Class information for:
Level 2: EIF4E//TRANSLATION INITIATION//IRES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1632 6984 47.4 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
153 3       BIOCHEMISTRY & MOLECULAR BIOLOGY//RIBOSOME//RNA 62593
1632 2             EIF4E//TRANSLATION INITIATION//IRES 6984
3885 1                   EIF4E//EIF4F//CAP ANALOG 1887
5844 1                   IRES//INTERNAL RIBOSOME ENTRY SITE//INTERNAL RIBOSOME ENTRY SITE IRES 1568
6259 1                   GENE REGULAT DEV//EIF3//EIF2 1507
9561 1                   PKR//NF90//VA RNA 1143
14173 1                   RIBOSOME PROFILING//UORF//UPSTREAM OPEN READING FRAME 787
35793 1                   RIBOTAG//S100A10//4SU 92

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EIF4E authKW 559935 3% 57% 223
2 TRANSLATION INITIATION authKW 529989 4% 41% 296
3 IRES authKW 502568 3% 55% 211
4 PKR authKW 406262 3% 50% 185
5 INITIATION FACTOR authKW 194827 1% 52% 85
6 GENE REGULAT DEV address 153338 2% 33% 107
7 EIF3 authKW 141940 1% 69% 47
8 TRANSLATION authKW 139112 6% 8% 401
9 INTERNAL RIBOSOME ENTRY SITE authKW 132129 1% 46% 66
10 EIF2 authKW 123405 1% 58% 49

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 38590 61% 0% 4240
2 Cell Biology 14903 25% 0% 1727
3 Virology 13099 11% 0% 755
4 Biophysics 2576 8% 0% 556
5 Genetics & Heredity 1571 8% 0% 531
6 Oncology 642 7% 0% 498
7 Biotechnology & Applied Microbiology 482 5% 0% 352
8 Developmental Biology 379 2% 0% 130
9 Biochemical Research Methods 330 3% 0% 229
10 Biology 160 2% 0% 146

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENE REGULAT DEV 153338 2% 33% 107
2 MCGILL CANC 76575 1% 21% 84
3 POSTTRANSCRIPT CONTROL GRP 48633 0% 70% 16
4 REGULAT GENE EXP S 38521 0% 42% 21
5 CELLULAR MOL SCI GRP 34954 0% 67% 12
6 TRANSLAT CONTROL GRP 33613 0% 77% 10
7 GRP BRAIN AGING 31098 0% 65% 11
8 UNITE REGULAT TRADUCT EUCARYOTE VIRALE 27966 0% 80% 8
9 EUKARYOT GENE REGULAT 27236 0% 20% 32
10 EQUIPE TRADUCT CYCLE CELLULAIRE DEV 25423 0% 73% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RNA 18836 2% 4% 105
2 MOLECULAR AND CELLULAR BIOLOGY 16476 4% 1% 293
3 RNA-A PUBLICATION OF THE RNA SOCIETY 14853 1% 5% 66
4 JOURNAL OF BIOLOGICAL CHEMISTRY 12439 10% 0% 677
5 NUCLEIC ACIDS RESEARCH 10949 5% 1% 321
6 JOURNAL OF VIROLOGY 9684 4% 1% 303
7 VIROLOGY 4447 2% 1% 141
8 EMBO JOURNAL 4106 2% 1% 130
9 GENES & DEVELOPMENT 2292 1% 1% 64
10 ONCOGENE 2249 1% 1% 100

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EIF4E 559935 3% 57% 223 Search EIF4E Search EIF4E
2 TRANSLATION INITIATION 529989 4% 41% 296 Search TRANSLATION+INITIATION Search TRANSLATION+INITIATION
3 IRES 502568 3% 55% 211 Search IRES Search IRES
4 PKR 406262 3% 50% 185 Search PKR Search PKR
5 INITIATION FACTOR 194827 1% 52% 85 Search INITIATION+FACTOR Search INITIATION+FACTOR
6 EIF3 141940 1% 69% 47 Search EIF3 Search EIF3
7 TRANSLATION 139112 6% 8% 401 Search TRANSLATION Search TRANSLATION
8 INTERNAL RIBOSOME ENTRY SITE 132129 1% 46% 66 Search INTERNAL+RIBOSOME+ENTRY+SITE Search INTERNAL+RIBOSOME+ENTRY+SITE
9 EIF2 123405 1% 58% 49 Search EIF2 Search EIF2
10 TRANSLATIONAL CONTROL 114881 2% 20% 135 Search TRANSLATIONAL+CONTROL Search TRANSLATIONAL+CONTROL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HINNEBUSCH, AG , (2014) THE SCANNING MECHANISM OF EUKARYOTIC TRANSLATION INITIATION.ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83. VOL. 83. ISSUE . P. 779 -812 174 76% 110
2 GINGRAS, AC , RAUGHT, B , SONENBERG, N , (1999) EIF4 INITIATION FACTORS: EFFECTORS OF MRNA RECRUITMENT TO RIBOSOMES AND REGULATORS OF TRANSLATION.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 68. ISSUE . P. 913 -963 214 63% 1331
3 PELLETIER, J , GRAFF, J , RUGGERO, D , SONENBERG, N , (2015) TARGETING THE EIF4F TRANSLATION INITIATION COMPLEX: A CRITICAL NEXUS FOR CANCER DEVELOPMENT.CANCER RESEARCH. VOL. 75. ISSUE 2. P. 250 -263 143 73% 33
4 HELLEN, CUT , SARNOW, P , (2001) INTERNAL RIBOSOME ENTRY SITES IN EUKARYOTIC MRNA MOLECULES.GENES & DEVELOPMENT. VOL. 15. ISSUE 13. P. 1593-1612 147 86% 617
5 DEVER, TE , KINZY, TG , PAVITT, GD , (2016) MECHANISM AND REGULATION OF PROTEIN SYNTHESIS IN SACCHAROMYCES CEREVISIAE.GENETICS. VOL. 203. ISSUE 1. P. 65 -107 261 57% 0
6 JOHNSON, AG , GROSELY, R , PETROV, AN , PUGLISI, JD , (2017) DYNAMICS OF IRES-MEDIATED TRANSLATION.PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. VOL. 372. ISSUE 1716. P. - 107 76% 1
7 CLEMENS, MJ , ELIA, A , (1997) THE DOUBLE-STRANDED RNA-DEPENDENT PROTEIN KINASE PKR: STRUCTURE AND FUNCTION.JOURNAL OF INTERFERON AND CYTOKINE RESEARCH. VOL. 17. ISSUE 9. P. 503-524 172 84% 416
8 VALASEK, LS , (2012) 'RIBOZOOMIN' - TRANSLATION INITIATION FROM THE PERSPECTIVE OF THE RIBOSOME-BOUND EUKARYOTIC INITIATION FACTORS (EIFS).CURRENT PROTEIN & PEPTIDE SCIENCE. VOL. 13. ISSUE 4. P. 305-330 162 77% 35
9 PAIN, VM , (1996) INITIATION OF PROTEIN SYNTHESIS IN EUKARYOTIC CELLS.EUROPEAN JOURNAL OF BIOCHEMISTRY. VOL. 236. ISSUE 3. P. 747 -771 212 62% 568
10 BAIRD, SD , TURCOTTE, M , KORNELUK, RG , HOLCIK, M , (2006) SEARCHING FOR IRES.RNA-A PUBLICATION OF THE RNA SOCIETY. VOL. 12. ISSUE 10. P. 1755-1785 200 64% 172

Classes with closest relation at Level 2


Rank Class id link
1 3078 ELONGATION FACTOR TU//ELONGATION FACTOR 2//EEF1A2
2 156 NUCLEAR PORE COMPLEX//PRE MRNA SPLICING//SPLICEOSOME
3 1220 PTEN//MTOR//COWDEN SYNDROME
4 3423 RNA EDITING//ADAR//AEG 1
5 745 FOOT AND MOUTH DISEASE//FOOT AND MOUTH DISEASE VIRUS//ENTEROVIRUS 71
6 1548 UNFOLDED PROTEIN RESPONSE//ENDOPLASMIC RETICULUM STRESS//ER STRESS
7 1297 RIBOSOME//TRANSLATION TERMINATION//TMRNA
8 4146 PIM KINASE//PIM 1//PIM 2
9 3425 YB 1//COLD SHOCK PROTEIN//Y BOX BINDING PROTEIN 1
10 3893 PRL 3//ATF3//ATF5

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