Class information for:
Level 1: PYRIDOXINE DEPENDENT EPILEPSY//PYRIDOXINE DEPENDENT SEIZURES//ALDH7A1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
20804 445 25.7 59%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
631 3       KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE 12928
1475 2             THIAMINE//THIAMINE DEFICIENCY//WERNICKES ENCEPHALOPATHY 7673
20804 1                   PYRIDOXINE DEPENDENT EPILEPSY//PYRIDOXINE DEPENDENT SEIZURES//ALDH7A1 445

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PYRIDOXINE DEPENDENT EPILEPSY authKW 1520145 5% 92% 24
2 PYRIDOXINE DEPENDENT SEIZURES authKW 1111605 4% 90% 18
3 ALDH7A1 authKW 707840 3% 74% 14
4 ANTIQUITIN authKW 694740 4% 56% 18
5 METABOLIC EPILEPSY authKW 548943 2% 100% 8
6 PYRIDOXINE authKW 518640 14% 12% 63
7 ALDH7A1 GENE authKW 480325 2% 100% 7
8 EDUC PHARM address 231124 2% 42% 8
9 ISONIAZID INTOXICATION authKW 205854 1% 100% 3
10 PYRIDOXINE DEPENDENCY authKW 205854 1% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pediatrics 2653 27% 0% 120
2 Clinical Neurology 1887 29% 0% 129
3 Emergency Medicine 330 4% 0% 17
4 Medicine, Research & Experimental 213 9% 0% 41
5 Genetics & Heredity 152 9% 0% 40
6 Neurosciences 131 12% 0% 55
7 Endocrinology & Metabolism 100 7% 0% 31
8 Medicine, General & Internal 81 8% 0% 35
9 Toxicology 69 4% 0% 20
10 Pharmacology & Pharmacy 45 9% 0% 38

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EDUC PHARM 231124 2% 42% 8
2 ARMENIAN REPUBLICAN EPILEPSY EREBOUNI 91489 0% 67% 2
3 BANGKOK HOSP 68618 0% 100% 1
4 BIOCHEM DIS CYST FIBROSIS 68618 0% 100% 1
5 BIOCHEM DIS TREATABLE INTELLECTUAL DISABIL 68618 0% 100% 1
6 BIOMED NETWORK RARE DIS CIBERER HLTH 68618 0% 100% 1
7 CHILD NEUROL DEV REHABIL 68618 0% 100% 1
8 CHU ROUENIRIB NEOVASCERI28 68618 0% 100% 1
9 CLIN NEUROL PEDIAT 68618 0% 100% 1
10 CLIN PEDIAT KIDNEY LIVER METAB DISORDERS 68618 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF INHERITED METABOLIC DISEASE 3861 4% 0% 16
2 MOLECULAR GENETICS AND METABOLISM 3699 3% 0% 13
3 JOURNAL OF CHILD NEUROLOGY 3167 3% 0% 15
4 DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY 2832 3% 0% 14
5 PEDIATRIC NEUROLOGY 2724 3% 0% 13
6 JOURNAL OF ORTHOMOLECULAR PSYCHIATRY 2342 0% 2% 2
7 EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY 2230 1% 1% 6
8 NEUROPEDIATRICS 1207 1% 0% 6
9 BIOMEDICINE 1105 0% 2% 1
10 EPILEPTIC DISORDERS 1082 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PYRIDOXINE DEPENDENT EPILEPSY 1520145 5% 92% 24 Search PYRIDOXINE+DEPENDENT+EPILEPSY Search PYRIDOXINE+DEPENDENT+EPILEPSY
2 PYRIDOXINE DEPENDENT SEIZURES 1111605 4% 90% 18 Search PYRIDOXINE+DEPENDENT+SEIZURES Search PYRIDOXINE+DEPENDENT+SEIZURES
3 ALDH7A1 707840 3% 74% 14 Search ALDH7A1 Search ALDH7A1
4 ANTIQUITIN 694740 4% 56% 18 Search ANTIQUITIN Search ANTIQUITIN
5 METABOLIC EPILEPSY 548943 2% 100% 8 Search METABOLIC+EPILEPSY Search METABOLIC+EPILEPSY
6 PYRIDOXINE 518640 14% 12% 63 Search PYRIDOXINE Search PYRIDOXINE
7 ALDH7A1 GENE 480325 2% 100% 7 Search ALDH7A1+GENE Search ALDH7A1+GENE
8 ISONIAZID INTOXICATION 205854 1% 100% 3 Search ISONIAZID+INTOXICATION Search ISONIAZID+INTOXICATION
9 PYRIDOXINE DEPENDENCY 205854 1% 100% 3 Search PYRIDOXINE+DEPENDENCY Search PYRIDOXINE+DEPENDENCY
10 ALPHA AMINOADIPIC SEMIALDEHYDE 160099 2% 33% 7 Search ALPHA+AMINOADIPIC+SEMIALDEHYDE Search ALPHA+AMINOADIPIC+SEMIALDEHYDE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 VAN KARNEBEEK, CDM , TIEBOUT, SA , NIERMEIJER, J , POLL-THE, BT , GHANI, A , COUGHLIN, CR , VAN HOVE, JLK , RICHTER, JW , CHRISTEN, HJ , GALLAGHER, R , ET AL (2016) PYRIDOXINE-DEPENDENT EPILEPSY: AN EXPANDING CLINICAL SPECTRUM.PEDIATRIC NEUROLOGY. VOL. 59. ISSUE . P. 6 -12 47 98% 2
2 STOCKLER, S , PLECKO, B , GOSPE, SM , COULTER-MACKIE, M , CONNOLLY, M , VAN KARNEBEEK, C , MERCIMEK-MAHMUTOGLU, S , HARTMANN, H , SCHARER, G , STRUIJS, E , ET AL (2011) PYRIDOXINE DEPENDENT EPILEPSY AND ANTIQUITIN DEFICIENCY CLINICAL AND MOLECULAR CHARACTERISTICS AND RECOMMENDATIONS FOR DIAGNOSIS, TREATMENT AND FOLLOW-UP.MOLECULAR GENETICS AND METABOLISM. VOL. 104. ISSUE 1-2. P. 48-60 67 68% 51
3 VAN KARNEBEEK, CDM , JAGGUMANTRI, S , (2015) CURRENT TREATMENT AND MANAGEMENT OF PYRIDOXINE-DEPENDENT EPILEPSY.CURRENT TREATMENT OPTIONS IN NEUROLOGY. VOL. 17. ISSUE 2. P. - 39 89% 0
4 BASURA, GJ , HAGLAND, SP , WILTSE, AM , GOSPE, SM , (2009) CLINICAL FEATURES AND THE MANAGEMENT OF PYRIDOXINE-DEPENDENT AND PYRIDOXINE-RESPONSIVE SEIZURES: REVIEW OF 63 NORTH AMERICAN CASES SUBMITTED TO A PATIENT REGISTRY.EUROPEAN JOURNAL OF PEDIATRICS. VOL. 168. ISSUE 6. P. 697 -704 32 97% 28
5 YANG, ZX , YANG, XL , WU, Y , WANG, JM , ZHANG, YH , XIONG, H , JIANG, YW , QIN, J , (2014) CLINICAL DIAGNOSIS, TREATMENT, AND ALDH7A1 MUTATIONS IN PYRIDOXINE-DEPENDENT EPILEPSY IN THREE CHINESE INFANTS.PLOS ONE. VOL. 9. ISSUE 3. P. - 28 93% 3
6 NASR, E , MAMAK, E , FEIGENBAUM, A , DONNER, EJ , MERCIMEK-MAHMUTOGLU, S , (2015) LONG-TERM TREATMENT OUTCOME OF TWO PATIENTS WITH PYRIDOXINE-DEPENDENT EPILEPSY CAUSED BY ALDH7A1 MUTATIONS: NORMAL NEUROCOGNITIVE OUTCOME.JOURNAL OF CHILD NEUROLOGY. VOL. 30. ISSUE 5. P. 648 -653 26 100% 0
7 SCHARER, G , BROCKER, C , VASILIOU, V , CREADON-SWINDELL, G , GALLAGHER, RC , SPECTOR, E , VAN HOVE, JLK , (2010) THE GENOTYPIC AND PHENOTYPIC SPECTRUM OF PYRIDOXINE-DEPENDENT EPILEPSY DUE TO MUTATIONS IN ALDH7A1.JOURNAL OF INHERITED METABOLIC DISEASE. VOL. 33. ISSUE 5. P. 571 -581 27 79% 30
8 TLILI, A , HENTATI, NH , CHAABANE, R , GARGOURI, A , FAKHFAKH, F , (2013) PYRIDOXINE-DEPENDENT EPILEPSY IN TUNISIA IS CAUSED BY A FOUNDER MISSENSE MUTATION OF THE ALDH7A1 GENE.GENE. VOL. 518. ISSUE 2. P. 242-245 22 96% 4
9 BOK, LA , MAURITS, NM , WILLEMSEN, MA , JAKOBS, C , TEUNE, LK , POLL-THE, BT , DE COO, IF , TOET, MC , HAGEBEUK, EE , BROUWER, OF , ET AL (2010) THE EEG RESPONSE TO PYRIDOXINE-IV NEITHER IDENTIFIES NOR EXCLUDES PYRIDOXINE-DEPENDENT EPILEPSY.EPILEPSIA. VOL. 51. ISSUE 12. P. 2406 -2411 25 89% 11
10 GOSPE, SM , (2002) PYRIDOXINE-DEPENDENT SEIZURES: FINDINGS FROM RECENT STUDIES POSE NEW QUESTIONS.PEDIATRIC NEUROLOGY. VOL. 26. ISSUE 3. P. 181-185 33 83% 33

Classes with closest relation at Level 1


Rank Class id link
1 9029 VITAMIN B 6//VITAMIN B 6 STATUS//VITAMIN B 6 DEFICIENCY
2 20140 PYRIDOXAL KINASE//PYRIDOXINE 5 PHOSPHATE OXIDASE//VITAMIN B 6
3 33017 METHYLCOBALAMIN//MILGAMMA//MILGAMMA COMPOSITUM
4 28022 SERINE BIOSYNTHESIS//SERINE DEFICIENCY//3 PHOSPHOGLYCERATE DEHYDROGENASE
5 18043 DOPA RESPONSIVE DYSTONIA//CEREBRAL FOLATE DEFICIENCY//SEGAWA DISEASE
6 23151 SOCIAL SEPARATION STRESS//NEONATAL CHICK//REGULAT METAB BEHAV
7 33156 NOSTOCHOPSIS LOBATUS//BARWON EPIDEMIOL BIOSTAT UNIT BARWON HLTH//BILIPIGMENTS
8 10778 WEST SYNDROME//INFANTILE SPASMS//HYPSARRHYTHMIA
9 21684 NONKETOTIC HYPERGLYCINEMIA//GLYCINE CLEAVAGE SYSTEM//NKH
10 17020 GLUTARIC ACIDURIA TYPE I//GLUTARIC ACIDURIA TYPE 1//L 2 HYDROXYGLUTARIC ACIDURIA

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