Class information for:
Level 1: CYP2D6//DEBRISOQUINE//CYP2C19

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
273 3       P GLYCOPROTEIN//MULTIDRUG RESISTANCE//DRUG METABOLISM AND DISPOSITION 43782
444 2             CYTOCHROME P450//EPOXYEICOSATRIENOIC ACIDS//CYP2D6 16462
1473 1                   CYP2D6//DEBRISOQUINE//CYP2C19 2652

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 CYP2D6 authKW 2409708 18% 43% 476
2 DEBRISOQUINE authKW 987042 4% 74% 112
3 CYP2C19 authKW 612774 7% 26% 195
4 POOR METABOLIZER authKW 347881 2% 60% 49
5 CYP2D6 POLYMORPHISM authKW 307970 1% 72% 36
6 PHARMACOGENETICS journal 301829 6% 16% 155
7 MEPHENYTOIN authKW 301216 1% 69% 37
8 ULTRARAPID METABOLIZER authKW 183322 1% 86% 18
9 CYTOCHROME P450 2D6 authKW 175707 2% 34% 43
10 CICAB CLIN address 142836 1% 52% 23

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Pharmacology & Pharmacy 35287 66% 0% 1751
2 Medical Laboratory Technology 2520 5% 0% 141
3 Toxicology 1637 8% 0% 215
4 Psychiatry 643 7% 0% 177
5 Genetics & Heredity 350 6% 0% 164
6 Medicine, Legal 161 1% 0% 25
7 Clinical Neurology 90 4% 0% 111
8 Medicine, Research & Experimental 45 3% 0% 75
9 Chemistry, Analytical 39 3% 0% 87
10 Biochemical Research Methods 37 2% 0% 60

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 CICAB CLIN 142836 1% 52% 23
2 SECT DEV PHARMACOL EXPT THER EUT 72764 1% 44% 14
3 CLIN PHARMACOL TOXICOL THER EUT INNOVAT 44606 0% 29% 13
4 CICAB 27716 0% 33% 7
5 CLIN PHARMACOL 27566 9% 1% 245
6 DEV PHARMACOL EXPT THER EUT 26734 0% 75% 3
7 PHARMACOGENET CORE 26734 0% 75% 3
8 CLIN PHARMACOL TOXICOL INNOVAT THER EUT 23765 0% 100% 2
9 S HLTH CHEM 23765 0% 100% 2
10 NUCLEOTIDE POLYMORPHISM 21386 0% 60% 3

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 PHARMACOGENETICS 301829 6% 16% 155
2 CLINICAL PHARMACOLOGY & THERAPEUTICS 77832 7% 3% 197
3 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 49023 6% 2% 172
4 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 42575 6% 2% 172
5 PHARMACOGENOMICS 26458 2% 3% 64
6 DRUG METABOLISM AND DISPOSITION 14000 4% 1% 95
7 THERAPEUTIC DRUG MONITORING 13157 2% 2% 65
8 PHARMACOGENOMICS JOURNAL 11010 1% 3% 28
9 XENOBIOTICA 6289 2% 1% 46
10 PHARMACOGENETICS AND GENOMICS 5355 1% 2% 23

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 CYP2D6 2409708 18% 43% 476 Search CYP2D6 Search CYP2D6
2 DEBRISOQUINE 987042 4% 74% 112 Search DEBRISOQUINE Search DEBRISOQUINE
3 CYP2C19 612774 7% 26% 195 Search CYP2C19 Search CYP2C19
4 POOR METABOLIZER 347881 2% 60% 49 Search POOR+METABOLIZER Search POOR+METABOLIZER
5 CYP2D6 POLYMORPHISM 307970 1% 72% 36 Search CYP2D6+POLYMORPHISM Search CYP2D6+POLYMORPHISM
6 MEPHENYTOIN 301216 1% 69% 37 Search MEPHENYTOIN Search MEPHENYTOIN
7 PHARMACOGENETICS 191803 10% 6% 266 Search PHARMACOGENETICS Search PHARMACOGENETICS
8 ULTRARAPID METABOLIZER 183322 1% 86% 18 Search ULTRARAPID+METABOLIZER Search ULTRARAPID+METABOLIZER
9 CYTOCHROME P450 2D6 175707 2% 34% 43 Search CYTOCHROME+P450+2D6 Search CYTOCHROME+P450+2D6
10 CYP2D610 124175 1% 58% 18 Search CYP2D610 Search CYP2D610

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1


rank cluster_id2 link
1 22765 ENDOXIFEN//TAMOXIFEN//CYP2D6
2 22934 5 METHOXYTRYPTAMINE O DEMETHYLATION//BRAIN DRUG METABOLISM//CHIMERIC SIGNALS
3 30969 PERHEXILINE//HYDROXYPERHEXILINE//CARDIOL CLIN PHARMACOL
4 21242 DEXTROMETHORPHAN//DEXTRORPHAN//DIMEMORFAN
5 26393 MED HOSP PHARM YAHATANISHI KU//PROPRANOLOL METABOLITE//4 HYDROXYPROPRANOLOL
6 9019 CYP2C8//COCKTAIL//MECHANISM BASED INHIBITION
7 8566 ESCITALOPRAM//CITALOPRAM//NORFLUOXETINE
8 18196 ANTIDEPRESSANT RESPONSE//NOREPINEPHRINE TRANSPORTER GENE//GENDEP
9 9715 PHARMACOGENOMICS//PERSONALIZED MEDICINE//PHARMACOGENETICS
10 2249 CYP2C9//VKORC1//WARFARIN

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