Class information for:
Level 1: CATECHOLESTROGENS//16 ALPHA HYDROXYESTRONE//ESTROGEN METABOLITES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5815 1571 36.9 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
159 3       MENOPAUSE//ISOFLAVONES//TAMOXIFEN 61134
1407 2             2 METHOXYESTRADIOL//STEROID SULFATASE//17 BETA HYDROXYSTEROID DEHYDROGENASE 8029
5815 1                   CATECHOLESTROGENS//16 ALPHA HYDROXYESTRONE//ESTROGEN METABOLITES 1571

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CATECHOLESTROGENS authKW 875813 5% 58% 78
2 16 ALPHA HYDROXYESTRONE authKW 236917 1% 76% 16
3 ESTROGEN METABOLITES authKW 236850 2% 42% 29
4 DEPURINATING ESTROGEN DNA ADDUCTS authKW 234609 1% 93% 13
5 ESTRADIOL METABOLISM authKW 198759 1% 68% 15
6 2 HYDROXYESTRONE authKW 193203 1% 76% 13
7 ESTROGEN METABOLISM authKW 188903 2% 28% 35
8 4 HYDROXYESTRADIOL authKW 146972 1% 69% 11
9 INDENESTROL A authKW 136046 0% 100% 7
10 CATECHOL ESTROGEN QUINONES authKW 116611 0% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 8880 29% 0% 462
2 Oncology 2974 24% 0% 374
3 Toxicology 2792 13% 0% 207
4 Biochemistry & Molecular Biology 1207 26% 0% 410
5 Chemistry, Medicinal 742 7% 0% 112
6 Pharmacology & Pharmacy 304 11% 0% 167
7 Chemistry, Multidisciplinary 80 8% 0% 123
8 Obstetrics & Gynecology 54 3% 0% 41
9 Public, Environmental & Occupational Health 44 4% 0% 57
10 Chemistry, Analytical 35 4% 0% 57

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MED CHEM PHARMACOGNOSY MC 781 112022 1% 41% 14
2 BIOCHEM CLIN ENDOCRINOL 77741 0% 100% 4
3 HLTH SCI MOVEMENT SCI 77741 0% 100% 4
4 EPPLEY CANC ALLIED DIS 62336 4% 6% 58
5 ETIOL PREVENT HORMONAL CANC 60731 0% 63% 5
6 LOS ANGELES CTY WOMENS HOSP 58306 0% 100% 3
7 KANSAS CANC HORMONAL CARCINOGENESIS 43728 0% 75% 3
8 KATSURAOKA CHO 71 43728 0% 75% 3
9 ENVIRONM AGR OCCUPAT HLTH 42446 1% 11% 20
10 MED CHEM PHARMACOGNOSY M C 781 38870 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 47232 9% 2% 148
2 STEROIDS 30069 5% 2% 82
3 CHEMICAL RESEARCH IN TOXICOLOGY 20400 5% 1% 74
4 CARCINOGENESIS 13794 6% 1% 91
5 HORMONES & CANCER 2152 0% 3% 4
6 CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 2046 2% 0% 26
7 ENDOCRINOLOGY 1452 3% 0% 44
8 ACTA ENDOCRINOLOGICA 1407 1% 0% 17
9 JOURNAL OF ENDOCRINOLOGY 1199 1% 0% 23
10 CANCER RESEARCH 1073 3% 0% 48

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CATECHOLESTROGENS 875813 5% 58% 78 Search CATECHOLESTROGENS Search CATECHOLESTROGENS
2 16 ALPHA HYDROXYESTRONE 236917 1% 76% 16 Search 16+ALPHA+HYDROXYESTRONE Search 16+ALPHA+HYDROXYESTRONE
3 ESTROGEN METABOLITES 236850 2% 42% 29 Search ESTROGEN+METABOLITES Search ESTROGEN+METABOLITES
4 DEPURINATING ESTROGEN DNA ADDUCTS 234609 1% 93% 13 Search DEPURINATING+ESTROGEN+DNA+ADDUCTS Search DEPURINATING+ESTROGEN+DNA+ADDUCTS
5 ESTRADIOL METABOLISM 198759 1% 68% 15 Search ESTRADIOL+METABOLISM Search ESTRADIOL+METABOLISM
6 2 HYDROXYESTRONE 193203 1% 76% 13 Search 2+HYDROXYESTRONE Search 2+HYDROXYESTRONE
7 ESTROGEN METABOLISM 188903 2% 28% 35 Search ESTROGEN+METABOLISM Search ESTROGEN+METABOLISM
8 4 HYDROXYESTRADIOL 146972 1% 69% 11 Search 4+HYDROXYESTRADIOL Search 4+HYDROXYESTRADIOL
9 INDENESTROL A 136046 0% 100% 7 Search INDENESTROL+A Search INDENESTROL+A
10 CATECHOL ESTROGEN QUINONES 116611 0% 100% 6 Search CATECHOL+ESTROGEN+QUINONES Search CATECHOL+ESTROGEN+QUINONES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LIEHR, JG , (2000) IS ESTRADIOL A GENOTOXIC MUTAGENIC CARCINOGEN?.ENDOCRINE REVIEWS. VOL. 21. ISSUE 1. P. 40 -54 89 62% 366
2 YAGER, JD , LIEHR, JG , (1996) MOLECULAR MECHANISMS OF ESTROGEN CARCINOGENESIS.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 36. ISSUE . P. 203 -232 95 55% 496
3 ZHU, BT , CONNEY, AH , (1998) FUNCTIONAL ROLE OF ESTROGEN METABOLISM IN TARGET CELLS: REVIEW AND PERSPECTIVES.CARCINOGENESIS. VOL. 19. ISSUE 1. P. 1 -27 106 35% 642
4 DALLAL, C , TAIOLI, E , (2010) URINARY 2/16 ESTROGEN METABOLITE RATIO LEVELS IN HEALTHY WOMEN: A REVIEW OF THE LITERATURE.MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. VOL. 705. ISSUE 2. P. 154-162 65 70% 3
5 BOLTON, JL , THATCHER, GRJ , (2008) POTENTIAL MECHANISMS OF ESTROGEN QUINONE CARCINOGENESIS.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 21. ISSUE 1. P. 93-101 65 58% 110
6 ROGAN, EG , CAVALIERI, EL , (2011) UNBALANCED METABOLISM OF ENDOGENOUS ESTROGENS IN THE ETIOLOGY AND PREVENTION OF HUMAN CANCER.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 125. ISSUE 3-5. P. 169 -180 53 66% 45
7 CAVALIERI, EL , ROGAN, EG , (2010) DEPURINATING ESTROGEN-DNA ADDUCTS IN THE ETIOLOGY AND PREVENTION OF BREAST AND OTHER HUMAN CANCERS.FUTURE ONCOLOGY. VOL. 6. ISSUE 1. P. 75 -91 53 68% 29
8 MARTUCCI, CP , FISHMAN, J , (1993) P450 ENZYMES OF ESTROGEN METABOLISM.PHARMACOLOGY & THERAPEUTICS. VOL. 57. ISSUE 2-3. P. 237-257 75 63% 309
9 SAEED, M , ROGAN, E , CAVALIERI, E , (2009) MECHANISM OF METABOLIC ACTIVATION AND DNA ADDUCT FORMATION BY THE HUMAN CARCINOGEN DIETHYLSTILBESTROL: THE DEFINING LINK TO NATURAL ESTROGENS.INTERNATIONAL JOURNAL OF CANCER. VOL. 124. ISSUE 6. P. 1276-1284 39 89% 15
10 ROY, D , LIEHR, JG , (1999) ESTROGEN, DNA DAMAGE AND MUTATIONS.MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. VOL. 424. ISSUE 1-2. P. 107 -115 45 85% 145

Classes with closest relation at Level 1


Rank Class id link
1 18998 2 METHOXYESTRADIOL//2 METHOXYOESTRADIOL//2 METHOXYESTRADIOL BIS SULPHAMATE
2 32486 HUMAN GENET TOXICOL SECT GENET//17 HYDROXY 3 OXOPREGNA 4 6 DIENE DERIVATIVES//ABERRANT METAPHASE NUMBER
3 14933 CYP1B1//CYP2S1//CYP2W1
4 17382 INDOLE 3 CARBINOL//3 3 DIINDOLYLMETHANE//DIINDOLYLMETHANE
5 22131 17 BETA DIHYDROEQUILIN//RING B UNSATURATED ESTROGENS//17 BETA DIHYDROEQUILIN SULFATE
6 32397 TYPE II H 3ESTRADIOL BINDING SITES//TYPE II SITES//GYNAECOL LARGO A GEMELLI 8
7 12490 DIETHYLSTILBESTROL//VAGINAL ADENOSIS//VAGINAL ADENOCARCINOMA
8 15938 GEORGE WHIPPLE CANC PATHOL//CHAWNSHANG CHANG LIVER CANC//ANAT STRUCT SCI
9 34154 C 13 NMR OF NAPHTHALENES//C 13 NMR SPECTRA OF ARENES//THIOGRISEOFULVIN
10 17026 FD LC MS MS METHOD//FLUOROGENIC DERIVATIZATION//DAABD CL

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