Class information for:
Level 2: JNK//ERK5//COFFIN LOWRY SYNDROME

Basic class information

Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes

The table includes all classes above and classes immediately below the current class.



Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
183 3       NOONAN SYNDROME//PTEN//CELL BIOLOGY 56293
1406 2             JNK//ERK5//COFFIN LOWRY SYNDROME 8266
4735 1                   JNK//MKK4//JNK3 1761
6295 1                   MK2//P38 INHIBITORS//P38 ALPHA 1530
10959 1                   MAP KINASE KINASE//MAP KINASE ACTIVATOR//MICROTUBULE ASSOCIATED PROTEIN 2 KINASE 1048
13383 1                   DUAL SPECIFICITY PHOSPHATASE//MKP 1//MAP KINASE PHOSPHATASE 872
16905 1                   COFFIN LOWRY SYNDROME//RSK2//SL0101 655
17340 1                   PEA 15//ERK2//PROGRAM PHARM 633
22156 1                   ERK5//MEK5//EXTRACELLULAR SIGNAL REGULATED KINASE 5 415
23101 1                   TAK1//5Z 7 OXOZEAENOL//TAB1 380
23414 1                   ASK1//PP5//PROTEIN PHOSPHATASE 5 370
25079 1                   MAP4K4//HPK1//TNIK 315
29481 1                   TPL2//TPL 2//MAP3K8 203
37374 1                   VRK1//VRK2//EXPT THER EUT TRANSLAT ONCOL PROGRAM 84

Terms with highest relevance score



rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 JNK authKW 219979 5% 15% 392
2 ERK5 authKW 203890 1% 63% 85
3 COFFIN LOWRY SYNDROME authKW 158824 1% 89% 47
4 MAP KINASE authKW 151941 4% 12% 332
5 TAK1 authKW 140429 1% 42% 88
6 P38 authKW 138471 3% 14% 254
7 ASK1 authKW 113699 1% 38% 79
8 MK2 authKW 97040 1% 58% 44
9 DUAL SPECIFICITY PHOSPHATASE authKW 93845 1% 46% 53
10 MKP 1 authKW 90372 1% 37% 65

Web of Science journal categories



chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Biochemistry & Molecular Biology 24664 46% 0% 3791
2 Cell Biology 24104 29% 0% 2356
3 Oncology 3484 13% 0% 1039
4 Chemistry, Medicinal 3043 6% 0% 528
5 Biophysics 1813 6% 0% 527
6 Genetics & Heredity 908 6% 0% 478
7 Neurosciences 643 8% 0% 643
8 Immunology 519 6% 0% 469
9 Developmental Biology 221 1% 0% 117
10 Pharmacology & Pharmacy 211 6% 0% 475

Address terms



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 CANC UK ST S PONSE 49794 0% 93% 14
2 PROT PHOSPHORYLAT UNIT 27631 1% 13% 56
3 PROGRAM PHARM 24260 0% 58% 11
4 CR UK ST S PONSE 19054 0% 100% 5
5 INVITROGEN DISCOVERY SERV 19054 0% 100% 5
6 PROGRAM MOL SIGNAL TRANSDUCT 18385 0% 37% 13
7 CELL SIGNALING 16871 1% 5% 82
8 GODDARD S 601 15244 0% 100% 4
9 PROGRAM MOL MED 15179 1% 4% 107
10 HORMEL 14509 1% 7% 55

Journals



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 JOURNAL OF BIOLOGICAL CHEMISTRY 19780 11% 1% 911
2 CELLULAR SIGNALLING 10441 1% 2% 112
3 MOLECULAR AND CELLULAR BIOLOGY 8355 3% 1% 226
4 ONCOGENE 7625 2% 1% 196
5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 5530 2% 1% 199
6 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2214 3% 0% 215
7 EMBO JOURNAL 2122 1% 1% 102
8 BIOCHEMICAL JOURNAL 1726 1% 0% 122
9 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1521 1% 1% 44
10 JOURNAL OF MEDICINAL CHEMISTRY 1286 1% 0% 91

Author Key Words



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 JNK 219979 5% 15% 392 Search JNK Search JNK
2 ERK5 203890 1% 63% 85 Search ERK5 Search ERK5
3 COFFIN LOWRY SYNDROME 158824 1% 89% 47 Search COFFIN+LOWRY+SYNDROME Search COFFIN+LOWRY+SYNDROME
4 MAP KINASE 151941 4% 12% 332 Search MAP+KINASE Search MAP+KINASE
5 TAK1 140429 1% 42% 88 Search TAK1 Search TAK1
6 P38 138471 3% 14% 254 Search P38 Search P38
7 ASK1 113699 1% 38% 79 Search ASK1 Search ASK1
8 MK2 97040 1% 58% 44 Search MK2 Search MK2
9 DUAL SPECIFICITY PHOSPHATASE 93845 1% 46% 53 Search DUAL+SPECIFICITY+PHOSPHATASE Search DUAL+SPECIFICITY+PHOSPHATASE
10 MKP 1 90372 1% 37% 65 Search MKP+1 Search MKP+1

Core articles

The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 2



rank cluster_id2 link
1 1898 EGR 1//C FOS//IMMEDIATE EARLY GENE
2 1549 RAS//FARNESYLTRANSFERASE//RAL
3 2278 NF KAPPA B//A20//I KAPPA B
4 2147 NOONAN SYNDROME//PROTEIN TYROSINE PHOSPHATASE//COSTELLO SYNDROME
5 1653 RHO KINASE//FASUDIL//RHO GTPASES
6 3591 14 3 3 PROTEIN//14 3 3//14 3 3 SIGMA
7 2146 PROTEIN KINASE CK2//CK2//CASEIN KINASE 2
8 3044 C EBP BETA//GADD45//CCAAT ENHANCER BINDING PROTEIN
9 1016 PTEN//MTOR//PI3K
10 4084 PAR 4//DAP KINASE//DEATH ASSOCIATED PROTEIN KINASE

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