Class information for:
Level 1: FARNESOID X RECEPTOR//FXR//TGR5

Basic class information

Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes

The table includes all classes above and classes immediately below the current class.



Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
221 3       GASTROENTEROLOGY & HEPATOLOGY//LAPAROSCOPIC CHOLECYSTECTOMY//PRIMARY BILIARY CIRRHOSIS 49830
417 2             BILE ACIDS//GALLSTONES//FARNESOID X RECEPTOR 16878
5707 1                   FARNESOID X RECEPTOR//FXR//TGR5 1616

Terms with highest relevance score



rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 FARNESOID X RECEPTOR authKW 2773378 13% 67% 213
2 FXR authKW 1582348 9% 58% 141
3 TGR5 authKW 1347923 5% 80% 86
4 BILE ACIDS authKW 554344 18% 10% 298
5 SMALL HETERODIMER PARTNER authKW 477760 2% 70% 35
6 FARNESOID X RECEPTOR FXR authKW 372720 2% 66% 29
7 GW4064 authKW 270757 1% 73% 19
8 BILE ACID RECEPTOR authKW 219711 1% 87% 13
9 GENE REGULAT DRUG DISCOVERY address 190251 1% 51% 19
10 GPBAR1 authKW 187207 1% 80% 12

Web of Science journal categories



chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Gastroenterology & Hepatology 7232 20% 0% 327
2 Biochemistry & Molecular Biology 1917 31% 0% 500
3 Endocrinology & Metabolism 1804 14% 0% 223
4 Chemistry, Medicinal 1397 9% 0% 151
5 Cell Biology 684 12% 0% 199
6 Pharmacology & Pharmacy 604 14% 0% 219
7 Physiology 300 6% 0% 91
8 Biophysics 192 5% 0% 81
9 Medicine, Research & Experimental 135 5% 0% 75
10 Toxicology 66 3% 0% 44

Address terms



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 GENE REGULAT DRUG DISCOVERY 190251 1% 51% 19
2 EXPT MOL HEPATOL 122548 1% 29% 22
3 PHARMACEUT DEV PHYS PROPERTIES DEVELOPABIL 81254 0% 83% 5
4 MOL DISCOVERY BIOL REAGENTS ASSAY DEV 58504 0% 100% 3
5 MOL DISCOVERY COMPUTAT STRUCT CHEM 58504 0% 100% 3
6 INTEGRAT MED SCI 55893 2% 7% 39
7 UNITE RECH 545 54166 0% 56% 5
8 LIVER DIGEST METAB DIS 51409 2% 8% 32
9 GI 15A 48748 0% 50% 5
10 DIPARTIMENTO SCI CHIRURG BIOMED 44316 0% 45% 5

Journals



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 7668 3% 1% 50
2 DIGESTIVE DISEASES 7326 2% 1% 26
3 HEPATOLOGY 6955 4% 1% 66
4 JOURNAL OF LIPID RESEARCH 5787 3% 1% 51
5 MOLECULAR ENDOCRINOLOGY 4442 2% 1% 36
6 CELL METABOLISM 2401 1% 1% 14
7 JOURNAL OF HEPATOLOGY 2082 2% 0% 29
8 MOLECULAR ASPECTS OF MEDICINE 1875 0% 1% 8
9 GASTROENTEROLOGY 1096 2% 0% 28
10 JOURNAL OF BIOLOGICAL CHEMISTRY 1088 6% 0% 98

Author Key Words



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 FARNESOID X RECEPTOR 2773378 13% 67% 213 Search FARNESOID+X+RECEPTOR Search FARNESOID+X+RECEPTOR
2 FXR 1582348 9% 58% 141 Search FXR Search FXR
3 TGR5 1347923 5% 80% 86 Search TGR5 Search TGR5
4 BILE ACIDS 554344 18% 10% 298 Search BILE+ACIDS Search BILE+ACIDS
5 SMALL HETERODIMER PARTNER 477760 2% 70% 35 Search SMALL+HETERODIMER+PARTNER Search SMALL+HETERODIMER+PARTNER
6 FARNESOID X RECEPTOR FXR 372720 2% 66% 29 Search FARNESOID+X+RECEPTOR+FXR Search FARNESOID+X+RECEPTOR+FXR
7 GW4064 270757 1% 73% 19 Search GW4064 Search GW4064
8 BILE ACID RECEPTOR 219711 1% 87% 13 Search BILE+ACID+RECEPTOR Search BILE+ACID+RECEPTOR
9 GPBAR1 187207 1% 80% 12 Search GPBAR1 Search GPBAR1
10 NUCLEAR RECEPTOR 177554 10% 6% 159 Search NUCLEAR+RECEPTOR Search NUCLEAR+RECEPTOR

Core articles

The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1



rank cluster_id2 link
1 17508 BILE ACID MALABSORPTION//SEHCAT//75SEHCAT
2 13663 CHOLESTEROL 7 ALPHA HYDROXYLASE//BILE ACID SYNTHESIS//7 ALPHA HYDROXYCHOLESTEROL
3 26957 BILE ACID SEQUESTRANT//COLESEVELAM//COLESEVELAM HYDROCHLORIDE
4 9025 INTRAHEPATIC CHOLESTASIS OF PREGNANCY//PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS//OBSTETRIC CHOLESTASIS
5 13273 FGF21//FIBROBLAST GROWTH FACTOR 21//FGF19
6 12117 URSODEOXYCHOLIC ACID//TAUROURSODEOXYCHOLIC ACID//CHOLESTASIS
7 3983 PREGNANE X RECEPTOR//PXR//CONSTITUTIVE ANDROSTANE RECEPTOR
8 7401 BILE ACIDS//SULFATED BILE ACID//FETAL BILE ACID
9 9872 LIVER X RECEPTOR//LXR//T0901317
10 24611 7 ALPHA DEHYDROXYLATION//7 ALPHA HYDROXYSTEROID DEHYDROGENASE//CLOSTRIDIUM SCINDENS

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