Class information for:
Level 1: PROGRANULIN//PGRN//GRANULIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
17353 604 43.9 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
49 3       ALZHEIMERS DISEASE//AMYOTROPHIC LATERAL SCLEROSIS//DEMENTIA 92146
699 2             AMYOTROPHIC LATERAL SCLEROSIS//FRONTOTEMPORAL DEMENTIA//ALS 13006
17353 1                   PROGRANULIN//PGRN//GRANULIN 604

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROGRANULIN authKW 8249383 37% 72% 226
2 PGRN authKW 1100941 5% 78% 28
3 GRANULIN authKW 995500 5% 62% 32
4 PROGRANULIN GRN authKW 505540 2% 100% 10
5 FRONTOTEMPORAL LOBAR DEGENERATION authKW 386902 11% 11% 68
6 GRN authKW 314630 3% 33% 19
7 ACROGRANIN authKW 309642 1% 88% 7
8 GRANULIN EPITHELIN PRECURSOR authKW 309642 1% 88% 7
9 ATSTTRIN authKW 303324 1% 100% 6
10 EPITHELIN authKW 303324 1% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 2220 36% 0% 218
2 Clinical Neurology 1327 21% 0% 129
3 Geriatrics & Gerontology 606 6% 0% 34
4 Cell Biology 270 13% 0% 76
5 Biochemistry & Molecular Biology 205 19% 0% 116
6 Pathology 175 5% 0% 33
7 Genetics & Heredity 144 8% 0% 47
8 Oncology 135 10% 0% 59
9 Immunology 47 6% 0% 37
10 Medicine, Research & Experimental 46 4% 0% 27

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROBIOGEN MEMORY CLIN 169902 2% 31% 11
2 NEURODEGENERAT BRAIN DIS GRP 164520 4% 13% 25
3 ROBERT H CLARICE SMITH ABIGAIL BUREN ALZHEIME 151662 0% 100% 3
4 TREATMENT COGNIT DYSFUNCT 136618 2% 27% 10
5 NEUROBIOGEN 132080 1% 29% 9
6 PROGRAM ONCOL 120924 3% 15% 16
7 MOL GENET NEUROSCI NEUROL NEUROTHER EUT 101108 0% 100% 2
8 NEUROL SC 3 101108 0% 100% 2
9 JOSE CARRERAS IMMUNO GENE THER Y INTERNA 90995 0% 60% 3
10 BIOL PROSTATE CANC PROGRAM 80882 1% 40% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF ALZHEIMERS DISEASE 16122 6% 1% 38
2 NEUROBIOLOGY OF AGING 5035 4% 0% 24
3 NEURODEGENERATIVE DISEASES 2633 1% 1% 6
4 JOURNAL OF REPRODUCTION AND DEVELOPMENT 2276 1% 1% 8
5 MOLECULAR NEURODEGENERATION 1442 1% 1% 4
6 BRAIN 1334 2% 0% 13
7 NEUROGENETICS 1331 1% 1% 4
8 ALZHEIMER DISEASE & ASSOCIATED DISORDERS 1288 1% 0% 6
9 EUROPEAN JOURNAL OF NEUROLOGY 1045 1% 0% 9
10 JOURNAL OF MOLECULAR NEUROSCIENCE 901 1% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PROGRANULIN 8249383 37% 72% 226 Search PROGRANULIN Search PROGRANULIN
2 PGRN 1100941 5% 78% 28 Search PGRN Search PGRN
3 GRANULIN 995500 5% 62% 32 Search GRANULIN Search GRANULIN
4 PROGRANULIN GRN 505540 2% 100% 10 Search PROGRANULIN+GRN Search PROGRANULIN+GRN
5 FRONTOTEMPORAL LOBAR DEGENERATION 386902 11% 11% 68 Search FRONTOTEMPORAL+LOBAR+DEGENERATION Search FRONTOTEMPORAL+LOBAR+DEGENERATION
6 GRN 314630 3% 33% 19 Search GRN Search GRN
7 ACROGRANIN 309642 1% 88% 7 Search ACROGRANIN Search ACROGRANIN
8 GRANULIN EPITHELIN PRECURSOR 309642 1% 88% 7 Search GRANULIN+EPITHELIN+PRECURSOR Search GRANULIN+EPITHELIN+PRECURSOR
9 ATSTTRIN 303324 1% 100% 6 Search ATSTTRIN Search ATSTTRIN
10 EPITHELIN 303324 1% 100% 6 Search EPITHELIN Search EPITHELIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KLEINBERGER, G , CAPELL, A , HAASS, C , VAN BROECKHOVEN, C , (2013) MECHANISMS OF GRANULIN DEFICIENCY: LESSONS FROM CELLULAR AND ANIMAL MODELS.MOLECULAR NEUROBIOLOGY. VOL. 47. ISSUE 1. P. 337-360 120 62% 8
2 TOH, H , CHITRAMUTHU, BP , BENNETT, HPJ , BATEMAN, A , (2011) STRUCTURE, FUNCTION, AND MECHANISM OF PROGRANULIN; THE BRAIN AND BEYOND.JOURNAL OF MOLECULAR NEUROSCIENCE. VOL. 45. ISSUE 3. P. 538-548 83 75% 39
3 DE MUYNCK, L , VAN DAMME, P , (2011) CELLULAR EFFECTS OF PROGRANULIN IN HEALTH AND DISEASE.JOURNAL OF MOLECULAR NEUROSCIENCE. VOL. 45. ISSUE 3. P. 549-560 82 78% 27
4 CENIK, B , SEPHTON, CF , CENIK, BK , HERZ, J , YU, G , (2012) PROGRANULIN: A PROTEOLYTICALLY PROCESSED PROTEIN AT THE CROSSROADS OF INFLAMMATION AND NEURODEGENERATION.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 39. P. 32298 -32306 71 75% 45
5 PETKAU, TL , LEAVITT, BR , (2014) PROGRANULIN IN NEURODEGENERATIVE DISEASE.TRENDS IN NEUROSCIENCES. VOL. 37. ISSUE 7. P. 388 -398 71 66% 19
6 BATEMAN, A , BENNETT, HPJ , (2009) THE GRANULIN GENE FAMILY: FROM CANCER TO DEMENTIA.BIOESSAYS. VOL. 31. ISSUE 11. P. 1245-1254 65 70% 135
7 GHIDONI, R , PATERLINI, A , ALBERTINI, V , BINETTI, G , BENUSSI, L , (2012) LOSING PROTEIN IN THE BRAIN: THE CASE OF PROGRANULIN.BRAIN RESEARCH. VOL. 1476. ISSUE . P. 172-182 72 73% 5
8 GASS, J , PRUDENCIO, M , STETLER, C , PETRUCELLI, L , (2012) PROGRANULIN: AN EMERGING TARGET FOR FTLD THERAPIES.BRAIN RESEARCH. VOL. 1462. ISSUE . P. 118 -128 64 71% 10
9 JIAN, JL , KONOPKA, J , LIU, CJ , (2013) INSIGHTS INTO THE ROLE OF PROGRANULIN IN IMMUNITY, INFECTION, AND INFLAMMATION.JOURNAL OF LEUKOCYTE BIOLOGY. VOL. 93. ISSUE 2. P. 199-208 60 62% 43
10 NGUYEN, AD , NGUYEN, TA , MARTEN, LH , MITIC, LL , FARESE, RV , (2013) PROGRANULIN: AT THE INTERFACE OF NEURODEGENERATIVE AND METABOLIC DISEASES.TRENDS IN ENDOCRINOLOGY AND METABOLISM. VOL. 24. ISSUE 12. P. 597-606 60 68% 16

Classes with closest relation at Level 1


Rank Class id link
1 3819 TDP 43//C9ORF72//FUS
2 2623 FRONTOTEMPORAL DEMENTIA//PRIMARY PROGRESSIVE APHASIA//SEMANTIC DEMENTIA
3 5543 PROGRESSIVE SUPRANUCLEAR PALSY//CORTICOBASAL DEGENERATION//ARGYROPHILIC GRAIN DISEASE
4 361 TAU//TAUOPATHY//PAIRED HELICAL FILAMENTS
5 11336 SORL1//TOMM40//PICALM
6 22230 DCR3//DECOY RECEPTOR 3//TL1A
7 20535 PSEUDOACHONDROPLASIA//MULTIPLE EPIPHYSEAL DYSPLASIA//MATRILIN
8 16420 PEDIAT CHILDREN SURG//SOMATIC GENOME VARIATIONS//CELL CYCLE RE ENTRY
9 7068 AMYOTROPHIC LATERAL SCLEROSIS//PRIMARY LATERAL SCLEROSIS//MOTOR NEURON DISEASE
10 14204 AGGRECANASE//ADAMTS//ADAMTS 4

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