Class information for:
Level 2: ENDOCRINE POLYPEPTIDE CANC//GHRH ANTAGONISTS//LHRH RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3005 2547 33.9 66%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
17 4 REPRODUCTIVE BIOLOGY//OBSTETRICS & GYNECOLOGY//VETERINARY SCIENCES 563730
132 3       REPRODUCTIVE BIOLOGY//FERTILITY AND STERILITY//OBSTETRICS & GYNECOLOGY 66807
3005 2             ENDOCRINE POLYPEPTIDE CANC//GHRH ANTAGONISTS//LHRH RECEPTOR 2547
10053 1                   WOMENS HOSP MAX PLANCK CLIN UNIT REPROD MED//ANIM SCI PROD GRP//1000 CARSON ST 1096
13740 1                   LHRH RECEPTOR//ENDOCRINE POLYPEPTIDE CANC//CYTOTOXIC LHRH ANALOG 816
21073 1                   EXPLORATORY DISCOVERY//LHRH ANTAGONIST//AZALINE B 434
28712 1                   ENDOCRINE POLYPEPTIDE CANC//GHRH ANTAGONISTS//GROWTH HORMONE RELEASING HORMONE ANTAGONIST 201

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENDOCRINE POLYPEPTIDE CANC address 1193572 6% 68% 147
2 GHRH ANTAGONISTS authKW 393379 1% 86% 38
3 LHRH RECEPTOR authKW 337962 1% 83% 34
4 SECT EXPT MED address 311842 2% 43% 61
5 LHRH ANTAGONIST authKW 241292 1% 54% 37
6 CYTOTOXIC LHRH ANALOG authKW 119869 0% 100% 10
7 GNRH RECEPTOR authKW 115965 2% 22% 44
8 GROWTH HORMONE RELEASING HORMONE ANTAGONIST authKW 108970 0% 91% 10
9 TARGETED CHEMOTHERAPY authKW 101208 1% 34% 25
10 AN 152 authKW 85239 0% 89% 8

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 15631 31% 0% 779
2 Reproductive Biology 4337 8% 0% 213
3 Obstetrics & Gynecology 2821 11% 0% 273
4 Andrology 2742 2% 0% 54
5 Oncology 2205 17% 0% 430
6 Urology & Nephrology 1000 6% 0% 165
7 Chemistry, Medicinal 994 7% 0% 167
8 Pharmacology & Pharmacy 670 12% 0% 303
9 Biochemistry & Molecular Biology 253 13% 0% 329
10 Medicine, Research & Experimental 138 4% 0% 101

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENDOCRINE POLYPEPTIDE CANC 1193572 6% 68% 147
2 SECT EXPT MED 311842 2% 43% 61
3 EXPLORATORY DISCOVERY 74682 0% 69% 9
4 POLYPEPTIDE CANC 59935 0% 100% 5
5 S FLORIDA VET AFFAIRS FDN EDUC 53938 0% 75% 6
6 ANALYT CHEM BIOPOLYMER STRUCT ANAL 41197 1% 25% 14
7 GEN HOSP OBERNDORF 33293 0% 56% 5
8 BIOTECHNOL INCUBATING GOLDEN HELIX 23974 0% 100% 2
9 MED MED SECT EXPT MED 23974 0% 100% 2
10 S FLORIDA VA FDN EDUC 23974 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERNATIONAL JOURNAL OF FERTILITY 12204 1% 4% 27
2 PROSTATE 7615 2% 1% 54
3 CONTRACEPTION 6840 2% 1% 53
4 ENDOCRINOLOGY 6477 5% 0% 117
5 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 4699 2% 1% 60
6 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 4339 4% 0% 94
7 JOURNAL OF ANDROLOGY 4294 1% 1% 31
8 MOLECULAR AND CELLULAR ENDOCRINOLOGY 2735 2% 1% 45
9 BIOLOGY OF REPRODUCTION 2526 2% 0% 51
10 FERTILITY AND STERILITY 2380 2% 0% 57

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GHRH ANTAGONISTS 393379 1% 86% 38 Search GHRH+ANTAGONISTS Search GHRH+ANTAGONISTS
2 LHRH RECEPTOR 337962 1% 83% 34 Search LHRH+RECEPTOR Search LHRH+RECEPTOR
3 LHRH ANTAGONIST 241292 1% 54% 37 Search LHRH+ANTAGONIST Search LHRH+ANTAGONIST
4 CYTOTOXIC LHRH ANALOG 119869 0% 100% 10 Search CYTOTOXIC+LHRH+ANALOG Search CYTOTOXIC+LHRH+ANALOG
5 GNRH RECEPTOR 115965 2% 22% 44 Search GNRH+RECEPTOR Search GNRH+RECEPTOR
6 GROWTH HORMONE RELEASING HORMONE ANTAGONIST 108970 0% 91% 10 Search GROWTH+HORMONE+RELEASING+HORMONE+ANTAGONIST Search GROWTH+HORMONE+RELEASING+HORMONE+ANTAGONIST
7 TARGETED CHEMOTHERAPY 101208 1% 34% 25 Search TARGETED+CHEMOTHERAPY Search TARGETED+CHEMOTHERAPY
8 AN 152 85239 0% 89% 8 Search AN+152 Search AN+152
9 TARGETED CANCER CHEMOTHERAPY 71922 0% 100% 6 Search TARGETED+CANCER+CHEMOTHERAPY Search TARGETED+CANCER+CHEMOTHERAPY
10 LH RH 69841 1% 45% 13 Search LH+RH Search LH+RH

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LIMONTA, P , MARELLI, MM , MAI, S , MOTTA, M , MARTINI, L , MORETTI, RM , (2012) GNRH RECEPTORS IN CANCER: FROM CELL BIOLOGY TO NOVEL TARGETED THERAPEUTIC STRATEGIES.ENDOCRINE REVIEWS. VOL. 33. ISSUE 5. P. 784 -811 148 56% 30
2 LIMONTA, P , MANEA, M , (2013) GONADOTROPIN-RELEASING HORMONE RECEPTORS AS MOLECULAR THERAPEUTIC TARGETS IN PROSTATE CANCER: CURRENT OPTIONS AND EMERGING STRATEGIES.CANCER TREATMENT REVIEWS. VOL. 39. ISSUE 6. P. 647 -663 121 51% 20
3 MIWA, K , HITAKA, T , IMADA, T , SASAKI, S , YOSHIMATSU, M , KUSAKA, M , TANAKA, A , NAKATA, D , FURUYA, S , ENDO, S , ET AL (2011) DISCOVERY OF 1-{4[1-(2,6-DIFLUOROBENZYL)-5-[(DIMETHYLAMINO)METHYL]-3-(6-METHOXYPYRIDAZIN-3-YL)-2,4-DIOXO-1,2,3,4-TETRAHYDROTHIENO[2,3-D]PYRIMIDIN-6-YL]PHENYL]-3-METHOXYUREA (TAK-385) AS A POTENT, ORALLY ACTIVE, NON-PEPTIDE ANTAGONIST OF THE HUMAN GONADOTROPIN-RELEASING HORMONE RECEPTOR.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 54. ISSUE 14. P. 4998 -5012 69 85% 8
4 NAGY, A , SCHALLY, AV , (2005) TARGETING OF CYTOTOXIC LUTEINIZING HORMONE-RELEASING HORMONE ANALOGS TO BREAST, OVARIAN, ENDOMETRIAL, AND PROSTATE CANCERS.BIOLOGY OF REPRODUCTION. VOL. 73. ISSUE 5. P. 851-859 68 86% 78
5 SO, WK , CHENG, JC , POON, SL , LEUNG, PCK , (2008) GONADOTROPIN-RELEASING HORMONE AND OVARIAN CANCER: A FUNCTIONAL AND MECHANISTIC OVERVIEW.FEBS JOURNAL. VOL. 275. ISSUE 22. P. 5496 -5511 81 70% 20
6 MARELLI, MM , MORETTI, RM , JANUSZKIEWICZ-CAULIER, J , MOTTA, M , LIMONTA, P , (2006) GONADOTROPIN-RELEASING HORMONE (GNRH) RECEPTORS IN TUMORS: A NEW RATIONALE FOR THE THERAPEUTICAL APPLICATION OF GNRH ANALOGS IN CANCER PATIENTS?.CURRENT CANCER DRUG TARGETS. VOL. 6. ISSUE 3. P. 257-269 90 62% 26
7 AGUILAR-ROJAS, A , HUERTA-REYES, M , (2009) HUMAN GONADOTROPIN-RELEASING HORMONE RECEPTOR-ACTIVATED CELLULAR FUNCTIONS AND SIGNALING PATHWAYS IN EXTRA-PITUITARY TISSUES AND CANCER CELLS (REVIEW).ONCOLOGY REPORTS. VOL. 22. ISSUE 5. P. 981 -990 83 60% 27
8 CHEUNG, LWT , WONG, AST , (2008) GONADOTROPIN-RELEASING HORMONE: GNRH RECEPTOR SIGNALING IN EXTRAPITUITARY TISSUES.FEBS JOURNAL. VOL. 275. ISSUE 22. P. 5479 -5495 83 57% 58
9 ENGEL, JB , TINNEBERG, HR , RICK, FG , BERKES, E , SCHALLY, AV , (2016) TARGETING OF PEPTIDE CYTOTOXINS TO LHRH RECEPTORS FOR TREATMENT OF CANCER.CURRENT DRUG TARGETS. VOL. 17. ISSUE 5. P. 488 -494 39 95% 0
10 RAMAKRISHNAPPA, N , RAJAMAHENDRAN, R , LIN, YM , LEUNG, PCK , (2005) GNRH IN NON-HYPOTHALAMIC REPRODUCTIVE TISSUES.ANIMAL REPRODUCTION SCIENCE. VOL. 88. ISSUE 1-2. P. 95-113 76 57% 78

Classes with closest relation at Level 2


Rank Class id link
1 2602 NEUROPEPTIDE FF//SEA LAMPREY//PROLACTIN RELEASING PEPTIDE
2 658 KISSPEPTIN//INHIBIN//ACTIVIN
3 534 ANDROGEN RECEPTOR//PROSTATE CANCER//CASTRATION RESISTANT PROSTATE CANCER
4 1096 SERTOLI CELLS//TESTIS//SPERMATOGONIAL STEM CELLS
5 772 GRANULOSA CELLS//CORPUS LUTEUM//REPRODUCTIVE BIOLOGY
6 2629 HYPOTHALAMIC HAMARTOMA//MENARCHE//GELASTIC SEIZURES
7 452 FERTILITY AND STERILITY//REPRODUCTIVE BIOLOGY//OBSTETRICS & GYNECOLOGY
8 2008 FSH RECEPTOR//FOLLICLE STIMULATING HORMONE RECEPTOR//HUMAN CHORIONIC GONADOTROPIN
9 1647 ABDOMINAL COMPARTMENT SYNDROME//SOMATOSTATIN RECEPTOR//SOMATOSTATIN
10 1337 ENDOMETRIOSIS//ENDOMETRIOMA//DEEP INFILTRATING ENDOMETRIOSIS

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