Class information for:
Level 1: 1 AZABICYCLO330OCTANE//PILSICAINIDE HYDROCHLORIDE//SUN 1165

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
30780 163 20.0 49%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
896 2             AMIODARONE//ANTIARRHYTHMIC DRUGS//PROPAFENONE 11339
30780 1                   1 AZABICYCLO330OCTANE//PILSICAINIDE HYDROCHLORIDE//SUN 1165 163

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 1 AZABICYCLO330OCTANE authKW 780558 3% 83% 5
2 PILSICAINIDE HYDROCHLORIDE authKW 562003 2% 100% 3
3 SUN 1165 authKW 562003 2% 100% 3
4 PILSICAINIDE authKW 539941 9% 21% 14
5 PERHYDROPYRROLIZINE authKW 374669 1% 100% 2
6 SK 946 authKW 280999 2% 50% 3
7 1H 3H THIAZOLO3 4 ABENZIMIDAZOLES authKW 249778 1% 67% 2
8 1 7 DIIODO 4 HEPTANONE authKW 187334 1% 100% 1
9 1 AZABICYCLO331NONANE authKW 187334 1% 100% 1
10 1 AZABICYCLO421NONANE authKW 187334 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 576 36% 0% 58
2 Chemistry, Medicinal 519 17% 0% 28
3 Chemistry, Organic 314 21% 0% 34
4 Cardiac & Cardiovascular System 132 12% 0% 20
5 Gastroenterology & Hepatology 64 7% 0% 11
6 Crystallography 41 5% 0% 8
7 Chemistry, Multidisciplinary 12 9% 0% 14
8 Virology 5 2% 0% 3
9 Chemistry, Inorganic & Nuclear 2 2% 0% 4
10 Peripheral Vascular Diseases 2 2% 0% 3

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEV HIGASHI KU 187334 1% 100% 1
2 HONJO CLIN 2 187334 1% 100% 1
3 MED HLTH SCI PHYSIOL PHARMACOL 187334 1% 100% 1
4 EVALUAT ANAL DRUG INFORMAT 12487 1% 7% 1
5 WOLTERS KLUWER BUSINESS 5675 1% 3% 1
6 DIPARTIMENTO CHIM INORGAN CHIM ANALIT CHIM FIS 5626 2% 1% 4
7 DIPARTIMENTO FARMACOCHIM 4678 3% 1% 5
8 IST CHIM FARMACEUT TOSSICOL PIETRO PRATESI 4161 1% 2% 1
9 AFFILIATED BEIJING ANZHEN HOSP 4071 1% 2% 1
10 HYGIEN CHEM 3821 1% 2% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FARMACO 5237 4% 0% 7
2 ANTIVIRAL CHEMISTRY & CHEMOTHERAPY 3400 2% 1% 3
3 JAPANESE HEART JOURNAL 2205 3% 0% 5
4 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 1527 4% 0% 6
5 HETEROCYCLES 1413 6% 0% 10
6 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 1055 3% 0% 5
7 MANUFACTURING CHEMIST 1011 1% 1% 1
8 CARDIOSCIENCE 912 1% 0% 1
9 RESEARCH COMMUNICATIONS IN PSYCHOLOGY PSYCHIATRY AND BEHAVIOR 716 1% 0% 1
10 PHARMACEUTICAL CHEMISTRY JOURNAL 672 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 1 AZABICYCLO330OCTANE 780558 3% 83% 5 Search 1+AZABICYCLO330OCTANE Search 1+AZABICYCLO330OCTANE
2 PILSICAINIDE HYDROCHLORIDE 562003 2% 100% 3 Search PILSICAINIDE+HYDROCHLORIDE Search PILSICAINIDE+HYDROCHLORIDE
3 SUN 1165 562003 2% 100% 3 Search SUN+1165 Search SUN+1165
4 PILSICAINIDE 539941 9% 21% 14 Search PILSICAINIDE Search PILSICAINIDE
5 PERHYDROPYRROLIZINE 374669 1% 100% 2 Search PERHYDROPYRROLIZINE Search PERHYDROPYRROLIZINE
6 SK 946 280999 2% 50% 3 Search SK+946 Search SK+946
7 1H 3H THIAZOLO3 4 ABENZIMIDAZOLES 249778 1% 67% 2 Search 1H+3H+THIAZOLO3+4+ABENZIMIDAZOLES Search 1H+3H+THIAZOLO3+4+ABENZIMIDAZOLES
8 1 7 DIIODO 4 HEPTANONE 187334 1% 100% 1 Search 1+7+DIIODO+4+HEPTANONE Search 1+7+DIIODO+4+HEPTANONE
9 1 AZABICYCLO331NONANE 187334 1% 100% 1 Search 1+AZABICYCLO331NONANE Search 1+AZABICYCLO331NONANE
10 1 AZABICYCLO421NONANE 187334 1% 100% 1 Search 1+AZABICYCLO421NONANE Search 1+AZABICYCLO421NONANE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CHIMIRRI, A , MONFORTE, AM , MONFORTE, P , NICOLO, F , RAO, A , ZAPPALA, M , (2000) SYNTHESIS AND STRUCTURAL FEATURES OF NEW CYCLOFUNCTIONALIZED BENZIMIDAZOLES.HETEROCYCLES. VOL. 53. ISSUE 3. P. 613-+ 11 79% 5
2 HASHIMOTO, H , NAKASHIMA, M , (1993) PILSICAINIDE, A NEW CLASS-I ANTIARRHYTHMIC DRUG.CARDIOVASCULAR DRUG REVIEWS. VOL. 11. ISSUE 1. P. 60-73 12 92% 3
3 OE, K , NAGATA, M , MORI, K , (2009) PILSICAINIDE INTOXICATION PRESENTING AS LEFT VENTRICULAR DYSSYNCHRONY IN A PATIENT ON HEMODIALYSIS.JOURNAL OF CARDIOLOGY. VOL. 53. ISSUE 1. P. 136-139 8 80% 0
4 QIU, Q , LIU, WF , LI, J , WEI, YX , YANG, KX , SUO, W , WU, W , DU, HY , ZHANG, YC , ZHAO, GP , ET AL (2014) PHARMACOKINETICS OF PILSICAINIDE HYDROCHLORIDE FOR INJECTION IN HEALTHY CHINESE VOLUNTEERS: A RANDOMIZED, PARALLEL-GROUP, OPEN-LABEL, SINGLE-DOSE STUDY.CLINICAL THERAPEUTICS. VOL. 36. ISSUE 2. P. 255-263 9 60% 1
5 INO, T , ATARASHI, H , KURUMA, A , ONODERA, T , SAITOH, H , HAYAKAWA, H , (1998) ELECTROPHYSIOLOGIC AND HEMODYNAMIC EFFECTS OF A SINGLE ORAL DOSE OF PILSICAINIDE HYDROCHLORIDE, A NEW CLASS 1C ANTIARRHYTHMIC AGENT.JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. VOL. 31. ISSUE 1. P. 157 -164 14 52% 12
6 OKA, M , BABA, K , NAKAMURA, K , DONG, LL , HAMAJIMA, H , UNNO, R , MATSUMOTO, Y , (2003) SYNTHESIS OF 1-AZABICYCLIC SYSTEMS BY DOUBLE CYCLIZATION.JOURNAL OF HETEROCYCLIC CHEMISTRY. VOL. 40. ISSUE 1. P. 177 -180 7 78% 6
7 PLOSKER, GL , (2010) PILSICAINIDE.DRUGS. VOL. 70. ISSUE 4. P. 455 -467 12 34% 1
8 NICOLO, F , BRUNO, G , SCOPELLITI, R , GRASSO, S , RAO, A , ZAPPALA, M , (2001) 7-CHLORO-1-(2,6-DIFLUOROPHENYL)-1H,3H-THIAZOLO[3,4-A]BENZIMIDAZOLE AND 1-(2,6-DIFLUOROPHENYL)-6-METHYL-1H,3H-THIAZOLO[3,4-A]BENZIMIDAZOLE.ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY. VOL. 57. ISSUE . P. 572 -574 5 100% 5
9 BRUNO, C , CATALANO, A , LENTINI, G , CAROCCI, A , FRANCHINI, C , TORTORELLA, V , (2008) FACILE ENTRY TO ETHYL TETRAHYDRO-1H-PYRROLIZIN-7A(5H)-YLACETATE: A VERSATILE PHARMACEUTICAL INTERMEDIATE.HETEROCYCLES. VOL. 75. ISSUE 9. P. 2193 -2200 8 50% 7
10 SPARATORE, A , BASILICO, N , CASAGRANDE, M , PARAPINI, S , TARAMELLI, D , BRUN, R , WITTLIN, S , SPARATORE, F , (2008) ANTIMALARIAL ACTIVITY OF NOVEL PYRROLIZIDINYL DERIVATIVES OF 4-AMINOQUINOLINE.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 18. ISSUE 13. P. 3737 -3740 7 54% 23

Classes with closest relation at Level 1


Rank Class id link
1 33697 1 AZATRICYCLOHEPTANES//2 AZABICYCLOHEPTANES//METHANOPYRROLIDINE
2 35899 4 METHYL 1 THIOXO 1 2 4 5 TETRAHYDRO1 2 4TRIAZOLO4 3 AQUINAZOLIN 5 ONE//CYCLIC THIOAMIDES//DCC AND AZIDE COUPLING
3 15499 CIBENZOLINE//DISOPYRAMIDE//AH 1058
4 30350 LICOFELONE//TEPOXALIN//2 2 DIMETHYL 6 4 CHLOROPHENYL 7 PHENYL 2 3 DIHYDRO 1H PYRROLIZINE 5 YL ACETIC ACID
5 31226 BENZODISOXAZOLES//2 3 6 11 TETRAHYDROANTHRA2 1 DISOTHIAZOLE 3 6 11 TRIONES//2 4 6 TRINITROBENZALDEHYDE
6 23922 CYCLOPROPYLIMINIUM REARRANGEMENT//5 EPITASHIROMINE//BROMOHYDRIN DIOL
7 36574 HYPERSPLENIA//NOVEL ASSAY SYSTEM//MUCOSAL ENZYMES
8 3795 PROPAFENONE//FLECAINIDE//MEXILETINE
9 36861 FISIOL CELLUARE//INDENOLOL//K COMPETITION
10 1563 SODIUM CHANNEL//USE DEPENDENT BLOCK//NA CHANNEL

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