Class information for:
Level 1: MORPHINE WITHDRAWAL//ACUTE DEPENDENCE//MORPHINE DEPENDENCE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8851 1211 40.3 66%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
440 3       NOCICEPTIN//OPIOID RECEPTORS//MORPHINE 26600
121 2             OPIOID RECEPTORS//MORPHINE//DELTA OPIOID RECEPTOR 24293
8851 1                   MORPHINE WITHDRAWAL//ACUTE DEPENDENCE//MORPHINE DEPENDENCE 1211

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MORPHINE WITHDRAWAL authKW 1294364 9% 48% 107
2 ACUTE DEPENDENCE authKW 350068 2% 73% 19
3 MORPHINE DEPENDENCE authKW 304798 4% 26% 46
4 EQUIP CELLULAR MOL PHARMACOL address 302561 1% 100% 12
5 OPIATE WITHDRAWAL authKW 264423 3% 27% 39
6 MORPHINE authKW 250876 22% 4% 267
7 BUTORPHANOL DEPENDENCE authKW 201707 1% 100% 8
8 NORADRENALINE TURNOVER authKW 190057 1% 54% 14
9 CONDITIONED PLACE AVERSION authKW 154908 2% 24% 26
10 WITHDRAWAL authKW 146905 10% 5% 116

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 10640 54% 0% 656
2 Pharmacology & Pharmacy 10519 54% 0% 655
3 Behavioral Sciences 2099 10% 0% 118
4 Psychiatry 1583 14% 0% 168
5 Substance Abuse 754 4% 0% 47
6 Medicine, Research & Experimental 124 5% 0% 60
7 Physiology 23 3% 0% 31
8 Chemistry, Medicinal 5 1% 0% 17
9 Psychology, Biological 4 0% 0% 4
10 Anesthesiology 3 1% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EQUIP CELLULAR MOL PHARMACOL 302561 1% 100% 12
2 GRP CELLULAR MOL PHARMACOL 107570 1% 53% 8
3 GRP PROGRAM NEUROSCI 90045 0% 71% 5
4 CSV ARRIXACA HOSP 50427 0% 100% 2
5 MED MOLEC PSYCHIAT 50427 0% 100% 2
6 MED PSYCHIAT 34 PK ST 50427 0% 100% 2
7 NEUROPSYCHOBIOL DESAD TAT 44218 1% 18% 10
8 GRP INFLAMMAT 33617 0% 67% 2
9 ANESTHESIOL 125 3550 LA JOLLA VILLAGE DR 25213 0% 100% 1
10 CALIF MED PHARMACOL 25213 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PSYCHOPHARMACOLOGY 13975 7% 1% 82
2 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 11981 6% 1% 77
3 EUROPEAN JOURNAL OF PHARMACOLOGY 7851 8% 0% 94
4 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 4831 5% 0% 64
5 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 3459 2% 0% 29
6 NEUROPSYCHOPHARMACOLOGY 3322 2% 1% 26
7 SYNAPSE 3043 2% 1% 20
8 BRAIN RESEARCH 2827 6% 0% 74
9 ADDICTION BIOLOGY 2546 1% 1% 11
10 CHINESE STUDIES IN PHILOSOPHY 2520 0% 10% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MORPHINE WITHDRAWAL 1294364 9% 48% 107 Search MORPHINE+WITHDRAWAL Search MORPHINE+WITHDRAWAL
2 ACUTE DEPENDENCE 350068 2% 73% 19 Search ACUTE+DEPENDENCE Search ACUTE+DEPENDENCE
3 MORPHINE DEPENDENCE 304798 4% 26% 46 Search MORPHINE+DEPENDENCE Search MORPHINE+DEPENDENCE
4 OPIATE WITHDRAWAL 264423 3% 27% 39 Search OPIATE+WITHDRAWAL Search OPIATE+WITHDRAWAL
5 MORPHINE 250876 22% 4% 267 Search MORPHINE Search MORPHINE
6 BUTORPHANOL DEPENDENCE 201707 1% 100% 8 Search BUTORPHANOL+DEPENDENCE Search BUTORPHANOL+DEPENDENCE
7 NORADRENALINE TURNOVER 190057 1% 54% 14 Search NORADRENALINE+TURNOVER Search NORADRENALINE+TURNOVER
8 CONDITIONED PLACE AVERSION 154908 2% 24% 26 Search CONDITIONED+PLACE+AVERSION Search CONDITIONED+PLACE+AVERSION
9 WITHDRAWAL 146905 10% 5% 116 Search WITHDRAWAL Search WITHDRAWAL
10 NALOXONE PRECIPITATED WITHDRAWAL 139630 1% 46% 12 Search NALOXONE+PRECIPITATED+WITHDRAWAL Search NALOXONE+PRECIPITATED+WITHDRAWAL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MALDONADO, R , (1997) PARTICIPATION OF NORADRENERGIC PATHWAYS IN THE EXPRESSION OF OPIATE WITHDRAWAL: BIOCHEMICAL AND PHARMACOLOGICAL EVIDENCE.NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. VOL. 21. ISSUE 1. P. 91-104 70 77% 149
2 HARRIS, AC , GEWIRTZ, JC , (2005) ACUTE OPIOID DEPENDENCE: CHARACTERIZING THE EARLY ADAPTATIONS UNDERLYING DRUG WITHDRAWAL.PSYCHOPHARMACOLOGY. VOL. 178. ISSUE 4. P. 353-366 64 50% 26
3 MANNELLI, P , GOTTHEIL, E , PEOPLES, JF , OROPEZA, VC , VAN BOCKSTAELE, EJ , (2004) CHRONIC VERY LOW DOSE NALTREXONE ADMINISTRATION ATTENUATES OPIOID WITHDRAWAL EXPRESSION.BIOLOGICAL PSYCHIATRY. VOL. 56. ISSUE 4. P. 261-268 49 64% 14
4 KAEIDI, A , AZIZI, H , JAVAN, M , SOLEIMANI, SMA , FATHOLLAHI, Y , SEMNANIAN, S , (2015) DIRECT FACILITATORY ROLE OF PARAGIGANTOCELLULARIS NEURONS IN OPIATE WITHDRAWAL-INDUCED HYPERACTIVITY OF RAT LOCUS COERULEUS NEURONS: AN IN VITRO STUDY.PLOS ONE. VOL. 10. ISSUE 7. P. - 27 82% 0
5 VAN BOCKSTAELE, EJ , RUDOY, C , MANNELLI, P , OROPEZA, V , QIAN, Y , (2006) ELEVATED MU-OPIOID RECEPTOR EXPRESSION IN THE NUCLEUS OF THE SOLITARY TRACT ACCOMPANIES ATTENUATED WITHDRAWAL SIGNS AFTER CHRONIC LOW DOSE NALTREXONE IN OPIATE-DEPENDENT RATS.JOURNAL OF NEUROSCIENCE RESEARCH. VOL. 83. ISSUE 3. P. 508-514 42 60% 7
6 VAN BOCKSTAELE, EJ , MENKO, AS , DROLET, G , (2001) NEUROADAPTIVE RESPONSES IN BRAINSTEM NORADRENERGIC NUCLEI FOLLOWING CHRONIC MORPHINE EXPOSURE.MOLECULAR NEUROBIOLOGY. VOL. 23. ISSUE 2-3. P. 155-171 45 60% 27
7 CRINER, SH , LIU, J , SCHULTEIS, G , (2007) RAPID NEUROADAPTATION IN THE NUCLEUS ACCUMBENS AND BED NUCLEUS OF THE STRIA TERMINALIS MEDIATES SUPPRESSION OF OPERANT RESPONDING DURING WITHDRAWAL FROM ACUTE OPIOID DEPENDENCE.NEUROSCIENCE. VOL. 144. ISSUE 4. P. 1436-1446 34 67% 7
8 SINCHAISUK, S , HO, IK , ROCKHOLD, RW , (2002) FOCAL KAPPA-OPIOID RECEPTOR-MEDIATED DEPENDENCE AND WITHDRAWAL IN THE NUCLEUS PARAGIGANTOCELLULARIS.PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. VOL. 74. ISSUE 1. P. 241-252 29 88% 4
9 MAZEI-ROBISON, MS , NESTLER, EJ , (2012) OPIATE-INDUCED MOLECULAR AND CELLULAR PLASTICITY OF VENTRAL TEGMENTAL AREA AND LOCUS COERULEUS CATECHOLAMINE NEURONS.COLD SPRING HARBOR PERSPECTIVES IN MEDICINE. VOL. 2. ISSUE 7. P. - 40 43% 27
10 VAN BOCKSTAELE, EJ , QIAN, YP , STERLING, RC , PAGE, ME , (2008) LOW DOSE NALTREXONE ADMINISTRATION IN MORPHINE DEPENDENT RATS ATTENUATES WITHDRAWAL-INDUCED NOREPINEPHRINE EFFLUX IN FOREBRAIN.PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. VOL. 32. ISSUE 4. P. 1048-1056 31 66% 10

Classes with closest relation at Level 1


Rank Class id link
1 12725 OPIOID INDUCED HYPERALGESIA//MORPHINE TOLERANCE//MORPHINE
2 5552 MU OPIOID RECEPTOR//OPIOID RECEPTORS//OPIOID TOLERANCE
3 22871 DUODENAL DISTENSION//KATEDRA FIZJOL BIOCHEM FARMAKOL TOKSYKOL//EXPT CLIN PHYSIOPHARMACOL
4 6765 KAPPA OPIOID RECEPTOR//BIOL ADDICT DIS//DYNORPHIN
5 12818 LOFEXIDINE//NALTREXONE//6 BETA NALTREXOL
6 22769 CONDITIONED PLACE PREFERENCE//DIETHYLPROPION//DOPAMINE RECEPTOR SUPERSENSITIVITY
7 33462 DELTA FOSB//FISHBERG NEUROSCI//FOSB
8 36873 STRAUB TAIL REACTION//BEIGE J MICE//MU2 OPIOID RECEPTOR
9 24601 PUSH PULL SUPERFUSION//PUSH PULL CANNULA//RU24722
10 24511 TAIL FLICK INHIBITION//DIPARTIMENTO SCI FARMACOBIOL COMPLESSO NINI BARBI//DIALKYLAMINOALKYLNAPHTHALENES

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