Class information for:
Level 2: PIM KINASE//PIM 1//PIM 2

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4146 532 45.6 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
373 3       ENDOGENOUS RETROVIRUS//VIROLOGY//JOURNAL OF VIROLOGY 32972
4146 2             PIM KINASE//PIM 1//PIM 2 532
18870 1                   PIM KINASE//PIM 1//PIM 2 532

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PIM KINASE authKW 2314342 9% 81% 50
2 PIM 1 authKW 1750976 12% 49% 62
3 PIM 2 authKW 1322406 5% 96% 24
4 PIM 1 KINASE authKW 1236980 5% 86% 25
5 PIM 3 authKW 1100506 4% 91% 21
6 PIM1 authKW 808306 5% 54% 26
7 PIM KINASE INHIBITOR authKW 351550 1% 88% 7
8 PIM 1 KINASE INHIBITORS authKW 344377 1% 100% 6
9 CANC MICROENVIRONM PROGRAM address 258280 1% 75% 6
10 SGI 1776 authKW 258280 1% 75% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 2199 34% 0% 181
2 Cell Biology 1014 23% 0% 125
3 Chemistry, Medicinal 993 13% 0% 71
4 Biochemistry & Molecular Biology 582 30% 0% 160
5 Hematology 453 10% 0% 51
6 Genetics & Heredity 109 7% 0% 39
7 Medicine, Research & Experimental 77 6% 0% 30
8 Chemistry, Organic 74 7% 0% 37
9 Biophysics 37 4% 0% 22
10 Immunology 23 5% 0% 27

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC MICROENVIRONM PROGRAM 258280 1% 75% 6
2 PANCREAS HEPATOBILIARY 114792 0% 100% 2
3 THER EUT PROT DISCOVERY 114792 0% 100% 2
4 MOL BIOREGULAT 83306 3% 10% 14
5 CANC SHANGHAI CANC 73792 1% 43% 3
6 ABO AKAD UNIV 68584 1% 17% 7
7 AG HARTMANN 57396 0% 100% 1
8 CAN RELATED GENES 57396 0% 100% 1
9 CELL MOL BIOL CORE IL 57396 0% 100% 1
10 CHAIR CLIN HEMATOL NEOPLAST BLOOD DIS TRANSPL 57396 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOGENE 1653 4% 0% 23
2 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 1627 5% 0% 27
3 ONCOGENE RESEARCH 1301 0% 1% 2
4 ONCOTARGET 1031 3% 0% 15
5 BLOOD CANCER JOURNAL 774 0% 1% 2
6 MOLECULAR CANCER RESEARCH 760 1% 0% 5
7 BLOOD 707 4% 0% 21
8 MOLECULAR CANCER THERAPEUTICS 680 1% 0% 7
9 ACS MEDICINAL CHEMISTRY LETTERS 661 1% 0% 4
10 JOURNAL OF MEDICINAL CHEMISTRY 431 2% 0% 13

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PIM KINASE 2314342 9% 81% 50 Search PIM+KINASE Search PIM+KINASE
2 PIM 1 1750976 12% 49% 62 Search PIM+1 Search PIM+1
3 PIM 2 1322406 5% 96% 24 Search PIM+2 Search PIM+2
4 PIM 1 KINASE 1236980 5% 86% 25 Search PIM+1+KINASE Search PIM+1+KINASE
5 PIM 3 1100506 4% 91% 21 Search PIM+3 Search PIM+3
6 PIM1 808306 5% 54% 26 Search PIM1 Search PIM1
7 PIM KINASE INHIBITOR 351550 1% 88% 7 Search PIM+KINASE+INHIBITOR Search PIM+KINASE+INHIBITOR
8 PIM 1 KINASE INHIBITORS 344377 1% 100% 6 Search PIM+1+KINASE+INHIBITORS Search PIM+1+KINASE+INHIBITORS
9 SGI 1776 258280 1% 75% 6 Search SGI+1776 Search SGI+1776
10 PIM KINASE INHIBITION 239149 1% 83% 5 Search PIM+KINASE+INHIBITION Search PIM+KINASE+INHIBITION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 NARLIK-GRASSOW, M , BLANCO-APARICIO, C , CARNERO, A , (2014) THE PIM FAMILY OF SERINE/THREONINE KINASES IN CANCER.MEDICINAL RESEARCH REVIEWS. VOL. 34. ISSUE 1. P. 136-159 126 81% 40
2 BLANCO-APARICIO, C , CARNERO, A , (2013) PIM KINASES IN CANCER: DIAGNOSTIC, PROGNOSTIC AND TREATMENT OPPORTUNITIES.BIOCHEMICAL PHARMACOLOGY. VOL. 85. ISSUE 5. P. 629-643 118 84% 45
3 BRAULT, L , GASSER, C , BRACHER, F , HUBER, K , KNAPP, S , SCHWALLER, J , (2010) PIM SERINE/THREONINE KINASES IN THE PATHOGENESIS AND THERAPY OF HEMATOLOGIC MALIGNANCIES AND SOLID CANCERS.HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. VOL. 95. ISSUE 6. P. 1004 -1015 107 76% 137
4 LE, BT , KUMARASIRI, M , ADAMS, JRJ , YU, MF , MILNE, R , SYKES, MJ , WANG, SD , (2015) TARGETING PIM KINASES FOR CANCER TREATMENT: OPPORTUNITIES AND CHALLENGES.FUTURE MEDICINAL CHEMISTRY. VOL. 7. ISSUE 1. P. 35 -53 97 87% 4
5 NAWIJN, MC , ALENDAR, A , BERNS, A , (2011) FOR BETTER OR FOR WORSE: THE ROLE OF PIM ONCOGENES IN TUMORIGENESIS.NATURE REVIEWS CANCER. VOL. 11. ISSUE 1. P. 23 -34 102 60% 168
6 ALVARADO, Y , GILES, FJ , SWORDS, RT , (2012) THE PIM KINASES IN HEMATOLOGICAL CANCERS.EXPERT REVIEW OF HEMATOLOGY. VOL. 5. ISSUE 1. P. 81-96 105 67% 31
7 MERKEL, AL , MEGGERS, E , OCKER, M , (2012) PIM1 KINASE AS A TARGET FOR CANCER THERAPY.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 21. ISSUE 4. P. 425 -436 81 69% 45
8 WARFEL, NA , KRAFT, AS , (2015) PIM KINASE (AND AKT) BIOLOGY AND SIGNALING IN TUMORS.PHARMACOLOGY & THERAPEUTICS. VOL. 151. ISSUE . P. 41 -49 72 65% 17
9 LI, YY , MUKAIDA, N , (2014) PATHOPHYSIOLOGICAL ROLES OF PIM-3 KINASE IN PANCREATIC CANCER DEVELOPMENT AND PROGRESSION.WORLD JOURNAL OF GASTROENTEROLOGY. VOL. 20. ISSUE 28. P. 9392 -9404 78 73% 4
10 MAGNUSON, NS , WANG, ZP , DING, G , REEVES, R , (2010) WHY TARGET PIM1 FOR CANCER DIAGNOSIS AND TREATMENT?.FUTURE ONCOLOGY. VOL. 6. ISSUE 9. P. 1461-1478 94 61% 44

Classes with closest relation at Level 2


Rank Class id link
1 2754 MYC//MAX//C MYC
2 3177 PROTEIN KINASE CK2//CK2//CASEIN KINASE 2
3 4166 TCTP//TRANSLATIONALLY CONTROLLED TUMOR PROTEIN//TRANSLATIONALLY CONTROLLED TUMOR PROTEIN TCTP
4 1220 PTEN//MTOR//COWDEN SYNDROME
5 2874 CIP2A//PP2A//DEK
6 1269 JOURNAL OF CHEMICAL INFORMATION AND MODELING//LIFE SCI INFORMAT//B IT
7 1051 STAT3//GP130//ONCOSTATIN M
8 1632 EIF4E//TRANSLATION INITIATION//IRES
9 2228 C MYB//B MYB//SRC
10 3423 RNA EDITING//ADAR//AEG 1

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