Class information for:
Level 1: SODIUM CHANNEL//USE DEPENDENT BLOCK//NA CHANNEL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1563 2592 36.9 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
896 2             AMIODARONE//ANTIARRHYTHMIC DRUGS//PROPAFENONE 11339
1563 1                   SODIUM CHANNEL//USE DEPENDENT BLOCK//NA CHANNEL 2592

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SODIUM CHANNEL authKW 253387 9% 10% 223
2 USE DEPENDENT BLOCK authKW 113994 1% 44% 22
3 NA CHANNEL authKW 113613 3% 12% 78
4 JOURNAL OF GENERAL PHYSIOLOGY journal 102800 7% 5% 170
5 CARDIAC ELE OPHYSIOL S address 99522 1% 65% 13
6 BATRACHOTOXIN authKW 92416 1% 41% 19
7 FAST INACTIVATION authKW 71080 1% 46% 13
8 RO 22 9194 authKW 70673 0% 100% 6
9 SODIUM CHANNEL DENSITY authKW 49077 0% 83% 5
10 S6 SEGMENTS authKW 47115 0% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Physiology 20705 31% 0% 803
2 Biophysics 5595 18% 0% 454
3 Pharmacology & Pharmacy 1995 18% 0% 472
4 Neurosciences 1787 17% 0% 449
5 Cardiac & Cardiovascular System 1599 11% 0% 282
6 Biochemistry & Molecular Biology 1114 21% 0% 542
7 Cell Biology 551 9% 0% 244
8 Biology 340 4% 0% 102
9 Peripheral Vascular Diseases 320 4% 0% 104
10 Hematology 69 2% 0% 63

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARDIAC ELE OPHYSIOL S 99522 1% 65% 13
2 EXPTL CARDIOL HEART ELE OPHYSIOL 35336 0% 100% 3
3 ANESTHESIA S 24936 0% 35% 6
4 UNITA FARMACOL 24038 0% 29% 7
5 MED MED SECT MOL CELLULAR CARDIOL 23558 0% 100% 2
6 AUTISME PSYCHOSES EVOLUT LENTE ADULTE 11779 0% 100% 1
7 CARDIAC ELE OPHYSIOL S MC6094 11779 0% 100% 1
8 CARDIAC ELE OPHYSIOL S MC6094 MED 11779 0% 100% 1
9 CARDIOL MOL CELLULAR CARDIOL 11779 0% 100% 1
10 CARDIOL MONROE 3555 11779 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF GENERAL PHYSIOLOGY 102800 7% 5% 170
2 BIOPHYSICAL JOURNAL 25998 8% 1% 208
3 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 22226 5% 2% 125
4 JOURNAL OF MEMBRANE BIOLOGY 15321 3% 2% 78
5 EUROPEAN BIOPHYSICS JOURNAL 13026 0% 9% 12
6 JOURNAL OF PHYSIOLOGY-LONDON 8661 5% 1% 117
7 MOLECULAR PHARMACOLOGY 6867 3% 1% 76
8 GENERAL PHYSIOLOGY AND BIOPHYSICS 6617 1% 2% 31
9 NEUROPHYSIOLOGY 5135 1% 2% 29
10 CIRCULATION RESEARCH 4252 2% 1% 61

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SODIUM CHANNEL 253387 9% 10% 223 Search SODIUM+CHANNEL Search SODIUM+CHANNEL
2 USE DEPENDENT BLOCK 113994 1% 44% 22 Search USE+DEPENDENT+BLOCK Search USE+DEPENDENT+BLOCK
3 NA CHANNEL 113613 3% 12% 78 Search NA+CHANNEL Search NA+CHANNEL
4 BATRACHOTOXIN 92416 1% 41% 19 Search BATRACHOTOXIN Search BATRACHOTOXIN
5 FAST INACTIVATION 71080 1% 46% 13 Search FAST+INACTIVATION Search FAST+INACTIVATION
6 RO 22 9194 70673 0% 100% 6 Search RO+22+9194 Search RO+22+9194
7 SODIUM CHANNEL DENSITY 49077 0% 83% 5 Search SODIUM+CHANNEL+DENSITY Search SODIUM+CHANNEL+DENSITY
8 S6 SEGMENTS 47115 0% 100% 4 Search S6+SEGMENTS Search S6+SEGMENTS
9 SINGLE CARDIAC NA CHANNELS 47115 0% 100% 4 Search SINGLE+CARDIAC+NA+CHANNELS Search SINGLE+CARDIAC+NA+CHANNELS
10 SODIUM CURRENT 39777 1% 10% 33 Search SODIUM+CURRENT Search SODIUM+CURRENT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ULBRICHT, W , (2005) SODIUM CHANNEL INACTIVATION: MOLECULAR DETERMINANTS AND MODULATION.PHYSIOLOGICAL REVIEWS. VOL. 85. ISSUE 4. P. 1271-1301 234 52% 143
2 FOZZARD, HA , HANCK, DA , (1996) STRUCTURE AND FUNCTION OF VOLTAGE-DEPENDENT SODIUM CHANNELS: COMPARISON OF BRAIN II AND CARDIAC ISOFORMS.PHYSIOLOGICAL REVIEWS. VOL. 76. ISSUE 3. P. 887-926 154 69% 184
3 CATTERALL, WA , (1992) CELLULAR AND MOLECULAR-BIOLOGY OF VOLTAGE-GATED SODIUM-CHANNELS.PHYSIOLOGICAL REVIEWS. VOL. 72. ISSUE 4. P. S15-S48 138 64% 376
4 GAWALI, VS , TODT, H , (2016) MECHANISM OF INACTIVATION IN VOLTAGE-GATED NA+ CHANNELS.NA CHANNELS FROM PHYLA TO FUNCTION. VOL. 78. ISSUE . P. 409 -450 98 51% 1
5 NEUMCKE, B , (1990) DIVERSITY OF SODIUM-CHANNELS IN ADULT AND CULTURED-CELLS, IN OOCYTES AND IN LIPID BILAYERS.REVIEWS OF PHYSIOLOGY BIOCHEMISTRY AND PHARMACOLOGY. VOL. 115. ISSUE . P. 1-49 129 88% 21
6 AHERN, CA , PAYANDEH, J , BOSMANS, F , CHANDA, B , (2016) THE HITCHHIKER'S GUIDE TO THE VOLTAGE-GATED SODIUM CHANNEL GALAXY.JOURNAL OF GENERAL PHYSIOLOGY. VOL. 147. ISSUE 1. P. 1 -24 85 34% 9
7 HUANG, CJ , SCHILD, L , MOCZYDLOWSKI, EG , (2012) USE-DEPENDENT BLOCK OF THE VOLTAGE-GATED NA+ CHANNEL BY TETRODOTOXIN AND SAXITOXIN: EFFECT OF PORE MUTATIONS THAT CHANGE IONIC SELECTIVITY.JOURNAL OF GENERAL PHYSIOLOGY. VOL. 140. ISSUE 4. P. 435 -454 60 75% 10
8 BARCHI, RL , (1988) PROBING THE MOLECULAR-STRUCTURE OF THE VOLTAGE-DEPENDENT SODIUM-CHANNEL.ANNUAL REVIEW OF NEUROSCIENCE. VOL. 11. ISSUE . P. 455-495 104 85% 117
9 FOZZARD, HA , LEE, PJ , LIPKIND, GM , (2005) MECHANISM OF LOCAL ANESTHETIC DRUG ACTION ON VOLTAGE-GATED SODIUM CHANNELS.CURRENT PHARMACEUTICAL DESIGN. VOL. 11. ISSUE 21. P. 2671-2686 60 80% 91
10 CERVENKA, R , ZARRABI, T , LUKACS, P , TODT, H , (2010) THE OUTER VESTIBULE OF THE NA+ CHANNEL-TOXIN RECEPTOR AND MODULATOR OF PERMEATION AS WELL AS GATING.MARINE DRUGS. VOL. 8. ISSUE 4. P. 1373-1393 69 68% 4

Classes with closest relation at Level 1


Rank Class id link
1 34620 BDF 9148//DPI 201 106//NA CHANNEL ACTIVATOR
2 3671 NEUROSCI REGENERAT//SODIUM CHANNEL//NAV17
3 2318 KCSA//JOURNAL OF GENERAL PHYSIOLOGY//MOL NEUROBIOL BIOPHYS
4 35963 CUTANEOUS ANALGESIA//INFILTRATIVE CUTANEOUS ANALGESIA//SPINAL BLOCKADE
5 18324 TIME INTERVAL OMISSION//MARKOV REPAIRABLE SYSTEM//ION CHANNEL MODELING
6 8146 PERIODIC PARALYSIS//MYOTONIA CONGENITA//HYPOKALEMIC PERIODIC PARALYSIS
7 23312 MUSCLE CELL LINE//LARGE CONDUCTANCE CHANNEL//COUNTER ION CHANNEL
8 36861 FISIOL CELLUARE//INDENOLOL//K COMPETITION
9 18583 RANOLAZINE//LATE SODIUM CURRENT//LATE I NA
10 3795 PROPAFENONE//FLECAINIDE//MEXILETINE

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