Class information for:
Level 1: PDK1//AKT//AKT2

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
183 3       NOONAN SYNDROME//PTEN//CELL BIOLOGY 56293
1016 2             PTEN//MTOR//PI3K 10616
6660 1                   PDK1//AKT//AKT2 1487

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 PDK1 authKW 573030 5% 40% 67
2 AKT authKW 274341 21% 4% 314
3 AKT2 authKW 224967 3% 28% 38
4 AKT ISOFORMS authKW 207314 1% 65% 15
5 PKB authKW 204079 3% 19% 51
6 AKT1 authKW 196387 4% 17% 53
7 PROTEIN KINASE B authKW 150374 4% 11% 65
8 AGC KINASE authKW 140232 1% 44% 15
9 AKT INHIBITOR authKW 138684 2% 27% 24
10 GRP PHOSPHOSITES address 116552 1% 50% 11

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Cell Biology 4774 30% 0% 443
2 Oncology 3898 28% 0% 412
3 Biochemistry & Molecular Biology 3398 41% 0% 607
4 Chemistry, Medicinal 1073 9% 0% 128
5 Biophysics 149 5% 0% 70
6 Genetics & Heredity 86 5% 0% 69
7 Pathology 71 3% 0% 39
8 Medicine, Research & Experimental 57 4% 0% 53
9 Chemistry, Organic 54 4% 0% 66
10 Developmental Biology 30 1% 0% 19

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 GRP PHOSPHOSITES 116552 1% 50% 11
2 ONCOL DRUG METAB PHARMACOKINET 63580 0% 100% 3
3 PROT PHOSPHORYLAT UNIT 60172 2% 8% 35
4 STRUCT BIOCHEM UNIT 58866 0% 56% 5
5 MOL CELLULAR BIOL NUTR SCI 42386 0% 100% 2
6 SELECTSCREEN SERV 42386 0% 100% 2
7 ONCOL BIOL 32375 1% 17% 9
8 PHARMACOLMETAB DIS CELL SIGNALING 31787 0% 50% 3
9 CELL BIOL INTEGRAT REGENERAT MED IGEN 28256 0% 67% 2
10 PATHOL INTERDISCIPLINARY ONCOL 28256 0% 67% 2

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 CELLULAR SIGNALLING 4193 2% 1% 30
2 ONCOGENE 2059 3% 0% 43
3 CURRENT CANCER DRUG TARGETS 1694 1% 1% 9
4 JOURNAL OF BIOLOGICAL CHEMISTRY 1625 8% 0% 113
5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 1594 3% 0% 45
6 SCIENCE SIGNALING 1304 1% 1% 10
7 MOLECULAR CANCER THERAPEUTICS 1264 1% 0% 16
8 MOLECULAR AND CELLULAR BIOLOGY 978 2% 0% 33
9 CANCER RESEARCH 798 3% 0% 40
10 CANCER DISCOVERY 644 0% 1% 4

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 PDK1 573030 5% 40% 67 Search PDK1 Search PDK1
2 AKT 274341 21% 4% 314 Search AKT Search AKT
3 AKT2 224967 3% 28% 38 Search AKT2 Search AKT2
4 AKT ISOFORMS 207314 1% 65% 15 Search AKT+ISOFORMS Search AKT+ISOFORMS
5 PKB 204079 3% 19% 51 Search PKB Search PKB
6 AKT1 196387 4% 17% 53 Search AKT1 Search AKT1
7 PROTEIN KINASE B 150374 4% 11% 65 Search PROTEIN+KINASE+B Search PROTEIN+KINASE+B
8 AGC KINASE 140232 1% 44% 15 Search AGC+KINASE Search AGC+KINASE
9 AKT INHIBITOR 138684 2% 27% 24 Search AKT+INHIBITOR Search AKT+INHIBITOR
10 AKT KINASE INHIBITORS 105966 0% 100% 5 Search AKT+KINASE+INHIBITORS Search AKT+KINASE+INHIBITORS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1


rank cluster_id2 link
1 36609 PHLPP//PHLPP1//PHLPP2
2 4527 PIK3CA//PI3K INHIBITOR//PI3K
3 38706 UBAP2L//AMMONIA INDUCED APOPTOSIS//BAD APOPTOSIS PATHWAY
4 35515 PKN//PRK1//PROTEIN KINASE C RELATED KINASE
5 38283 OXIDATIVE BALANCE SCORE//AFFLIATED NANJING CHILDRENS HOSP//AKT1 SNP RS2498804
6 35536 GIRDIN//GIV//GROWTH FACTOR RECEPTOR TYROSINE KINASE
7 7306 PI3K GAMMA//LYMPHOCYTE SIGNALLING DEV//PI3K DELTA
8 1321 MTOR//RAPAMYCIN//MTORC2
9 2970 PTEN//COWDEN SYNDROME//LHERMITTE DUCLOS DISEASE
10 9362 FOXO1//FOXO//FOXO3A

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