Class information for:
Level 3: NSAIDS//CYCLOOXYGENASE//CYCLOOXYGENASE 2

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
275 43399 35.6 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
275 3       NSAIDS//CYCLOOXYGENASE//CYCLOOXYGENASE 2 43399
466 2             NSAIDS//NON STEROIDAL ANTI INFLAMMATORY DRUGS//COX 2 INHIBITORS 15930
566 2             EPOXYEICOSATRIENOIC ACIDS//LIPOXYGENASE//LEUKOTRIENES 14430
1311 2             PROSTAGLANDIN D 2//CRTH2//MOL BEHAV BIOL 8520
2305 2             CYCLOOXYGENASE 2//COX 2//CELECOXIB 4519

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 NSAIDS authKW 277897 3% 34% 1178
2 CYCLOOXYGENASE authKW 198819 2% 29% 995
3 CYCLOOXYGENASE 2 authKW 196073 2% 28% 990
4 NON STEROIDAL ANTI INFLAMMATORY DRUGS authKW 182255 2% 29% 892
5 LIPOXYGENASE authKW 177826 2% 35% 728
6 COX 2 authKW 177596 2% 28% 901
7 CELECOXIB authKW 173828 1% 42% 592
8 EPOXYEICOSATRIENOIC ACIDS authKW 171857 1% 80% 306
9 LEUKOTRIENES authKW 170644 2% 36% 671
10 PROSTAGLANDINS & OTHER LIPID MEDIATORS journal 141631 1% 34% 605

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 72649 25% 1% 11036
2 Biochemistry & Molecular Biology 15266 19% 1% 8437
3 Chemistry, Medicinal 14020 6% 1% 2622
4 Rheumatology 8414 3% 1% 1227
5 Medicine, General & Internal 6837 7% 1% 3234
6 Medicine, Research & Experimental 5466 5% 1% 2325
7 Cell Biology 5285 8% 0% 3339
8 Peripheral Vascular Diseases 4400 4% 1% 1612
9 Gastroenterology & Hepatology 4015 4% 1% 1614
10 Endocrinology & Metabolism 3734 5% 0% 2103

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EXPT THER EUT REPERFUS INJURY 97049 1% 57% 245
2 MOL BEHAV BIOL 41314 0% 48% 122
3 EICOSANOID 23015 0% 86% 38
4 CHEM 2 22754 0% 49% 67
5 PAIN NUFFIELD ANAESTHET 20136 0% 55% 52
6 PHYSIOL CHEM 2 17252 0% 29% 84
7 ANESTHESIOL PERIOPERAT PAIN MED 16578 0% 13% 188
8 CLAUDE PEPPER 15417 0% 48% 46
9 AB HANCOCK JR MEM CANC 14342 0% 50% 41
10 MINASE 14286 0% 29% 70

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROSTAGLANDINS & OTHER LIPID MEDIATORS 141631 1% 34% 605
2 ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH 137124 1% 50% 394
3 PROSTAGLANDINS 92334 1% 30% 441
4 PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 53547 1% 16% 491
5 PROSTAGLANDINS LEUKOTRIENES AND MEDICINE 45839 1% 27% 240
6 EUROPEAN JOURNAL OF RHEUMATOLOGY AND INFLAMMATION 22653 0% 45% 72
7 EICOSANOIDS 14899 0% 42% 51
8 CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL 13916 1% 7% 314
9 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 9974 1% 3% 573
10 PROSTAGLANDINS AND MEDICINE 7960 0% 22% 51

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 NSAIDS 277897 3% 34% 1178 Search NSAIDS Search NSAIDS
2 CYCLOOXYGENASE 198819 2% 29% 995 Search CYCLOOXYGENASE Search CYCLOOXYGENASE
3 CYCLOOXYGENASE 2 196073 2% 28% 990 Search CYCLOOXYGENASE+2 Search CYCLOOXYGENASE+2
4 NON STEROIDAL ANTI INFLAMMATORY DRUGS 182255 2% 29% 892 Search NON+STEROIDAL+ANTI+INFLAMMATORY+DRUGS Search NON+STEROIDAL+ANTI+INFLAMMATORY+DRUGS
5 LIPOXYGENASE 177826 2% 35% 728 Search LIPOXYGENASE Search LIPOXYGENASE
6 COX 2 177596 2% 28% 901 Search COX+2 Search COX+2
7 CELECOXIB 173828 1% 42% 592 Search CELECOXIB Search CELECOXIB
8 EPOXYEICOSATRIENOIC ACIDS 171857 1% 80% 306 Search EPOXYEICOSATRIENOIC+ACIDS Search EPOXYEICOSATRIENOIC+ACIDS
9 LEUKOTRIENES 170644 2% 36% 671 Search LEUKOTRIENES Search LEUKOTRIENES
10 COX 2 INHIBITORS 133784 1% 55% 347 Search COX+2+INHIBITORS Search COX+2+INHIBITORS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HAEGGSTROM, JZ , FUNK, CD , (2011) LIPOXYGENASE AND LEUKOTRIENE PATHWAYS: BIOCHEMISTRY, BIOLOGY, AND ROLES IN DISEASE.CHEMICAL REVIEWS. VOL. 111. ISSUE 10. P. 5866 -5898 359 81% 196
2 WOODWARD, DF , JONES, RL , NARUMIYA, S , (2011) INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY. LXXXIII: CLASSIFICATION OF PROSTANOID RECEPTORS, UPDATING 15 YEARS OF PROGRESS.PHARMACOLOGICAL REVIEWS. VOL. 63. ISSUE 3. P. 471 -538 529 59% 146
3 NAKAMURA, M , SHIMIZU, T , (2011) LEUKOTRIENE RECEPTORS.CHEMICAL REVIEWS. VOL. 111. ISSUE 10. P. 6231 -6298 554 71% 23
4 CAPRA, V , BACK, M , BARBIERI, SS , CAMERA, M , TREMOLI, E , ROVATI, GE , (2013) EICOSANOIDS AND THEIR DRUGS IN CARDIOVASCULAR DISEASES: FOCUS ON ATHEROSCLEROSIS AND STROKE.MEDICINAL RESEARCH REVIEWS. VOL. 33. ISSUE 2. P. 364-438 446 69% 18
5 IMIG, JD , (2012) EPOXIDES AND SOLUBLE EPOXIDE HYDROLASE IN CARDIOVASCULAR PHYSIOLOGY.PHYSIOLOGICAL REVIEWS. VOL. 92. ISSUE 1. P. 101-130 278 86% 114
6 BACK, M , DAHLEN, SE , DRAZEN, JM , EVANS, JF , SERHAN, CN , SHIMIZU, T , YOKOMIZO, T , ROVATI, GE , (2011) INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY. LXXXIV: LEUKOTRIENE RECEPTOR NOMENCLATURE, DISTRIBUTION, AND PATHOPHYSIOLOGICAL FUNCTIONS.PHARMACOLOGICAL REVIEWS. VOL. 63. ISSUE 3. P. 539-584 427 67% 37
7 KUHN, H , BANTHIYA, S , VAN LEYEN, K , (2015) MAMMALIAN LIPOXYGENASES AND THEIR BIOLOGICAL RELEVANCE.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1851. ISSUE 4. P. 308 -330 270 69% 39
8 SIMMONS, DL , BOTTING, RM , HLA, T , (2004) CYCLOOXYGENASE ISOZYMES: THE BIOLOGY OF PROSTAGLANDIN SYNTHESIS AND INHIBITION.PHARMACOLOGICAL REVIEWS. VOL. 56. ISSUE 3. P. 387-437 293 66% 742
9 ROMAN, RJ , (2002) P-450 METABOLITES OF ARACHIDONIC ACID IN THE CONTROL OF CARDIOVASCULAR FUNCTION.PHYSIOLOGICAL REVIEWS. VOL. 82. ISSUE 1. P. 131 -185 294 61% 792
10 BASIL, MC , LEVY, BD , (2016) SPECIALIZED PRO-RESOLVING MEDIATORS: ENDOGENOUS REGULATORS OF INFECTION AND INFLAMMATION.NATURE REVIEWS IMMUNOLOGY. VOL. 16. ISSUE 1. P. 51 -67 148 77% 19

Classes with closest relation at Level 3


Rank Class id link
1 429 SPHINGOSINE 1 PHOSPHATE//CERAMIDE//SPHINGOLIPIDS
2 535 TAURINE//CHRONIC GRANULOMATOUS DISEASE//L FORMS
3 261 HELICOBACTER PYLORI//GASTROENTEROLOGY & HEPATOLOGY//HELICOBACTER
4 387 DOCOSAHEXAENOIC ACID//CONJUGATED LINOLEIC ACID//FISH OIL
5 343 NITRIC OXIDE//PEROXYNITRITE//NITRIC OXIDE SYNTHASE
6 315 ALLERGY//MAST CELLS//BRADYKININ
7 230 P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA
8 285 ERDOSTEINE//PEROXIREDOXIN//GLUTATHIONE
9 54 ASTHMA//RESPIRATORY SYSTEM//ALLERGY
10 662 ANNEXIN//S100A4//S100A9

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