Class information for:
Level 2: NOONAN SYNDROME//PROTEIN TYROSINE PHOSPHATASE//COSTELLO SYNDROME

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
183 3       NOONAN SYNDROME//PTEN//CELL BIOLOGY 56293
2147 2             NOONAN SYNDROME//PROTEIN TYROSINE PHOSPHATASE//COSTELLO SYNDROME 5350
1588 1                   PROTEIN TYROSINE PHOSPHATASE//PTP1B//PROTEIN TYROSINE PHOSPHATASE 1B 2600
8976 1                   SHP2//SHP 1//SHP 2 1229
9621 1                   NOONAN SYNDROME//COSTELLO SYNDROME//CARDIO FACIO CUTANEOUS SYNDROME 1168
26922 1                   PRL 3//PRL 1//PTP4A3 262
36917 1                   PTPN13//FAP 1//PTPL1 91

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 NOONAN SYNDROME authKW 1961475 8% 82% 404
2 PROTEIN TYROSINE PHOSPHATASE authKW 1105320 8% 42% 452
3 COSTELLO SYNDROME authKW 806193 3% 93% 148
4 PTPN11 authKW 593609 2% 81% 125
5 PTP1B authKW 568516 4% 51% 188
6 CARDIO FACIO CUTANEOUS SYNDROME authKW 477619 2% 97% 84
7 RASOPATHY authKW 432846 2% 76% 97
8 LEOPARD SYNDROME authKW 408356 1% 88% 79
9 SHP2 authKW 358547 2% 57% 107
10 PRL 3 authKW 353635 1% 88% 68

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Biochemistry & Molecular Biology 9209 36% 0% 1934
2 Cell Biology 6561 19% 0% 1033
3 Genetics & Heredity 5458 14% 0% 768
4 Chemistry, Medicinal 2585 7% 0% 385
5 Oncology 1938 12% 0% 633
6 Pediatrics 568 5% 0% 244
7 Biophysics 493 5% 0% 244
8 Hematology 445 4% 0% 192
9 Endocrinology & Metabolism 338 4% 0% 232
10 Medicine, Research & Experimental 204 4% 0% 191

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 EDMOND H FI ER SIGNAL TRANSDUCT 73991 1% 47% 27
2 DIPARTIMENTO BIOL CELLULARE NEUROSCI 41041 1% 23% 30
3 CHEM GENOM CORE IL 36859 0% 52% 12
4 DIPARTIMENTO EMATOL ONCOL MED MOL 26847 0% 25% 18
5 IST CLIN PEDIAT 22232 0% 17% 22
6 PROGRAM SIGNAL TRANSDUCT 20076 0% 21% 16
7 EXCELLENCE CLIN TRIAL 18592 0% 14% 22
8 MEDCHEM 1 18400 0% 63% 5
9 IMMUNOL INNOVAT BASE POST EDUC GUIZHOU PROV 17667 0% 100% 3
10 INSERMUMR S1131 17667 0% 100% 3

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 25823 3% 3% 163
2 JOURNAL OF BIOLOGICAL CHEMISTRY 7426 9% 0% 455
3 MOLECULAR AND CELLULAR BIOLOGY 3598 2% 1% 120
4 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 3308 2% 0% 124
5 ONCOGENE 2841 2% 1% 97
6 AMERICAN JOURNAL OF MEDICAL GENETICS 2731 1% 1% 65
7 EUROPEAN JOURNAL OF MEDICAL GENETICS 2293 0% 2% 22
8 JOURNAL OF MEDICAL GENETICS 1384 1% 1% 38
9 CLINICAL DYSMORPHOLOGY 1285 0% 1% 16
10 CELLULAR SIGNALLING 1201 1% 1% 31

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 NOONAN SYNDROME 1961475 8% 82% 404 Search NOONAN+SYNDROME Search NOONAN+SYNDROME
2 PROTEIN TYROSINE PHOSPHATASE 1105320 8% 42% 452 Search PROTEIN+TYROSINE+PHOSPHATASE Search PROTEIN+TYROSINE+PHOSPHATASE
3 COSTELLO SYNDROME 806193 3% 93% 148 Search COSTELLO+SYNDROME Search COSTELLO+SYNDROME
4 PTPN11 593609 2% 81% 125 Search PTPN11 Search PTPN11
5 PTP1B 568516 4% 51% 188 Search PTP1B Search PTP1B
6 CARDIO FACIO CUTANEOUS SYNDROME 477619 2% 97% 84 Search CARDIO+FACIO+CUTANEOUS+SYNDROME Search CARDIO+FACIO+CUTANEOUS+SYNDROME
7 RASOPATHY 432846 2% 76% 97 Search RASOPATHY Search RASOPATHY
8 LEOPARD SYNDROME 408356 1% 88% 79 Search LEOPARD+SYNDROME Search LEOPARD+SYNDROME
9 SHP2 358547 2% 57% 107 Search SHP2 Search SHP2
10 PRL 3 353635 1% 88% 68 Search PRL+3 Search PRL+3

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 2


rank cluster_id2 link
1 3303 ACP1//ACYLPHOSPHATASE//TARTRATE RESISTANT ACID PHOSPHATASE
2 559 SH2 DOMAIN//BTK//P66SHC
3 3927 MIDKINE//PLEIOTROPHIN//HB GAM
4 1406 JNK//ERK5//COFFIN LOWRY SYNDROME
5 3153 THROMBOSPONDIN 1//THROMBOSPONDIN//CD47
6 1014 INSULIN RECEPTOR//GLUT4//GLYCOSYLPHOSPHATIDYLINOSITOL
7 911 STAT3//GP130//ONCOSTATIN M
8 2333 VANADIUM//VANADIUM COMPLEXES//VANADATE
9 1549 RAS//FARNESYLTRANSFERASE//RAL
10 2409 HEPATOCYTE GROWTH FACTOR//C MET//HGF

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