Class information for:
Level 2: TAMOXIFEN//ESTROGEN RECEPTOR//AROMATASE INHIBITORS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
329 18133 41.2 77%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
159 3       MENOPAUSE//ISOFLAVONES//TAMOXIFEN 61134
329 2             TAMOXIFEN//ESTROGEN RECEPTOR//AROMATASE INHIBITORS 18133
3946 1                   PROGESTERONE RECEPTOR//ESTROGEN RECEPTOR//ER ICA 1876
4960 1                   AROMATASE INHIBITORS//AROMATASE INHIBITOR//ANASTROZOLE 1696
5097 1                   AROMATASE INHIBITORS//ANASTROZOLE//EXEMESTANE 1673
5771 1                   ANTIESTROGEN//ANTIESTROGEN BINDING SITES//AEBS 1577
6521 1                   TAMOXIFEN//TOREMIFENE//ANTIESTROGEN 1474
6912 1                   ESTROGEN RECEPTOR BETA//ER BETA//RECEPTOR BIOL SECT 1430
7620 1                   FULVESTRANT//ENDOCRINE RESISTANCE//FASLODEX 1347
8689 1                   GPR30//GPER//G 1 1228
9000 1                   STEROID HORMONES SECT//AIB1//SRC 3 1198
10428 1                   BAZEDOXIFENE//RALOXIFENE//TISSUE SELECTIVE ESTROGEN COMPLEX 1065
10644 1                   ESTROGEN RECEPTOR//ESTROGEN RECEPTOR VARIANTS//TAMOXIFEN AZIRIDINE 1045
12278 1                   SERAM//MATH CHEM//RELATIVE BINDING AFFINITY 918
16550 1                   JIANGDA PATHOL//APOPTOTIC EFFECTS//BETA CX 648
19527 1                   ENDOXIFEN//TAMOXIFEN//N DESMETHYLTAMOXIFEN 501
24179 1                   ESTROGEN RECEPTOR 1//ESTROGEN RECEPTOR POLYMORPHISMS//ESR1 POLYMORPHISMS 321
32633 1                   THIOSENS//PHARMACOL CELLULAIRE MOL ANTICANC//ALPHANIZOMENON FLOS AQUAE 136

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 TAMOXIFEN authKW 1173263 10% 40% 1732
2 ESTROGEN RECEPTOR authKW 549149 8% 22% 1479
3 AROMATASE INHIBITORS authKW 534774 3% 58% 553
4 ANASTROZOLE authKW 265127 1% 62% 254
5 AROMATASE INHIBITOR authKW 252078 2% 45% 331
6 EXEMESTANE authKW 241247 1% 74% 195
7 ENDOCRINE THERAPY authKW 225441 2% 44% 305
8 BREAST CANCER authKW 214149 15% 5% 2669
9 FULVESTRANT authKW 211882 1% 72% 175
10 ESTROGEN RECEPTOR BETA authKW 173277 1% 40% 257

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 103595 40% 1% 7176
2 Endocrinology & Metabolism 32571 17% 1% 3116
3 Obstetrics & Gynecology 6538 6% 0% 1177
4 Biochemistry & Molecular Biology 4237 17% 0% 3058
5 Cell Biology 2860 8% 0% 1529
6 Chemistry, Medicinal 2064 4% 0% 712
7 Pathology 1409 3% 0% 580
8 Pharmacology & Pharmacy 1281 8% 0% 1380
9 Reproductive Biology 436 1% 0% 240
10 Medical Laboratory Technology 383 1% 0% 186

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STEROID HORMONES SECT 70066 0% 83% 50
2 JC HEUSON CANCEROL MAMMAIRE 33620 0% 67% 30
3 RECEPTOR BIOL SECT 23306 0% 33% 42
4 BREAST 22375 1% 11% 125
5 NUCL RECEPTORS CELL SIGNALING 21097 0% 22% 56
6 TUMOR ENDOCRINOL 20646 0% 47% 26
7 TENOVUS CANC 16588 0% 27% 36
8 BREAST ONCOL PROGRAM 15565 0% 31% 30
9 MIDLIFE HLTH 15126 0% 60% 15
10 LESTER SUE SMITH BREAST 14829 0% 18% 50

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BREAST CANCER RESEARCH AND TREATMENT 105803 4% 9% 677
2 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 93615 4% 8% 711
3 MOLECULAR ENDOCRINOLOGY 45195 2% 7% 391
4 ENDOCRINE-RELATED CANCER 22047 1% 9% 148
5 BREAST 21015 1% 7% 175
6 STEROIDS 14575 1% 5% 196
7 BREAST CANCER RESEARCH 13681 1% 6% 134
8 CLINICAL BREAST CANCER 12200 0% 10% 75
9 EUROPEAN JOURNAL OF CANCER 11597 1% 3% 267
10 EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY 11414 1% 6% 114

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 TAMOXIFEN 1173263 10% 40% 1732 Search TAMOXIFEN Search TAMOXIFEN
2 ESTROGEN RECEPTOR 549149 8% 22% 1479 Search ESTROGEN+RECEPTOR Search ESTROGEN+RECEPTOR
3 AROMATASE INHIBITORS 534774 3% 58% 553 Search AROMATASE+INHIBITORS Search AROMATASE+INHIBITORS
4 ANASTROZOLE 265127 1% 62% 254 Search ANASTROZOLE Search ANASTROZOLE
5 AROMATASE INHIBITOR 252078 2% 45% 331 Search AROMATASE+INHIBITOR Search AROMATASE+INHIBITOR
6 EXEMESTANE 241247 1% 74% 195 Search EXEMESTANE Search EXEMESTANE
7 ENDOCRINE THERAPY 225441 2% 44% 305 Search ENDOCRINE+THERAPY Search ENDOCRINE+THERAPY
8 BREAST CANCER 214149 15% 5% 2669 Search BREAST+CANCER Search BREAST+CANCER
9 FULVESTRANT 211882 1% 72% 175 Search FULVESTRANT Search FULVESTRANT
10 ESTROGEN RECEPTOR BETA 173277 1% 40% 257 Search ESTROGEN+RECEPTOR+BETA Search ESTROGEN+RECEPTOR+BETA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MACGREGOR, JI , JORDAN, VC , (1998) BASIC GUIDE TO THE MECHANISMS OF ANTIESTROGEN ACTION.PHARMACOLOGICAL REVIEWS. VOL. 50. ISSUE 2. P. 151 -196 358 81% 497
2 JORDAN, VC , (2003) ANTIESTROGENS AND SELECTIVE ESTROGEN RECEPTOR MODULATORS AS MULTIFUNCTIONAL MEDICINES. 2. CLINICAL CONSIDERATIONS AND NEW AGENTS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 46. ISSUE 7. P. 1081 -1111 302 81% 255
3 HERYNK, MH , FUQUA, SAW , (2004) ESTROGEN RECEPTOR MUTATIONS IN HUMAN DISEASE.ENDOCRINE REVIEWS. VOL. 25. ISSUE 6. P. 869-898 293 76% 204
4 PROSSNITZ, ER , ARTERBURN, JB , (2015) INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY. XCVII. G PROTEIN-COUPLED ESTROGEN RECEPTOR AND ITS PHARMACOLOGIC MODULATORS.PHARMACOLOGICAL REVIEWS. VOL. 67. ISSUE 3. P. 505 -540 241 60% 23
5 LE ROMANCER, M , POULARD, C , COHEN, P , SENTIS, S , RENOIR, JM , CORBO, L , (2011) CRACKING THE ESTROGEN RECEPTOR'S POSTTRANSLATIONAL CODE IN BREAST TUMORS.ENDOCRINE REVIEWS. VOL. 32. ISSUE 5. P. 597 -622 207 79% 76
6 ARIAZI, EA , ARIAZI, JL , CORDERA, F , JORDAN, VC , (2006) ESTROGEN RECEPTORS AS THERAPEUTIC TARGETS IN BREAST CANCER.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 6. ISSUE 3. P. 181 -202 187 90% 106
7 JORDAN, VC , (2003) ANTIESTROGENS AND SELECTIVE ESTROGEN RECEPTOR MODULATORS AS MULTIFUNCTIONAL MEDICINES. 1. RECEPTOR INTERACTIONS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 46. ISSUE 6. P. 883-908 208 76% 251
8 MUSA, MA , KHAN, MOF , COOPERWOOD, JS , (2007) MEDICINAL CHEMISTRY AND EMERGING STRATEGIES APPLIED TO THE DEVELOPMENT OF SELECTIVE ESTROGEN RECEPTOR MODULATORS (SERMS).CURRENT MEDICINAL CHEMISTRY. VOL. 14. ISSUE 11. P. 1249-1261 189 86% 34
9 FAN, P , MAXIMOV, PY , CURPAN, RF , ABDERRAHMAN, B , JORDAN, VC , (2015) THE MOLECULAR, CELLULAR AND CLINICAL CONSEQUENCES OF TARGETING THE ESTROGEN RECEPTOR FOLLOWING ESTROGEN DEPRIVATION THERAPY.MOLECULAR AND CELLULAR ENDOCRINOLOGY. VOL. 418. ISSUE . P. 245 -263 153 83% 4
10 MARTINKOVICH, S , SHAH, D , PLANEY, SL , ARNOTT, JA , (2014) SELECTIVE ESTROGEN RECEPTOR MODULATORS: TISSUE SPECIFICITY AND CLINICAL UTILITY.CLINICAL INTERVENTIONS IN AGING. VOL. 9. ISSUE . P. 1437 -1452 143 79% 23

Classes with closest relation at Level 2


Rank Class id link
1 1328 GLUCOCORTICOID RECEPTOR//ANTIPROGESTIN//JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
2 1407 2 METHOXYESTRADIOL//STEROID SULFATASE//17 BETA HYDROXYSTEROID DEHYDROGENASE
3 558 MENOPAUSE//HORMONE REPLACEMENT THERAPY//MATURITAS
4 652 HER2//TRASTUZUMAB//HER 2 NEU
5 994 BREAST CANCER//BREAST CONSERVING THERAPY//BREAST CONSERVING SURGERY
6 3251 NEUROENDOCRINOIMMUNOL//EXPT RHEUMATOL NEUROENDOCRINOIMMUNOL//EVANS IMMUNOL
7 3512 CENTCHROMAN//QUINONE METHIDE//O QUINONE METHIDE
8 2491 MAMMARY GLAND//JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA//MAMMARY STEM CELLS
9 2654 NURR1//NUR77//PGC 1 ALPHA
10 534 ANDROGEN RECEPTOR//PROSTATE CANCER//CASTRATION RESISTANT PROSTATE CANCER

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