Class information for:
Level 1: INTERSPECIES SCALING//CLEARANCE PREDICTION//WELL STIRRED MODEL

Basic class information

Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes

The table includes all classes above and classes immediately below the current class.



Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
273 3       P GLYCOPROTEIN//MULTIDRUG RESISTANCE//DRUG METABOLISM AND DISPOSITION 43782
1763 2             JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//CACO 2//BIOPHARMACEUTICS & DRUG DISPOSITION 6737
10591 1                   INTERSPECIES SCALING//CLEARANCE PREDICTION//WELL STIRRED MODEL 1080

Terms with highest relevance score



rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 INTERSPECIES SCALING authKW 343078 3% 44% 27
2 CLEARANCE PREDICTION authKW 287305 1% 62% 16
3 WELL STIRRED MODEL authKW 259963 1% 64% 14
4 VOLUME OF DISTRIBUTION authKW 223736 3% 23% 33
5 COMPUTATIONAL ADME authKW 200771 2% 40% 17
6 INTRINSIC CLEARANCE authKW 198734 2% 36% 19
7 PL PHARMACOKINET address 181093 4% 16% 39
8 DMPK TRANSLAT SCI address 178730 1% 88% 7
9 IVIVE authKW 177432 1% 41% 15
10 STEADY STATE VOLUME OF DISTRIBUTION authKW 171643 1% 59% 10

Web of Science journal categories



chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Pharmacology & Pharmacy 23995 84% 0% 912
2 Chemistry, Medicinal 3348 17% 0% 183
3 Toxicology 2503 15% 0% 161
4 Chemistry, Multidisciplinary 737 19% 0% 207
5 Mathematical & Computational Biology 36 1% 0% 15
6 Computer Science, Interdisciplinary Applications 35 2% 0% 24
7 Medical Informatics 11 1% 0% 6
8 Medicine, Research & Experimental 4 2% 0% 22
9 Biochemical Research Methods 4 2% 0% 18
10 Medicine, Legal 3 0% 0% 3

Address terms



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 PL PHARMACOKINET 181093 4% 16% 39
2 DMPK TRANSLAT SCI 178730 1% 88% 7
3 WOODMONT OFF 2 143652 1% 62% 8
4 CLIN PHARMACOL TOXICOL BRANCH HFD 579 87542 0% 100% 3
5 THER EUT DRUGS FOOD ANIM HFV 130 87542 0% 100% 3
6 PHARMACOKINET DYNAM METAB 77582 5% 5% 49
7 DISCOVERY ADME TOX 72947 0% 50% 5
8 PHYS METAB SCI 64867 1% 17% 13
9 LOCAL DISCOVERY CNS PAIN 58361 0% 100% 2
10 METABOLISM PHARMACOKINET 58361 0% 100% 2

Journals



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 DRUG METABOLISM AND DISPOSITION 85413 14% 2% 149
2 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 54281 3% 5% 37
3 XENOBIOTICA 50846 8% 2% 83
4 JOURNAL OF PHARMACEUTICAL SCIENCES 38881 11% 1% 123
5 BIOPHARMACEUTICS & DRUG DISPOSITION 20509 3% 2% 37
6 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 19034 2% 3% 20
7 JOURNAL OF PHARMACOBIO-DYNAMICS 18303 3% 2% 32
8 PHARMACEUTICAL RESEARCH 9623 5% 1% 52
9 CURRENT DRUG METABOLISM 5740 1% 1% 15
10 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 5287 2% 1% 17

Author Key Words



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 INTERSPECIES SCALING 343078 3% 44% 27 Search INTERSPECIES+SCALING Search INTERSPECIES+SCALING
2 CLEARANCE PREDICTION 287305 1% 62% 16 Search CLEARANCE+PREDICTION Search CLEARANCE+PREDICTION
3 WELL STIRRED MODEL 259963 1% 64% 14 Search WELL+STIRRED+MODEL Search WELL+STIRRED+MODEL
4 VOLUME OF DISTRIBUTION 223736 3% 23% 33 Search VOLUME+OF+DISTRIBUTION Search VOLUME+OF+DISTRIBUTION
5 COMPUTATIONAL ADME 200771 2% 40% 17 Search COMPUTATIONAL+ADME Search COMPUTATIONAL+ADME
6 INTRINSIC CLEARANCE 198734 2% 36% 19 Search INTRINSIC+CLEARANCE Search INTRINSIC+CLEARANCE
7 IVIVE 177432 1% 41% 15 Search IVIVE Search IVIVE
8 STEADY STATE VOLUME OF DISTRIBUTION 171643 1% 59% 10 Search STEADY+STATE+VOLUME+OF+DISTRIBUTION Search STEADY+STATE+VOLUME+OF+DISTRIBUTION
9 HEPATIC CLEARANCE 157768 2% 21% 26 Search HEPATIC+CLEARANCE Search HEPATIC+CLEARANCE
10 PHYSIOLOGICALLY BASED PHARMACOKINETICS 152642 2% 28% 19 Search PHYSIOLOGICALLY+BASED+PHARMACOKINETICS Search PHYSIOLOGICALLY+BASED+PHARMACOKINETICS

Core articles

The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1



rank cluster_id2 link
1 9019 CYP2C8//COCKTAIL//MECHANISM BASED INHIBITION
2 11985 SECT PHARMACOKINET//JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//BOF 4272
3 38296 FRACTIONATED H 3HEPARIN//PHARMACEUT SCI BIOPHARMACEUT MIZUHO KU//RAT PARENCHYMAL HEPATOCYTE
4 3029 CACO 2//PAMPA//BIOPHARMACEUTICS CLASSIFICATION SYSTEM
5 4536 OATP1B1//SLCO1B1//PITAVASTATIN
6 8565 HIPPURIC ACID//PBPK MODELING//METHYLHIPPURIC ACID
7 17352 CNS 7056//CAS 76 75 5//CERTITUDE DIAGNOSIS
8 19382 PHARMACOKINET BIOANAL//MICROMINIPIG//MINIPIG
9 17381 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//DISPOSITION DECOMPOSITION ANALYSIS//FINITE DIFFERENCE DECONVOLUTION
10 19753 ALDEHYDE OXIDASE//HUMANIZED LIVER//RS 8359

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