Class information for:
Level 2: AMIODARONE//ANTIARRHYTHMIC DRUGS//PROPAFENONE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
896 11339 29.8 58%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
896 2             AMIODARONE//ANTIARRHYTHMIC DRUGS//PROPAFENONE 11339
1563 1                   SODIUM CHANNEL//USE DEPENDENT BLOCK//NA CHANNEL 2592
3795 1                   PROPAFENONE//FLECAINIDE//MEXILETINE 1906
3840 1                   CARDIAC & CARDIOVASCULAR SYSTEM//PROGRAMMED VENTRICULAR STIMULATION//ELECTROPHYSIOLOGICAL TESTING 1897
3886 1                   AMIODARONE//DESETHYLAMIODARONE//INTRAVENOUS AMIODARONE 1887
7162 1                   SOTALOL//DOFETILIDE//CLASS III ANTIARRHYTHMIC AGENT 1398
15499 1                   CIBENZOLINE//DISOPYRAMIDE//AH 1058 709
26415 1                   PRIMARY VENTRICULAR FIBRILLATION//ACSIS REGISTRY//ACUTE LIPEMIA 255
27140 1                   MORICIZINE//ETHMOZINE//TIRACIZINE 236
27637 1                   N ACETYLPROCAINAMIDE//ABUNDANCE OF ECTOPARASITES//ANTIARRHYTHMIC PROCANBIDR 224
30780 1                   1 AZABICYCLO330OCTANE//PILSICAINIDE HYDROCHLORIDE//SUN 1165 163
36861 1                   FISIOL CELLUARE//INDENOLOL//K COMPETITION 72

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 AMIODARONE authKW 482442 4% 37% 484
2 ANTIARRHYTHMIC DRUGS authKW 121137 2% 21% 210
3 PROPAFENONE authKW 117871 1% 41% 108
4 SOTALOL authKW 111496 1% 39% 107
5 CARDIAC & CARDIOVASCULAR SYSTEM WoSSC 109889 39% 1% 4405
6 FLECAINIDE authKW 109636 1% 36% 113
7 DESETHYLAMIODARONE authKW 74466 0% 86% 32
8 DOFETILIDE authKW 70130 1% 41% 64
9 ANTIARRHYTHMIC authKW 66466 1% 26% 94
10 SODIUM CHANNEL authKW 63968 2% 10% 235

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cardiac & Cardiovascular System 109889 39% 1% 4405
2 Pharmacology & Pharmacy 22613 27% 0% 3116
3 Peripheral Vascular Diseases 4755 7% 0% 760
4 Physiology 4737 8% 0% 901
5 Medicine, General & Internal 1856 8% 0% 857
6 Biophysics 877 4% 0% 489
7 Engineering, Biomedical 558 2% 0% 265
8 Chemistry, Medicinal 537 3% 0% 321
9 Toxicology 500 3% 0% 317
10 Critical Care Medicine 182 1% 0% 130

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARDIAC ELE OPHYSIOL S 22730 0% 65% 13
2 CARDIOVASC THER Y UNIT 12106 0% 75% 6
3 MED CARDIOL SECT 8406 0% 26% 12
4 EXPTL CARDIOL HEART ELE OPHYSIOL 8073 0% 100% 3
5 H 10 8073 0% 100% 3
6 ANESTHESIA S 5691 0% 35% 6
7 UNITA FARMACOL 5484 0% 29% 7
8 ANESTHESIOL EXPT PHYSIOL CELLULAIRE E3212 5382 0% 100% 2
9 CLIN NEW DRUGS THER EUT 5382 0% 100% 2
10 DIPARTIMENTO MED INTERNA SEZ CARDIOL 5382 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMERICAN JOURNAL OF CARDIOLOGY 56532 7% 3% 752
2 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 45358 4% 4% 433
3 AMERICAN HEART JOURNAL 39948 4% 3% 464
4 JOURNAL OF GENERAL PHYSIOLOGY 23792 2% 5% 172
5 PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY 16951 2% 3% 238
6 EUROPEAN HEART JOURNAL 15255 2% 2% 242
7 JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 12599 2% 2% 275
8 ZEITSCHRIFT FUR KARDIOLOGIE 12474 1% 3% 138
9 KARDIOLOGIYA 11771 2% 3% 171
10 ARCHIVES DES MALADIES DU COEUR ET DES VAISSEAUX 9337 1% 2% 150

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AMIODARONE 482442 4% 37% 484 Search AMIODARONE Search AMIODARONE
2 ANTIARRHYTHMIC DRUGS 121137 2% 21% 210 Search ANTIARRHYTHMIC+DRUGS Search ANTIARRHYTHMIC+DRUGS
3 PROPAFENONE 117871 1% 41% 108 Search PROPAFENONE Search PROPAFENONE
4 SOTALOL 111496 1% 39% 107 Search SOTALOL Search SOTALOL
5 FLECAINIDE 109636 1% 36% 113 Search FLECAINIDE Search FLECAINIDE
6 DESETHYLAMIODARONE 74466 0% 86% 32 Search DESETHYLAMIODARONE Search DESETHYLAMIODARONE
7 DOFETILIDE 70130 1% 41% 64 Search DOFETILIDE Search DOFETILIDE
8 ANTIARRHYTHMIC 66466 1% 26% 94 Search ANTIARRHYTHMIC Search ANTIARRHYTHMIC
9 SODIUM CHANNEL 63968 2% 10% 235 Search SODIUM+CHANNEL Search SODIUM+CHANNEL
10 MEXILETINE 63079 1% 31% 76 Search MEXILETINE Search MEXILETINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ULBRICHT, W , (2005) SODIUM CHANNEL INACTIVATION: MOLECULAR DETERMINANTS AND MODULATION.PHYSIOLOGICAL REVIEWS. VOL. 85. ISSUE 4. P. 1271-1301 234 52% 143
2 GILL, J , HEEL, RC , FITTON, A , (1992) AMIODARONE - AN OVERVIEW OF ITS PHARMACOLOGICAL PROPERTIES, AND REVIEW OF ITS THERAPEUTIC USE IN CARDIAC-ARRHYTHMIAS.DRUGS. VOL. 43. ISSUE 1. P. 69 -110 206 78% 135
3 FOZZARD, HA , HANCK, DA , (1996) STRUCTURE AND FUNCTION OF VOLTAGE-DEPENDENT SODIUM CHANNELS: COMPARISON OF BRAIN II AND CARDIAC ISOFORMS.PHYSIOLOGICAL REVIEWS. VOL. 76. ISSUE 3. P. 887-926 154 69% 184
4 MASON, JW , (1987) DRUG-THERAPY - AMIODARONE.NEW ENGLAND JOURNAL OF MEDICINE. VOL. 316. ISSUE 8. P. 455-466 131 89% 434
5 BRYSON, HM , PALMER, KJ , LANGTRY, HD , FITTON, A , (1993) PROPAFENONE - A REAPPRAISAL OF ITS PHARMACOLOGY, PHARMACOKINETICS AND THERAPEUTIC USE IN CARDIAC-ARRHYTHMIAS.DRUGS. VOL. 45. ISSUE 1. P. 85 -130 158 80% 59
6 CATTERALL, WA , (1992) CELLULAR AND MOLECULAR-BIOLOGY OF VOLTAGE-GATED SODIUM-CHANNELS.PHYSIOLOGICAL REVIEWS. VOL. 72. ISSUE 4. P. S15-S48 138 64% 376
7 TRIANTAFILLIDOU, C , KOLILEKAS, L , MARKOULAKI, D , MANALI, ED , PAPIRIS, SA , (2010) AMIODARONE REVIEW OF PULMONARY EFFECTS AND TOXICITY.DRUG SAFETY. VOL. 33. ISSUE 7. P. 539 -558 89 72% 49
8 FITTON, A , SORKIN, EM , (1993) SOTALOL - AN UPDATED REVIEW OF ITS PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC USE IN CARDIAC-ARRHYTHMIAS.DRUGS. VOL. 46. ISSUE 4. P. 678 -719 150 75% 42
9 KODAMA, I , KAMIYA, K , TOYAMA, J , (1997) CELLULAR ELECTROPHARMACOLOGY OF AMIODARONE.CARDIOVASCULAR RESEARCH. VOL. 35. ISSUE 1. P. 13 -29 114 70% 178
10 NESTICO, PF , MORGANROTH, J , HOROWITZ, LN , (1988) NEW ANTIARRHYTHMIC DRUGS.DRUGS. VOL. 35. ISSUE 3. P. 286-319 146 99% 19

Classes with closest relation at Level 2


Rank Class id link
1 1064 LONG QT SYNDROME//BRUGADA SYNDROME//QT INTERVAL
2 853 CATHETER ABLATION//VENTRICULAR TACHYCARDIA//ATRIAL FLUTTER
3 656 PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY//IMPLANTABLE CARDIOVERTER DEFIBRILLATOR//PACEMAKER
4 691 POTASSIUM CHANNELS//BK CHANNEL//RETIGABINE
5 3016 MITRAL VALVE PROLAPSE//TOYOOKA JR//HUMAN RIB BONE
6 2131 SCORPION TOXIN//SCORPION VENOM//CONOTOXIN
7 2637 IVABRADINE//SINOATRIAL NODE//HCN CHANNELS
8 377 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY//PHOSPHOLAMBAN//CARDIAC & CARDIOVASCULAR SYSTEM
9 1489 SPIRAL WAVE//T WAVE ALTERNANS//OPTICAL MAPPING
10 3086 NODE OF RANVIER//NERVE EXCITABILITY//AXON INITIAL SEGMENT

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