Class information for:
Level 1: PREGNANE X RECEPTOR//PXR//CONSTITUTIVE ANDROSTANE RECEPTOR

Basic class information

Last years might be incomplete

Hierarchy of classes

The table includes all classes above and classes immediately below the current class.

Cluster id	Level	Cluster label	#P
0	4	ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY	2934640
273	3	P GLYCOPROTEIN//MULTIDRUG RESISTANCE//DRUG METABOLISM AND DISPOSITION	43782
444	2	CYTOCHROME P450//EPOXYEICOSATRIENOIC ACIDS//CYP2D6	16462
3983	1	PREGNANE X RECEPTOR//PXR//CONSTITUTIVE ANDROSTANE RECEPTOR	1903

Terms with highest relevance score

rank	Category	termType	chi_square	shrOfCwithTerm	shrOfTermInClass	termInClass
1	PREGNANE X RECEPTOR	authKW	2482489	11%	69%	218
2	PXR	authKW	1954939	10%	62%	191
3	CONSTITUTIVE ANDROSTANE RECEPTOR	authKW	1706422	7%	79%	130
4	PHARMACOGENET SECT	address	542404	5%	35%	93
5	CAR	authKW	363765	6%	19%	113
6	PREGNANE X RECEPTOR PXR	authKW	294575	1%	68%	26
7	NUCLEAR RECEPTOR	authKW	288736	12%	8%	220
8	CONSTITUTIVE ANDROSTANE RECEPTOR CAR	authKW	273743	1%	72%	23
9	REPROD DEV TOXICOL	address	253581	5%	16%	95
10	CYP3A4	authKW	164191	6%	9%	108

Web of Science journal categories

chi_square_rank	Category	chi_square	shrOfCwithTerm	shrOfTermInClass	termInClass
1	Pharmacology & Pharmacy	14608	51%	0%	968
2	Toxicology	6503	18%	0%	341
3	Biochemistry & Molecular Biology	1394	25%	0%	485
4	Biophysics	230	5%	0%	96
5	Chemistry, Medicinal	177	4%	0%	69
6	Endocrinology & Metabolism	131	4%	0%	85
7	Cell Biology	74	5%	0%	102
8	Integrative & Complementary Medicine	70	1%	0%	17
9	Gastroenterology & Hepatology	68	3%	0%	49
10	Medicine, Research & Experimental	38	3%	0%	56

Address terms

chi_square_rank	term	chi_square	shrOfCwithTerm	shrOfTermInClass	termInClass
1	PHARMACOGENET SECT	542404	5%	35%	93
2	REPROD DEV TOXICOL	253581	5%	16%	95
3	NUCL RECEPTOR DISCOVERY	83938	1%	30%	17
4	PL PHARMACEUT EDUC	75695	0%	57%	8
5	U632	67267	1%	25%	16
6	DRUG METAB MOL TOXICOL	67165	1%	16%	25
7	PHARMACOGENET	54710	3%	6%	54
8	CHEM BIOL THER EUT	42268	2%	8%	31
9	PHARMACOL NEUROBIOL	40535	1%	12%	21
10	HLTH SCI MED TOXICOL	33120	0%	100%	2

Journals

chi_square_rank	term	chi_square	shrOfCwithTerm	shrOfTermInClass	termInClass
1	DRUG METABOLISM AND DISPOSITION	93469	11%	3%	207
2	DRUG METABOLISM AND PHARMACOKINETICS	25392	2%	5%	34
3	CURRENT DRUG METABOLISM	23206	2%	4%	40
4	MOLECULAR PHARMACOLOGY	17095	5%	1%	101
5	TOXICOLOGICAL SCIENCES	10175	3%	1%	56
6	DRUG METABOLISM REVIEWS	7932	1%	2%	22
7	EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY	6127	1%	2%	22
8	XENOBIOTICA	5679	2%	1%	37
9	BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS	3342	1%	1%	15
10	BIOCHEMICAL PHARMACOLOGY	3218	3%	0%	61

Author Key Words

chi_square_rank	term	chi_square	shrOfCwithTerm	shrOfTermInClass	termInClass	LCSH search	Wikipedia search
1	PREGNANE X RECEPTOR	2482489	11%	69%	218	Search PREGNANE+X+RECEPTOR	Search PREGNANE+X+RECEPTOR
2	PXR	1954939	10%	62%	191	Search PXR	Search PXR
3	CONSTITUTIVE ANDROSTANE RECEPTOR	1706422	7%	79%	130	Search CONSTITUTIVE+ANDROSTANE+RECEPTOR	Search CONSTITUTIVE+ANDROSTANE+RECEPTOR
4	CAR	363765	6%	19%	113	Search CAR	Search CAR
5	PREGNANE X RECEPTOR PXR	294575	1%	68%	26	Search PREGNANE+X+RECEPTOR+PXR	Search PREGNANE+X+RECEPTOR+PXR
6	NUCLEAR RECEPTOR	288736	12%	8%	220	Search NUCLEAR+RECEPTOR	Search NUCLEAR+RECEPTOR
7	CONSTITUTIVE ANDROSTANE RECEPTOR CAR	273743	1%	72%	23	Search CONSTITUTIVE+ANDROSTANE+RECEPTOR+CAR	Search CONSTITUTIVE+ANDROSTANE+RECEPTOR+CAR
8	CYP3A4	164191	6%	9%	108	Search CYP3A4	Search CYP3A4
9	XENOBIOTIC RECEPTOR	133577	1%	73%	11	Search XENOBIOTIC+RECEPTOR	Search XENOBIOTIC+RECEPTOR
10	HPXR	105980	0%	80%	8	Search HPXR	Search HPXR

Core articles

The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1

rank	cluster_id2	link
1	30972	PHARMACOL TOXICOL HUMAN ENVIRONM TOXICOL//PHARMACOEPIGENETICS//HSA MIR 29A 3P
2	5707	FARNESOID X RECEPTOR//FXR//TGR5
3	2923	S BIOCHEM//CYP2C12//ONE DAY TREATMENT
4	9019	CYP2C8//COCKTAIL//MECHANISM BASED INHIBITION
5	38739	26S PROTEASOME NON ATPASE REGULATORY SUBUNIT 13//BIOMED SEVILLE IBISSERV INFECT DIS//DRAKSARISTA
6	19382	PHARMACOKINET BIOANAL//MICROMINIPIG//MINIPIG
7	3381	CYP3A5//TACROLIMUS//6 BETA HYDROXYCORTISOL
8	12327	THERAPEUTIC PROTEIN DRUG INTERACTION//ROLLINS 5119//9000 X G SUPERNATANT
9	30492	CONAZOLES//TRIADIMEFON//MYCLOBUTANIL
10	11078	HERB DRUG INTERACTION//ST JOHNS WORT//DRUG HERB INTERACTION

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Class information for: Level 1: PREGNANE X RECEPTOR//PXR//CONSTITUTIVE ANDROSTANE RECEPTOR