Class information for:
Level 2: CAMPTOTHECIN//SN 38//IRINOTECAN

Basic class information

Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes

The table includes all classes above and classes immediately below the current class.



Cluster id Level Cluster label #P
19 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 657099
496 3       FLUOROQUINOLONES//CAMPTOTHECIN//QUINOLONES 23115
1672 2             CAMPTOTHECIN//SN 38//IRINOTECAN 7132
763 1                   TOPOISOMERASE II//DNA TOPOISOMERASE II//DNA TOPOISOMERASE I 3119
3896 1                   CAMPTOTHECIN//TOPOTECAN//9 NITROCAMPTOTHECIN 1923
9538 1                   SN 38//IRINOTECAN//CPT 11 1177
12756 1                   CARBOXYLESTERASE//DRUG METAB BIOPHARMACEUT//CES1 913

Terms with highest relevance score



rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 CAMPTOTHECIN authKW 1077613 8% 43% 573
2 SN 38 authKW 542082 3% 65% 189
3 IRINOTECAN authKW 528496 7% 24% 495
4 TOPOISOMERASE I authKW 471996 3% 43% 246
5 TOPOTECAN authKW 413367 4% 33% 282
6 CPT 11 authKW 350561 2% 45% 178
7 TOPOISOMERASE II authKW 332201 3% 32% 232
8 CARBOXYLESTERASE authKW 226823 3% 27% 192
9 DNA TOPOISOMERASE I authKW 212382 1% 55% 88
10 TOPOISOMERASE I INHIBITOR authKW 195540 1% 51% 86

Web of Science journal categories



chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Oncology 25217 32% 0% 2267
2 Pharmacology & Pharmacy 9735 23% 0% 1653
3 Biochemistry & Molecular Biology 6547 28% 0% 1988
4 Chemistry, Medicinal 3816 8% 0% 537
5 Toxicology 926 4% 0% 298
6 Biophysics 650 5% 0% 324
7 Chemistry, Organic 581 6% 0% 409
8 Cell Biology 474 6% 0% 449
9 Genetics & Heredity 366 4% 0% 318
10 Biochemical Research Methods 207 3% 0% 199

Address terms



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 MOL PHARMACOL 50549 4% 4% 291
2 DANIEL DEN HOED KLIN 35328 0% 26% 31
3 DRUG METAB BIOPHARMACEUT 31794 0% 60% 12
4 STEHLIN FDN CANC 27600 0% 63% 10
5 BIOL PHARMACOL DNA TOPOISOMERASES 15773 0% 71% 5
6 PHARMACOGENOM MOL THER Y 13800 0% 63% 5
7 PURDUE CANC 13796 1% 8% 38
8 PEDIAT PHARMACOKINET THER EUT 13345 0% 17% 18
9 HEMATOL ONCOL DEV THER EUT SECT 13251 0% 100% 3
10 G MORUZZI BIOCHEM 12724 0% 41% 7

Journals



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 CANCER CHEMOTHERAPY AND PHARMACOLOGY 30613 3% 3% 229
2 ANTI-CANCER DRUGS 10554 1% 3% 90
3 CANCER RESEARCH 8776 4% 1% 286
4 BIOCHEMICAL PHARMACOLOGY 6986 2% 1% 175
5 CLINICAL CANCER RESEARCH 6694 2% 1% 155
6 INVESTIGATIONAL NEW DRUGS 5054 1% 2% 55
7 DRUG METABOLISM AND DISPOSITION 3769 1% 1% 82
8 MOLECULAR PHARMACOLOGY 3101 1% 1% 85
9 JOURNAL OF CLINICAL ONCOLOGY 2727 1% 1% 104
10 JOURNAL OF BIOLOGICAL CHEMISTRY 2408 4% 0% 316

Author Key Words



chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 CAMPTOTHECIN 1077613 8% 43% 573 Search CAMPTOTHECIN Search CAMPTOTHECIN
2 SN 38 542082 3% 65% 189 Search SN+38 Search SN+38
3 IRINOTECAN 528496 7% 24% 495 Search IRINOTECAN Search IRINOTECAN
4 TOPOISOMERASE I 471996 3% 43% 246 Search TOPOISOMERASE+I Search TOPOISOMERASE+I
5 TOPOTECAN 413367 4% 33% 282 Search TOPOTECAN Search TOPOTECAN
6 CPT 11 350561 2% 45% 178 Search CPT+11 Search CPT+11
7 TOPOISOMERASE II 332201 3% 32% 232 Search TOPOISOMERASE+II Search TOPOISOMERASE+II
8 CARBOXYLESTERASE 226823 3% 27% 192 Search CARBOXYLESTERASE Search CARBOXYLESTERASE
9 DNA TOPOISOMERASE I 212382 1% 55% 88 Search DNA+TOPOISOMERASE+I Search DNA+TOPOISOMERASE+I
10 TOPOISOMERASE I INHIBITOR 195540 1% 51% 86 Search TOPOISOMERASE+I+INHIBITOR Search TOPOISOMERASE+I+INHIBITOR

Core articles

The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 2



rank cluster_id2 link
1 3113 NUCLEAR MATRIX//SATB1//MATRIX ATTACHMENT REGION
2 942 FLUOROQUINOLONES//QUINOLONES//CIPROFLOXACIN
3 978 5 FLUOROURACIL//DIHYDROPYRIMIDINE DEHYDROGENASE//THYMIDINE PHOSPHORYLASE
4 812 P GLYCOPROTEIN//MULTIDRUG RESISTANCE//MDR1
5 1800 QUINOLINE//ACRIDINE//IMINO DIELS ALDER REACTION
6 2704 DUOCARMYCIN//ADEPT//MINOR GROOVE BINDER
7 2870 FHIT//WWOX//DIADENOSINE POLYPHOSPHATES
8 846 CARDIOTOXICITY//ANTHRACYCLINES//DOXORUBICIN
9 1497 CISPLATIN//ISOLATED LIMB PERFUSION//IFOSFAMIDE
10 4074 SURAMIN//3 DIMENSIONAL NEUROIMAGING//HT 29 D4 CELLS

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