Class information for:
Level 2: PARKINSONS DISEASE//ALPHA SYNUCLEIN//PARKIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
332 18089 47.5 82%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
124 3       PARKINSONS DISEASE//MOVEMENT DISORDERS//DEEP BRAIN STIMULATION 67777
332 2             PARKINSONS DISEASE//ALPHA SYNUCLEIN//PARKIN 18089
477 1                   ALPHA SYNUCLEIN//SYNUCLEIN//LEWY BODY 3392
3681 1                   MPTP//MPP//1 METHYL 4 PHENYL 1 2 3 6 TETRAHYDROPYRIDINE 1932
4709 1                   PARKIN//PINK1//PARK2 1740
4921 1                   PARKINSONS DISEASE//MANEB//MOL CELLULAR TOXICOL HUMAN PLICAT 1703
4990 1                   MONOAMINE OXIDASE//MAO B//MONOAMINE OXIDASE B 1691
6773 1                   LRRK2//LEUCINE RICH REPEAT KINASE 2//LEUCINE RICH REPEAT KINASE 2 LRRK2 1445
7381 1                   NEUROMELANIN//AMINOCHROME//DOPAMINE QUINONE 1373
7937 1                   SELEGILINE//RASAGILINE//DEPRENYL 1311
8954 1                   NEUROPHARMACOL SECT//MICROGLIA//PARKINSONS DISEASE 1201
17247 1                   DJ 1//PARK7//DJ 1 SUPERFAMILY 609
17570 1                   SALSOLINOL//1 2 3 4 TETRAHYDROISOQUINOLINE//1 BENZYL 1 2 3 4 TETRAHYDROISOQUINOLINE 593
24398 1                   ROTENONE//AAV ALPHA SYNUCLEIN//PYRIMIDOTRIAZINEDIONE DERIVATIVES 313
25950 1                   SKIN BARRIER NETWORK HUMAN OURCES DEV TEAM BK2//LEWY BODY INCLUSION//3 4 5 TRICAFFEOYLQUINIC ACID 267
29114 1                   PRAMIPEXOLE//PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE//TALIPEXOLE 192
29898 1                   3 4 DIHYDROXYPHENYLACETALDEHYDE//3 4 DIHYDROXYPHENYLGLYCOLALDEHYDE//DOPAL 178
31685 1                   AGING NEUROEPIDEMIOL GRP//1 3 BIS 2 CHLOROETHYL 1 NITROSOUREA//AMYOTROPHIC LATERAL SCLEROSIS MORTALITY 149

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 PARKINSONS DISEASE authKW 1873767 32% 19% 5775
2 ALPHA SYNUCLEIN authKW 1652123 9% 62% 1585
3 PARKIN authKW 707681 3% 80% 524
4 LRRK2 authKW 617837 2% 90% 407
5 MPTP authKW 427915 4% 40% 639
6 DJ 1 authKW 410431 2% 83% 294
7 PINK1 authKW 373432 1% 84% 265
8 SYNUCLEIN authKW 262979 1% 65% 239
9 MONOAMINE OXIDASE authKW 229824 2% 34% 401
10 SELEGILINE authKW 228125 1% 62% 218

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Neurosciences 84476 40% 1% 7290
2 Clinical Neurology 34809 20% 1% 3636
3 Biochemistry & Molecular Biology 13767 26% 0% 4703
4 Pharmacology & Pharmacy 5861 13% 0% 2328
5 Cell Biology 1850 7% 0% 1311
6 Geriatrics & Gerontology 1496 2% 0% 329
7 Chemistry, Medicinal 1441 3% 0% 619
8 Toxicology 1069 3% 0% 561
9 Biophysics 993 4% 0% 692
10 Genetics & Heredity 927 4% 0% 808

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 NEUROL 97792 21% 2% 3867
2 NEUROPHARMACOL SECT 66669 0% 48% 83
3 NEURODEGENERAT DIS 54347 2% 10% 329
4 NEUROGENET 43097 2% 8% 307
5 NEURODEGENERAT TORAT 40299 0% 43% 56
6 NEUROBIOL GENE THER Y 35456 0% 43% 49
7 EVE TOPF EXCELLENCE NEURODEGENERAT DIS 33879 0% 72% 28
8 FUNCT NEUROGENET 28550 0% 71% 24
9 CELL BIOL GENE EXP S UNIT 27015 0% 70% 23
10 NEURODEGENERAT EXPT THER EUT 25086 0% 35% 43

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOVEMENT DISORDERS 60728 3% 8% 487
2 PARKINSONISM & RELATED DISORDERS 58465 2% 12% 289
3 JOURNAL OF NEURAL TRANSMISSION-SUPPLEMENT 45823 1% 19% 147
4 JOURNAL OF NEURAL TRANSMISSION 31548 2% 7% 278
5 JOURNAL OF NEUROCHEMISTRY 30367 3% 3% 621
6 PARKINSONS DISEASE 25749 0% 19% 80
7 NEUROTOXICITY RESEARCH 17736 1% 10% 102
8 NEUROBIOLOGY OF DISEASE 16497 1% 5% 191
9 NEUROSCIENCE LETTERS 16363 3% 2% 563
10 JOURNAL OF PARKINSONS DISEASE 13893 0% 15% 56

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 PARKINSONS DISEASE 1873767 32% 19% 5775 Search PARKINSONS+DISEASE Search PARKINSONS+DISEASE
2 ALPHA SYNUCLEIN 1652123 9% 62% 1585 Search ALPHA+SYNUCLEIN Search ALPHA+SYNUCLEIN
3 PARKIN 707681 3% 80% 524 Search PARKIN Search PARKIN
4 LRRK2 617837 2% 90% 407 Search LRRK2 Search LRRK2
5 MPTP 427915 4% 40% 639 Search MPTP Search MPTP
6 DJ 1 410431 2% 83% 294 Search DJ+1 Search DJ+1
7 PINK1 373432 1% 84% 265 Search PINK1 Search PINK1
8 SYNUCLEIN 262979 1% 65% 239 Search SYNUCLEIN Search SYNUCLEIN
9 MONOAMINE OXIDASE 229824 2% 34% 401 Search MONOAMINE+OXIDASE Search MONOAMINE+OXIDASE
10 SELEGILINE 228125 1% 62% 218 Search SELEGILINE Search SELEGILINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CORTI, O , LESAGE, S , BRICE, A , (2011) WHAT GENETICS TELLS US ABOUT THE CAUSES AND MECHANISMS OF PARKINSON'S DISEASE.PHYSIOLOGICAL REVIEWS. VOL. 91. ISSUE 4. P. 1161-1218 546 82% 186
2 WIRDEFELDT, K , ADAMI, HO , COLE, P , TRICHOPOULOS, D , MANDEL, J , (2011) EPIDEMIOLOGY AND ETIOLOGY OF PARKINSON'S DISEASE: A REVIEW OF THE EVIDENCE.EUROPEAN JOURNAL OF EPIDEMIOLOGY. VOL. 26. ISSUE . P. S1-S58 463 78% 250
3 EXNER, N , LUTZ, AK , HAASS, C , WINKLHOFER, KF , (2012) MITOCHONDRIAL DYSFUNCTION IN PARKINSON'S DISEASE: MOLECULAR MECHANISMS AND PATHOPHYSIOLOGICAL CONSEQUENCES.EMBO JOURNAL. VOL. 31. ISSUE 14. P. 3038-3062 309 83% 184
4 ROCHET, JC , HAY, BA , GUO, M , (2012) MOLECULAR INSIGHTS INTO PARKINSON'S DISEASE.MOLECULAR BIOLOGY OF NEURODEGENERATIVE DISEASES. VOL. 107. ISSUE . P. 125 -188 391 85% 28
5 JELLINGER, K , (2012) THE ROLE OF ALPHA-SYNUCLEIN IN NEURODEGENERATION - AN UPDATE.TRANSLATIONAL NEUROSCIENCE. VOL. 3. ISSUE 2. P. 75 -122 523 71% 2
6 NUYTEMANS, K , THEUNS, J , CRUTS, M , VAN BROECKHOVEN, C , (2010) GENETIC ETIOLOGY OF PARKINSON DISEASE ASSOCIATED WITH MUTATIONS IN THE SNCA, PARK2, PINK1, PARK7, AND LRRK2 GENES: A MUTATION UPDATE.HUMAN MUTATION. VOL. 31. ISSUE 7. P. 763-780 272 96% 165
7 OTTOLINI, D , CALI, T , SZABO, I , BRINI, M , (2017) ALPHA-SYNUCLEIN AT THE INTRACELLULAR AND THE EXTRACELLULAR SIDE: FUNCTIONAL AND DYSFUNCTIONAL IMPLICATIONS.BIOLOGICAL CHEMISTRY. VOL. 398. ISSUE 1. P. 77 -100 225 81% 1
8 DIAS, V , JUNN, E , MOURADIAN, MM , (2013) THE ROLE OF OXIDATIVE STRESS IN PARKINSON'S DISEASE.JOURNAL OF PARKINSONS DISEASE. VOL. 3. ISSUE 4. P. 461-491 284 69% 133
9 ABDEL-SALAM, OME , (2014) THE PATHS TO NEURODEGENERATION IN GENETIC PARKINSON'S DISEASE.CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. VOL. 13. ISSUE 9. P. 1485 -1512 350 84% 6
10 PICKRELL, AM , YOULE, RJ , (2015) THE ROLES OF PINK1, PARKIN, AND MITOCHONDRIAL FIDELITY IN PARKINSON'S DISEASE.NEURON. VOL. 85. ISSUE 2. P. 257 -273 155 80% 125

Classes with closest relation at Level 2


Rank Class id link
1 166 PARKINSONS DISEASE//MOVEMENT DISORDERS//MULTIPLE SYSTEM ATROPHY
2 3389 PARAQUAT//DIQUAT//PARAQUAT POISONING
3 3368 BETA CARBOLINE//HARMINE//NORHARMAN
4 1384 GDNF//GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR//NEURAL TRANSPLANTATION
5 2077 HOMOVANILLIC ACID//TRACE AMINES//BETA PHENYLETHYLAMINE
6 1128 AUTOPHAGY//BECLIN 1//LC3
7 35 ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU
8 1645 HUNTINGTONS DISEASE//HUNTINGTIN//POLYGLUTAMINE
9 3395 PKAN//NBIA//PANTOTHENATE KINASE
10 2994 NRF2//KEAP1//ANTIOXIDANT RESPONSE ELEMENT

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