Class information for:
Level 2: CALPAIN//CALPASTATIN//CALPAIN INHIBITOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2896 2802 41.2 79%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
180 3       DUCHENNE MUSCULAR DYSTROPHY//DYSTROPHIN//MUSCULAR DYSTROPHY 56784
2896 2             CALPAIN//CALPASTATIN//CALPAIN INHIBITOR 2802
1530 1                   CALPAIN//CALPASTATIN//CALPAIN INHIBITOR 2610
35227 1                   DYSTROPHIN DYS//GENE TRANSFECTION IN VIVO//INTERNAL MED ORGANOL PATHOL CARDIOVASC 100
35753 1                   NA DEPENDENT CA2 UPTAKE//TISSUE INHIBITOR OF METALLOPROTEASE 2//GIALPHA 92

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CALPAIN authKW 3552575 32% 37% 884
2 CALPASTATIN authKW 1395255 9% 54% 239
3 CALPAIN INHIBITOR authKW 523059 3% 68% 71
4 M CALPAIN authKW 291945 2% 62% 43
5 CALPAIN PROJECT address 190169 1% 73% 24
6 ADV SCI BIOMOL address 116733 1% 71% 15
7 P94 authKW 109865 0% 92% 11
8 SENJU OCULAR SCI address 100837 1% 49% 19
9 LP82 authKW 88255 0% 90% 9
10 CALPAIN II authKW 83810 0% 77% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 9266 48% 0% 1351
2 Biophysics 3818 14% 0% 397
3 Neurosciences 2375 19% 0% 529
4 Cell Biology 2245 16% 0% 450
5 Ophthalmology 219 3% 0% 85
6 Chemistry, Medicinal 156 3% 0% 84
7 Peripheral Vascular Diseases 150 3% 0% 82
8 Physiology 122 3% 0% 93
9 Hematology 75 2% 0% 68
10 Cardiac & Cardiovascular System 68 3% 0% 93

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CALPAIN PROJECT 190169 1% 73% 24
2 ADV SCI BIOMOL 116733 1% 71% 15
3 SENJU OCULAR SCI 100837 1% 49% 19
4 ORAL MOL BIOL OPHTHALMOL 77480 0% 89% 8
5 BIOL FUNCTBUNKYO KU 59319 0% 78% 7
6 PROTEOLYT NEUROSCI 58671 1% 18% 30
7 MOL CELLULAR REGULATCHIKUSA KU 48531 0% 64% 7
8 DENT OPHTHALMOL 43583 0% 100% 4
9 ENZYMAT REGULAT CELL FUNCT 35586 0% 47% 7
10 ISTAB USC 32688 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOCHEMISTRY 3684 2% 1% 61
2 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2503 5% 0% 129
3 JOURNAL OF NEUROSCIENCE RESEARCH 2229 2% 0% 43
4 JOURNAL OF BIOLOGICAL CHEMISTRY 2153 7% 0% 183
5 BIOLOGICAL CHEMISTRY 2085 1% 1% 25
6 JOURNAL OF NEUROCHEMISTRY 1848 2% 0% 61
7 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1781 2% 0% 54
8 NEUROCHEMICAL RESEARCH 1573 1% 0% 33
9 FEBS LETTERS 1509 3% 0% 78
10 BIOCHEMICAL JOURNAL 1203 2% 0% 59

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CALPAIN 3552575 32% 37% 884 Search CALPAIN Search CALPAIN
2 CALPASTATIN 1395255 9% 54% 239 Search CALPASTATIN Search CALPASTATIN
3 CALPAIN INHIBITOR 523059 3% 68% 71 Search CALPAIN+INHIBITOR Search CALPAIN+INHIBITOR
4 M CALPAIN 291945 2% 62% 43 Search M+CALPAIN Search M+CALPAIN
5 P94 109865 0% 92% 11 Search P94 Search P94
6 LP82 88255 0% 90% 9 Search LP82 Search LP82
7 CALPAIN II 83810 0% 77% 10 Search CALPAIN+II Search CALPAIN+II
8 CALPAIN INHIBITION 83810 0% 77% 10 Search CALPAIN+INHIBITION Search CALPAIN+INHIBITION
9 MU CALPAIN 80081 1% 29% 25 Search MU+CALPAIN Search MU+CALPAIN
10 CALPAIN 2 73644 0% 52% 13 Search CALPAIN+2 Search CALPAIN+2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GOLL, DE , THOMPSON, VF , LI, HQ , WEI, W , CONG, JY , (2003) THE CALPAIN SYSTEM.PHYSIOLOGICAL REVIEWS. VOL. 83. ISSUE 3. P. 731 -801 345 77% 1533
2 PIETSCH, M , CHUA, KCH , ABELL, AD , (2010) CALPAINS: ATTRACTIVE TARGETS FOR THE DEVELOPMENT OF SYNTHETIC INHIBITORS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 3. P. 270-293 219 78% 37
3 STORR, SJ , CARRAGHER, NO , FRAME, MC , PARR, T , MARTIN, SG , (2011) THE CALPAIN SYSTEM AND CANCER.NATURE REVIEWS CANCER. VOL. 11. ISSUE 5. P. 364 -374 136 71% 130
4 CROALL, DE , DEMARTINO, GN , (1991) CALCIUM-ACTIVATED NEUTRAL PROTEASE (CALPAIN) SYSTEM - STRUCTURE, FUNCTION, AND REGULATION.PHYSIOLOGICAL REVIEWS. VOL. 71. ISSUE 3. P. 813-847 216 62% 739
5 CARRAGHER, NO , (2006) CALPAIN INHIBITION: A THERAPEUTIC STRATEGY TARGETING MULTIPLE DISEASE STATES.CURRENT PHARMACEUTICAL DESIGN. VOL. 12. ISSUE 5. P. 615-638 165 74% 101
6 CAMPBELL, RL , DAVIES, PL , (2012) STRUCTURE-FUNCTION RELATIONSHIPS IN CALPAINS.BIOCHEMICAL JOURNAL. VOL. 447. ISSUE . P. 335 -351 95 87% 60
7 FRANCO, SJ , HUTTENLOCHER, A , (2005) REGULATING CELL MIGRATION: CALPAINS MAKE THE CUT.JOURNAL OF CELL SCIENCE. VOL. 118. ISSUE 17. P. 3829-3838 109 79% 268
8 DONKOR, IO , (2011) CALPAIN INHIBITORS: A SURVEY OF COMPOUNDS REPORTED IN THE PATENT AND SCIENTIFIC LITERATURE.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 21. ISSUE 5. P. 601 -636 97 84% 33
9 ONO, Y , SAIDO, TC , SORIMACHI, H , (2016) CALPAIN RESEARCH FOR DRUG DISCOVERY: CHALLENGES AND POTENTIAL.NATURE REVIEWS DRUG DISCOVERY. VOL. 15. ISSUE 12. P. 854 -876 147 53% 0
10 ONO, Y , OJIMA, K , SHINKAI-OUCHI, F , HATA, S , SORIMACHI, H , (2016) AN ECCENTRIC CALPAIN, CAPN3/P94/CALPAIN-3.BIOCHIMIE. VOL. 122. ISSUE . P. 169 -187 131 55% 1

Classes with closest relation at Level 2


Rank Class id link
1 1744 CATHEPSIN//CATHEPSIN K//CATHEPSIN B
2 990 LENS//CATARACT//ALPHA CRYSTALLIN
3 991 DUCHENNE MUSCULAR DYSTROPHY//DYSTROPHIN//MUSCULAR DYSTROPHY
4 1486 PROTEIN KINASE C//BRYOSTATIN//BRYOSTATIN 1
5 3707 PARALYSIS//MOXISYLYTE//MEMBRANE SEALING
6 1245 ERYPTOSIS//BAND 3//HEREDITARY SPHEROCYTOSIS
7 1857 TITIN//INCLUSION BODY MYOSITIS//NEMALINE MYOPATHY
8 3019 CLENBUTEROL//RACTOPAMINE//BETA AGONISTS
9 359 CEREBRAL ISCHEMIA//SPREADING DEPRESSION//JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
10 411 MEAT SCIENCE//BEEF//TENDERNESS

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