Class information for:
Level 1: OPIOID INDUCED HYPERALGESIA//MORPHINE TOLERANCE//MORPHINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12725 885 42.8 82%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
440 3       NOCICEPTIN//OPIOID RECEPTORS//MORPHINE 26600
121 2             OPIOID RECEPTORS//MORPHINE//DELTA OPIOID RECEPTOR 24293
12725 1                   OPIOID INDUCED HYPERALGESIA//MORPHINE TOLERANCE//MORPHINE 885

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OPIOID INDUCED HYPERALGESIA authKW 969375 5% 59% 48
2 MORPHINE TOLERANCE authKW 210799 4% 17% 37
3 MORPHINE authKW 175665 22% 3% 191
4 OPIOID TOLERANCE authKW 144815 3% 18% 23
5 HYPERALGESIA authKW 141324 12% 4% 107
6 LY 235959 authKW 116207 1% 42% 8
7 ANTINOCICEPTIVE TOLERANCE authKW 112698 1% 47% 7
8 MORPHIDEX R authKW 103505 0% 100% 3
9 OPIOID DEPENDENCE TOLERANCE authKW 103505 0% 100% 3
10 NMDA RECEPTOR ANTAGONIST authKW 97777 4% 8% 36

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Anesthesiology 18565 28% 0% 244
2 Neurosciences 4116 40% 0% 356
3 Pharmacology & Pharmacy 2771 34% 0% 298
4 Clinical Neurology 789 14% 0% 126
5 Behavioral Sciences 683 7% 0% 59
6 Substance Abuse 256 3% 0% 24
7 Psychiatry 214 7% 0% 59
8 Medicine, Research & Experimental 36 4% 0% 32
9 Medicine, General & Internal 36 5% 0% 42
10 Health Care Sciences & Services 16 1% 0% 12

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TEAM HOMEOSTASIE ALLOSTASIE PATHOL REHABIL 77627 0% 75% 3
2 CNRSUMR 5227 69004 0% 100% 2
3 EQUIPE HOMEOSTASIE ALLOSTASIE PATHOL REHABIL 69004 0% 100% 2
4 HOMEOSTASIE ALLOSTASIE PATHOL 61332 0% 44% 4
5 BIOPSYCHOL DOCTORAL PROGRAM 57496 1% 33% 5
6 PHARMACEUT PHARMACODYNAM MC 865 41066 1% 24% 5
7 ANAESTHESIA ULLEVAAL 34502 0% 100% 1
8 ANALGESIA INTENS CARE UNIT 34502 0% 100% 1
9 ANESTHESIA CRIT CARE PAIN MED TRANSLAT 34502 0% 100% 1
10 ANESTHESIA CRIT CARENEURAL PLAST GRP 34502 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PAIN 10988 6% 1% 50
2 ANESTHESIOLOGY 5114 5% 0% 41
3 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 4401 5% 0% 40
4 JOURNAL OF PAIN 4224 2% 1% 15
5 ANESTHESIA AND ANALGESIA 4121 5% 0% 42
6 EUROPEAN JOURNAL OF PHARMACOLOGY 2891 6% 0% 49
7 DOULEUR ET ANALGESIE 2633 0% 2% 4
8 PAIN MEDICINE 2525 1% 1% 12
9 PAIN PHYSICIAN 2217 1% 1% 8
10 BRAIN RESEARCH 1759 6% 0% 50

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 OPIOID INDUCED HYPERALGESIA 969375 5% 59% 48 Search OPIOID+INDUCED+HYPERALGESIA Search OPIOID+INDUCED+HYPERALGESIA
2 MORPHINE TOLERANCE 210799 4% 17% 37 Search MORPHINE+TOLERANCE Search MORPHINE+TOLERANCE
3 MORPHINE 175665 22% 3% 191 Search MORPHINE Search MORPHINE
4 OPIOID TOLERANCE 144815 3% 18% 23 Search OPIOID+TOLERANCE Search OPIOID+TOLERANCE
5 HYPERALGESIA 141324 12% 4% 107 Search HYPERALGESIA Search HYPERALGESIA
6 LY 235959 116207 1% 42% 8 Search LY+235959 Search LY+235959
7 ANTINOCICEPTIVE TOLERANCE 112698 1% 47% 7 Search ANTINOCICEPTIVE+TOLERANCE Search ANTINOCICEPTIVE+TOLERANCE
8 MORPHIDEX R 103505 0% 100% 3 Search MORPHIDEX+R Search MORPHIDEX+R
9 OPIOID DEPENDENCE TOLERANCE 103505 0% 100% 3 Search OPIOID+DEPENDENCE+TOLERANCE Search OPIOID+DEPENDENCE+TOLERANCE
10 NMDA RECEPTOR ANTAGONIST 97777 4% 8% 36 Search NMDA+RECEPTOR+ANTAGONIST Search NMDA+RECEPTOR+ANTAGONIST

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 LEE, M , SILVERMAN, S , HANSEN, H , PATEL, V , MANCHIKANTI, L , (2011) A COMPREHENSIVE REVIEW OF OPIOID-INDUCED HYPERALGESIA.PAIN PHYSICIAN. VOL. 14. ISSUE 2. P. 145 -161 70 38% 204
2 KIM, SH , STOICEA, N , SOGHOMONYAN, S , BERGESE, SD , (2014) LNTRAOPERATIVE USE OF REMIFENTANIL AND OPIOID INDUCED HYPERALGESIA/ACUTE OPIOID TOLERANCE: SYSTEMATIC REVIEW.FRONTIERS IN PHARMACOLOGY. VOL. 5. ISSUE . P. - 51 62% 26
3 ANGST, MS , CLARK, JD , (2006) OPIOID-INDUCED HYPERALGESIA - A QUALITATIVE SYSTEMATIC REVIEW.ANESTHESIOLOGY. VOL. 104. ISSUE 3. P. 570-587 67 41% 459
4 KIM, SH , STOICEA, N , SOGHOMONYAN, S , BERGESE, SD , (2015) REMIFENTANIL-ACUTE OPIOID TOLERANCE AND OPIOID-INDUCED HYPERALGESIA: A SYSTEMATIC REVIEW.AMERICAN JOURNAL OF THERAPEUTICS. VOL. 22. ISSUE 3. P. E62 -E74 55 60% 3
5 FISHBAIN, DA , COLE, B , LEWIS, JE , GAO, JR , ROSOMOFF, RS , (2009) DO OPIOIDS INDUCE HYPERALGESIA IN HUMANS? AN EVIDENCE-BASED STRUCTURED REVIEW.PAIN MEDICINE. VOL. 10. ISSUE 5. P. 829 -839 43 72% 70
6 FLETCHER, D , MARTINEZ, V , (2014) OPIOID-INDUCED HYPERALGESIA IN PATIENTS AFTER SURGERY: A SYSTEMATIC REVIEW AND A META-ANALYSIS.BRITISH JOURNAL OF ANAESTHESIA. VOL. 112. ISSUE 6. P. 991-1004 31 69% 47
7 CHU, LF , ANGST, MS , CLARK, D , (2008) OPIOID-INDUCED HYPERALGESIA IN HUMANS - MOLECULAR MECHANISMS AND CLINICAL CONSIDERATIONS.CLINICAL JOURNAL OF PAIN. VOL. 24. ISSUE 6. P. 479-496 61 37% 204
8 AROUT, CA , EDENS, E , PETRAKIS, IL , SOFUOGLU, M , (2015) TARGETING OPIOID-INDUCED HYPERALGESIA IN CLINICAL TREATMENT: NEUROBIOLOGICAL CONSIDERATIONS.CNS DRUGS. VOL. 29. ISSUE 6. P. 465 -486 73 33% 5
9 LABOUREYRAS, E , AUBRUN, F , MONSAINGEON, M , CORCUFF, JB , LAULIN, JP , SIMONNET, G , (2014) EXOGENOUS AND ENDOGENOUS OPIOID-INDUCED PAIN HYPERSENSITIVITY IN DIFFERENT RAT STRAINS.PAIN RESEARCH & MANAGEMENT. VOL. 19. ISSUE 4. P. 191 -197 34 76% 4
10 YU, EHY , TRAN, DHD , LAM, SW , IRWIN, MG , (2016) REMIFENTANIL TOLERANCE AND HYPERALGESIA: SHORT-TERM GAIN, LONG-TERM PAIN?.ANAESTHESIA. VOL. 71. ISSUE 11. P. 1347 -1362 41 57% 1

Classes with closest relation at Level 1


Rank Class id link
1 8851 MORPHINE WITHDRAWAL//ACUTE DEPENDENCE//MORPHINE DEPENDENCE
2 5552 MU OPIOID RECEPTOR//OPIOID RECEPTORS//OPIOID TOLERANCE
3 11383 KETAMINE//S KETAMINE//NORKETAMINE
4 17887 REMIFENTANIL//ANALGESICS OPIOID REMIFENTANIL//ANALGESICS REMIFENTANIL
5 17688 DEXTROMETHORPHAN//COUGH AND COLD MEDICATIONS//DIMEMORFAN
6 14997 GRP NEUROFARMACOL MOL//PERIPHERAL ANTINOCICEPTION//ANTINOCICEPTION
7 2715 DORSAL HORN//SPINAL CORD GRP//SUBSTANTIA GELATINOSA
8 1457 NEUROPATHIC PAIN//HYPERALGESIA//CHRONIC CONSTRICTION INJURY
9 1265 OPIOIDS//CHRONIC NONCANCER PAIN//PRESCRIPTION OPIOIDS
10 28663 INTRATHECAL MIDAZOLAM//MIDAZOLAM//A DELTA FIBER EVOKED RESPONSE

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