Class information for:
Level 1: DIHYDROFOLATE REDUCTASE//PROMOTING VIBRATION//HYDROGEN TUNNELING

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
200 3       ONCOLOGY//PACLITAXEL//THYMIDYLATE SYNTHASE 52806
1389 2             PEMETREXED//NON SMALL CELL LUNG CANCER//ANTIFOLATE 8368
7441 1                   DIHYDROFOLATE REDUCTASE//PROMOTING VIBRATION//HYDROGEN TUNNELING 1392

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 DIHYDROFOLATE REDUCTASE authKW 535036 9% 20% 119
2 PROMOTING VIBRATION authKW 183380 1% 90% 9
3 HYDROGEN TUNNELING authKW 181912 1% 54% 15
4 KINETIC ISOTOPE EFFECT authKW 119067 4% 11% 50
5 ENZYME DYNAMICS authKW 101858 1% 30% 15
6 HYDROGEN TUNNELLING authKW 96589 1% 53% 8
7 LABELED NICOTINAMIDE authKW 90559 0% 100% 4
8 10065 BARNES CANYON RD address 67919 0% 100% 3
9 ROLE OF FLEXIBLE LOOP authKW 67919 0% 100% 3
10 DHFR authKW 52487 2% 10% 23

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Biochemistry & Molecular Biology 5362 51% 0% 715
2 Chemistry, Multidisciplinary 874 19% 0% 258
3 Biophysics 867 10% 0% 138
4 Chemistry, Medicinal 748 8% 0% 105
5 Chemistry, Physical 437 15% 0% 204
6 Physics, Atomic, Molecular & Chemical 217 6% 0% 86
7 Biochemical Research Methods 129 4% 0% 58
8 Chemistry, Organic 21 4% 0% 49
9 Mathematical & Computational Biology 19 1% 0% 14
10 Crystallography 19 2% 0% 23

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 10065 BARNES CANYON RD 67919 0% 100% 3
2 COMPUTAT MOL BIOL DRUG DESIGN GRP 51448 0% 45% 5
3 SCI TECHNOL BIOCHEM 29105 0% 43% 3
4 BIOCHEM MOLEC BIOL POB 10008 22640 0% 100% 1
5 BIOTECNOL PLANEJAMENTO DESENVOLVIMENT 22640 0% 100% 1
6 CALIF QUANTITAT BIOSCI B3 22640 0% 100% 1
7 CHEM SEELEY G MUDD 418 22640 0% 100% 1
8 CIENCIASREQUIMTE 22640 0% 100% 1
9 CMBDDG 22640 0% 100% 1
10 CNRS URA 464 22640 0% 100% 1

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 BIOCHEMISTRY 20395 16% 0% 220
2 JOURNAL OF MEDICINAL CHEMISTRY 3412 4% 0% 58
3 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2538 8% 0% 105
4 JOURNAL OF BIOCHEMISTRY 1967 2% 0% 31
5 PROTEIN ENGINEERING 1669 1% 1% 13
6 ADVANCES IN PHYSICAL ORGANIC CHEMISTRY 1664 0% 2% 3
7 JOURNAL OF PHYSICAL CHEMISTRY B 1431 4% 0% 51
8 JOURNAL OF PHYSICAL ORGANIC CHEMISTRY 1261 1% 0% 14
9 PROGRESS IN MEDICINAL CHEMISTRY 1256 0% 6% 1
10 JOURNAL OF COMPUTATIONAL CHEMISTRY 1011 1% 0% 17

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 DIHYDROFOLATE REDUCTASE 535036 9% 20% 119 Search DIHYDROFOLATE+REDUCTASE Search DIHYDROFOLATE+REDUCTASE
2 PROMOTING VIBRATION 183380 1% 90% 9 Search PROMOTING+VIBRATION Search PROMOTING+VIBRATION
3 HYDROGEN TUNNELING 181912 1% 54% 15 Search HYDROGEN+TUNNELING Search HYDROGEN+TUNNELING
4 KINETIC ISOTOPE EFFECT 119067 4% 11% 50 Search KINETIC+ISOTOPE+EFFECT Search KINETIC+ISOTOPE+EFFECT
5 ENZYME DYNAMICS 101858 1% 30% 15 Search ENZYME+DYNAMICS Search ENZYME+DYNAMICS
6 HYDROGEN TUNNELLING 96589 1% 53% 8 Search HYDROGEN+TUNNELLING Search HYDROGEN+TUNNELLING
7 LABELED NICOTINAMIDE 90559 0% 100% 4 Search LABELED+NICOTINAMIDE Search LABELED+NICOTINAMIDE
8 ROLE OF FLEXIBLE LOOP 67919 0% 100% 3 Search ROLE+OF+FLEXIBLE+LOOP Search ROLE+OF+FLEXIBLE+LOOP
9 DHFR 52487 2% 10% 23 Search DHFR Search DHFR
10 8 ALKYLPTERINS 45279 0% 100% 2 Search 8+ALKYLPTERINS Search 8+ALKYLPTERINS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1


rank cluster_id2 link
1 18645 HPPK//DIHYDROFOLATE REDUCTASE//DIHYDROPTEROATE SYNTHASE
2 15031 LINK ATOM//EXTREMELY LOCALIZED MOLECULAR ORBITALS//QM MM
3 17615 THYMIDYLATE SYNTHASE//THYX//DEOXYTUBULOSINE
4 25990 JOURNAL OF MOLECULAR GRAPHICS//SPACE FILLING MOLECULAR MODELS//DESK TOP MOLECULAR MODELING
5 15897 PROTON COUPLED ELECTRON TRANSFER//CYCLIC VOLTABSORPTOMETRY CVA//9 OCTYLADENINE
6 26462 PROTEIN SWITCH//CIRCULAR PERMUTATION//BIOMED ST PAU IIB SANTPAU
7 2087 REDUCED FOLATE CARRIER//FOLYLPOLYGLUTAMATE SYNTHETASE//ANTIFOLATE
8 13458 KETOSTEROID ISOMERASE//LOW BARRIER HYDROGEN BOND//JULIUS SPOKOJNY BIOORGAN CHEM
9 30105 HALOPHILIC//HALOPHILIC ADAPTATION//PL MOL MICROBIOL
10 10073 NADH MODEL//NADPH MODEL//1 BENZYL 1 4 DIHYDRONICOTINAMIDE

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