Class information for:
Level 1: MULTICELLULAR SPHEROIDS//MULTICELLULAR TUMOR SPHEROIDS//SPHEROID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14991 737 33.5 58%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
408 3       CHIM BIOINORGAN//POLO SCI//CARBONIC ANHYDRASE 29468
1363 2             TIRAPAZAMINE//DT DIAPHORASE//BIOREDUCTIVE DRUGS 8244
14991 1                   MULTICELLULAR SPHEROIDS//MULTICELLULAR TUMOR SPHEROIDS//SPHEROID 737

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MULTICELLULAR SPHEROIDS authKW 237776 4% 21% 27
2 MULTICELLULAR TUMOR SPHEROIDS authKW 220100 3% 25% 21
3 SPHEROID authKW 184137 9% 7% 64
4 MULTICELLULAR RESISTANCE authKW 156155 1% 54% 7
5 DU 145 PROSTATE CELL LINE authKW 82861 0% 100% 2
6 MYC RAS CO TRANSFECTION authKW 82861 0% 100% 2
7 MULTICELLULAR LAYER authKW 74573 0% 60% 3
8 MULTICELLULAR TUMOUR SPHEROIDS authKW 66284 1% 40% 4
9 RAT EMBRYO FIBROBLASTS authKW 62143 0% 50% 3
10 CONFLUENCE DEPENDENT RESISTANCE authKW 55239 0% 67% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 7529 52% 0% 384
2 CYTOLOGY & HISTOLOGY 2167 3% 0% 20
3 Radiology, Nuclear Medicine & Medical Imaging 830 14% 0% 103
4 Biology 523 8% 0% 60
5 Cell Biology 415 14% 0% 102
6 Biophysics 233 7% 0% 55
7 Mathematical & Computational Biology 38 2% 0% 12
8 Medicine, Research & Experimental 22 3% 0% 24
9 Pathology 16 2% 0% 15
10 Physiology 12 2% 0% 18

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHIM BIOL MOL EA 3306 41431 0% 100% 1
2 BIOL MOL PATOL 41431 0% 100% 1
3 BIOTECFTNTCAL PROBLEMS 41431 0% 100% 1
4 BIOTECHN PROBLEMS DIAGNOST 41431 0% 100% 1
5 CANC CELL SEPARAT IL 41431 0% 100% 1
6 DIAGNOST PROBLEMS CRYOBIOL CRIOMED 41431 0% 100% 1
7 EDUC CELL PROLIFERAT REGULAT 41431 0% 100% 1
8 ENVIRONM HLTH CARE UNIT 41431 0% 100% 1
9 IFR 51 41431 0% 100% 1
10 IFR 53 EA 2063 41431 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL AND TISSUE KINETICS 11923 2% 2% 13
2 RECENT RESULTS IN CANCER RESEARCH 7887 1% 2% 10
3 BRITISH JOURNAL OF CANCER 6461 7% 0% 53
4 RADIATION RESEARCH 4911 4% 0% 28
5 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 3242 5% 0% 37
6 CANCER DRUG DELIVERY 3209 0% 3% 3
7 EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY 2645 1% 1% 11
8 CELL PROLIFERATION 2641 1% 1% 9
9 ANTICANCER RESEARCH 2322 4% 0% 33
10 CANCER RESEARCH 1822 6% 0% 42

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MULTICELLULAR SPHEROIDS 237776 4% 21% 27 Search MULTICELLULAR+SPHEROIDS Search MULTICELLULAR+SPHEROIDS
2 MULTICELLULAR TUMOR SPHEROIDS 220100 3% 25% 21 Search MULTICELLULAR+TUMOR+SPHEROIDS Search MULTICELLULAR+TUMOR+SPHEROIDS
3 SPHEROID 184137 9% 7% 64 Search SPHEROID Search SPHEROID
4 MULTICELLULAR RESISTANCE 156155 1% 54% 7 Search MULTICELLULAR+RESISTANCE Search MULTICELLULAR+RESISTANCE
5 DU 145 PROSTATE CELL LINE 82861 0% 100% 2 Search DU+145+PROSTATE+CELL+LINE Search DU+145+PROSTATE+CELL+LINE
6 MYC RAS CO TRANSFECTION 82861 0% 100% 2 Search MYC+RAS+CO+TRANSFECTION Search MYC+RAS+CO+TRANSFECTION
7 MULTICELLULAR LAYER 74573 0% 60% 3 Search MULTICELLULAR+LAYER Search MULTICELLULAR+LAYER
8 MULTICELLULAR TUMOUR SPHEROIDS 66284 1% 40% 4 Search MULTICELLULAR+TUMOUR+SPHEROIDS Search MULTICELLULAR+TUMOUR+SPHEROIDS
9 RAT EMBRYO FIBROBLASTS 62143 0% 50% 3 Search RAT+EMBRYO+FIBROBLASTS Search RAT+EMBRYO+FIBROBLASTS
10 CONFLUENCE DEPENDENT RESISTANCE 55239 0% 67% 2 Search CONFLUENCE+DEPENDENT+RESISTANCE Search CONFLUENCE+DEPENDENT+RESISTANCE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MUELLERKLIESER, W , (1987) MULTICELLULAR SPHEROIDS - A REVIEW ON CELLULAR AGGREGATES IN CANCER-RESEARCH.JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. VOL. 113. ISSUE 2. P. 101-122 88 64% 233
2 DUBESSY, C , MERLIN, JL , MARCHAL, C , GUILLEMIN, F , (2000) SPHEROIDS IN RADIOBIOLOGY AND PHOTODYNAMIC THERAPY.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 36. ISSUE 2-3. P. 179-192 65 59% 60
3 DESOIZE, B , JARDILLIER, JC , (2000) MULTICELLULAR RESISTANCE: A PARADIGM FOR CLINICAL RESISTANCE?.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 36. ISSUE 2-3. P. 193 -207 67 43% 206
4 DESOIZE, B , GIMONET, D , JARDILLER, JC , (1998) CELL CULTURE AS SPHEROIDS: AN APPROACH TO MULTICELLULAR RESISTANCE.ANTICANCER RESEARCH. VOL. 18. ISSUE 6A. P. 4147 -4158 65 44% 65
5 SUTHERLAND, RM , (1988) CELL AND ENVIRONMENT INTERACTIONS IN TUMOR MICROREGIONS - THE MULTICELL SPHEROID MODEL.SCIENCE. VOL. 240. ISSUE 4849. P. 177-184 43 43% 1205
6 INGRAM, M , TECHY, GB , WARD, BR , IMAM, SA , ATKINSON, R , HO, H , TAYLOR, CR , (2010) TISSUE ENGINEERED TUMOR MODELS.BIOTECHNIC & HISTOCHEMISTRY. VOL. 85. ISSUE 4. P. 213-229 27 64% 15
7 ERLANSON, M , DANIELSZOLGAY, E , CARLSSON, J , (1992) RELATIONS BETWEEN THE PENETRATION, BINDING AND AVERAGE CONCENTRATION OF CYTOSTATIC DRUGS IN HUMAN TUMOR SPHEROIDS.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 29. ISSUE 5. P. 343-353 28 90% 54
8 CARLSSON, J , NEDERMAN, T , (1989) TUMOR SPHEROID TECHNOLOGY IN CANCER-THERAPY RESEARCH.EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY. VOL. 25. ISSUE 8. P. 1127-1133 38 78% 29
9 OLIVE, PL , DURAND, RE , (1994) DRUG AND RADIATION-RESISTANCE IN SPHEROIDS - CELL CONTACT AND KINETICS.CANCER AND METASTASIS REVIEWS. VOL. 13. ISSUE 2. P. 121-138 43 44% 179
10 GORLACH, A , ACKER, H , (1994) PO(2)-GRADIENTS AND PH-GRADIENTS IN MULTICELLULAR SPHEROIDS AND THEIR RELATIONSHIP TO CELLULAR-METABOLISM AND RADIATION SENSITIVITY OF MALIGNANT HUMAN TUMOR-CELLS.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. VOL. 1227. ISSUE 3. P. 105-112 34 69% 22

Classes with closest relation at Level 1


Rank Class id link
1 9229 SPHEROID//3D CELL CULTURE//TUMOR SPHEROIDS
2 4000 CELLULAR POTTS MODEL//HARVARD MIT HST ATHINOULA A MARTINOS BIOMED I//COMPLEX BIOSYST MODELING
3 18162 HUMAN MALIGNANT GLIOMAS//MOL EXPT RADIOL//GLIOMA
4 14780 PREDICTIVE ASSAY//INDIVIDUAL RADIOSENSITIVITY//RADIOSENSITIVITY
5 28175 CANC UK MRC//REPLICON INITIATION//HYPOXIA REOXYGENATION H R
6 35768 QUIESCENT CELL//BORON TRACEDRUG//MILD TEMPERATURE HYPERTHERMIA
7 30507 MESOTHELIAL CELLS//RAT MAMMARY CARCINOMA//ADHESION POLYPEPTIDES
8 10481 INTERSTITIAL FLUID PRESSURE//EDWIN L STEELE//CANCER DETECTION AND TREATMENT
9 2109 CARBOGEN//TUMOR HYPOXIA//TUMOR OXYGENATION
10 32525 DIVERSITY OF COMPLEXITY//GENE MODULATOR//KAULATH

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