Class information for:
Level 1: HUNTINGTONS DISEASE//HUNTINGTIN//POLYGLUTAMINE

Basic class information

Class id #P Avg. number of
references
Database coverage
of references
377 3565 58.7 92%



Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes

The table includes all classes above and classes immediately below the current class.



Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
603 3       HUNTINGTONS DISEASE//SPINOCEREBELLAR ATAXIA//POLYGLUTAMINE 14359
1645 2             HUNTINGTONS DISEASE//HUNTINGTIN//POLYGLUTAMINE 6932
377 1                   HUNTINGTONS DISEASE//HUNTINGTIN//POLYGLUTAMINE 3565

Terms with highest relevance score



rank Term termType Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with term
in class
1 HUNTINGTONS DISEASE authKW 2264893 29% 26% 1017
2 HUNTINGTIN authKW 1708256 8% 70% 286
3 POLYGLUTAMINE authKW 1510646 9% 55% 321
4 ATAXIN 3 authKW 423176 2% 70% 71
5 POLYGLUTAMINE DISEASE authKW 355137 3% 44% 94
6 MUTANT HUNTINGTIN authKW 189165 1% 82% 27
7 HUNTINGTON authKW 180705 2% 34% 63
8 MOL MED THER EUT address 174728 4% 16% 131
9 ATAXIN 1 authKW 164566 1% 62% 31
10 R6 2 MICE authKW 162174 1% 76% 25

Web of Science journal categories



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with term
in class
1 Neurosciences 21155 45% 0% 1606
2 Biochemistry & Molecular Biology 7677 40% 0% 1425
3 Genetics & Heredity 5491 17% 0% 617
4 Cell Biology 1915 14% 0% 484
5 Clinical Neurology 1039 9% 0% 317
6 Biophysics 455 5% 0% 185
7 Medicine, Research & Experimental 176 4% 0% 137
8 Pathology 52 2% 0% 65
9 Biochemical Research Methods 38 2% 0% 75
10 Cell & Tissue Engineering 26 0% 0% 12

Address terms



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 MOL MED THER EUT 174728 4% 16% 131
2 STRUCT NEUROPATHOL 88906 1% 27% 38
3 TAUBE KORET HUNTINGTONS DIS 79916 0% 67% 14
4 TRANSLAT NEUROENDOCRINE UNIT 77053 1% 50% 18
5 HUNTINGTONS DIS FORUM 59944 0% 100% 7
6 DEANE 54526 0% 58% 11
7 U1005 47939 0% 40% 14
8 CAG REPEAT DIS 46235 0% 60% 9
9 NEURONAL SURVIVAL UNIT 45524 1% 20% 27
10 BRAIN DIS BIOMARKER UNIT 42152 0% 62% 8

Journals



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 HUMAN MOLECULAR GENETICS 88726 9% 3% 318
2 NEUROBIOLOGY OF DISEASE 70721 5% 5% 174
3 MOLECULAR NEURODEGENERATION 8794 1% 4% 24
4 JOURNAL OF NEUROSCIENCE 5054 4% 0% 144
5 MOLECULAR AND CELLULAR NEUROSCIENCE 3089 1% 1% 32
6 CLINICAL NEUROSCIENCE RESEARCH 3025 0% 4% 9
7 NEURON 2970 2% 1% 54
8 BRAIN RESEARCH BULLETIN 2653 1% 1% 50
9 JOURNAL OF NEUROCHEMISTRY 2634 2% 0% 82
10 EXPERIMENTAL NEUROLOGY 2404 1% 1% 52

Author Key Words



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with term
in class
LCSH search Wikipedia search
1 HUNTINGTONS DISEASE 2264893 29% 26% 1017 Search HUNTINGTONS+DISEASE Search HUNTINGTONS+DISEASE
2 HUNTINGTIN 1708256 8% 70% 286 Search HUNTINGTIN Search HUNTINGTIN
3 POLYGLUTAMINE 1510646 9% 55% 321 Search POLYGLUTAMINE Search POLYGLUTAMINE
4 ATAXIN 3 423176 2% 70% 71 Search ATAXIN+3 Search ATAXIN+3
5 POLYGLUTAMINE DISEASE 355137 3% 44% 94 Search POLYGLUTAMINE+DISEASE Search POLYGLUTAMINE+DISEASE
6 MUTANT HUNTINGTIN 189165 1% 82% 27 Search MUTANT+HUNTINGTIN Search MUTANT+HUNTINGTIN
7 HUNTINGTON 180705 2% 34% 63 Search HUNTINGTON Search HUNTINGTON
8 ATAXIN 1 164566 1% 62% 31 Search ATAXIN+1 Search ATAXIN+1
9 R6 2 MICE 162174 1% 76% 25 Search R6+2+MICE Search R6+2+MICE
10 R6 1 145579 0% 100% 17 Search R6+1 Search R6+1

Core articles

The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.



Rank Reference # ref. in
cl.
Shr. of ref. in
cl.
Citations
1 ZUCCATO, C , VALENZA, M , CATTANEO, E , (2010) MOLECULAR MECHANISMS AND POTENTIAL THERAPEUTICAL TARGETS IN HUNTINGTON'S DISEASE.PHYSIOLOGICAL REVIEWS. VOL. 90. ISSUE 3. P. 905-981 390 61% 309
2 BAUER, PO , NUKINA, N , (2009) THE PATHOGENIC MECHANISMS OF POLYGLUTAMINE DISEASES AND CURRENT THERAPEUTIC STRATEGIES.JOURNAL OF NEUROCHEMISTRY. VOL. 110. ISSUE 6. P. 1737 -1765 254 73% 94
3 FIGIEL, M , SZLACHCIC, WJ , SWITONSKI, PM , GABKA, A , KRZYZOSIAK, WJ , (2012) MOUSE MODELS OF POLYGLUTAMINE DISEASES: REVIEW AND DATA TABLE. PART I.MOLECULAR NEUROBIOLOGY. VOL. 46. ISSUE 2. P. 393-429 270 74% 12
4 JONES, L , HUGHES, A , (2011) PATHOGENIC MECHANISMS IN HUNTINGTON'S DISEASE.PATHOPHYSIOLOGY, PHARMACOLOGY, AND BIOCHEMISTRY OF DYSKINESIA. VOL. 98. ISSUE . P. 373 -418 248 78% 10
5 SZLACHCIC, WJ , GABKA, A , KRZYZOSIAK, WJ , FIGIEL, M , SWITONSKI, PM , (2012) MOUSE MODELS OF POLYGLUTAMINE DISEASES IN THERAPEUTIC APPROACHES: REVIEW AND DATA TABLE. PART II.MOLECULAR NEUROBIOLOGY. VOL. 46. ISSUE 2. P. 430 -466 262 67% 7
6 SAUDOU, F , HUMBERT, S , (2016) THE BIOLOGY OF HUNTINGTIN.NEURON. VOL. 89. ISSUE 5. P. 910 -926 120 83% 10
7 POULADI, MA , MORTON, AJ , HAYDEN, MR , (2013) CHOOSING AN ANIMAL MODEL FOR THE STUDY OF HUNTINGTON'S DISEASE.NATURE REVIEWS NEUROSCIENCE. VOL. 14. ISSUE 10. P. 708-721 139 75% 73
8 WEBER, JJ , SOWA, AS , BINDER, T , HUBENER, J , (2014) FROM PATHWAYS TO TARGETS: UNDERSTANDING THE MECHANISMS BEHIND POLYGLUTAMINE DISEASE.BIOMED RESEARCH INTERNATIONAL. VOL. . ISSUE . P. - 198 71% 1
9 GIL, JM , REGO, AC , (2008) MECHANISMS OF NEURODEGENERATION IN HUNTINGTON'S DISEASE.EUROPEAN JOURNAL OF NEUROSCIENCE. VOL. 27. ISSUE 11. P. 2803 -2820 170 65% 200
10 WETZEL, R , (2012) PHYSICAL CHEMISTRY OF POLYGLUTAMINE: INTRIGUING TALES OF A MONOTONOUS SEQUENCE.JOURNAL OF MOLECULAR BIOLOGY. VOL. 421. ISSUE 4-5. P. 466-490 140 77% 62

Classes with closest relation at Level 1



Rank Class id link
1 1749 HUNTINGTONS DISEASE//PREDICTIVE TESTING//JUVENILE HUNTINGTON DISEASE
2 20207 KENNEDYS DISEASE//SPINAL AND BULBAR MUSCULAR ATROPHY//SBMA
3 19391 3 NITROPROPIONIC ACID//3 NP//MITOCHONDRIAL TOXIN
4 2557 SPINOCEREBELLAR ATAXIA//MACHADO JOSEPH DISEASE//SCA2
5 34141 NEURONAL INTRANUCLEAR INCLUSION DISEASE//INTRANUCLEAR INCLUSION BODY DISEASE//NEURONAL INTRANUCLEAR HYALINE INCLUSION DISEASE
6 35314 UBIQUILIN//UBIQUILIN 1//UBQLN1
7 16834 SECT GENE STRUCT DIS//REPEAT INSTABILITY//MUTS BETA
8 24494 OCULOPHARYNGEAL MUSCULAR DYSTROPHY//PABPN1//OPMD
9 11831 SUP35//YEAST PRION//URE2P
10 18772 UCH L1//UBIQUITIN CARBOXY TERMINAL HYDROLASE L1//DEGENERAT NEUROL DIS

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