Class information for:
Level 1: TAMOXIFEN//TOREMIFENE//ANTIESTROGEN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6521 1474 36.0 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
159 3       MENOPAUSE//ISOFLAVONES//TAMOXIFEN 61134
329 2             TAMOXIFEN//ESTROGEN RECEPTOR//AROMATASE INHIBITORS 18133
6521 1                   TAMOXIFEN//TOREMIFENE//ANTIESTROGEN 1474

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TAMOXIFEN authKW 1501402 38% 13% 558
2 TOREMIFENE authKW 1230932 7% 57% 104
3 ANTIESTROGEN authKW 87318 3% 9% 49
4 GYNECOL ULTRASOUND UNIT address 84578 0% 58% 7
5 TAMOXIFEN ADVERSE EFFECTS authKW 82857 0% 100% 4
6 ENDOMETRIAL PATHOLOGY authKW 71207 1% 25% 14
7 ENDOMETRIAL SURVEILLANCE authKW 62143 0% 100% 3
8 ENDOMETRIAL POLYP authKW 41449 2% 8% 25
9 CANCBREAST CANC DIS PROGRAMDANA FARBER HARV address 41429 0% 100% 2
10 DEMOGRAPHIC AND REPRODUCTIVE CHARACTERISTICS authKW 41429 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 12503 48% 0% 703
2 Obstetrics & Gynecology 8553 23% 0% 345
3 Toxicology 635 7% 0% 102
4 Endocrinology & Metabolism 446 8% 0% 116
5 Pharmacology & Pharmacy 234 10% 0% 146
6 Reproductive Biology 179 3% 0% 37
7 Medicine, General & Internal 137 6% 0% 91
8 Pathology 114 3% 0% 47
9 Chemistry, Medicinal 71 3% 0% 42
10 Acoustics 23 1% 0% 16

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GYNECOL ULTRASOUND UNIT 84578 0% 58% 7
2 CANCBREAST CANC DIS PROGRAMDANA FARBER HARV 41429 0% 100% 2
3 ORION FARMOS 41429 0% 100% 2
4 AEGEAN OBSTET GYNECOL TEACHING HOSP 20714 0% 100% 1
5 ANALYSE STAT 20714 0% 100% 1
6 B T ONCOL 20714 0% 100% 1
7 BIOPATHOLSECT PATHOL ANAT 20714 0% 100% 1
8 BIOTECH CLINA SCI 20714 0% 100% 1
9 CANC COUNCIL CANC STUDIES 20714 0% 100% 1
10 CARCINOGENS DNA INTERACT SECT 20714 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 10732 3% 1% 39
2 BREAST CANCER RESEARCH AND TREATMENT 9894 4% 1% 59
3 CARCINOGENESIS 7704 4% 1% 66
4 GYNECOLOGIC ONCOLOGY 6059 4% 1% 58
5 EUROPEAN JOURNAL OF CANCER 4725 3% 0% 48
6 CHEMICAL RESEARCH IN TOXICOLOGY 4555 2% 1% 34
7 PROGRESS IN CLINICAL AND BIOLOGICAL RESEARCH 2296 0% 4% 3
8 INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 2019 1% 0% 21
9 INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY 1952 1% 1% 14
10 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 1758 2% 0% 28

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TAMOXIFEN 1501402 38% 13% 558 Search TAMOXIFEN Search TAMOXIFEN
2 TOREMIFENE 1230932 7% 57% 104 Search TOREMIFENE Search TOREMIFENE
3 ANTIESTROGEN 87318 3% 9% 49 Search ANTIESTROGEN Search ANTIESTROGEN
4 TAMOXIFEN ADVERSE EFFECTS 82857 0% 100% 4 Search TAMOXIFEN+ADVERSE+EFFECTS Search TAMOXIFEN+ADVERSE+EFFECTS
5 ENDOMETRIAL PATHOLOGY 71207 1% 25% 14 Search ENDOMETRIAL+PATHOLOGY Search ENDOMETRIAL+PATHOLOGY
6 ENDOMETRIAL SURVEILLANCE 62143 0% 100% 3 Search ENDOMETRIAL+SURVEILLANCE Search ENDOMETRIAL+SURVEILLANCE
7 ENDOMETRIAL POLYP 41449 2% 8% 25 Search ENDOMETRIAL+POLYP Search ENDOMETRIAL+POLYP
8 DEMOGRAPHIC AND REPRODUCTIVE CHARACTERISTICS 41429 0% 100% 2 Search DEMOGRAPHIC+AND+REPRODUCTIVE+CHARACTERISTICS Search DEMOGRAPHIC+AND+REPRODUCTIVE+CHARACTERISTICS
9 LEGITIMITY 41429 0% 100% 2 Search LEGITIMITY Search LEGITIMITY
10 POSTMENOPAUSAL TAMOXIFEN 41429 0% 100% 2 Search POSTMENOPAUSAL+TAMOXIFEN Search POSTMENOPAUSAL+TAMOXIFEN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BROWN, K , (2009) IS TAMOXIFEN A GENOTOXIC CARCINOGEN IN WOMEN?.MUTAGENESIS. VOL. 24. ISSUE 5. P. 391 -404 104 74% 20
2 COHEN, I , (2004) ENDOMETRIAL PATHOLOGIES ASSOCIATED WITH POSTMENOPAUSAL TAMOXIFEN TREATMENT.GYNECOLOGIC ONCOLOGY. VOL. 94. ISSUE 2. P. 256-266 80 93% 114
3 KIM, SY , SUZUKI, N , LAXMI, YRS , SHIBUTANI, S , (2004) GENOTOXIC MECHANISM OF TAMOXIFEN IN DEVELOPING ENDOMETRIAL CANCER.DRUG METABOLISM REVIEWS. VOL. 36. ISSUE 2. P. 199-218 79 84% 31
4 STEARNS, V , GELMANN, EP , (1998) DOES TAMOXIFEN CAUSE CANCER IN HUMANS?.JOURNAL OF CLINICAL ONCOLOGY. VOL. 16. ISSUE 2. P. 779 -792 94 82% 50
5 SMITH, LL , BROWN, K , CARTHEW, P , LIM, CK , MARTIN, EA , STYLES, J , WHITE, INH , (2000) CHEMOPREVENTION OF BREAST CANCER BY TAMOXIFEN: RISKS AND OPPORTUNITIES.CRITICAL REVIEWS IN TOXICOLOGY. VOL. 30. ISSUE 5. P. 571 -594 86 74% 37
6 DA COSTA, GG , PEREIRA, PC , CHURCHWELL, MI , BELAND, FA , MARQUES, MM , (2007) DNA ADDUCT FORMATION IN THE LIVERS OF FEMALE SPRAGUE-DAWLEY RATS TREATED WITH TOREMIFENE OR ALPHA-HYDROXYTOREMIFENE.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 20. ISSUE 2. P. 300 -310 63 80% 5
7 WHITE, INH , (2003) TAMOXIFEN: IS IT SAFE? COMPARISON OF ACTIVATION AND DETOXICATION MECHANISMS IN RODENTS AND IN HUMANS.CURRENT DRUG METABOLISM. VOL. 4. ISSUE 3. P. 223 -239 82 65% 39
8 KIM, SY , SUZUKI, N , LAXMI, YRS , MCGARRIGLE, BP , OLSON, JR , SHARMA, M , SHARMA, M , SHIBUTANI, S , (2005) FORMATION OF TAMOXIFEN-DNA ADDUCTS IN HUMAN ENDOMETRIAL EXPLANTS EXPOSED TO ALPHA-HYDROXYTAMOXIFEN.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 18. ISSUE 5. P. 889-895 54 92% 17
9 HARVEY, HA , KIMURA, M , HAJBA, A , (2006) TOREMIFENE: AN EVALUATION OF ITS SAFETY PROFILE.BREAST. VOL. 15. ISSUE 2. P. 142 -157 74 61% 36
10 DIBI, RP , ZETTLER, CG , PESSINI, SA , AYUB, AV , DE ALMEIDA, SB , DA SILVEIRA, GPG , (2009) TAMOXIFEN USE AND ENDOMETRIAL LESIONS: HYSTEROSCOPIC, HISTOLOGICAL, AND IMMUNOHISTOCHEMICAL FINDINGS IN POSTMENOPAUSAL WOMEN WITH BREAST CANCER.MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY. VOL. 16. ISSUE 2. P. 293-300 47 90% 11

Classes with closest relation at Level 1


Rank Class id link
1 10428 BAZEDOXIFENE//RALOXIFENE//TISSUE SELECTIVE ESTROGEN COMPLEX
2 19527 ENDOXIFEN//TAMOXIFEN//N DESMETHYLTAMOXIFEN
3 5771 ANTIESTROGEN//ANTIESTROGEN BINDING SITES//AEBS
4 4960 AROMATASE INHIBITORS//AROMATASE INHIBITOR//ANASTROZOLE
5 3567 ENDOMETRIAL POLYP//HYSTEROSCOPY//POSTMENOPAUSAL BLEEDING
6 23773 BIETTI CRYSTALLINE DYSTROPHY//CRYSTALLINE RETINOPATHY//CYP4V2
7 5097 AROMATASE INHIBITORS//ANASTROZOLE//EXEMESTANE
8 32633 THIOSENS//PHARMACOL CELLULAIRE MOL ANTICANC//ALPHANIZOMENON FLOS AQUAE
9 6394 UTERINE PAPILLARY SEROUS CARCINOMA//UTERINE SEROUS CARCINOMA//ENDOMETRIAL CARCINOMA
10 4558 HIGH DOSE CHEMOTHERAPY//DOSE INTENSITY//HIGH RISK BREAST CANCER

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