Class information for:
Level 2: HER2//TRASTUZUMAB//HER 2 NEU

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
652 13568 43.0 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
652 2             HER2//TRASTUZUMAB//HER 2 NEU 13568
853 1                   TRIPLE NEGATIVE BREAST CANCER//TRIPLE NEGATIVE//ONCOTYPE DX 3005
2563 1                   TRASTUZUMAB//LAPATINIB//PERTUZUMAB 2207
4433 1                   NEUREGULIN//NEUREGULIN 1//ERBB4 1786
4440 1                   NIMOTUZUMAB//CETUXIMAB//EGFR 1785
5180 1                   C ERBB 2//HER 2 NEU//P185 1661
6321 1                   HER2//HER 2 NEU//TOP2A 1500
13462 1                   HER2//GASTRIC CANCER//HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 835
19156 1                   TISSUE MICROARRAY//MULTITISSUE BLOCK//PARAFFIN TISSUE CORE BIOPSIES 519
30546 1                   NUCLEAR EGFR//EGFR FAMILY RECEPTORS//P TYR 167
35026 1                   M1B PROSTATE CANCER//BIOMARKER EPIDERMAL GROWTH FACTOR RECEPTOR EGFR//C ERB B 2 NEU GENE 103

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 HER2 authKW 1119097 8% 44% 1143
2 TRASTUZUMAB authKW 1024617 7% 49% 925
3 HER 2 NEU authKW 357388 3% 35% 450
4 LAPATINIB authKW 339501 2% 51% 294
5 BREAST CANCER authKW 305213 20% 5% 2747
6 NEUREGULIN authKW 291915 2% 53% 245
7 NEUREGULIN 1 authKW 256512 1% 73% 157
8 HER 2 authKW 248345 2% 41% 272
9 ERBB2 authKW 219947 2% 31% 314
10 ERBB4 authKW 213785 1% 66% 144

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 178482 59% 1% 7978
2 Pathology 20964 12% 1% 1577
3 Cell Biology 3714 10% 0% 1406
4 Medical Laboratory Technology 2381 2% 0% 332
5 Obstetrics & Gynecology 1118 4% 0% 483
6 Medicine, Research & Experimental 829 4% 0% 560
7 Genetics & Heredity 586 4% 0% 574
8 Anatomy & Morphology 467 1% 0% 134
9 Biochemistry & Molecular Biology 407 10% 0% 1300
10 Pharmacology & Pharmacy 174 5% 0% 674

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 MED ONCOL 71038 9% 3% 1223
2 BREAST MED ONCOL 67413 2% 15% 204
3 PATHOL 51270 24% 1% 3212
4 ONCOL 35299 8% 2% 1072
5 ENDOCRINE CANC GRP 28396 0% 41% 31
6 JULES BORDET 26967 1% 12% 105
7 BREAKTHROUGH BREAST CANC 21579 1% 12% 82
8 RADIOBIOL MOL ENVIRONM 21214 0% 41% 23
9 BREAST CANC PROGRAM 20496 0% 14% 65
10 UNIT 1354 18673 0% 26% 32

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BREAST CANCER RESEARCH AND TREATMENT 68668 3% 7% 472
2 BREAST CANCER RESEARCH 39488 1% 9% 196
3 CLINICAL BREAST CANCER 32758 1% 14% 106
4 BREAST 22667 1% 7% 157
5 APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY 20895 1% 8% 118
6 CLINICAL CANCER RESEARCH 20885 3% 3% 376
7 ANNALS OF ONCOLOGY 19382 2% 3% 269
8 BREAST CARE 18660 1% 12% 69
9 ONCOLOGIST 17239 1% 6% 131
10 JOURNAL OF CLINICAL ONCOLOGY 17069 3% 2% 356

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 HER2 1119097 8% 44% 1143 Search HER2 Search HER2
2 TRASTUZUMAB 1024617 7% 49% 925 Search TRASTUZUMAB Search TRASTUZUMAB
3 HER 2 NEU 357388 3% 35% 450 Search HER+2+NEU Search HER+2+NEU
4 LAPATINIB 339501 2% 51% 294 Search LAPATINIB Search LAPATINIB
5 BREAST CANCER 305213 20% 5% 2747 Search BREAST+CANCER Search BREAST+CANCER
6 NEUREGULIN 291915 2% 53% 245 Search NEUREGULIN Search NEUREGULIN
7 NEUREGULIN 1 256512 1% 73% 157 Search NEUREGULIN+1 Search NEUREGULIN+1
8 HER 2 248345 2% 41% 272 Search HER+2 Search HER+2
9 ERBB2 219947 2% 31% 314 Search ERBB2 Search ERBB2
10 ERBB4 213785 1% 66% 144 Search ERBB4 Search ERBB4

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WOLFF, AC , HAMMOND, MEH , HICKS, DG , DOWSETT, M , MCSHANE, LM , ALLISON, KH , ALLRED, DC , BARTLETT, JMS , BILOUS, M , FITZGIBBONS, P , ET AL (2013) RECOMMENDATIONS FOR HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 TESTING IN BREAST CANCER: AMERICAN SOCIETY OF CLINICAL ONCOLOGY/COLLEGE OF AMERICAN PATHOLOGISTS CLINICAL PRACTICE GUIDELINE UPDATE.JOURNAL OF CLINICAL ONCOLOGY. VOL. 31. ISSUE 31. P. 3997-+ 121 90% 644
2 ROSS, JS , SLODKOWSKA, EA , SYMMANS, WF , PUSZTAI, L , RAVDIN, PM , HORTOBAGYI, GN , (2009) THE HER-2 RECEPTOR AND BREAST CANCER: TEN YEARS OF TARGETED ANTI-HER-2 THERAPY AND PERSONALIZED MEDICINE.ONCOLOGIST. VOL. 14. ISSUE 4. P. 320 -368 246 68% 414
3 WOLFF, AC , HAMMOND, MEH , HICKS, DG , DOWSETT, M , MCSHANE, LM , ALLISON, KH , ALLRED, DC , BARTLETT, JMS , BILOUS, M , FITZGIBBONS, P , ET AL (2014) RECOMMENDATIONS FOR HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 TESTING IN BREAST CANCER AMERICAN SOCIETY OF CLINICAL ONCOLOGY/COLLEGE OF AMERICAN PATHOLOGISTS CLINICAL PRACTICE GUIDELINE UPDATE.ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE. VOL. 138. ISSUE 2. P. 241 -256 122 90% 160
4 SANGUEDOLCE, F , BUFO, P , (2015) HER2 ASSESSMENT BY SILVER IN SITU HYBRIDIZATION: WHERE ARE WE NOW?.EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. VOL. 15. ISSUE 3. P. 385 -398 160 92% 0
5 MEI, L , NAVE, KA , (2014) NEUREGULIN-ERBB SIGNALING IN THE NERVOUS SYSTEM AND NEUROPSYCHIATRIC DISEASES.NEURON. VOL. 83. ISSUE 1. P. 27 -49 165 57% 65
6 HYNES, NE , STERN, DF , (1994) THE BIOLOGY OF ERBB-2 NEU HER-2 AND ITS ROLE IN CANCER.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1198. ISSUE 2-3. P. 165-184 175 72% 774
7 SITHANANDAM, G , ANDERSON, LM , (2008) THE ERBB3 RECEPTOR IN CANCER AND CANCER GENE THERAPY.CANCER GENE THERAPY. VOL. 15. ISSUE 7. P. 413 -448 229 54% 107
8 WOLFF, AC , HAMMOND, MEH , SCHWARTZ, JN , HAGERTY, KL , ALLRED, DC , COTE, RJ , DOWSETT, M , FITZGIBBONS, PL , HANNA, WM , LANGER, A , ET AL (2007) AMERICAN SOCIETY OF CLINICAL ONCOLOGY/COLLEGE OF AMERICAN PATHOLOGISTS GUIDELINE RECOMMENDATIONS FOR HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 TESTING IN BREAST CANCER.JOURNAL OF CLINICAL ONCOLOGY. VOL. 25. ISSUE 1. P. 118-145 56 90% 1843
9 MEI, L , XIONG, WC , (2008) NEUREGULIN 1 IN NEURAL DEVELOPMENT, SYNAPTIC PLASTICITY AND SCHIZOPHRENIA.NATURE REVIEWS NEUROSCIENCE. VOL. 9. ISSUE 6. P. 437 -452 127 65% 451
10 FURRER, D , SANSCHAGRIN, F , JACOB, S , DIORIO, C , (2015) ADVANTAGES AND DISADVANTAGES OF TECHNOLOGIES FOR HER2 TESTING IN BREAST CANCER SPECIMENS.AMERICAN JOURNAL OF CLINICAL PATHOLOGY. VOL. 144. ISSUE 5. P. 686 -703 138 91% 0

Classes with closest relation at Level 2


Rank Class id link
1 1648 EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA
2 1717 GEFITINIB//EGFR MUTATION//MIDKINE
3 994 BREAST CANCER//BREAST CONSERVING THERAPY//BREAST CONSERVING SURGERY
4 329 TAMOXIFEN//ESTROGEN RECEPTOR//AROMATASE INHIBITORS
5 2227 CARDIOTOXICITY//ANTHRACYCLINES//DOXORUBICIN
6 2606 FHIT//WWOX//FRAGILE SITES
7 2491 MAMMARY GLAND//JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA//MAMMARY STEM CELLS
8 1220 PTEN//MTOR//COWDEN SYNDROME
9 1071 LYNCH SYNDROME//MICROSATELLITE INSTABILITY//HNPCC
10 3290 HAND FOOT SYNDROME//HYPERSENSITIVITY REACTION//RADIATION RECALL

Go to start page