             TRAMADOL//DIPYRONE//TAPENTADOL 3711
8337 1                   TRAMADOL//TAPENTADOL//O DESMETHYLTRAMADOL 1264
14604 1                   DRUG INDUCED THROMBOCYTOPENIA//DRUG DEPENDENT ANTIBODIES//DRUG INDUCED IMMUNE HEMOLYTIC ANEMIA 760
16177 1                   AGRANULOCYTOSIS//DRUG INDUCED AGRANULOCYTOSIS//EVALUATION SCORE 668
17600 1                   INTRAVENOUS ACETAMINOPHEN//PARACETAMOL//PROPACETAMOL 591
21214 1                   DIPYRONE//METAMIZOL//PIFIR MODEL 428

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRAMADOL authKW 2611828 16% 55% 581
2 DIPYRONE authKW 460925 3% 51% 109
3 TAPENTADOL authKW 314643 2% 65% 59
4 O DESMETHYLTRAMADOL authKW 216196 1% 91% 29
5 AGRANULOCYTOSIS authKW 186857 2% 26% 87
6 METAMIZOL authKW 176197 1% 55% 39
7 PARACETAMOL authKW 153504 5% 9% 197
8 INTRAVENOUS ACETAMINOPHEN authKW 145108 1% 84% 21
9 ANALGESICS OPIOID TRAMADOL authKW 125125 0% 89% 17
10 PROPACETAMOL authKW 109980 1% 70% 19

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Anesthesiology 13390 12% 0% 432
2 Pharmacology & Pharmacy 8712 30% 0% 1097
3 Medicine, General & Internal 2864 14% 0% 525
4 Hematology 2859 9% 0% 340
5 Toxicology 480 4% 0% 155
6 Chemistry, Analytical 321 6% 0% 205
7 Critical Care Medicine 228 2% 0% 70
8 Medicine, Research & Experimental 209 4% 0% 149
9 Pediatrics 159 3% 0% 123
10 Clinical Neurology 111 4% 0% 150

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RUSH PAIN 57585 0% 100% 7
2 MED AFFAIRS EUROPE AUSTRALIA 49359 0% 100% 6
3 LAFAA CONTRACT 24679 0% 100% 3
4 NORTHSHORE PAIN 24679 0% 100% 3
5 GLOBAL PRECLIN DEV 18515 0% 17% 13
6 CBMA MOL BIOL ENVIRONM 16453 0% 100% 2
7 CLIN DEV ANALGES 16453 0% 100% 2
8 CLIN PHARMACOLIDIPAZ 16453 0% 100% 2
9 GLOBAL BIOMETR GRUNENTHAL INNOVAT 16453 0% 100% 2
10 GRUNENTHAL INNOVAT GLOBAL BIOMETR 16453 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 3954 2% 1% 59
2 TRANSFUSION 3643 2% 1% 59
3 EUROPEAN JOURNAL OF ANAESTHESIOLOGY 2739 1% 1% 32
4 PAIN PRACTICE 2524 0% 2% 14
5 BRITISH JOURNAL OF ANAESTHESIA 2193 1% 1% 50
6 EUROPEAN JOURNAL OF PAIN 2078 1% 1% 23
7 ANNALS OF PHARMACOTHERAPY 1813 1% 1% 35
8 CURRENT MEDICAL RESEARCH AND OPINION 1720 1% 1% 31
9 ANESTHESIA AND ANALGESIA 1551 1% 0% 54
10 PEDIATRIC ANESTHESIA 1533 1% 1% 20

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TRAMADOL 2611828 16% 55% 581 Search TRAMADOL Search TRAMADOL
2 DIPYRONE 460925 3% 51% 109 Search DIPYRONE Search DIPYRONE
3 TAPENTADOL 314643 2% 65% 59 Search TAPENTADOL Search TAPENTADOL
4 O DESMETHYLTRAMADOL 216196 1% 91% 29 Search O+DESMETHYLTRAMADOL Search O+DESMETHYLTRAMADOL
5 AGRANULOCYTOSIS 186857 2% 26% 87 Search AGRANULOCYTOSIS Search AGRANULOCYTOSIS
6 METAMIZOL 176197 1% 55% 39 Search METAMIZOL Search METAMIZOL
7 PARACETAMOL 153504 5% 9% 197 Search PARACETAMOL Search PARACETAMOL
8 INTRAVENOUS ACETAMINOPHEN 145108 1% 84% 21 Search INTRAVENOUS+ACETAMINOPHEN Search INTRAVENOUS+ACETAMINOPHEN
9 ANALGESICS OPIOID TRAMADOL 125125 0% 89% 17 Search ANALGESICS+OPIOID+TRAMADOL Search ANALGESICS+OPIOID+TRAMADOL
10 PROPACETAMOL 109980 1% 70% 19 Search PROPACETAMOL Search PROPACETAMOL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GROND, S , SABLOTZKI, A , (2004) CLINICAL PHARMACOLOGY OF TRAMADOL.CLINICAL PHARMACOKINETICS. VOL. 43. ISSUE 13. P. 879-923 181 80% 383
2 LEPPERT, W , (2009) TRAMADOL AS AN ANALGESIC FOR MILD TO MODERATE CANCER PAIN.PHARMACOLOGICAL REPORTS. VOL. 61. ISSUE 6. P. 978 -992 63 82% 47
3 MCNICOL, ED , FERGUSON, MC , HAROUTOUNIAN, S , CARR, DB , SCHUMANN, R , (2016) SINGLE DOSE INTRAVENOUS PARACETAMOL OR INTRAVENOUS PROPACETAMOL FOR POSTOPERATIVE PAIN.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 5. P. - 67 66% 1
4 SHIPTON, EA , (2000) TRAMADOL - PRESENT AND FUTURE.ANAESTHESIA AND INTENSIVE CARE. VOL. 28. ISSUE 4. P. 363 -374 77 81% 97
5 SCOTT, LJ , PERRY, CM , (2000) TRAMADOL - A REVIEW OF ITS USE IN PERIOPERATIVE PAIN.DRUGS. VOL. 60. ISSUE 1. P. 139 -176 65 73% 247
6 NIKOLOVA, I , TENCHEVA, J , VOINIKOV, J , PETKOVA, V , BENBASAT, N , DANCHEV, N , (2012) METAMIZOLE: A REVIEW PROFILE OF A WELL-KNOWN "FORGOTTEN" DRUG. PART I: PHARMACEUTICAL AND NONCLINICAL PROFILE.BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT. VOL. 26. ISSUE 6. P. 3329-3337 61 68% 13
7 RADBRUCH, L , GROND, S , LEHMANN, KA , (1996) A RISK-BENEFIT ASSESSMENT OF TRAMADOL IN THE MANAGEMENT OF PAIN.DRUG SAFETY. VOL. 15. ISSUE 1. P. 8-29 65 92% 65
8 MARZUILLO, P , CALLIGARIS, L , BARBI, E , (2014) TRAMADOL CAN SELECTIVELY MANAGE MODERATE PAIN IN CHILDREN FOLLOWING EUROPEAN ADVICE LIMITING CODEINE USE.ACTA PAEDIATRICA. VOL. 103. ISSUE 11. P. 1110 -1116 43 88% 1
9 LEE, CR , MCTAVISH, D , SORKIN, EM , (1993) TRAMADOL - A PRELIMINARY REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES, AND THERAPEUTIC POTENTIAL IN ACUTE AND CHRONIC PAIN STATES.DRUGS. VOL. 46. ISSUE 2. P. 313-340 54 90% 299
10 LASSEN, D , DAMKIER, P , BROSEN, K , (2015) THE PHARMACOGENETICS OF TRAMADOL.CLINICAL PHARMACOKINETICS. VOL. 54. ISSUE 8. P. 825 -836 45 66% 8

Classes with closest relation at Level 2


Rank Class id link
1 2479 BREAKTHROUGH PAIN//CANCER PAIN//FENTANYL
2 3268 TONSILLECTOMY//ADENOIDECTOMY//TONSILLOTOMY
3 1613 ACETAMINOPHEN//DRUG INDUCED LIVER INJURY//HEPATOTOXICITY
4 4008 DIHYDRALAZINE SULFATE//DRUG INDUCED LUPUS//HYDRALAZINE HYDROCHLORIDE
5 466 NSAIDS//NON STEROIDAL ANTI INFLAMMATORY DRUGS//COX 2 INHIBITORS
6 141 ANESTHESIOLOGY//BUPIVACAINE//REGIONAL ANESTHESIA AND PAIN MEDICINE
7 1858 VETERINARY ANAESTHESIA AND ANALGESIA//MEDETOMIDINE//XYLAZINE
8 3951 NEFOPAM//ACRIVASTINE//METHAPYRILENE
9 2067 IMMUNE THROMBOCYTOPENIA//IDIOPATHIC THROMBOCYTOPENIC PURPURA//IMMUNE THROMBOCYTOPENIC PURPURA
10 2978 PHARMACOVIGILANCE//ADVERSE DRUG REACTIONS//DRUG SAFETY

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