Class information for:
Level 1: OXIDOSQUALENE CYCLASE//TRITERPENE SYNTHASE//SQUALENE HOPENE CYCLASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12077 933 33.6 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
680 3       HEVEA BRASILIENSIS//ISOPRENOID BIOSYNTHESIS//GUAYULE 8761
1585 2             ISOPRENOID BIOSYNTHESIS//ISOPRENOIDS//TERPENE SYNTHASE 7221
12077 1                   OXIDOSQUALENE CYCLASE//TRITERPENE SYNTHASE//SQUALENE HOPENE CYCLASE 933

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OXIDOSQUALENE CYCLASE authKW 1497567 6% 80% 57
2 TRITERPENE SYNTHASE authKW 558074 2% 95% 18
3 SQUALENE HOPENE CYCLASE authKW 484829 2% 74% 20
4 SQUALENE CYCLASE authKW 297513 1% 91% 10
5 BETA AMYRIN SYNTHASE authKW 267256 2% 58% 14
6 HOPENE authKW 251739 1% 77% 10
7 OXIDOSQUALENE authKW 251739 1% 77% 10
8 MERCURIC TRIFLATE authKW 209447 1% 80% 8
9 LANOSTEROL SYNTHASE authKW 181806 1% 56% 10
10 CYCLOARTENOL SYNTHASE authKW 178175 1% 78% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 4512 32% 0% 298
2 Chemistry, Medicinal 1696 13% 0% 123
3 Chemistry, Multidisciplinary 1163 25% 0% 230
4 Biochemistry & Molecular Biology 706 26% 0% 242
5 Plant Sciences 213 8% 0% 76
6 Biophysics 116 5% 0% 48
7 Pharmacology & Pharmacy 60 7% 0% 69
8 Mycology 48 1% 0% 10
9 Nutrition & Dietetics 35 2% 0% 21
10 Chemistry, Applied 22 2% 0% 21

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REACT ORGAN SELECT 36434 1% 16% 7
2 ANDALUZ BIL DESARROLLO 32727 0% 100% 1
3 BASES MOL AUTORENOUVELLEMENT SES ALTERAT GRP 32727 0% 100% 1
4 BIOL 2 AUF DER MORGENSTELLE 28 32727 0% 100% 1
5 BIOL ALLGEMEINE GENET 32727 0% 100% 1
6 BREAST HOSP 32727 0% 100% 1
7 CENT S 293 SHIMOMEGURO MEGURO KU 32727 0% 100% 1
8 CNRS UPR CHIM SUBST NAT 2301 32727 0% 100% 1
9 CVU STRATEGY OPERAT 32727 0% 100% 1
10 DIPARITMENTO SCI CHIM ALIMENTARI FARMACEUT FARM 32727 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ORGANIC LETTERS 4275 6% 0% 58
2 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2779 10% 0% 90
3 LIPIDS 1772 2% 0% 18
4 TETRAHEDRON LETTERS 1755 7% 0% 64
5 ORGANIC & BIOMOLECULAR CHEMISTRY 879 2% 0% 18
6 CHEMBIOCHEM 871 1% 0% 11
7 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 710 3% 0% 24
8 JOURNAL OF MEDICINAL CHEMISTRY 703 2% 0% 22
9 SYNLETT 643 2% 0% 17
10 PHYTOCHEMISTRY 618 2% 0% 21

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 OXIDOSQUALENE CYCLASE 1497567 6% 80% 57 Search OXIDOSQUALENE+CYCLASE Search OXIDOSQUALENE+CYCLASE
2 TRITERPENE SYNTHASE 558074 2% 95% 18 Search TRITERPENE+SYNTHASE Search TRITERPENE+SYNTHASE
3 SQUALENE HOPENE CYCLASE 484829 2% 74% 20 Search SQUALENE+HOPENE+CYCLASE Search SQUALENE+HOPENE+CYCLASE
4 SQUALENE CYCLASE 297513 1% 91% 10 Search SQUALENE+CYCLASE Search SQUALENE+CYCLASE
5 BETA AMYRIN SYNTHASE 267256 2% 58% 14 Search BETA+AMYRIN+SYNTHASE Search BETA+AMYRIN+SYNTHASE
6 HOPENE 251739 1% 77% 10 Search HOPENE Search HOPENE
7 OXIDOSQUALENE 251739 1% 77% 10 Search OXIDOSQUALENE Search OXIDOSQUALENE
8 MERCURIC TRIFLATE 209447 1% 80% 8 Search MERCURIC+TRIFLATE Search MERCURIC+TRIFLATE
9 LANOSTEROL SYNTHASE 181806 1% 56% 10 Search LANOSTEROL+SYNTHASE Search LANOSTEROL+SYNTHASE
10 CYCLOARTENOL SYNTHASE 178175 1% 78% 7 Search CYCLOARTENOL+SYNTHASE Search CYCLOARTENOL+SYNTHASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ABE, I , (2007) ENZYMATIC SYNTHESIS OF CYCLIC TRITERPENES.NATURAL PRODUCT REPORTS. VOL. 24. ISSUE 6. P. 1311 -1331 101 95% 77
2 WU, TK , CHANG, CH , LIU, YT , WANG, TT , (2008) SACCHAROMYCES CEREVISIAE OXIDOSQUALENE-LANOSTEROL CYCLASE: A CHEMISTRY-BIOLOGY INTERDISCIPLINARY STUDY OF THE PROTEIN'S STRUCTURE-FUNCTION-REACTION MECHANISM RELATIONSHIPS.CHEMICAL RECORD. VOL. 8. ISSUE 5. P. 302 -325 79 92% 23
3 ITO, R , MASUKAWA, Y , NAKADA, C , AMARI, K , NAKANO, C , HOSHINO, T , (2014) BETA-AMYRIN SYNTHASE FROM EUPHORBIA TIRUCALLI. STERIC BULK, NOT THE PI-ELECTRONS OF PHE, AT POSITION 474 HAS A KEY ROLE IN AFFORDING THE CORRECT FOLDING OF THE SUBSTRATE TO COMPLETE THE NORMAL POLYCYCLIZATION CASCADE.ORGANIC & BIOMOLECULAR CHEMISTRY. VOL. 12. ISSUE 23. P. 3836-3846 61 94% 0
4 THIMMAPPA, R , GEISLER, K , LOUVEAU, T , O'MAILLE, P , OSBOURN, A , (2014) TRITERPENE BIOSYNTHESIS IN PLANTS.ANNUAL REVIEW OF PLANT BIOLOGY, VOL 65. VOL. 65. ISSUE . P. 225 -257 79 50% 43
5 RACOLTA, S , JUHL, PB , SIRIM, D , PLEISS, J , (2012) THE TRITERPENE CYCLASE PROTEIN FAMILY: A SYSTEMATIC ANALYSIS.PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. VOL. 80. ISSUE 8. P. 2009 -2019 66 79% 12
6 HOSHINO, T , SATO, T , (2002) SQUALENE-HOPENE CYCLASE: CATALYTIC MECHANISM AND SUBSTRATE RECOGNITION.CHEMICAL COMMUNICATIONS. VOL. . ISSUE 4. P. 291-301 59 95% 103
7 XIONG, QB , ROCCO, F , WILSON, WK , XU, R , CERUTI, M , MATSUDA, SPT , (2005) STRUCTURE AND REACTIVITY OF THE DAMMARENYL CATION: CONFIGURATIONAL TRANSMISSION IN TRITERPENE SYNTHESIS.JOURNAL OF ORGANIC CHEMISTRY. VOL. 70. ISSUE 14. P. 5362-5375 74 74% 22
8 HOSHINO, T , MIYAHARA, Y , HANAOKA, M , TAKAHASHI, K , KANEKO, I , (2015) BETA -AMYRIN BIOSYNTHESIS: THE METHYL-30 GROUP OF (3S)-2,3-OXIDOSQUALENE IS MORE CRITICAL TO ITS CORRECT FOLDING TO GENERATE THE PENTACYCLIC SCAFFOLD THAN THE METHYL-24 GROUP.CHEMISTRY-A EUROPEAN JOURNAL. VOL. 21. ISSUE 44. P. 15769 -15784 43 96% 0
9 ABE, I , ROHMER, M , PRESTWICH, GD , (1993) ENZYMATIC CYCLIZATION OF SQUALENE AND OXIDOSQUALENE TO STEROLS AND TRITERPENES.CHEMICAL REVIEWS. VOL. 93. ISSUE 6. P. 2189-2206 58 85% 433
10 SHINOZAKI, J , HIRUTA, M , OKADA, T , MASUDA, K , (2016) MIGRATED HOPENE SYNTHASES FROM COLYSIS POTHIFOLIA AND IDENTIFICATION OF A MIGRATION SWITCH CONTROLLING THE NUMBER OF 1,2-HYDRIDE AND METHYL SHIFTS.CHEMBIOCHEM. VOL. 17. ISSUE 1. P. 65 -70 37 90% 2

Classes with closest relation at Level 1


Rank Class id link
1 24455 HOPANOIDS//BACTERIOHOPANEPOLYOLS//BACTERIOHOPANETETROL
2 6968 STEROL METHYLTRANSFERASE//STEROL C24 METHYLTRANSFERASE//ERGOSTEROL BIOSYNTHESIS
3 7013 TERPENE SYNTHASE//MONOTERPENE SYNTHASE//SESQUITERPENE SYNTHASE
4 19834 SQUALENE SYNTHASE//SQUALENE SYNTHASE INHIBITOR//ZARAGOZIC ACIDS
5 11346 POLYGODIAL//DRIMANE//SCLAREOL
6 33272 2 CHLOROGLYCIDIC ESTER//ALPHA CHLOROGLYCIDIC ESTER//1 ALKOXYCARBONLY 2 ALKOXY AZIRIDINES
7 36821 SIPHOLANES//1 ACETYLVINYL P NITROBENZOYLOXY//24 BETA METHYLCHOLASTA 1 8 14 22 25 PENTEN 3 ONE 5 ALPHA OL 1 1H INDOL 3 YL 2 3 DIHYDROXY 5 METHYL HEXANE
8 19642 BELAMCANDA CHINENSIS//IRIDACEAE//IRIDALS
9 18833 CHLOROSULFOLIPIDS//IODOCARBOCYCLIZATION//BROMOLACTONIZATION
10 28475 BISMUTHIII TRIFLATE//BISMUTH TRIFLATE//BISMUTHIII HALIDES

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