Class information for:
Level 1: OPIOID GROWTH FACTOR//OPIOID GROWTH FACTOR RECEPTOR//PRENATAL MORPHINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12347 912 38.7 65%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
440 3       NOCICEPTIN//OPIOID RECEPTORS//MORPHINE 26600
121 2             OPIOID RECEPTORS//MORPHINE//DELTA OPIOID RECEPTOR 24293
12347 1                   OPIOID GROWTH FACTOR//OPIOID GROWTH FACTOR RECEPTOR//PRENATAL MORPHINE 912

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OPIOID GROWTH FACTOR authKW 1406930 5% 98% 43
2 OPIOID GROWTH FACTOR RECEPTOR authKW 937447 3% 100% 28
3 PRENATAL MORPHINE authKW 714240 3% 89% 24
4 MET5 ENKEPHALIN authKW 491029 2% 67% 22
5 LOW DOSE NALTREXONE authKW 344365 1% 86% 12
6 PRENATAL MORPHINE EXPOSURE authKW 314335 1% 72% 13
7 NEURAL BEHAV SCI address 274022 7% 13% 65
8 ZETA OPIOID RECEPTOR authKW 234362 1% 100% 7
9 OGFR authKW 172183 1% 86% 6
10 OGF authKW 150658 1% 75% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 6480 49% 0% 447
2 Developmental Biology 1928 10% 0% 87
3 Pharmacology & Pharmacy 1164 23% 0% 206
4 Behavioral Sciences 786 7% 0% 64
5 Medicine, Research & Experimental 638 11% 0% 99
6 Endocrinology & Metabolism 135 6% 0% 54
7 Toxicology 102 4% 0% 36
8 Oncology 76 7% 0% 63
9 Physiology 43 3% 0% 31
10 Psychology, Biological 40 1% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEURAL BEHAV SCI 274022 7% 13% 65
2 ALBERT SZENT GYORGYI MED PHARMACEUT SCI 104612 1% 31% 10
3 HADASSAH MED MOLEC VIROL 66961 0% 100% 2
4 MASHHAD COGNIT NEUROSCI 66961 0% 100% 2
5 MILTON S HERSHEY MED 45906 7% 2% 66
6 ANESTHESIA CRIT CARE MEDMED 33480 0% 100% 1
7 BIOCHEM NARCOL 33480 0% 100% 1
8 CJF 9502 33480 0% 100% 1
9 COMPARAT MED TECHNOL UNIT 33480 0% 100% 1
10 CYTOGENET MOL MED 33480 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEVELOPMENTAL BRAIN RESEARCH 26442 7% 1% 63
2 NEUROBEHAVIORAL TOXICOLOGY 10496 0% 8% 4
3 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 5174 5% 0% 44
4 NEUROBEHAVIORAL TOXICOLOGY AND TERATOLOGY 4808 1% 2% 9
5 MINERVA GINECOLOGICA 3346 0% 10% 1
6 EXPERIMENTAL BIOLOGY AND MEDICINE 3241 2% 1% 16
7 BRAIN RESEARCH 3103 7% 0% 67
8 DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS 3037 1% 1% 8
9 BRAIN RESEARCH BULLETIN 2857 3% 0% 26
10 LIFE SCIENCES 2103 4% 0% 36

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 OPIOID GROWTH FACTOR 1406930 5% 98% 43 Search OPIOID+GROWTH+FACTOR Search OPIOID+GROWTH+FACTOR
2 OPIOID GROWTH FACTOR RECEPTOR 937447 3% 100% 28 Search OPIOID+GROWTH+FACTOR+RECEPTOR Search OPIOID+GROWTH+FACTOR+RECEPTOR
3 PRENATAL MORPHINE 714240 3% 89% 24 Search PRENATAL+MORPHINE Search PRENATAL+MORPHINE
4 MET5 ENKEPHALIN 491029 2% 67% 22 Search MET5+ENKEPHALIN Search MET5+ENKEPHALIN
5 LOW DOSE NALTREXONE 344365 1% 86% 12 Search LOW+DOSE+NALTREXONE Search LOW+DOSE+NALTREXONE
6 PRENATAL MORPHINE EXPOSURE 314335 1% 72% 13 Search PRENATAL+MORPHINE+EXPOSURE Search PRENATAL+MORPHINE+EXPOSURE
7 ZETA OPIOID RECEPTOR 234362 1% 100% 7 Search ZETA+OPIOID+RECEPTOR Search ZETA+OPIOID+RECEPTOR
8 OGFR 172183 1% 86% 6 Search OGFR Search OGFR
9 OGF 150658 1% 75% 6 Search OGF Search OGF
10 OPIOID GROWTH FACTOR OGF 139499 1% 83% 5 Search OPIOID+GROWTH+FACTOR+OGF Search OPIOID+GROWTH+FACTOR+OGF

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 ZAGON, IS , VERDERAME, MF , MCLAUGHLIN, PJ , (2002) THE BIOLOGY OF THE OPIOID GROWTH FACTOR RECEPTOR (OGFR).BRAIN RESEARCH REVIEWS. VOL. 38. ISSUE 3. P. 351-376 97 72% 165
2 MCLAUGHLIN, PJ , ZAGON, IS , (2012) THE OPIOID GROWTH FACTOR-OPIOID GROWTH FACTOR RECEPTOR AXIS: HOMEOSTATIC REGULATOR OF CELL PROLIFERATION AND ITS IMPLICATIONS FOR HEALTH AND DISEASE.BIOCHEMICAL PHARMACOLOGY. VOL. 84. ISSUE 6. P. 746 -755 60 88% 19
3 ZAGON, IS , DONAHUE, R , MCLAUGHLIN, PJ , (2013) TARGETING THE OPIOID GROWTH FACTOR: OPIOID GROWTH FACTOR RECEPTOR AXIS FOR TREATMENT OF HUMAN OVARIAN CANCER.EXPERIMENTAL BIOLOGY AND MEDICINE. VOL. 238. ISSUE 5. P. 579 -587 61 85% 5
4 MCLAUGHLIN, PJ , ZAGON, IS , (2015) DURATION OF OPIOID RECEPTOR BLOCKADE DETERMINES BIOTHERAPEUTIC RESPONSE.BIOCHEMICAL PHARMACOLOGY. VOL. 97. ISSUE 3. P. 236 -246 54 71% 3
5 ZAGON, IS , MCLAUGHLIN, PJ , (2014) OPIOID GROWTH FACTOR AND THE TREATMENT OF HUMAN PANCREATIC CANCER: A REVIEW.WORLD JOURNAL OF GASTROENTEROLOGY. VOL. 20. ISSUE 9. P. 2218-2223 35 90% 5
6 DONAHUE, RN , MCLAUGHLIN, PJ , ZAGON, IS , (2011) LOW-DOSE NALTREXONE TARGETS THE OPIOID GROWTH FACTOR-OPIOID GROWTH FACTOR RECEPTOR PATHWAY TO INHIBIT CELL PROLIFERATION: MECHANISTIC EVIDENCE FROM A TISSUE CULTURE MODEL.EXPERIMENTAL BIOLOGY AND MEDICINE. VOL. 236. ISSUE 9. P. 1036-1050 39 80% 11
7 CHENG, F , MCLAUGHLIN, PJ , VERDERAME, MF , ZAGON, IS , (2009) THE OGF-OGFR AXIS UTILIZES THE P16(INK4A) AND P21(WAF1/CIP1) PATHWAYS TO RESTRICT NORMAL CELL PROLIFERATION.MOLECULAR BIOLOGY OF THE CELL. VOL. 20. ISSUE 1. P. 319-327 37 82% 24
8 ZAGON, IS , DONAHUE, RN , MCLAUGHLIN, PJ , (2009) OPIOID GROWTH FACTOR-OPIOID GROWTH FACTOR RECEPTOR AXIS IS A PHYSIOLOGICAL DETERMINANT OF CELL PROLIFERATION IN DIVERSE HUMAN CANCERS.AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. VOL. 297. ISSUE 4. P. R1154-R1161 42 71% 16
9 MCLAUGHLIN, PJ , KEIPER, CL , VERDERAME, MF , ZAGON, IS , (2012) TARGETED OVEREXPRESSION OF OGFR IN EPITHELIUM OF TRANSGENIC MICE SUPPRESSES CELL PROLIFERATION AND IMPAIRS FULL-THICKNESS WOUND CLOSURE.AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. VOL. 302. ISSUE 9. P. R1084-R1090 30 91% 3
10 SASSANI, JW , ZAGON, IS , MCLAUGHLIN, PJ , (2003) OPIOID GROWTH FACTOR MODULATION OF CORNEAL EPITHELIUM: UPPERS AND DOWNERS.CURRENT EYE RESEARCH. VOL. 26. ISSUE 5. P. 249-262 48 71% 12

Classes with closest relation at Level 1


Rank Class id link
1 12122 NEONATAL ABSTINENCE SYNDROME//METHADONE//BUPRENORPHINE
2 12128 PROENKEPHALIN//MET ENKEPHALIN ARG6 PHE7//ENKEPHALIN PRECURSORS
3 5268 METHIONINE ENKEPHALIN//MORPHINE//BETA ENDORPHIN
4 5552 MU OPIOID RECEPTOR//OPIOID RECEPTORS//OPIOID TOLERANCE
5 26800 DADLE//HIBERNATION INDUCTION TRIGGER//DELTA OPIOID RECEPTOR
6 23186 CORNEAL AUTOFLUORESCENCE//DIABETIC CORNEA//DIABETIC KERATOPATHY
7 20261 SEMINOL CLIN EMBRYOL//NALOXONE BINDING SITE//NURSERY 2
8 24401 HYPOXIC SURVIVAL//AFTER SUPPRESSION//AIRTIGHT CHAMBER
9 3821 DYNORPHIN//DYNORPHIN A//KAPPA OPIOID RECEPTOR
10 27445 GDH PROMOTER//160 KDA NEUROFILAMENT PROTEIN//ASTROCYTE CULTURES MICRODIALYSIS

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