Class information for:
Level 1: NEURAL TUBE DEFECTS//FOLIC ACID//ANENCEPHALY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1292 2736 35.3 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
502 3       HOMOCYSTEINE//FOLATE//FOLIC ACID 22046
254 2             HOMOCYSTEINE//FOLATE//FOLIC ACID 19695
1292 1                   NEURAL TUBE DEFECTS//FOLIC ACID//ANENCEPHALY 2736

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEURAL TUBE DEFECTS authKW 3345193 25% 43% 692
2 FOLIC ACID authKW 1217137 22% 18% 605
3 ANENCEPHALY authKW 441104 4% 36% 110
4 BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY journal 409904 8% 17% 216
5 FOLATE authKW 307407 11% 9% 310
6 SPINA BIFIDA authKW 272412 7% 14% 179
7 BIRTH DEFECTS authKW 186027 5% 13% 129
8 CHILD HLTH EPIDEMIOL address 128649 1% 82% 14
9 BIRTH DEFECTS DEV DISABIL address 117380 4% 10% 108
10 FOLIC ACID SUPPLEMENTATION authKW 116611 1% 37% 28

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Developmental Biology 8608 12% 0% 316
2 Nutrition & Dietetics 8001 15% 0% 402
3 Obstetrics & Gynecology 7302 16% 0% 442
4 Toxicology 4049 12% 0% 331
5 Public, Environmental & Occupational Health 3187 15% 0% 410
6 Pediatrics 2314 11% 0% 297
7 Genetics & Heredity 2182 13% 0% 353
8 Medicine, General & Internal 1309 12% 0% 316
9 Reproductive Biology 700 3% 0% 95
10 Medical Laboratory Technology 75 1% 0% 31

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHILD HLTH EPIDEMIOL 128649 1% 82% 14
2 BIRTH DEFECTS DEV DISABIL 117380 4% 10% 108
3 MOL PATHOGENESIS SECT 75421 0% 52% 13
4 ENVIRONM GENET MED 71381 1% 27% 24
5 BIRTH DEFECTS EPIDEMIOL SURVEILLANCE BRANCH 65165 1% 19% 30
6 CALIF BIRTH DEFECTS MONITORING PROGRAM 48830 1% 24% 18
7 MARCH DIMES BIRTH DEFECTS FDN 44993 0% 37% 11
8 EUROCAT REGISTRAT 39850 0% 71% 5
9 CHILD HLTH EPIDEMIOL UNIT 37578 0% 42% 8
10 WHO ABORATING REPROD HLTH POPULAT S 36514 0% 55% 6

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY 409904 8% 17% 216
2 TERATOLOGY 19337 2% 3% 58
3 PAEDIATRIC AND PERINATAL EPIDEMIOLOGY 7620 1% 2% 30
4 AMERICAN JOURNAL OF MEDICAL GENETICS 5793 2% 1% 68
5 PUBLIC HEALTH NUTRITION 4746 1% 1% 39
6 AMERICAN JOURNAL OF CLINICAL NUTRITION 3094 2% 0% 61
7 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 2877 1% 1% 39
8 FOOD AND NUTRITION BULLETIN 2594 0% 2% 13
9 REPRODUCTIVE TOXICOLOGY 2518 1% 1% 24
10 JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE 2391 1% 1% 30

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NEURAL TUBE DEFECTS 3345193 25% 43% 692 Search NEURAL+TUBE+DEFECTS Search NEURAL+TUBE+DEFECTS
2 FOLIC ACID 1217137 22% 18% 605 Search FOLIC+ACID Search FOLIC+ACID
3 ANENCEPHALY 441104 4% 36% 110 Search ANENCEPHALY Search ANENCEPHALY
4 FOLATE 307407 11% 9% 310 Search FOLATE Search FOLATE
5 SPINA BIFIDA 272412 7% 14% 179 Search SPINA+BIFIDA Search SPINA+BIFIDA
6 BIRTH DEFECTS 186027 5% 13% 129 Search BIRTH+DEFECTS Search BIRTH+DEFECTS
7 FOLIC ACID SUPPLEMENTATION 116611 1% 37% 28 Search FOLIC+ACID+SUPPLEMENTATION Search FOLIC+ACID+SUPPLEMENTATION
8 HOMOCYSTEINE 87776 8% 4% 222 Search HOMOCYSTEINE Search HOMOCYSTEINE
9 FORTIFICATION 84974 3% 11% 71 Search FORTIFICATION Search FORTIFICATION
10 RED BLOOD CELL FOLATE 78444 1% 47% 15 Search RED+BLOOD+CELL+FOLATE Search RED+BLOOD+CELL+FOLATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 IMBARD, A , BENOIST, JF , BLOM, HJ , (2013) NEURAL TUBE DEFECTS, FOLIC ACID AND METHYLATION.INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. VOL. 10. ISSUE 9. P. 4352-4389 193 84% 19
2 TAMURA, T , PICCIANO, MF , (2006) FOLATE AND HUMAN REPRODUCTION.AMERICAN JOURNAL OF CLINICAL NUTRITION. VOL. 83. ISSUE 5. P. 993-1016 159 52% 188
3 ATTA, CAM , FIEST, KM , FROLKIS, AD , JETTE, N , PRINGSHEIM, T , ST GERMAINE-SMITH, C , RAJAPAKSE, T , KAPLAN, GG , METCALFE, A , (2016) GLOBAL BIRTH PREVALENCE OF SPINA BIFIDA BY FOLIC ACID FORTIFICATION STATUS: A SYSTEMATIC REVIEW AND META-ANALYSIS.AMERICAN JOURNAL OF PUBLIC HEALTH. VOL. 106. ISSUE 1. P. E24 -E34 110 65% 2
4 ATTA, CAM , FIEST, KM , FROLKIS, AD , JETTE, N , PRINGSHEIM, T , ST GERMAINE-SMITH, C , RAJAPAKSE, T , KAPLAN, GG , METCALFE, A , (2016) GLOBAL BIRTH PREVALENCE OF SPINA BIFIDA BY FOLIC ACID FORTIFICATION STATUS: A SYSTEMATIC REVIEW AND META-ANALYSIS.AMERICAN JOURNAL OF PUBLIC HEALTH. VOL. 106. ISSUE 1. P. 159 -165 112 66% 0
5 BORTOLUS, R , BLOM, F , FILIPPINI, F , VAN POPPEL, MNM , LEONCINI, E , DE SMIT, DJ , BENETOLLO, PP , CORNEL, MC , DE WALLE, HEK , MASTROIACOVO, P , (2014) PREVENTION OF CONGENITAL MALFORMATIONS AND OTHER ADVERSE PREGNANCY OUTCOMES WITH 4.0 MG OF FOLIC ACID: COMMUNITY-BASED RANDOMIZED CLINICAL TRIAL IN ITALY AND THE NETHERLANDS.BMC PREGNANCY AND CHILDBIRTH. VOL. 14. ISSUE . P. - 79 68% 10
6 MOLLOY, AM , BRODY, LC , MILLS, JL , SCOTT, JM , KIRKE, PN , (2009) THE SEARCH FOR GENETIC POLYMORPHISMS IN THE HOMOCYSTEINE/FOLATE PATHWAY THAT CONTRIBUTE TO THE ETIOLOGY OF HUMAN NEURAL TUBE DEFECTS.BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY. VOL. 85. ISSUE 4. P. 285 -294 80 71% 36
7 CHEN, CP , (2008) SYNDROMES, DISORDERS AND MATERNAL RISK FACTORS ASSOCIATED WITH NEURAL TUBE DEFECTS (IV).TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY. VOL. 47. ISSUE 2. P. 141-150 79 75% 8
8 DE-REGIL, LM , PENA-ROSAS, JP , FERNANDEZ-GAXIOLA, AC , RAYCO-SOLON, P , (2015) EFFECTS AND SAFETY OF PERICONCEPTIONAL ORAL FOLATE SUPPLEMENTATION FOR PREVENTING BIRTH DEFECTS.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 12. P. - 86 55% 3
9 ZAGANJOR, I , SEKKARIE, A , TSANG, BL , WILLIAMS, J , RAZZAGHI, H , MULINARE, J , SNIEZEK, JE , CANNON, MJ , ROSENTHAL, J , (2016) DESCRIBING THE PREVALENCE OF NEURAL TUBE DEFECTS WORLDWIDE: A SYSTEMATIC LITERATURE REVIEW.PLOS ONE. VOL. 11. ISSUE 4. P. - 54 89% 0
10 YADAV, U , KUMAR, P , YADAV, SK , MISHRA, OP , RAI, V , (2015) "POLYMORPHISMS IN FOLATE METABOLISM GENES AS MATERNAL RISK FACTOR FOR NEURAL TUBE DEFECTS: AN UPDATED META-ANALYSIS".METABOLIC BRAIN DISEASE. VOL. 30. ISSUE 1. P. 7 -24 59 73% 4

Classes with closest relation at Level 1


Rank Class id link
1 23733 PRECONCEPTION CARE//PRECONCEPTION HEALTH//PRECONCEPTION
2 29068 BIRTH CERTIFICATES//HOSPITAL BIRTH RECORDS//MCH EPIDEMIOLOGY
3 8151 FOLATE//FOLIC ACID//FOOD FOLATE
4 36463 LYMPHOHAEMOPOIETIC MALIGNANCIES//QUIRRA SYNDROME//ADULT GENETIC DISEASE
5 3501 MTHFR//FOLATE//METHYLENETETRAHYDROFOLATE REDUCTASE
6 13517 NEURULATION//POSTERIOR NEUROPORE//CURLY TAIL
7 15990 MYELOMENINGOCELE//FETAL SURGERY//SPINA BIFIDA
8 2199 CLEFT PALATE//CLEFT LIP//VAN DER WOUDE SYNDROME
9 31131 BELOW SEA LEVEL//RAMAS FERTIL//HUMAN GENOME GENET DISORDERS
10 10258 THROMBOPHILIA//RECURRENT PREGNANCY LOSS//RECURRENT MISCARRIAGE

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