Class information for:
Level 2: NSAIDS//NON STEROIDAL ANTI INFLAMMATORY DRUGS//COX 2 INHIBITORS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
466 15930 31.5 63%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
275 3       NSAIDS//CYCLOOXYGENASE//CYCLOOXYGENASE 2 43399
466 2             NSAIDS//NON STEROIDAL ANTI INFLAMMATORY DRUGS//COX 2 INHIBITORS 15930
1326 1                   NSAIDS//NON STEROIDAL ANTI INFLAMMATORY DRUGS//LOW DOSE ASPIRIN 2716
2243 1                   CYCLOOXYGENASE//PROSTAGLANDIN H SYNTHASE//AB HANCOCK JR MEM CANC 2310
6761 1                   PRACTICE POINTS//6 KETO PROSTAGLANDIN F1 ALPHA EXCRETION//ACUTE NONOLIGURIC RENAL FAILURE 1446
7453 1                   CHIRAL INVERSION//DEXIBUPROFEN//IBUPROFEN 1365
9386 1                   PAIN NUFFIELD ANAESTHET//THIRD MOLAR SURGERY//DENTAL PAIN 1160
11362 1                   COXIBS//SOLUMATRIX//ROFECOXIB 987
13403 1                   ACECLOFENAC//ETHAMSYLATE//MEFENAMIC ACID 840
14478 1                   ACYL GLUCURONIDE//ZOMEPIRAC//DRUG PROTEIN ADDUCTS 767
15959 1                   MELOXICAM//TENOXICAM//PIROXICAM 681
17116 1                   ETODOLAC//EUROPEAN JOURNAL OF RHEUMATOLOGY AND INFLAMMATION//CAS 41340 25 4 617
18146 1                   DICLOFENAC EPOLAMINE//TOPICAL NSAIDS//DICLOFENAC N 2 HYDROXYETHYLPYRROLIDINE 564
20630 1                   NABUMETONE//6 METHOXY 2 NAPHTHYLACETIC ACID//NAPROXEN 451
20784 1                   NIMESULIDE//CAS 51803 78 2//AULINR 445
21642 1                   GEORGE M OBRIEN KIDNEY UROL DIS//GEORGE OBRIEN KIDNEY UROL DIS//MACULA DENSA 411
25566 1                   OXAPROZIN//4 5 DIARYLOXAZOLE//4 ACETAMIDOPHENYL 2 5 P TOLUYL 1 METHYLPYRROLEACETATE PHARMACOKINETICS 278
26566 1                   DRUG INDUCED ASEPTIC MENINGITIS//ASEPTIC MENINGITIS//IBUPROFEN TOXICITY 251
29518 1                   ACEMETACIN//1 1 DIOXO 1 2 THIAZINE 6 CARBALDEHYDES//ACEMETACIN ACE 185
30067 1                   ZALTOPROFEN//CAS 18683 91 5//CHILLS DRUG THERAPY 175
30350 1                   LICOFELONE//TEPOXALIN//2 2 DIMETHYL 6 4 CHLOROPHENYL 7 PHENYL 2 3 DIHYDRO 1H PYRROLIZINE 5 YL ACETIC ACID 170
34451 1                   TALNIFLUMATE//GUAR ACETATE//NEUROL NEUROL SURG ADJUNCT REHABIL MED 111

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NSAIDS authKW 420455 5% 25% 876
2 NON STEROIDAL ANTI INFLAMMATORY DRUGS authKW 304734 4% 23% 697
3 COX 2 INHIBITORS authKW 192717 2% 40% 252
4 ROFECOXIB authKW 155260 1% 45% 182
5 CYCLOOXYGENASE authKW 127945 3% 14% 483
6 DICLOFENAC authKW 125015 2% 20% 328
7 COXIBS authKW 123432 1% 56% 115
8 CELECOXIB authKW 99372 2% 19% 271
9 IBUPROFEN authKW 86050 2% 13% 340
10 NABUMETONE authKW 85248 0% 64% 70

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 55950 35% 1% 5653
2 Rheumatology 23084 7% 1% 1142
3 Chemistry, Medicinal 10974 8% 1% 1344
4 Medicine, General & Internal 10289 13% 0% 2088
5 Gastroenterology & Hepatology 5720 6% 0% 1032
6 Chemistry, Analytical 4184 8% 0% 1333
7 Medicine, Research & Experimental 2694 6% 0% 956
8 Toxicology 834 3% 0% 473
9 Biochemical Research Methods 557 3% 0% 473
10 Urology & Nephrology 432 2% 0% 367

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PAIN NUFFIELD ANAESTHET 55037 0% 55% 52
2 AB HANCOCK JR MEM CANC 25391 0% 40% 33
3 GEORGE M OBRIEN KIDNEY UROL DIS 16750 0% 49% 18
4 GEORGE OBRIEN KIDNEY UROL DIS 9574 0% 100% 5
5 OFF CLIN TRAINING 9115 0% 53% 9
6 CLIN PHARMACOKINET BIOAVAI IL 7660 0% 100% 4
7 OXFORD RADCLIFFE HOSP 6425 0% 21% 16
8 PAIN NUFFIELD CLIN NEUROSCI 6326 0% 25% 13
9 MICROBIAL BIOTRANSFORMAT GRP 5745 0% 100% 3
10 STUDI FIS MACROMOL 5745 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF RHEUMATOLOGY AND INFLAMMATION 61963 0% 45% 72
2 CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL 31833 2% 6% 284
3 CURRENT MEDICAL RESEARCH AND OPINION 18806 1% 5% 211
4 JOURNAL OF CLINICAL PHARMACOLOGY 13918 1% 4% 201
5 ALIMENTARY PHARMACOLOGY & THERAPEUTICS 11249 1% 3% 197
6 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 10473 1% 4% 157
7 CLINICAL THERAPEUTICS 10117 1% 3% 164
8 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 8923 1% 2% 198
9 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 7998 1% 2% 175
10 JOURNAL OF RHEUMATOLOGY 6588 1% 2% 215

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NSAIDS 420455 5% 25% 876 Search NSAIDS Search NSAIDS
2 NON STEROIDAL ANTI INFLAMMATORY DRUGS 304734 4% 23% 697 Search NON+STEROIDAL+ANTI+INFLAMMATORY+DRUGS Search NON+STEROIDAL+ANTI+INFLAMMATORY+DRUGS
3 COX 2 INHIBITORS 192717 2% 40% 252 Search COX+2+INHIBITORS Search COX+2+INHIBITORS
4 ROFECOXIB 155260 1% 45% 182 Search ROFECOXIB Search ROFECOXIB
5 CYCLOOXYGENASE 127945 3% 14% 483 Search CYCLOOXYGENASE Search CYCLOOXYGENASE
6 DICLOFENAC 125015 2% 20% 328 Search DICLOFENAC Search DICLOFENAC
7 COXIBS 123432 1% 56% 115 Search COXIBS Search COXIBS
8 CELECOXIB 99372 2% 19% 271 Search CELECOXIB Search CELECOXIB
9 IBUPROFEN 86050 2% 13% 340 Search IBUPROFEN Search IBUPROFEN
10 NABUMETONE 85248 0% 64% 70 Search NABUMETONE Search NABUMETONE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CHEN, YF , JOBANPUTRA, P , BARTON, P , BRYAN, S , FRY-SMITH, A , HARRIS, G , TAYLOR, RS , (2008) CYCLOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (ETODOLAC, MELOXICAM, CELECOXIB, ROFECOXIB, ETORICOXIB, VALDECOXIB AND LUMIRACOXIB) FOR OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS: A SYSTEMATIC REVIEW AND ECONOMIC EVALUATION.HEALTH TECHNOLOGY ASSESSMENT. VOL. 12. ISSUE 11. P. 1 -+ 233 82% 102
2 SIMMONS, DL , BOTTING, RM , HLA, T , (2004) CYCLOOXYGENASE ISOZYMES: THE BIOLOGY OF PROSTAGLANDIN SYNTHESIS AND INHIBITION.PHARMACOLOGICAL REVIEWS. VOL. 56. ISSUE 3. P. 387-437 203 46% 742
3 STAREK, M , KRZEK, J , (2009) A REVIEW OF ANALYTICAL TECHNIQUES FOR DETERMINATION OF OXICAMS, NIMESULIDE AND NABUMETONE.TALANTA. VOL. 77. ISSUE 3. P. 925-942 141 92% 39
4 SCARPIGNATO, C , LANAS, A , BLANDIZZI, C , LEMS, WF , HERMANN, M , HUNT, RH , (2015) SAFE PRESCRIBING OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS IN PATIENTS WITH OSTEOARTHRITIS - AN EXPERT CONSENSUS ADDRESSING BENEFITS AS WELL AS GASTROINTESTINAL AND CARDIOVASCULAR RISKS.BMC MEDICINE. VOL. 13. ISSUE . P. - 135 66% 20
5 DAVIES, NM , (1998) CLINICAL PHARMACOKINETICS OF IBUPROFEN - THE FIRST 30 YEARS.CLINICAL PHARMACOKINETICS. VOL. 34. ISSUE 2. P. 101 -154 194 75% 168
6 SMITH, WL , DEWITT, DL , GARAVITO, RM , (2000) CYCLOOXYGENASES: STRUCTURAL, CELLULAR, AND MOLECULAR BIOLOGY.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 69. ISSUE . P. 145 -182 128 52% 1686
7 BROWN, TJ , HOOPER, L , ELLIOTT, RA , PAYNE, K , WEBB, R , ROBERTS, C , ROSTOM, A , SYMMONS, D , (2006) A COMPARISON OF THE COST-EFFECTIVENESS OF FIVE STRATEGIES FOR THE PREVENTION OF NON-STEROIDAL ANTI-INFLAMMATORY DRUG-INDUCED GASTROINTESTINAL TOXICITY: A SYSTEMATIC REVIEW WITH ECONOMIC MODELLING.HEALTH TECHNOLOGY ASSESSMENT. VOL. 10. ISSUE 38. P. 1 -+ 143 87% 55
8 LANZA, FL , CHAN, FKL , QUIGLEY, EMM , (2009) GUIDELINES FOR PREVENTION OF NSAID-RELATED ULCER COMPLICATIONS.AMERICAN JOURNAL OF GASTROENTEROLOGY. VOL. 104. ISSUE 3. P. 728 -738 86 91% 232
9 LAINE, L , WHITE, WB , ROSTOM, A , HOCHBERG, M , (2008) COX-2 SELECTIVE INHIBITORS IN THE TREATMENT OF OSTEOARTHRITIS.SEMINARS IN ARTHRITIS AND RHEUMATISM. VOL. 38. ISSUE 3. P. 165 -187 122 82% 42
10 CHAKRABORTI, AK , GARG, SK , KUMAR, R , MOTIWALA, HF , JADHAVAR, PS , (2010) PROGRESS IN COX-2 INHIBITORS: A JOURNEY SO FAR.CURRENT MEDICINAL CHEMISTRY. VOL. 17. ISSUE 15. P. 1563-1593 115 77% 61

Classes with closest relation at Level 2


Rank Class id link
1 2305 CYCLOOXYGENASE 2//COX 2//CELECOXIB
2 2563 TRAMADOL//DIPYRONE//TAPENTADOL
3 4136 FENCAMFAMINE//DEZOCINE//MAZAPERTINE
4 1311 PROSTAGLANDIN D 2//CRTH2//MOL BEHAV BIOL
5 3171 UROMODULIN//TAMM HORSFALL PROTEIN//ANALGESIC NEPHROPATHY
6 3405 LOTEPREDNOL ETABONATE//PRODRUG//ANTEDRUG
7 590 GASTRIC ULCER//GASTROPROTECTION//SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
8 1858 VETERINARY ANAESTHESIA AND ANALGESIA//MEDETOMIDINE//XYLAZINE
9 966 CLOPIDOGREL//PRASUGREL//TICAGRELOR
10 1822 GAP JUNCTION//CONNEXIN//CONNEXIN43

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