Class information for:
Level 3: HUNTINGTONS DISEASE//SPINOCEREBELLAR ATAXIA//POLYGLUTAMINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
603 14359 42.5 81%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
603 3       HUNTINGTONS DISEASE//SPINOCEREBELLAR ATAXIA//POLYGLUTAMINE 14359
1645 2             HUNTINGTONS DISEASE//HUNTINGTIN//POLYGLUTAMINE 6932
1711 2             SPINOCEREBELLAR ATAXIA//HEREDITARY SPASTIC PARAPLEGIA//FRIEDREICHS ATAXIA 6674
3956 2             RKIP//RAF KINASE INHIBITOR PROTEIN//HIPPOCAMPAL CHOLINERGIC NEUROSTIMULATING PEPTIDE 753

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 HUNTINGTONS DISEASE authKW 2792091 16% 58% 2267
2 SPINOCEREBELLAR ATAXIA authKW 615606 3% 72% 400
3 POLYGLUTAMINE authKW 533393 3% 66% 383
4 HUNTINGTIN authKW 478738 2% 74% 304
5 HEREDITARY SPASTIC PARAPLEGIA authKW 454237 2% 82% 262
6 FRIEDREICHS ATAXIA authKW 401488 2% 76% 249
7 FRIEDREICH ATAXIA authKW 354626 1% 83% 201
8 MACHADO JOSEPH DISEASE authKW 351163 1% 86% 192
9 FRATAXIN authKW 322061 1% 87% 175
10 3 NITROPROPIONIC ACID authKW 305805 2% 61% 237

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Clinical Neurology 60274 29% 1% 4143
2 Neurosciences 34378 30% 0% 4265
3 Genetics & Heredity 23266 18% 1% 2543
4 Biochemistry & Molecular Biology 7720 23% 0% 3264
5 Cell Biology 1918 8% 0% 1141
6 Neuroimaging 1421 1% 0% 198
7 Psychiatry 1206 4% 0% 636
8 Pathology 823 3% 0% 410
9 Biophysics 309 3% 0% 410
10 Pediatrics 261 3% 0% 366

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 NEUROL 103135 25% 1% 3521
2 MOL MED THER EUT 90056 1% 23% 189
3 ZYTOBIOL ZYTOPATHOL 82448 0% 63% 62
4 GENET CYTOGENET 61826 1% 32% 91
5 UNIGENE 57399 0% 52% 52
6 HUNTINGTON NRW 37071 0% 73% 24
7 BRUCE LEFROY GENET HLTH 35409 0% 35% 48
8 GENET CYTOGENET EMBRYOL 34168 0% 34% 48
9 ZYTOBIOL 32380 0% 51% 30
10 NEUROGENET RARE DIS 32313 0% 89% 17

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN MOLECULAR GENETICS 64080 4% 6% 545
2 CEREBELLUM 55483 1% 17% 154
3 MOVEMENT DISORDERS 36548 2% 5% 337
4 NEUROBIOLOGY OF DISEASE 27769 2% 6% 220
5 NEUROGENETICS 21265 1% 13% 78
6 NEUROLOGY 14133 3% 2% 383
7 JOURNAL OF NEUROLOGY 13818 1% 3% 201
8 JOURNAL OF THE NEUROLOGICAL SCIENCES 12663 2% 2% 249
9 ARCHIVES OF NEUROLOGY 10733 1% 3% 185
10 BRAIN 10020 1% 3% 175

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 HUNTINGTONS DISEASE 2792091 16% 58% 2267 Search HUNTINGTONS+DISEASE Search HUNTINGTONS+DISEASE
2 SPINOCEREBELLAR ATAXIA 615606 3% 72% 400 Search SPINOCEREBELLAR+ATAXIA Search SPINOCEREBELLAR+ATAXIA
3 POLYGLUTAMINE 533393 3% 66% 383 Search POLYGLUTAMINE Search POLYGLUTAMINE
4 HUNTINGTIN 478738 2% 74% 304 Search HUNTINGTIN Search HUNTINGTIN
5 HEREDITARY SPASTIC PARAPLEGIA 454237 2% 82% 262 Search HEREDITARY+SPASTIC+PARAPLEGIA Search HEREDITARY+SPASTIC+PARAPLEGIA
6 FRIEDREICHS ATAXIA 401488 2% 76% 249 Search FRIEDREICHS+ATAXIA Search FRIEDREICHS+ATAXIA
7 FRIEDREICH ATAXIA 354626 1% 83% 201 Search FRIEDREICH+ATAXIA Search FRIEDREICH+ATAXIA
8 MACHADO JOSEPH DISEASE 351163 1% 86% 192 Search MACHADO+JOSEPH+DISEASE Search MACHADO+JOSEPH+DISEASE
9 FRATAXIN 322061 1% 87% 175 Search FRATAXIN Search FRATAXIN
10 3 NITROPROPIONIC ACID 305805 2% 61% 237 Search 3+NITROPROPIONIC+ACID Search 3+NITROPROPIONIC+ACID

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ZUCCATO, C , VALENZA, M , CATTANEO, E , (2010) MOLECULAR MECHANISMS AND POTENTIAL THERAPEUTICAL TARGETS IN HUNTINGTON'S DISEASE.PHYSIOLOGICAL REVIEWS. VOL. 90. ISSUE 3. P. 905-981 461 72% 309
2 FIGIEL, M , SZLACHCIC, WJ , SWITONSKI, PM , GABKA, A , KRZYZOSIAK, WJ , (2012) MOUSE MODELS OF POLYGLUTAMINE DISEASES: REVIEW AND DATA TABLE. PART I.MOLECULAR NEUROBIOLOGY. VOL. 46. ISSUE 2. P. 393-429 299 82% 12
3 SANTOS, R , LEFEVRE, S , SLIWA, D , SEGUIN, A , CAMADRO, JM , LESUISSE, E , (2010) FRIEDREICH ATAXIA: MOLECULAR MECHANISMS, REDOX CONSIDERATIONS, AND THERAPEUTIC OPPORTUNITIES.ANTIOXIDANTS & REDOX SIGNALING. VOL. 13. ISSUE 5. P. 651 -690 264 87% 59
4 BAUER, PO , NUKINA, N , (2009) THE PATHOGENIC MECHANISMS OF POLYGLUTAMINE DISEASES AND CURRENT THERAPEUTIC STRATEGIES.JOURNAL OF NEUROCHEMISTRY. VOL. 110. ISSUE 6. P. 1737 -1765 278 80% 94
5 GIL, JM , REGO, AC , (2008) MECHANISMS OF NEURODEGENERATION IN HUNTINGTON'S DISEASE.EUROPEAN JOURNAL OF NEUROSCIENCE. VOL. 27. ISSUE 11. P. 2803 -2820 215 82% 200
6 JONES, L , HUGHES, A , (2011) PATHOGENIC MECHANISMS IN HUNTINGTON'S DISEASE.PATHOPHYSIOLOGY, PHARMACOLOGY, AND BIOCHEMISTRY OF DYSKINESIA. VOL. 98. ISSUE . P. 373 -418 263 82% 10
7 ROSS, CA , TABRIZI, SJ , (2011) HUNTINGTON'S DISEASE: FROM MOLECULAR PATHOGENESIS TO CLINICAL TREATMENT.LANCET NEUROLOGY. VOL. 10. ISSUE 1. P. 83-98 127 84% 395
8 SCHOLS, L , PAULSON, H , AUBURGER, G , KERMER, P , JEN, JC , SEIDEL, K , KORF, HW , DELLER, T , RUB, U , (2013) CLINICAL FEATURES, NEUROGENETICS AND NEUROPATHOLOGY OF THE POLYGLUTAMINE SPINOCEREBELLAR ATAXIAS TYPE 1, 2, 3, 6 AND 7.PROGRESS IN NEUROBIOLOGY. VOL. 104. ISSUE . P. 38 -66 221 72% 48
9 COSTA, MD , PAULSON, HL , (2012) TOWARD UNDERSTANDING MACHADO-JOSEPH DISEASE.PROGRESS IN NEUROBIOLOGY. VOL. 97. ISSUE 2. P. 239 -257 193 89% 44
10 SEIDEL, K , SISWANTO, S , BRUNT, ERP , DEN DUNNEN, W , KORF, HW , RUB, U , (2012) BRAIN PATHOLOGY OF SPINOCEREBELLAR ATAXIAS.ACTA NEUROPATHOLOGICA. VOL. 124. ISSUE 1. P. 1 -21 168 92% 75

Classes with closest relation at Level 3


Rank Class id link
1 124 PARKINSONS DISEASE//MOVEMENT DISORDERS//DEEP BRAIN STIMULATION
2 49 ALZHEIMERS DISEASE//AMYOTROPHIC LATERAL SCLEROSIS//DEMENTIA
3 512 BRCA1//BRCA2//FANCONI ANEMIA
4 631 KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE
5 271 MITOCHONDRIA//MITOCHONDRIAL GENOME//MITOCHONDRIAL DNA PART A
6 658 COENZYME Q10//UBIQUINONE//COENZYME Q
7 268 NEUROTROPHINS//BRAIN DERIVED NEUROTROPHIC FACTOR//BDNF
8 204 PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE
9 673 SIDEROPHORE//COLICIN//UREASE
10 262 AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR

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