Class information for:
Level 1: ANTIESTROGEN//ANTIESTROGEN BINDING SITES//AEBS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5771 1577 38.5 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
159 3       MENOPAUSE//ISOFLAVONES//TAMOXIFEN 61134
329 2             TAMOXIFEN//ESTROGEN RECEPTOR//AROMATASE INHIBITORS 18133
5771 1                   ANTIESTROGEN//ANTIESTROGEN BINDING SITES//AEBS 1577

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTIESTROGEN authKW 206884 5% 14% 78
2 ANTIESTROGEN BINDING SITES authKW 154890 1% 100% 8
3 AEBS authKW 137678 1% 89% 8
4 DROLOXIFENE authKW 121618 1% 37% 17
5 EM 800 authKW 99570 0% 86% 6
6 TAMOXIFEN authKW 98500 9% 3% 148
7 CYCLOPROPYL ANTIESTROGENS authKW 77445 0% 100% 4
8 ANALOG II authKW 61954 0% 80% 4
9 DENDROGENIN authKW 61954 0% 80% 4
10 JC HEUSON CANCEROL MAMMAIRE address 61938 1% 27% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 8021 37% 0% 591
2 Endocrinology & Metabolism 6492 25% 0% 399
3 Biochemistry & Molecular Biology 968 24% 0% 377
4 Chemistry, Medicinal 494 6% 0% 94
5 Pharmacology & Pharmacy 460 12% 0% 195
6 Cell Biology 169 7% 0% 116
7 Biophysics 143 5% 0% 72
8 CYTOLOGY & HISTOLOGY 18 0% 0% 3
9 Obstetrics & Gynecology 11 2% 0% 26
10 Pathology 10 1% 0% 23

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JC HEUSON CANCEROL MAMMAIRE 61938 1% 27% 12
2 ALFRED G KNUDSON CHAIR CANC 60500 0% 63% 5
3 ENDOCRINOL CELLULAR COMMUN 38722 0% 100% 2
4 ENDOCRINOL METAB OSSEUX 38722 0% 100% 2
5 JC HEUSON CANC MAMMAIRE 38722 0% 100% 2
6 SERV HISTOL CYTOL EXPT 37227 0% 38% 5
7 EQUIPE METAB ONCOGENESE DIFFERENCIAT CELLULAIRE 29039 0% 50% 3
8 U148 UNITE ENDOCRINOL CELLULAIRE MOLEC 25814 0% 67% 2
9 TEAM STEROL METAB THER EUT INNOVAT ONCOL 24890 0% 43% 3
10 ANEXPLO US006 19361 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 58519 10% 2% 165
2 CANCER RESEARCH 9065 9% 0% 136
3 BREAST CANCER RESEARCH AND TREATMENT 7731 3% 1% 54
4 EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY 6911 2% 1% 26
5 ENDOCRINOLOGY 4074 5% 0% 73
6 MOLECULAR AND CELLULAR ENDOCRINOLOGY 3011 2% 0% 37
7 JOURNAL OF RECEPTOR RESEARCH 2682 1% 2% 9
8 BIOCHEMICAL PHARMACOLOGY 2444 3% 0% 49
9 ANTICANCER RESEARCH 1724 3% 0% 42
10 ENDOCRINE-RELATED CANCER 1665 1% 1% 12

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ANTIESTROGEN 206884 5% 14% 78 Search ANTIESTROGEN Search ANTIESTROGEN
2 ANTIESTROGEN BINDING SITES 154890 1% 100% 8 Search ANTIESTROGEN+BINDING+SITES Search ANTIESTROGEN+BINDING+SITES
3 AEBS 137678 1% 89% 8 Search AEBS Search AEBS
4 DROLOXIFENE 121618 1% 37% 17 Search DROLOXIFENE Search DROLOXIFENE
5 EM 800 99570 0% 86% 6 Search EM+800 Search EM+800
6 TAMOXIFEN 98500 9% 3% 148 Search TAMOXIFEN Search TAMOXIFEN
7 CYCLOPROPYL ANTIESTROGENS 77445 0% 100% 4 Search CYCLOPROPYL+ANTIESTROGENS Search CYCLOPROPYL+ANTIESTROGENS
8 ANALOG II 61954 0% 80% 4 Search ANALOG+II Search ANALOG+II
9 DENDROGENIN 61954 0% 80% 4 Search DENDROGENIN Search DENDROGENIN
10 ANTIESTROGEN DRUG 58084 0% 100% 3 Search ANTIESTROGEN+DRUG Search ANTIESTROGEN+DRUG

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 JORDAN, VC , (2015) THE NEW BIOLOGY OF ESTROGEN-INDUCED APOPTOSIS APPLIED TO TREAT AND PREVENT BREAST CANCER.ENDOCRINE-RELATED CANCER. VOL. 22. ISSUE 1. P. R1 -R31 76 51% 15
2 JORDAN, VC , MURPHY, CS , (1990) ENDOCRINE PHARMACOLOGY OF ANTIESTROGENS AS ANTITUMOR AGENTS.ENDOCRINE REVIEWS. VOL. 11. ISSUE 4. P. 578-610 140 46% 361
3 MACGREGOR, JI , JORDAN, VC , (1998) BASIC GUIDE TO THE MECHANISMS OF ANTIESTROGEN ACTION.PHARMACOLOGICAL REVIEWS. VOL. 50. ISSUE 2. P. 151 -196 118 27% 497
4 FAN, P , MAXIMOV, PY , CURPAN, RF , ABDERRAHMAN, B , JORDAN, VC , (2015) THE MOLECULAR, CELLULAR AND CLINICAL CONSEQUENCES OF TARGETING THE ESTROGEN RECEPTOR FOLLOWING ESTROGEN DEPRIVATION THERAPY.MOLECULAR AND CELLULAR ENDOCRINOLOGY. VOL. 418. ISSUE . P. 245 -263 73 39% 4
5 JORDAN, VC , (1984) BIOCHEMICAL PHARMACOLOGY OF ANTIESTROGEN ACTION.PHARMACOLOGICAL REVIEWS. VOL. 36. ISSUE 4. P. 245-276 83 64% 389
6 FAN, P , JORDAN, VC , (2014) ACQUIRED RESISTANCE TO SELECTIVE ESTROGEN RECEPTOR MODULATORS (SERMS) IN CLINICAL PRACTICE (TAMOXIFEN & RALOXIFENE) BY SELECTION PRESSURE IN BREAST CANCER CELL POPULATIONS.STEROIDS. VOL. 90. ISSUE . P. 44 -52 46 51% 4
7 PASQUALINI, JR , SUMIDA, C , GIAMBIAGI, N , (1988) PHARMACODYNAMIC AND BIOLOGICAL EFFECTS OF ANTI-ESTROGENS IN DIFFERENT MODELS.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 31. ISSUE 4B. P. 613-643 79 64% 76
8 JORDAN, VC , FAN, P , ABDERRAHMAN, B , MAXIMOV, PY , HAWSAWI, YM , BHATTACHARYA, P , POKHAREL, N , (2016) SEX STEROID INDUCED APOPTOSIS AS A RATIONAL STRATEGY TO TREAT ANTI-HORMONE RESISTANT BREAST AND PROSTATE CANCER.DISCOVERY MEDICINE. VOL. 21. ISSUE 117. P. 411 -427 42 48% 0
9 SILVENTE-POIROT, S , DE MEDINA, P , RECORD, M , POIROT, M , (2016) FROM TAMOXIFEN TO DENDROGENIN A: THE DISCOVERY OF A MAMMALIAN TUMOR SUPPRESSOR AND CHOLESTEROL METABOLITE.BIOCHIMIE. VOL. 130. ISSUE . P. 109 -114 28 67% 0
10 JORDAN, VC , (2015) PROVEN VALUE OF TRANSLATIONAL RESEARCH WITH APPROPRIATE ANIMAL MODELS TO ADVANCE BREAST CANCER TREATMENT AND SAVE LIVES: THE TAMOXIFEN TALE.BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 79. ISSUE 2. P. 254 -267 32 58% 0

Classes with closest relation at Level 1


Rank Class id link
1 6521 TAMOXIFEN//TOREMIFENE//ANTIESTROGEN
2 32633 THIOSENS//PHARMACOL CELLULAIRE MOL ANTICANC//ALPHANIZOMENON FLOS AQUAE
3 19527 ENDOXIFEN//TAMOXIFEN//N DESMETHYLTAMOXIFEN
4 7620 FULVESTRANT//ENDOCRINE RESISTANCE//FASLODEX
5 20988 LEHRSTUHL PHARMAZEUT CHEM 2//GRP RECH ONCOL ENDOCRINOL MOL//PORPHYRIN PLATINUM CONJUGATES
6 10644 ESTROGEN RECEPTOR//ESTROGEN RECEPTOR VARIANTS//TAMOXIFEN AZIRIDINE
7 25786 CENTCHROMAN//ORMELOXIFENE//TCCU
8 27208 SHIONOGI CARCINOMA 115//ESTROGEN SENSITIVE CELL LINE//CLIN EXPT PATHOPHYSIOL
9 35061 ESTROGENIC RECRUITMENT//2 P IODOPHENYL 3P NITROPHENYL 5 PHENYL TETRAZOLIUM CHLORIDE INT//CYCLODEXTRIN INDUCEMENT
10 12278 SERAM//MATH CHEM//RELATIVE BINDING AFFINITY

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