Class information for:
Level 1: PIK3CA//PI3K INHIBITOR//PI3K

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
183 3       NOONAN SYNDROME//PTEN//CELL BIOLOGY 56293
1016 2             PTEN//MTOR//PI3K 10616
4527 1                   PIK3CA//PI3K INHIBITOR//PI3K 1801

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 PIK3CA authKW 1158745 10% 37% 177
2 PI3K INHIBITOR authKW 740966 4% 55% 77
3 PI3K authKW 497947 15% 11% 266
4 P110 ALPHA authKW 487142 2% 80% 35
5 PI3K ALPHA authKW 241338 1% 69% 20
6 PIK3CA MUTATION authKW 224170 2% 41% 31
7 P110 BETA authKW 203603 1% 73% 16
8 BEZ235 authKW 183707 1% 50% 21
9 ZSTK474 authKW 163304 1% 67% 14
10 NVP BEZ235 authKW 160738 1% 44% 21

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Oncology 20965 56% 0% 1003
2 Chemistry, Medicinal 2840 12% 0% 222
3 Cell Biology 1548 17% 0% 298
4 Biochemistry & Molecular Biology 463 17% 0% 312
5 Pathology 285 4% 0% 75
6 Chemistry, Organic 215 7% 0% 118
7 Pharmacology & Pharmacy 210 9% 0% 160
8 Genetics & Heredity 74 4% 0% 75
9 Hematology 53 2% 0% 45
10 Medicine, Research & Experimental 43 3% 0% 56

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 HIGH THROUGHPUT SCREENING MOL PHARMACOL 95263 0% 78% 7
2 CANC METAB DMPK 69992 0% 100% 4
3 ORIGINAL NEW DRUGS DESIGN DISCOVERY 67482 0% 43% 9
4 CANC METAB BIOL 55992 0% 80% 4
5 CANC METAB CHEM 55992 0% 80% 4
6 SMALL MOL TRANSLAT ONCOL 52494 0% 100% 3
7 ONCOL DIS AREA 51624 1% 27% 11
8 STRUCT BIOL MOL MODELING 39369 0% 75% 3
9 ONCOL BIOMARKER DEV 36486 1% 19% 11
10 BIOL ONCOL DRUG DISCOVERY 34996 0% 100% 2

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 MOLECULAR CANCER THERAPEUTICS 11195 3% 1% 52
2 CLINICAL CANCER RESEARCH 7596 5% 1% 82
3 ONCOTARGET 6266 4% 0% 77
4 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 3611 4% 0% 74
5 CANCER CELL 2796 1% 1% 16
6 CANCER DISCOVERY 2708 0% 2% 9
7 BREAST CANCER RESEARCH 2500 1% 1% 18
8 ACS MEDICINAL CHEMISTRY LETTERS 2294 1% 1% 14
9 CANCER RESEARCH 1840 4% 0% 66
10 ONCOGENE 1238 2% 0% 37

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 PIK3CA 1158745 10% 37% 177 Search PIK3CA Search PIK3CA
2 PI3K INHIBITOR 740966 4% 55% 77 Search PI3K+INHIBITOR Search PI3K+INHIBITOR
3 PI3K 497947 15% 11% 266 Search PI3K Search PI3K
4 P110 ALPHA 487142 2% 80% 35 Search P110+ALPHA Search P110+ALPHA
5 PI3K ALPHA 241338 1% 69% 20 Search PI3K+ALPHA Search PI3K+ALPHA
6 PIK3CA MUTATION 224170 2% 41% 31 Search PIK3CA+MUTATION Search PIK3CA+MUTATION
7 P110 BETA 203603 1% 73% 16 Search P110+BETA Search P110+BETA
8 BEZ235 183707 1% 50% 21 Search BEZ235 Search BEZ235
9 ZSTK474 163304 1% 67% 14 Search ZSTK474 Search ZSTK474
10 NVP BEZ235 160738 1% 44% 21 Search NVP+BEZ235 Search NVP+BEZ235

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1


rank cluster_id2 link
1 7306 PI3K GAMMA//LYMPHOCYTE SIGNALLING DEV//PI3K DELTA
2 6660 PDK1//AKT//AKT2
3 38283 OXIDATIVE BALANCE SCORE//AFFLIATED NANJING CHILDRENS HOSP//AKT1 SNP RS2498804
4 1321 MTOR//RAPAMYCIN//MTORC2
5 2970 PTEN//COWDEN SYNDROME//LHERMITTE DUCLOS DISEASE
6 7207 FULVESTRANT//ENDOCRINE RESISTANCE//ENDOCRINE THERAPY
7 21842 RESEARCH BIOPSY//PRECISION ONCOLOGY//PERSONALIZED CANC THER Y
8 3197 TRASTUZUMAB//LAPATINIB//PERTUZUMAB
9 31892 HALENAQUINONE//FURANOSTEROIDS//PERHYDROPHENANTHRENES
10 36609 PHLPP//PHLPP1//PHLPP2

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