Class information for:
Level 2: SIGLEC//TREM2//TREM 1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2906 2784 42.6 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
350 3       COMPLEMENT//MANNOSE BINDING LECTIN//IMMUNOLOGY 35656
2906 2             SIGLEC//TREM2//TREM 1 2784
12766 1                   SIGLEC//CD22//SIALOADHESIN 882
14945 1                   TREM2//TREM 1//NASU HAKOLA DISEASE 740
16383 1                   LAIR 1//CD300A//ITIM 656
22899 1                   CD200//CD200R//RP105 365
32315 1                   FCRL3//FCRL//FCRL3 GENE 141

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SIGLEC authKW 876048 4% 74% 108
2 TREM2 authKW 824472 3% 85% 88
3 TREM 1 authKW 629021 2% 83% 69
4 CD200 authKW 624859 3% 64% 89
5 NASU HAKOLA DISEASE authKW 328990 1% 100% 30
6 CD22 authKW 316348 2% 42% 69
7 DAP12 authKW 272425 2% 59% 42
8 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 authKW 224633 1% 79% 26
9 MEMBRANOUS LIPODYSTROPHY authKW 219823 1% 95% 21
10 STREM 1 authKW 219570 1% 69% 29

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Immunology 23345 44% 0% 1225
2 Biochemistry & Molecular Biology 851 18% 0% 515
3 Hematology 655 5% 0% 152
4 Cell Biology 610 10% 0% 265
5 Medicine, Research & Experimental 470 6% 0% 167
6 Neurosciences 439 10% 0% 274
7 Rheumatology 348 2% 0% 65
8 Pathology 346 4% 0% 107
9 Transplantation 138 2% 0% 52
10 Critical Care Medicine 136 2% 0% 48

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 WELLCOME TRUST BIO DUNDEE 77981 0% 89% 8
2 WELLCOME TRUST BIO 66582 2% 11% 53
3 GLYCOBIOL TRAINING 63717 1% 14% 41
4 DEV CLIN IMMUNOL 54713 1% 18% 27
5 SERV TR IANTI ORGANO 47668 0% 43% 10
6 RECEPTOR CELL BIOL SECT 45712 1% 30% 14
7 PHYSIOL EXPT 32899 0% 100% 3
8 BIOCHEM HEIDELBERG 30458 0% 56% 5
9 NEURAL REGENERAT GRP 28192 0% 43% 6
10 MOL DEV IMMUNOL 26112 0% 26% 9

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF IMMUNOLOGY 9515 8% 0% 218
2 EUROPEAN JOURNAL OF IMMUNOLOGY 5774 3% 1% 84
3 IMMUNOGENETICS 4275 2% 1% 42
4 HUMAN IMMUNOLOGY 3538 1% 1% 39
5 JOURNAL OF EXPERIMENTAL MEDICINE 2719 2% 0% 56
6 INTERNATIONAL IMMUNOLOGY 2573 1% 1% 31
7 GLYCOBIOLOGY 2565 1% 1% 26
8 NATURE IMMUNOLOGY 2367 1% 1% 22
9 DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 2359 1% 1% 28
10 IMMUNITY 2118 1% 1% 26

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SIGLEC 876048 4% 74% 108 Search SIGLEC Search SIGLEC
2 TREM2 824472 3% 85% 88 Search TREM2 Search TREM2
3 TREM 1 629021 2% 83% 69 Search TREM+1 Search TREM+1
4 CD200 624859 3% 64% 89 Search CD200 Search CD200
5 NASU HAKOLA DISEASE 328990 1% 100% 30 Search NASU+HAKOLA+DISEASE Search NASU+HAKOLA+DISEASE
6 CD22 316348 2% 42% 69 Search CD22 Search CD22
7 DAP12 272425 2% 59% 42 Search DAP12 Search DAP12
8 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 224633 1% 79% 26 Search TRIGGERING+RECEPTOR+EXPRESSED+ON+MYELOID+CELLS+1 Search TRIGGERING+RECEPTOR+EXPRESSED+ON+MYELOID+CELLS+1
9 MEMBRANOUS LIPODYSTROPHY 219823 1% 95% 21 Search MEMBRANOUS+LIPODYSTROPHY Search MEMBRANOUS+LIPODYSTROPHY
10 STREM 1 219570 1% 69% 29 Search STREM+1 Search STREM+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VARKI, A , ANGATA, T , (2006) SIGLECS - THE MAJOR SUBFAMILY OF I-TYPE LECTINS.GLYCOBIOLOGY. VOL. 16. ISSUE 1. P. 1R-27R 177 75% 187
2 CROCKER, PR , PAULSON, JC , VARKI, A , (2007) SIGLECS AND THEIR ROLES IN THE IMMUNE SYSTEM.NATURE REVIEWS IMMUNOLOGY. VOL. 7. ISSUE 4. P. 255-266 99 81% 591
3 MACAULEY, MS , CROCKER, PR , PAULSON, JC , (2014) SIGLEC-MEDIATED REGULATION OF IMMUNE CELL FUNCTION IN DISEASE.NATURE REVIEWS IMMUNOLOGY. VOL. 14. ISSUE 10. P. 653 -666 100 72% 76
4 PILLAI, S , NETRAVALI, IA , CARIAPPA, A , MATTOO, H , (2012) SIGLECS AND IMMUNE REGULATION.ANNUAL REVIEW OF IMMUNOLOGY, VOL 30. VOL. 30. ISSUE . P. 357 -392 117 73% 93
5 BOSCO, MC , RAGGI, F , VARESIO, L , (2016) THERAPEUTIC POTENTIAL OF TARGETING TREM-1 IN INFLAMMATORY DISEASES AND CANCER.CURRENT PHARMACEUTICAL DESIGN. VOL. 22. ISSUE 41. P. 6209 -6233 136 66% 1
6 PAULSON, JC , MACAULEY, MS , KAWASAKI, N , (2012) SIGLECS AS SENSORS OF SELF IN INNATE AND ADAPTIVE IMMUNE RESPONSES.GLYCOBIOLOGY OF THE IMMUNE RESPONSE. VOL. 1253. ISSUE . P. 37-48 101 78% 27
7 VON GUNTEN, S , BOCHNER, BS , (2008) BASIC AND CLINICAL IMMUNOLOGY OF SIGLECS.YEAR IN IMMUNOLOGY 2008. VOL. 1143. ISSUE . P. 61-82 107 71% 53
8 KANG, XL , KIM, J , DENG, M , JOHN, S , CHEN, HY , WU, GJ , PHAN, H , ZHANG, CC , (2016) INHIBITORY LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTORS: IMMUNE CHECKPOINT PROTEINS AND TUMOR SUSTAINING FACTORS.CELL CYCLE. VOL. 15. ISSUE 1. P. 25 -40 104 57% 2
9 MAGESH, S , ANDO, H , TSUBATA, T , ISHIDA, H , KISO, M , (2011) HIGH-AFFINITY LIGANDS OF SIGLEC RECEPTORS AND THEIR THERAPEUTIC POTENTIALS.CURRENT MEDICINAL CHEMISTRY. VOL. 18. ISSUE 23. P. 3537-3550 97 75% 8
10 NITSCHKE, L , (2009) CD22 AND SIGLEC-G: B-CELL INHIBITORY RECEPTORS WITH DISTINCT FUNCTIONS.IMMUNOLOGICAL REVIEWS. VOL. 230. ISSUE . P. 128-143 84 74% 62

Classes with closest relation at Level 2


Rank Class id link
1 2797 FC RECEPTOR//FC GAMMA RECEPTORS//FC GAMMA RECEPTOR
2 2405 POLYSIALIC ACID//NCAM//NEURAL CELL ADHESION MOLECULE
3 328 NK CELLS//NATURAL KILLER CELLS//KIR
4 1367 DENDRITIC CELLS//DC SIGN//LANGERHANS CELLS
5 1832 HLA G//AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY//JOURNAL OF REPRODUCTIVE IMMUNOLOGY
6 1273 GANGLIOSIDES//SIALIC ACID//GLYCOSPHINGOLIPIDS
7 919 PD L1//PD 1//FOXP3
8 1470 OLIGODENDROCYTE//REMYELINATION//MYELIN
9 1574 TIGHT JUNCTION//NOONAN SYNDROME//CLAUDIN
10 3191 SECRETORY COMPONENT//POLYMERIC IMMUNOGLOBULIN RECEPTOR//CD89

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