Class information for:
Level 1: PEROXISOME PROLIFERATOR//PEROXISOME PROLIFERATION//3 THIA FATTY ACIDS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3761 1915 40.8 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
389 3       PEROXISOME//CARNITINE//JOURNAL OF INHERITED METABOLIC DISEASE 30841
1356 2             PEROXISOME//ADRENOLEUKODYSTROPHY//ZELLWEGER SYNDROME 8277
3761 1                   PEROXISOME PROLIFERATOR//PEROXISOME PROLIFERATION//3 THIA FATTY ACIDS 1915

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEROXISOME PROLIFERATOR authKW 1304433 9% 47% 174
2 PEROXISOME PROLIFERATION authKW 433987 3% 41% 66
3 3 THIA FATTY ACIDS authKW 287780 1% 95% 19
4 TETRADECYLTHIOACETIC ACID authKW 177207 1% 65% 17
5 CLOFIBRATE authKW 165095 3% 20% 52
6 CIPROFIBRATE authKW 161511 2% 35% 29
7 WY 14 643 authKW 161086 1% 42% 24
8 PEROXISOMAL BETA OXIDATION authKW 98901 1% 28% 22
9 NAFENOPIN authKW 96449 1% 55% 11
10 PPAR ALPHA authKW 88913 4% 8% 68

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 11923 24% 0% 458
2 Biochemistry & Molecular Biology 2624 33% 0% 632
3 Pharmacology & Pharmacy 2063 21% 0% 402
4 Biophysics 975 9% 0% 175
5 Oncology 923 13% 0% 253
6 Cell Biology 528 10% 0% 199
7 Medicine, Research & Experimental 269 6% 0% 107
8 Nutrition & Dietetics 211 3% 0% 65
9 Microscopy 85 1% 0% 16
10 Endocrinology & Metabolism 81 4% 0% 73

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLIN BIOCHEM 14321 HORINOUCHI 66430 0% 83% 5
2 LBBCM 47831 0% 100% 3
3 BIOL SCI MOLEC TOXICOL GRP 35872 0% 75% 3
4 PROTEOM GRP EST BIOL 31887 0% 100% 2
5 SECT FOOD HLTH 31887 0% 100% 2
6 UP 2402 31887 0% 100% 2
7 ZOOL ANIM ZELULEN DINAM SAILA 31887 0% 100% 2
8 BIOL ZELULARRA ETA HISTOL 28696 0% 60% 3
9 GDR CNRS 2583 28696 0% 60% 3
10 MICHAEL HOOKER 0031 25505 0% 40% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARCINOGENESIS 19043 6% 1% 118
2 BIOCHEMICAL PHARMACOLOGY 12106 6% 1% 119
3 TOXICOLOGY AND APPLIED PHARMACOLOGY 6566 3% 1% 64
4 ARCHIVES OF TOXICOLOGY 4695 2% 1% 36
5 PPAR RESEARCH 4681 1% 2% 12
6 FUNDAMENTAL AND APPLIED TOXICOLOGY 3956 1% 1% 23
7 LIPIDS 3075 2% 1% 34
8 TOXICOLOGY 2907 2% 1% 36
9 TOXICOLOGY LETTERS 2701 2% 0% 38
10 BIOCHIMICA ET BIOPHYSICA ACTA 2700 4% 0% 71

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PEROXISOME PROLIFERATOR 1304433 9% 47% 174 Search PEROXISOME+PROLIFERATOR Search PEROXISOME+PROLIFERATOR
2 PEROXISOME PROLIFERATION 433987 3% 41% 66 Search PEROXISOME+PROLIFERATION Search PEROXISOME+PROLIFERATION
3 3 THIA FATTY ACIDS 287780 1% 95% 19 Search 3+THIA+FATTY+ACIDS Search 3+THIA+FATTY+ACIDS
4 TETRADECYLTHIOACETIC ACID 177207 1% 65% 17 Search TETRADECYLTHIOACETIC+ACID Search TETRADECYLTHIOACETIC+ACID
5 CLOFIBRATE 165095 3% 20% 52 Search CLOFIBRATE Search CLOFIBRATE
6 CIPROFIBRATE 161511 2% 35% 29 Search CIPROFIBRATE Search CIPROFIBRATE
7 WY 14 643 161086 1% 42% 24 Search WY+14+643 Search WY+14+643
8 PEROXISOMAL BETA OXIDATION 98901 1% 28% 22 Search PEROXISOMAL+BETA+OXIDATION Search PEROXISOMAL+BETA+OXIDATION
9 NAFENOPIN 96449 1% 55% 11 Search NAFENOPIN Search NAFENOPIN
10 PPAR ALPHA 88913 4% 8% 68 Search PPAR+ALPHA Search PPAR+ALPHA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CORTON, JC , CUNNINGHAM, ML , HUMMER, BT , LAU, C , MEEK, B , PETERS, JM , POPP, JA , RHOMBERG, L , SEED, J , KLAUNIG, JE , (2014) MODE OF ACTION FRAMEWORK ANALYSIS FOR RECEPTOR-MEDIATED TOXICITY: THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR ALPHA) AS A CASE STUDY.CRITICAL REVIEWS IN TOXICOLOGY. VOL. 44. ISSUE 1. P. 1 -49 199 58% 24
2 KLAUNIG, JE , BABICH, MA , BAETCKE, KP , COOK, JC , CORTON, JC , DAVID, RM , DELUCA, JG , LAI, DY , MCKEE, RH , PETERS, JM , ET AL (2003) PPAR ALPHA AGONIST-INDUCED RODENT TUMORS: MODES OF ACTION AND HUMAN RELEVANCE.CRITICAL REVIEWS IN TOXICOLOGY. VOL. 33. ISSUE 6. P. 655 -780 187 42% 309
3 BENTLEY, P , CALDER, I , ELCOMBE, C , GRASSO, P , STRINGER, D , WIEGAND, HJ , (1993) HEPATIC PEROXISOME PROLIFERATION IN RODENTS AND ITS SIGNIFICANCE FOR HUMANS.FOOD AND CHEMICAL TOXICOLOGY. VOL. 31. ISSUE 11. P. 857-907 143 76% 217
4 O'BRIEN, ML , SPEAR, BT , GLAUERT, HP , (2005) ROLE OF OXIDATIVE STRESS IN PEROXISOME PROLIFERATOR-MEDIATED CARCINOGENESIS.CRITICAL REVIEWS IN TOXICOLOGY. VOL. 35. ISSUE 1. P. 61-88 133 49% 37
5 BECUWE, P , DAUCA, M , (2005) COMPARISON OF CYTOTOXICITY INDUCED BY HYPOLIPIDEMIC DRUGS VIA REACTIVE OXYGEN SPECIES IN HUMAN AND RODENT LIVER CELLS.INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. VOL. 16. ISSUE 3. P. 483-492 94 66% 5
6 LAKE, BG , (1995) MECHANISMS OF HEPATOCARCINOGENICITY OF PEROXISOME-PROLIFERATING DRUGS AND CHEMICALS.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 35. ISSUE . P. 483-507 90 78% 121
7 BOSGRA, S , MENNES, W , SEINEN, W , (2005) PROCEEDINGS IN UNCOVERING THE MECHANISM BEHIND PEROXISOME PROLIFERATOR-INDUCED HEPATOCARCINOGENESIS.TOXICOLOGY. VOL. 206. ISSUE 3. P. 309-323 73 79% 11
8 ASHBY, J , BRADY, A , ELCOMBE, CR , ELLIOTT, BM , ISHMAEL, J , ODUM, J , TUGWOOD, JD , KETTLE, S , PURCHASE, IFH , (1994) MECHANISTICALLY-BASED HUMAN HAZARD ASSESSMENT OF PEROXISOME PROLIFERATOR-INDUCED HEPATOCARCINOGENESIS.HUMAN & EXPERIMENTAL TOXICOLOGY. VOL. 13. ISSUE . P. S1-S117 120 49% 174
9 CATTLEY, RC , DELUCA, J , ELCOMBE, C , FENNER-CRISP, P , LAKE, BG , MARSMAN, DS , PASTOOR, TA , POPP, JA , ROBINSON, DE , SCHWETZ, B , ET AL (1998) DO PEROXISOME PROLIFERATING COMPOUNDS POSE A HEPATOCARCINOGENIC HAZARD TO HUMANS?.REGULATORY TOXICOLOGY AND PHARMACOLOGY. VOL. 27. ISSUE 1. P. 47 -60 59 81% 163
10 LOCK, EA , MITCHELL, AM , ELCOMBE, CR , (1989) BIOCHEMICAL-MECHANISMS OF INDUCTION OF HEPATIC PEROXISOME PROLIFERATION.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 29. ISSUE . P. 145 -163 67 77% 410

Classes with closest relation at Level 1


Rank Class id link
1 27804 ACYL COA THIOESTERASE//ACETYL COA HYDROLASE//ACYL COA HYDROLASE
2 3123 PPAR DELTA//PPAR BETA DELTA//PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR
3 5237 CARCINOGENESIS//MEDIUM TERM BIOASSAY//FOCI OF ALTERED HEPATOCYTES
4 1912 ADRENOLEUKODYSTROPHY//X LINKED ADRENOLEUKODYSTROPHY//PHYTANIC ACID
5 30827 DODECANEDIOIC ACID//DIETHYL SEBACATE//AZELAIC ACID
6 2721 PEROXISOME//PEROXIN//PEROXISOME BIOGENESIS
7 923 PHTHALATES//DEHP//DI2 ETHYLHEXYL PHTHALATE
8 9168 PPAR GAMMA//PPAR RESEARCH//TROGLITAZONE
9 14230 BETA KETOTHIOLASE DEFICIENCY//MITOCHONDRIAL ACETOACETYL COA THIOLASE//THIOLASE
10 10374 FENOFIBRATE//FENOFIBRIC ACID//FIBRATES

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