Class information for:
Level 2: EPOXYEICOSATRIENOIC ACIDS//LIPOXYGENASE//LEUKOTRIENES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
566 14430 38.4 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
275 3       NSAIDS//CYCLOOXYGENASE//CYCLOOXYGENASE 2 43399
566 2             EPOXYEICOSATRIENOIC ACIDS//LIPOXYGENASE//LEUKOTRIENES 14430
822 1                   PROSTAGLANDINS//ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH//BAY U9773 3033
1822 1                   LIPOXYGENASE//HYDROPEROXIDE LYASE//15 LIPOXYGENASE 2472
2000 1                   EPOXYEICOSATRIENOIC ACIDS//SOLUBLE EPOXIDE HYDROLASE//20 HYDROXYEICOSATETRAENOIC ACID 2392
3852 1                   5 LIPOXYGENASE//LEUKOTRIENES//5 LIPOXYGENASE ACTIVATING PROTEIN 1895
6315 1                   MONTELUKAST//LEUKOTRIENE RECEPTOR ANTAGONIST//CYSTEINYL LEUKOTRIENES 1501
8131 1                   EXPT THER EUT REPERFUS INJURY//RESOLVINS//LIPOXINS 1289
17640 1                   12S HETE//LY293111//ZYFLAMEND 589
19105 1                   3 HYDROXY OXYLIPINS//EICOSANOID//OLEATE HYDRATASE 522
21584 1                   13 OXOOCTADECADIENOIC ACID//13 HODE//HYDROXY OCTADECADIENOIC ACID 413
24065 1                   5 OXO ETE//HEPOXILIN A3//CLAUDE PEPPER 324

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPOXYEICOSATRIENOIC ACIDS authKW 511342 2% 80% 304
2 LIPOXYGENASE authKW 491441 5% 33% 696
3 LEUKOTRIENES authKW 438948 4% 34% 619
4 SOLUBLE EPOXIDE HYDROLASE authKW 400156 2% 86% 221
5 5 LIPOXYGENASE authKW 288333 2% 42% 327
6 EXPT THER EUT REPERFUS INJURY address 285727 2% 56% 242
7 MONTELUKAST authKW 255068 2% 44% 273
8 LIPOXINS authKW 250802 1% 71% 167
9 EICOSANOIDS authKW 215533 3% 22% 467
10 RESOLVINS authKW 212379 1% 80% 126

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 20163 33% 0% 4801
2 Pharmacology & Pharmacy 11049 18% 0% 2622
3 Allergy 8019 4% 1% 530
4 Biophysics 5863 8% 0% 1197
5 Cell Biology 5248 12% 0% 1672
6 Respiratory System 3763 5% 0% 690
7 Immunology 3407 9% 0% 1317
8 Endocrinology & Metabolism 2917 7% 0% 965
9 Chemistry, Medicinal 2210 4% 0% 638
10 Physiology 2016 5% 0% 731

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EXPT THER EUT REPERFUS INJURY 285727 2% 56% 242
2 EICOSANOID 65767 0% 84% 37
3 CHEM 2 53261 0% 43% 59
4 ANESTHESIOL PERIOPERAT PAIN MED 49533 1% 13% 186
5 PHYSIOL CHEM 2 42735 1% 27% 76
6 CLAUDE PEPPER 33450 0% 41% 39
7 MED BIOCHEM BIOPHYS 23156 1% 6% 191
8 CARDIOPULM PHARMACOL 23111 0% 58% 19
9 UCD CANC 21748 0% 47% 22
10 SW MED MOLEC GENET 20609 0% 51% 19

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH 143348 2% 29% 232
2 PROSTAGLANDINS & OTHER LIPID MEDIATORS 91457 2% 16% 280
3 PROSTAGLANDINS 69963 2% 15% 221
4 PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 33382 2% 7% 223
5 PROSTAGLANDINS LEUKOTRIENES AND MEDICINE 13454 1% 9% 75
6 EICOSANOIDS 9943 0% 20% 24
7 JOURNAL OF LIPID MEDIATORS 8375 0% 12% 33
8 BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM 6748 0% 5% 59
9 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 5810 1% 3% 87
10 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 5762 2% 1% 248

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EPOXYEICOSATRIENOIC ACIDS 511342 2% 80% 304 Search EPOXYEICOSATRIENOIC+ACIDS Search EPOXYEICOSATRIENOIC+ACIDS
2 LIPOXYGENASE 491441 5% 33% 696 Search LIPOXYGENASE Search LIPOXYGENASE
3 LEUKOTRIENES 438948 4% 34% 619 Search LEUKOTRIENES Search LEUKOTRIENES
4 SOLUBLE EPOXIDE HYDROLASE 400156 2% 86% 221 Search SOLUBLE+EPOXIDE+HYDROLASE Search SOLUBLE+EPOXIDE+HYDROLASE
5 5 LIPOXYGENASE 288333 2% 42% 327 Search 5+LIPOXYGENASE Search 5+LIPOXYGENASE
6 MONTELUKAST 255068 2% 44% 273 Search MONTELUKAST Search MONTELUKAST
7 LIPOXINS 250802 1% 71% 167 Search LIPOXINS Search LIPOXINS
8 EICOSANOIDS 215533 3% 22% 467 Search EICOSANOIDS Search EICOSANOIDS
9 RESOLVINS 212379 1% 80% 126 Search RESOLVINS Search RESOLVINS
10 CYSTEINYL LEUKOTRIENES 195789 1% 52% 177 Search CYSTEINYL+LEUKOTRIENES Search CYSTEINYL+LEUKOTRIENES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HAEGGSTROM, JZ , FUNK, CD , (2011) LIPOXYGENASE AND LEUKOTRIENE PATHWAYS: BIOCHEMISTRY, BIOLOGY, AND ROLES IN DISEASE.CHEMICAL REVIEWS. VOL. 111. ISSUE 10. P. 5866 -5898 355 80% 196
2 NAKAMURA, M , SHIMIZU, T , (2011) LEUKOTRIENE RECEPTORS.CHEMICAL REVIEWS. VOL. 111. ISSUE 10. P. 6231 -6298 540 70% 23
3 IMIG, JD , (2012) EPOXIDES AND SOLUBLE EPOXIDE HYDROLASE IN CARDIOVASCULAR PHYSIOLOGY.PHYSIOLOGICAL REVIEWS. VOL. 92. ISSUE 1. P. 101-130 275 85% 114
4 BACK, M , DAHLEN, SE , DRAZEN, JM , EVANS, JF , SERHAN, CN , SHIMIZU, T , YOKOMIZO, T , ROVATI, GE , (2011) INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY. LXXXIV: LEUKOTRIENE RECEPTOR NOMENCLATURE, DISTRIBUTION, AND PATHOPHYSIOLOGICAL FUNCTIONS.PHARMACOLOGICAL REVIEWS. VOL. 63. ISSUE 3. P. 539-584 424 67% 37
5 KUHN, H , BANTHIYA, S , VAN LEYEN, K , (2015) MAMMALIAN LIPOXYGENASES AND THEIR BIOLOGICAL RELEVANCE.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1851. ISSUE 4. P. 308 -330 268 69% 39
6 ROMAN, RJ , (2002) P-450 METABOLITES OF ARACHIDONIC ACID IN THE CONTROL OF CARDIOVASCULAR FUNCTION.PHYSIOLOGICAL REVIEWS. VOL. 82. ISSUE 1. P. 131 -185 293 61% 792
7 BASIL, MC , LEVY, BD , (2016) SPECIALIZED PRO-RESOLVING MEDIATORS: ENDOGENOUS REGULATORS OF INFECTION AND INFLAMMATION.NATURE REVIEWS IMMUNOLOGY. VOL. 16. ISSUE 1. P. 51 -67 148 77% 19
8 BRINK, C , DAHLEN, SE , DRAZEN, J , EVANS, JF , HAY, DWP , NICOSIA, S , SERHAN, CN , SHIMIZU, T , YOKOMIZO, T , (2003) INTERNATIONAL UNION OF PHARMACOLOGY - XXXVII. NOMENCLATURE FOR LEUKOTRIENE AND LIPOXIN RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 55. ISSUE 1. P. 195 -227 295 85% 182
9 SERHAN, CN , (2014) PRO-RESOLVING LIPID MEDIATORS ARE LEADS FOR RESOLUTION PHYSIOLOGY.NATURE. VOL. 510. ISSUE 7503. P. 92 -101 99 88% 267
10 WESTPHAL, C , KONKEL, A , SCHUNCK, WH , (2015) CYTOCHROME P450 ENZYMES IN THE BIOACTIVATION OF POLYUNSATURATED FATTY ACIDS AND THEIR ROLE IN CARDIOVASCULAR DISEASE.MONOOXYGENASE, PEROXIDASE AND PEROXYGENASE PROPERTIES AND MECHANISMS OF CYTOCHROME P450. VOL. 851. ISSUE . P. 151 -187 232 83% 4

Classes with closest relation at Level 2


Rank Class id link
1 1311 PROSTAGLANDIN D 2//CRTH2//MOL BEHAV BIOL
2 3536 EVOLUTIONARY IMMUNOBIOL//PERITONEAL INFLAMMATION//ZYMOSAN
3 3141 EPOXIDE HYDROLASE//HALOALKANE DEHALOGENASE//DEHALOGENASE
4 2112 PLATELET ACTIVATING FACTOR//LIPOPROTEIN ASSOCIATED PHOSPHOLIPASE A2//PAF
5 112 ASTHMA//EOSINOPHILS//ALLERGY
6 2108 PULMONARY INTRAVASCULAR MACROPHAGES//ACUTE LUNG INJURY//CIRCULATORY SHOCK
7 1114 PHOSPHOLIPASE A2//PLASMALOGEN//LIPIDOMICS
8 1301 CHRONIC GRANULOMATOUS DISEASE//FORMYL PEPTIDE RECEPTOR//NADPH OXIDASE
9 2305 CYCLOOXYGENASE 2//COX 2//CELECOXIB
10 296 DOCOSAHEXAENOIC ACID//FISH OIL//EICOSAPENTAENOIC ACID

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