Class information for:
Level 2: HUNTINGTONS DISEASE//HUNTINGTIN//POLYGLUTAMINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1645 6932 48.6 81%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
603 3       HUNTINGTONS DISEASE//SPINOCEREBELLAR ATAXIA//POLYGLUTAMINE 14359
1645 2             HUNTINGTONS DISEASE//HUNTINGTIN//POLYGLUTAMINE 6932
377 1                   HUNTINGTONS DISEASE//HUNTINGTIN//POLYGLUTAMINE 3565
1749 1                   HUNTINGTONS DISEASE//PREDICTIVE TESTING//JUVENILE HUNTINGTON DISEASE 2504
19391 1                   3 NITROPROPIONIC ACID//3 NP//MITOCHONDRIAL TOXIN 507
23161 1                   2 NITROPROPANE//INDOSPICINE//INDIGOFERA SUFFRUTICOSA 356

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 HUNTINGTONS DISEASE authKW 5676569 32% 57% 2245
2 HUNTINGTIN authKW 972818 4% 73% 301
3 POLYGLUTAMINE authKW 800977 5% 56% 326
4 3 NITROPROPIONIC ACID authKW 628615 3% 61% 236
5 POLYGLUTAMINE DISEASE authKW 219199 1% 48% 103
6 ATAXIN 3 authKW 217563 1% 70% 71
7 HUNTINGTON authKW 193851 1% 48% 91
8 MOL MED THER EUT address 184972 3% 22% 188
9 PREDICTIVE TESTING authKW 136964 1% 38% 82
10 MUTANT HUNTINGTIN authKW 97258 0% 82% 27

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Neurosciences 28336 38% 0% 2627
2 Clinical Neurology 13373 20% 0% 1395
3 Genetics & Heredity 9912 17% 0% 1160
4 Biochemistry & Molecular Biology 4613 25% 0% 1710
5 Psychiatry 1231 6% 0% 408
6 Cell Biology 834 8% 0% 531
7 Neuroimaging 370 1% 0% 73
8 Psychology 229 2% 0% 120
9 Behavioral Sciences 225 2% 0% 122
10 Biophysics 195 3% 0% 214

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 MOL MED THER EUT 184972 3% 22% 188
2 HUNTINGTON NRW 76840 0% 73% 24
3 NEUROGENET RARE DIS 66969 0% 89% 17
4 TRANSLAT NEUROENDOCRINE UNIT 53920 0% 58% 21
5 STRUCT NEUROPATHOL 45686 1% 27% 38
6 NEUROL 42579 23% 1% 1576
7 TAUBE KORET HUNTINGTONS DIS 41086 0% 67% 14
8 HUNTINGTONS DIS CLIN 40979 0% 85% 11
9 NEUROIMAGING AGING NEURODEGENERAT DIS 32419 0% 82% 9
10 HUNTINGTONS DIS FORUM 30821 0% 100% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN MOLECULAR GENETICS 54658 5% 4% 349
2 NEUROBIOLOGY OF DISEASE 47889 3% 5% 200
3 MOVEMENT DISORDERS 21636 3% 3% 180
4 MOLECULAR NEURODEGENERATION 6133 0% 5% 28
5 JOURNAL OF MEDICAL GENETICS 4978 1% 1% 82
6 CLINICAL GENETICS 4485 1% 1% 73
7 EXPERIMENTAL NEUROLOGY 4028 1% 1% 94
8 BRAIN 3297 1% 1% 70
9 JOURNAL OF GENETIC COUNSELING 3172 0% 3% 22
10 JOURNAL OF NEUROCHEMISTRY 3147 2% 1% 126

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 HUNTINGTONS DISEASE 5676569 32% 57% 2245 Search HUNTINGTONS+DISEASE Search HUNTINGTONS+DISEASE
2 HUNTINGTIN 972818 4% 73% 301 Search HUNTINGTIN Search HUNTINGTIN
3 POLYGLUTAMINE 800977 5% 56% 326 Search POLYGLUTAMINE Search POLYGLUTAMINE
4 3 NITROPROPIONIC ACID 628615 3% 61% 236 Search 3+NITROPROPIONIC+ACID Search 3+NITROPROPIONIC+ACID
5 POLYGLUTAMINE DISEASE 219199 1% 48% 103 Search POLYGLUTAMINE+DISEASE Search POLYGLUTAMINE+DISEASE
6 ATAXIN 3 217563 1% 70% 71 Search ATAXIN+3 Search ATAXIN+3
7 HUNTINGTON 193851 1% 48% 91 Search HUNTINGTON Search HUNTINGTON
8 PREDICTIVE TESTING 136964 1% 38% 82 Search PREDICTIVE+TESTING Search PREDICTIVE+TESTING
9 MUTANT HUNTINGTIN 97258 0% 82% 27 Search MUTANT+HUNTINGTIN Search MUTANT+HUNTINGTIN
10 R6 2 MICE 90185 0% 79% 26 Search R6+2+MICE Search R6+2+MICE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ZUCCATO, C , VALENZA, M , CATTANEO, E , (2010) MOLECULAR MECHANISMS AND POTENTIAL THERAPEUTICAL TARGETS IN HUNTINGTON'S DISEASE.PHYSIOLOGICAL REVIEWS. VOL. 90. ISSUE 3. P. 905-981 461 72% 309
2 GIL, JM , REGO, AC , (2008) MECHANISMS OF NEURODEGENERATION IN HUNTINGTON'S DISEASE.EUROPEAN JOURNAL OF NEUROSCIENCE. VOL. 27. ISSUE 11. P. 2803 -2820 215 82% 200
3 BAUER, PO , NUKINA, N , (2009) THE PATHOGENIC MECHANISMS OF POLYGLUTAMINE DISEASES AND CURRENT THERAPEUTIC STRATEGIES.JOURNAL OF NEUROCHEMISTRY. VOL. 110. ISSUE 6. P. 1737 -1765 260 74% 94
4 FIGIEL, M , SZLACHCIC, WJ , SWITONSKI, PM , GABKA, A , KRZYZOSIAK, WJ , (2012) MOUSE MODELS OF POLYGLUTAMINE DISEASES: REVIEW AND DATA TABLE. PART I.MOLECULAR NEUROBIOLOGY. VOL. 46. ISSUE 2. P. 393-429 275 76% 12
5 JONES, L , HUGHES, A , (2011) PATHOGENIC MECHANISMS IN HUNTINGTON'S DISEASE.PATHOPHYSIOLOGY, PHARMACOLOGY, AND BIOCHEMISTRY OF DYSKINESIA. VOL. 98. ISSUE . P. 373 -418 263 82% 10
6 ROSS, CA , TABRIZI, SJ , (2011) HUNTINGTON'S DISEASE: FROM MOLECULAR PATHOGENESIS TO CLINICAL TREATMENT.LANCET NEUROLOGY. VOL. 10. ISSUE 1. P. 83-98 127 84% 395
7 POULADI, MA , MORTON, AJ , HAYDEN, MR , (2013) CHOOSING AN ANIMAL MODEL FOR THE STUDY OF HUNTINGTON'S DISEASE.NATURE REVIEWS NEUROSCIENCE. VOL. 14. ISSUE 10. P. 708-721 162 88% 73
8 ROZE, E , BONNET, C , BETUING, S , CABOCHE, J , (2010) HUNTINGTON'S DISEASE.DISEASES OF DNA REPAIR. VOL. 685. ISSUE . P. 45 -63 234 85% 23
9 BATES, GP , DORSEY, R , GUSELLA, JF , HAYDEN, MR , KAY, C , LEAVITT, BR , NANCE, M , ROSS, CA , SCAHILL, RI , WETZEL, R , ET AL (2015) HUNTINGTON DISEASE.NATURE REVIEWS DISEASE PRIMERS. VOL. 1. ISSUE . P. - 179 83% 16
10 SAUDOU, F , HUMBERT, S , (2016) THE BIOLOGY OF HUNTINGTIN.NEURON. VOL. 89. ISSUE 5. P. 910 -926 126 87% 10

Classes with closest relation at Level 2


Rank Class id link
1 1711 SPINOCEREBELLAR ATAXIA//HEREDITARY SPASTIC PARAPLEGIA//FRIEDREICHS ATAXIA
2 3766 MINOCYCLINE//BLACK THYROID//COL 3
3 1039 GENETIC TESTING//BIOBANK//JOURNAL OF GENETIC COUNSELING
4 3956 RKIP//RAF KINASE INHIBITOR PROTEIN//HIPPOCAMPAL CHOLINERGIC NEUROSTIMULATING PEPTIDE
5 2074 KYNURENINE//NEOPTERIN//INDOLEAMINE 2 3 DIOXYGENASE
6 332 PARKINSONS DISEASE//ALPHA SYNUCLEIN//PARKIN
7 1384 GDNF//GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR//NEURAL TRANSPLANTATION
8 699 AMYOTROPHIC LATERAL SCLEROSIS//FRONTOTEMPORAL DEMENTIA//ALS
9 677 PROTEASOME//UBIQUITIN//PROTEASOME INHIBITOR
10 2003 MYOTONIC DYSTROPHY//MYOTONIA//MYOTONIC DYSTROPHY TYPE 1

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