Class information for:
Level 2: CYTOCHROME P450//EPOXYEICOSATRIENOIC ACIDS//CYP2D6

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
273 3       P GLYCOPROTEIN//MULTIDRUG RESISTANCE//DRUG METABOLISM AND DISPOSITION 43782
444 2             CYTOCHROME P450//EPOXYEICOSATRIENOIC ACIDS//CYP2D6 16462
1473 1                   CYP2D6//DEBRISOQUINE//CYP2C19 2652
2390 1                   EPOXYEICOSATRIENOIC ACIDS//SOLUBLE EPOXIDE HYDROLASE//20 HYDROXYEICOSATETRAENOIC ACID 2296
2923 1                   S BIOCHEM//CYP2C12//ONE DAY TREATMENT 2142
3983 1                   PREGNANE X RECEPTOR//PXR//CONSTITUTIVE ANDROSTANE RECEPTOR 1903
9019 1                   CYP2C8//COCKTAIL//MECHANISM BASED INHIBITION 1225
10263 1                   CYP2E1//CHLORZOXAZONE//CYTOCHROME P450 2E1 1108
12327 1                   THERAPEUTIC PROTEIN DRUG INTERACTION//ROLLINS 5119//9000 X G SUPERNATANT 944
13746 1                   4 IPOMEANOL//CYP4B1//CLARA CELL 846
14927 1                   CYP1B1//CYTOCHROME P4501B1//CYP2S1 768
16270 1                   CYP2A6//CYP2A5//CYP2A13 691
18214 1                   NASAL TOXICITY//BOWMANS GLANDS//OLFACTORY MUCOSA 587
19382 1                   PHARMACOKINET BIOANAL//MICROMINIPIG//MINIPIG 532
22934 1                   5 METHOXYTRYPTAMINE O DEMETHYLATION//BRAIN DRUG METABOLISM//CHIMERIC SIGNALS 386
23024 1                   OMEGA HYDROXYLATION//CYP4F12//MED TONEYAMA TB 382

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 CYTOCHROME P450 authKW 631419 10% 20% 1683
2 EPOXYEICOSATRIENOIC ACIDS authKW 485202 2% 80% 317
3 CYP2D6 authKW 434378 3% 45% 504
4 SOLUBLE EPOXIDE HYDROLASE authKW 368663 1% 84% 229
5 PREGNANE X RECEPTOR authKW 302594 1% 71% 224
6 DRUG METABOLISM AND DISPOSITION journal 265611 6% 14% 1028
7 PXR authKW 230407 1% 62% 193
8 CONSTITUTIVE ANDROSTANE RECEPTOR authKW 206237 1% 81% 133
9 DEBRISOQUINE authKW 170378 1% 77% 116
10 20 HYDROXYEICOSATETRAENOIC ACID authKW 167313 1% 83% 105

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Pharmacology & Pharmacy 96763 45% 1% 7389
2 Toxicology 38546 15% 1% 2466
3 Biochemistry & Molecular Biology 7171 21% 0% 3441
4 Biophysics 2507 6% 0% 908
5 Chemistry, Medicinal 739 3% 0% 457
6 Physiology 562 3% 0% 501
7 Oncology 465 5% 0% 833
8 Medical Laboratory Technology 456 1% 0% 186
9 Peripheral Vascular Diseases 454 2% 0% 382
10 Endocrinology & Metabolism 269 3% 0% 475

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 PHARMACOGENET SECT 122300 1% 49% 130
2 PHARMACOKINET BIOANAL 70210 0% 61% 60
3 DRUG METAB 32979 1% 10% 168
4 REPROD DEV TOXICOL 31022 1% 17% 98
5 DRUG METAB PHARMACOKINET 28283 1% 7% 214
6 CLIN PHARMACOL 26990 4% 2% 612
7 CICAB CLIN 22972 0% 52% 23
8 MOL TOXICOL 21650 1% 7% 160
9 UCD CANC 21054 0% 48% 23
10 PHARMACOGENET 19836 1% 11% 96

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 DRUG METABOLISM AND DISPOSITION 265611 6% 14% 1028
2 PHARMACOGENETICS 89777 1% 22% 211
3 XENOBIOTICA 65411 2% 9% 369
4 BIOCHEMICAL PHARMACOLOGY 35419 4% 3% 594
5 DRUG METABOLISM AND PHARMACOKINETICS 33440 1% 15% 115
6 CLINICAL PHARMACOLOGY & THERAPEUTICS 32409 2% 5% 319
7 CURRENT DRUG METABOLISM 30846 1% 12% 136
8 DRUG METABOLISM REVIEWS 18851 1% 10% 100
9 MOLECULAR PHARMACOLOGY 18581 2% 3% 313
10 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 15283 2% 3% 260

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 CYTOCHROME P450 631419 10% 20% 1683 Search CYTOCHROME+P450 Search CYTOCHROME+P450
2 EPOXYEICOSATRIENOIC ACIDS 485202 2% 80% 317 Search EPOXYEICOSATRIENOIC+ACIDS Search EPOXYEICOSATRIENOIC+ACIDS
3 CYP2D6 434378 3% 45% 504 Search CYP2D6 Search CYP2D6
4 SOLUBLE EPOXIDE HYDROLASE 368663 1% 84% 229 Search SOLUBLE+EPOXIDE+HYDROLASE Search SOLUBLE+EPOXIDE+HYDROLASE
5 PREGNANE X RECEPTOR 302594 1% 71% 224 Search PREGNANE+X+RECEPTOR Search PREGNANE+X+RECEPTOR
6 PXR 230407 1% 62% 193 Search PXR Search PXR
7 CONSTITUTIVE ANDROSTANE RECEPTOR 206237 1% 81% 133 Search CONSTITUTIVE+ANDROSTANE+RECEPTOR Search CONSTITUTIVE+ANDROSTANE+RECEPTOR
8 DEBRISOQUINE 170378 1% 77% 116 Search DEBRISOQUINE Search DEBRISOQUINE
9 20 HYDROXYEICOSATETRAENOIC ACID 167313 1% 83% 105 Search 20+HYDROXYEICOSATETRAENOIC+ACID Search 20+HYDROXYEICOSATETRAENOIC+ACID
10 CYP2A6 145485 1% 61% 124 Search CYP2A6 Search CYP2A6

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 2


rank cluster_id2 link
1 1816 CYTOCHROME P450//CYTOCHROME P450CAM//CYTOCHROME P450 BM3
2 3278 MONOETHYLGLYCINEXYLIDIDE//MEGX//METHACETIN
3 3461 EPOXIDE HYDROLASE//MICROSOMAL EPOXIDE HYDROLASE//CIS EPOXYSUCCINATE HYDROLASE
4 1763 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//CACO 2//BIOPHARMACEUTICS & DRUG DISPOSITION
5 2024 GSTM1//GSTT1//GLUTATHIONE S TRANSFERASE
6 3634 FLAVIN CONTAINING MONOOXYGENASE//TRIMETHYLAMINURIA//FMO3
7 1730 BIOARTIFICIAL LIVER//HEPATOCYTES//HEPATOCYTE TRANSPLANTATION
8 2392 N NITROSAMINES//NITROSAMINES//NDMA
9 2960 PROTON PUMP INHIBITORS//OMEPRAZOLE//PANTOPRAZOLE
10 714 HETEROCYCLIC AMINES//DNA ADDUCTS//HETEROCYCLIC AROMATIC AMINES

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