Class information for:
Level 3: KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
631 12928 34.1 63%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
631 3       KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE 12928
1475 2             THIAMINE//THIAMINE DEFICIENCY//WERNICKES ENCEPHALOPATHY 7673
2074 2             KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE 5255

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KYNURENINE authKW 657946 3% 65% 431
2 NEOPTERIN authKW 636913 4% 52% 515
3 INDOLEAMINE 2 3 DIOXYGENASE authKW 583142 3% 68% 364
4 KYNURENIC ACID authKW 552657 3% 66% 357
5 THIAMINE authKW 487387 3% 52% 401
6 THIAMINE DEFICIENCY authKW 462092 2% 80% 246
7 VITAMIN B 6 authKW 368709 3% 41% 381
8 WERNICKES ENCEPHALOPATHY authKW 352306 1% 83% 180
9 QUINOLINIC ACID authKW 279411 2% 44% 268
10 KYNURENINE PATHWAY authKW 254509 1% 79% 137

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Nutrition & Dietetics 21916 11% 1% 1467
2 Biochemistry & Molecular Biology 6450 22% 0% 2857
3 Neurosciences 3621 12% 0% 1567
4 Chemistry, Analytical 2178 7% 0% 910
5 Biophysics 1587 5% 0% 661
6 Clinical Neurology 1365 6% 0% 782
7 Food Science & Technology 1072 4% 0% 577
8 Immunology 996 6% 0% 790
9 Medicine, Research & Experimental 946 4% 0% 568
10 Pharmacology & Pharmacy 889 8% 0% 976

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN CULTU 97638 1% 47% 88
2 MED CHEM BIOCHEM FRITZ PREGL STR 3 69905 0% 74% 40
3 MED CHEM BIOCHEM 60293 1% 14% 186
4 LEHRSTUHL ORGAN CHEM BIOCHEM 53147 1% 34% 67
5 LIFE STYLE STUDIES 50082 0% 56% 38
6 PHYSIOL ANAT NEUROSCI 42865 0% 37% 49
7 CENT BLOOD TRANSFUS IMMUNOL 37235 0% 53% 30
8 GERONTOL METAB CARE 34792 0% 51% 29
9 INFORMAT CLIN MED 25936 0% 32% 34
10 MARYLAND PSYCHIAT 25188 1% 11% 101

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PTERIDINES 133005 1% 37% 151
2 INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH 30492 1% 8% 158
3 JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY 28918 1% 7% 180
4 JOURNAL OF NUTRITION 8786 2% 2% 226
5 JOURNAL OF MICRONUTRIENT ANALYSIS 7506 0% 15% 21
6 AMERICAN JOURNAL OF CLINICAL NUTRITION 5010 1% 1% 171
7 METABOLIC BRAIN DISEASE 4753 0% 4% 54
8 ALCOHOL AND ALCOHOLISM 3141 0% 2% 63
9 HUMAN NUTRITION-CLINICAL NUTRITION 2370 0% 6% 17
10 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 2219 1% 1% 111

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 KYNURENINE 657946 3% 65% 431 Search KYNURENINE Search KYNURENINE
2 NEOPTERIN 636913 4% 52% 515 Search NEOPTERIN Search NEOPTERIN
3 INDOLEAMINE 2 3 DIOXYGENASE 583142 3% 68% 364 Search INDOLEAMINE+2+3+DIOXYGENASE Search INDOLEAMINE+2+3+DIOXYGENASE
4 KYNURENIC ACID 552657 3% 66% 357 Search KYNURENIC+ACID Search KYNURENIC+ACID
5 THIAMINE 487387 3% 52% 401 Search THIAMINE Search THIAMINE
6 THIAMINE DEFICIENCY 462092 2% 80% 246 Search THIAMINE+DEFICIENCY Search THIAMINE+DEFICIENCY
7 VITAMIN B 6 368709 3% 41% 381 Search VITAMIN+B+6 Search VITAMIN+B+6
8 WERNICKES ENCEPHALOPATHY 352306 1% 83% 180 Search WERNICKES+ENCEPHALOPATHY Search WERNICKES+ENCEPHALOPATHY
9 QUINOLINIC ACID 279411 2% 44% 268 Search QUINOLINIC+ACID Search QUINOLINIC+ACID
10 KYNURENINE PATHWAY 254509 1% 79% 137 Search KYNURENINE+PATHWAY Search KYNURENINE+PATHWAY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 YEUNG, AWS , TERENTIS, AC , KING, NJC , THOMAS, SR , (2015) ROLE OF INDOLEAMINE 2,3-DIOXYGENASE IN HEALTH AND DISEASE.CLINICAL SCIENCE. VOL. 129. ISSUE 7. P. 601 -672 414 74% 13
2 LOVELACE, MD , VARNEY, B , SUNDARAM, G , LENNON, MJ , LIM, CK , JACOBS, K , GUILLEMIN, GJ , BREW, BJ , (2017) RECENT EVIDENCE FOR AN EXPANDED ROLE OF THE KYNURENINE PATHWAY OF TRYPTOPHAN METABOLISM IN NEUROLOGICAL DISEASES.NEUROPHARMACOLOGY. VOL. 112. ISSUE . P. 373 -388 130 80% 4
3 SCHWARCZ, R , BRUNO, JP , MUCHOWSKI, PJ , WU, HQ , (2012) KYNURENINES IN THE MAMMALIAN BRAIN: WHEN PHYSIOLOGY MEETS PATHOLOGY.NATURE REVIEWS NEUROSCIENCE. VOL. 13. ISSUE 7. P. 465 -477 163 84% 261
4 VECSEI, L , SZALARDY, L , FULOP, F , TOLDI, J , (2013) KYNURENINES IN THE CNS: RECENT ADVANCES AND NEW QUESTIONS.NATURE REVIEWS DRUG DISCOVERY. VOL. 12. ISSUE 1. P. 64 -82 172 80% 107
5 FUJIGAKI, H , YAMAMOTO, Y , SAITO, K , (2017) L-TRYPTOPHAN-KYNURENINE PATHWAY ENZYMES ARE THERAPEUTIC TARGET FOR NEUROPSYCHIATRIC DISEASES: FOCUS ON CELL TYPE DIFFERENCES.NEUROPHARMACOLOGY. VOL. 112. ISSUE . P. 264 -274 131 81% 1
6 WANG, QX , LIU, DX , SONG, P , ZOU, MH , (2015) TRYPTOPHAN-KYNURENINE PATHWAY IS DYSREGULATED IN INFLAMMATION, AND IMMUNE ACTIVATION.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 20. ISSUE . P. 1116 -1143 160 82% 13
7 ABBAS, CA , SIBIRNY, AA , (2011) GENETIC CONTROL OF BIOSYNTHESIS AND TRANSPORT OF RIBOFLAVIN AND FLAVIN NUCLEOTIDES AND CONSTRUCTION OF ROBUST BIOTECHNOLOGICAL PRODUCERS.MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS. VOL. 75. ISSUE 2. P. 321 -+ 201 57% 81
8 STRASSER, B , BECKER, K , FUCHS, D , GOSTNER, JM , (2017) KYNURENINE PATHWAY METABOLISM AND IMMUNE ACTIVATION: PERIPHERAL MEASUREMENTS IN PSYCHIATRIC AND CO-MORBID CONDITIONS.NEUROPHARMACOLOGY. VOL. 112. ISSUE . P. 286 -296 91 81% 1
9 OCAMPO, JR , HUITRON, RL , GONZALEZ-ESQUIVEL, D , UGALDE-MUNIZ, P , JIMENEZ-ANGUIANO, A , PINEDA, B , PEDRAZA-CHAVERRI, J , RIOS, C , DE LA CRUZ, VP , (2014) KYNURENINES WITH NEUROACTIVE AND REDOX PROPERTIES: RELEVANCE TO AGING AND BRAIN DISEASES.OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. VOL. . ISSUE . P. - 161 75% 6
10 O'FARRELL, K , HARKIN, A , (2017) STRESS-RELATED REGULATION OF THE KYNURENINE PATHWAY: RELEVANCE TO NEUROPSYCHIATRIC AND DEGENERATIVE DISORDERS.NEUROPHARMACOLOGY. VOL. 112. ISSUE . P. 307 -323 121 58% 1

Classes with closest relation at Level 3


Rank Class id link
1 502 HOMOCYSTEINE//FOLATE//FOLIC ACID
2 278 CORYNEBACTERIUM GLUTAMICUM//ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//BIOCHEMISTRY & MOLECULAR BIOLOGY
3 389 PEROXISOME//CARNITINE//JOURNAL OF INHERITED METABOLIC DISEASE
4 603 HUNTINGTONS DISEASE//SPINOCEREBELLAR ATAXIA//POLYGLUTAMINE
5 385 MICROGLIA//MAGNETIC RESONANCE SPECTROSCOPY//LITHIUM
6 366 CROCIN//SAFRANAL//CROCUS SATIVUS L
7 285 ERDOSTEINE//PEROXIREDOXIN//GLUTATHIONE
8 648 ADVANCED GLYCATION END PRODUCTS//HMGB1//METHYLGLYOXAL
9 630 HEPATIC ENCEPHALOPATHY//ASYMMETRIC DIMETHYLARGININE//HYPERAMMONEMIA
10 100 NEUROSCIENCES//METABOTROPIC GLUTAMATE RECEPTOR//HIPPOCAMPUS

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