Class information for:
Level 1: MILDRONATE//MET 88//GAMMA BUTYROBETAINE HYDROXYLASE INHIBITOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
29850 179 28.9 60%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
389 3       PEROXISOME//CARNITINE//JOURNAL OF INHERITED METABOLIC DISEASE 30841
1504 2             CARNITINE//L CARNITINE//TRIMETAZIDINE 7543
29850 1                   MILDRONATE//MET 88//GAMMA BUTYROBETAINE HYDROXYLASE INHIBITOR 179

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MILDRONATE authKW 6496778 29% 73% 52
2 MET 88 authKW 1023535 3% 100% 6
3 GAMMA BUTYROBETAINE HYDROXYLASE INHIBITOR authKW 852946 3% 100% 5
4 MELDONIUM authKW 767642 5% 50% 9
5 3 2 2 2 TRIMETHYLHYDRAZINIUM PROPIONATE authKW 341178 1% 100% 2
6 GAMMA BUTYROBETAINE authKW 255875 3% 25% 6
7 LONG CHAIN ACYLCARNITINE authKW 227447 2% 33% 4
8 2 OXOGLUTARATE 2OG OXYGENASE authKW 170589 1% 100% 1
9 ADAPTED TO COLD TION authKW 170589 1% 100% 1
10 ANTI HYPERTROPHIC ACTION authKW 170589 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 535 33% 0% 59
2 Cardiac & Cardiovascular System 358 18% 0% 33
3 Virology 81 6% 0% 10
4 Chemistry, Medicinal 37 5% 0% 9
5 Toxicology 37 5% 0% 9
6 Medicine, General & Internal 32 8% 0% 14
7 Biochemical Research Methods 20 4% 0% 8
8 Chemistry, Analytical 12 5% 0% 9
9 Behavioral Sciences 11 2% 0% 4
10 Sport Sciences 10 2% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEM FREE RAD 170589 1% 100% 1
2 CHAIR INTERNAL DIS PEDIAT 170589 1% 100% 1
3 CHAIR THEORET CLIN BIOCHEM 170589 1% 100% 1
4 CHAIR THER YSTOMATOL 170589 1% 100% 1
5 EOC MED COMMISS 170589 1% 100% 1
6 METABOL CARDIOVASC DRUG DISCOVERY 170589 1% 100% 1
7 MYASNIKOV FGBU RUSSIAN CARDIOL 170589 1% 100% 1
8 PYATIGORSK STATE MEDICOPHARMACEUT 170589 1% 100% 1
9 UMR 866EQUIPE PHYSIOPATHOL DYSLIPIDEMIES 170589 1% 100% 1
10 SOCIAL SCI MANAGEMENT BUSINESS ADM 85294 1% 50% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RUSSIAN JOURNAL OF CARDIOLOGY 23263 4% 2% 8
2 VOPROSY VIRUSOLOGII 7575 6% 0% 10
3 MEDICINA-LITHUANIA 2896 2% 0% 4
4 KARDIOLOGIYA 2604 6% 0% 10
5 FUNDAMENTAL & CLINICAL PHARMACOLOGY 1338 2% 0% 4
6 INZINERINE EKONOMIKA-ENGINEERING ECONOMICS 1271 1% 0% 2
7 FARMAKOLOGIYA I TOKSIKOLOGIYA 1261 2% 0% 3
8 CNS DRUG REVIEWS 1045 1% 1% 1
9 BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 855 2% 0% 3
10 PHARMACOLOGICAL REPORTS 852 2% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MILDRONATE 6496778 29% 73% 52 Search MILDRONATE Search MILDRONATE
2 MET 88 1023535 3% 100% 6 Search MET+88 Search MET+88
3 GAMMA BUTYROBETAINE HYDROXYLASE INHIBITOR 852946 3% 100% 5 Search GAMMA+BUTYROBETAINE+HYDROXYLASE+INHIBITOR Search GAMMA+BUTYROBETAINE+HYDROXYLASE+INHIBITOR
4 MELDONIUM 767642 5% 50% 9 Search MELDONIUM Search MELDONIUM
5 3 2 2 2 TRIMETHYLHYDRAZINIUM PROPIONATE 341178 1% 100% 2 Search 3+2+2+2+TRIMETHYLHYDRAZINIUM+PROPIONATE Search 3+2+2+2+TRIMETHYLHYDRAZINIUM+PROPIONATE
6 GAMMA BUTYROBETAINE 255875 3% 25% 6 Search GAMMA+BUTYROBETAINE Search GAMMA+BUTYROBETAINE
7 LONG CHAIN ACYLCARNITINE 227447 2% 33% 4 Search LONG+CHAIN+ACYLCARNITINE Search LONG+CHAIN+ACYLCARNITINE
8 2 OXOGLUTARATE 2OG OXYGENASE 170589 1% 100% 1 Search 2+OXOGLUTARATE+2OG+OXYGENASE Search 2+OXOGLUTARATE+2OG+OXYGENASE
9 ADAPTED TO COLD TION 170589 1% 100% 1 Search ADAPTED+TO+COLD+TION Search ADAPTED+TO+COLD+TION
10 ANTI HYPERTROPHIC ACTION 170589 1% 100% 1 Search ANTI+HYPERTROPHIC+ACTION Search ANTI+HYPERTROPHIC+ACTION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DAMBROVA, M , MAKRECKA-KUKA, M , VILSKERSTS, R , MAKAROVA, E , KUKA, J , LIEPINSH, E , (2016) PHARMACOLOGICAL EFFECTS OF MELDONIUM: BIOCHEMICAL MECHANISMS AND BIOMARKERS OF CARDIOMETABOLIC ACTIVITY.PHARMACOLOGICAL RESEARCH. VOL. 113. ISSUE . P. 771 -780 41 65% 3
2 SCHOBERSBERGER, W , DUNNWALD, T , GMEINER, G , BLANK, C , (2017) STORY BEHIND MELDONIUM-FROM PHARMACOLOGY TO PERFORMANCE ENHANCEMENT: A NARRATIVE REVIEW.BRITISH JOURNAL OF SPORTS MEDICINE. VOL. 51. ISSUE 1. P. 22 -+ 37 69% 0
3 ZHU, Y , ZHANG, GY , ZHAO, J , LI, DS , YAN, XD , LIU, JF , LIU, XD , ZHAO, HB , XIA, JL , ZHANG, X , ET AL (2013) EFFICACY AND SAFETY OF MILDRONATE FOR ACUTE ISCHEMIC STROKE: A RANDOMIZED, DOUBLE-BLIND, ACTIVE-CONTROLLED PHASE II MULTICENTER TRIAL.CLINICAL DRUG INVESTIGATION. VOL. 33. ISSUE 10. P. 755-760 17 71% 5
4 SJAKSTE, N , GUTCAITS, A , KALVINSH, I , (2005) MILDRONATE: AN ANTIISCHERNIC DRUG FOR NEUROLOGICAL INDICATIONS.CNS DRUG REVIEWS. VOL. 11. ISSUE 2. P. 151-168 19 70% 24
5 ZHANG, J , CAI, LJ , YANG, J , ZHANG, QZ , PENG, WX , (2013) NONLINEAR PHARMACOKINETIC PROPERTIES OF MILDRONATE CAPSULES: A RANDOMIZED, OPEN-LABEL, SINGLE- AND MULTIPLE-DOSE STUDY IN HEALTHY VOLUNTEERS.FUNDAMENTAL & CLINICAL PHARMACOLOGY. VOL. 27. ISSUE 1. P. 120-128 11 73% 5
6 KUKA, J , VILSKERSTS, R , CIRULE, H , MAKRECKA, M , PUGOVICS, O , KALVINSH, I , DAMBROVA, M , LIEPINSH, E , (2012) THE CARDIOPROTECTIVE EFFECT OF MILDRONATE IS DIMINISHED AFTER CO-TREATMENT WITH L-CARNITINE.JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS. VOL. 17. ISSUE 2. P. 215-222 16 50% 3
7 MAKRECKA, M , SVALBE, B , VOLSKA, K , SEVOSTJANOVS, E , LIEPINS, J , GRINBERGA, S , PUGOVICS, O , LIEPINSH, E , DAMBROVA, M , (2014) MILDRONATE, THE INHIBITOR OF L-CARNITINE TRANSPORT, INDUCES BRAIN MITOCHONDRIAL UNCOUPLING AND PROTECTS AGAINST ANOXIA-REOXYGENATION.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 723. ISSUE . P. 55-61 16 46% 5
8 AL TEMIMI, AHK , PIETERS, BJGE , REDDY, YV , WHITE, PB , MECINOVIC, J , (2016) SUBSTRATE SCOPE FOR TRIMETHYLLYSINE HYDROXYLASE CATALYSIS.CHEMICAL COMMUNICATIONS. VOL. 52. ISSUE 87. P. 12849 -12852 11 52% 1
9 LIEPINSH, E , MAKRECKA-KUKA, M , KUKA, J , VILSKERSTS, R , MAKAROVA, E , CIRULE, H , LOZA, E , LOLA, D , GRINBERGA, S , PUGOVICS, O , ET AL (2015) INHIBITION OF L-CARNITINE BIOSYNTHESIS AND TRANSPORT BY METHYL-GAMMA-BUTYROBETAINE DECREASES FATTY ACID OXIDATION AND PROTECTS AGAINST MYOCARDIAL INFARCTION.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 172. ISSUE 5. P. 1319 -1332 15 38% 3
10 GOGENS, C , GUDDAT, S , DIB, J , GEYER, H , SCHANZER, W , THEVIS, M , (2015) MILDRONATE (MELDONIUM) IN PROFESSIONAL SPORTS - MONITORING DOPING CONTROL URINE SAMPLES USING HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY - HIGH RESOLUTION/HIGH ACCURACY MASS SPECTROMETRY.DRUG TESTING AND ANALYSIS. VOL. 7. ISSUE 11-12. P. 973 -979 9 64% 1

Classes with closest relation at Level 1


Rank Class id link
1 973 CARNITINE//L CARNITINE//CARNITINE DEFICIENCY
2 12867 GLYCEROL OUTPUT//PALMITOYLCARNITINE//OXFENICINE
3 15395 TRIMETAZIDINE//PERHEXILINE//TRIMETAZIDINE MB
4 8921 CARNITINE PALMITOYLTRANSFERASE//CARNITINE PALMITOYLTRANSFERASE I//CARNITINE PALMITOYLTRANSFERASE DEFICIENCY
5 5486 CARDIAC METABOLISM//PROGRAM INTEGRAT CARDIAC METAB//HERITAGE MED 423
6 33842 AUTOREACTIVE LYMPHOCYTES T//COXSACKIEVIRUS A13//HUMAN ADENOVIRUS TYPE 6
7 29867 ADRENAL ARRHYTHMIA//AMBULATORY THER FUNCT DIAGNOST//ARTROFOON ENDOGENOUS INTOXICATION
8 18583 RANOLAZINE//LATE SODIUM CURRENT//LATE I NA
9 31577 PROLINE 3 HYDROXYLASE//PROLINE 4 HYDROXYLASE//ALPHA KETOGLUTARATE DEPENDENT IRONII OXYGENASES
10 12548 FLAVIN CONTAINING MONOOXYGENASE//FMO3//TRIMETHYLAMINURIA

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