Class information for:
Level 1: ANGIOTENSIN CONVERTING ENZYME//ANGIOTENSIN I CONVERTING ENZYME//CD143

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8798 1215 32.7 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
85 2             ANGIOTENSIN II//RENIN ANGIOTENSIN SYSTEM//ANGIOTENSIN 27105
8798 1                   ANGIOTENSIN CONVERTING ENZYME//ANGIOTENSIN I CONVERTING ENZYME//CD143 1215

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANGIOTENSIN CONVERTING ENZYME authKW 352292 16% 7% 192
2 ANGIOTENSIN I CONVERTING ENZYME authKW 211247 5% 15% 58
3 CD143 authKW 157057 1% 63% 10
4 TESTICULAR ACE authKW 125652 0% 100% 5
5 DOMAIN SELECTIVITY authKW 75391 0% 100% 3
6 TESTIS ACE authKW 75391 0% 100% 3
7 KININASE II authKW 64968 1% 17% 15
8 ZINC METALLOPEPTIDASE authKW 64323 1% 32% 8
9 N DOMAIN authKW 58628 1% 33% 7
10 MEMBRANE FORM authKW 56542 0% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Andrology 3197 3% 0% 40
2 Biochemistry & Molecular Biology 2485 39% 0% 475
3 Peripheral Vascular Diseases 503 7% 0% 81
4 Medical Laboratory Technology 481 4% 0% 43
5 Pharmacology & Pharmacy 425 13% 0% 161
6 Biophysics 398 8% 0% 92
7 Physiology 260 6% 0% 73
8 Reproductive Biology 231 3% 0% 37
9 Medicine, Research & Experimental 192 6% 0% 71
10 Endocrinology & Metabolism 174 6% 0% 71

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ETUD INGN PROT 45232 0% 60% 3
2 INFECT DIS MOL MED 29253 4% 2% 48
3 ASSISTED REPROD FAMEZ 25130 0% 100% 1
4 BIOL PATHOPHYSIOL 25130 0% 100% 1
5 BRUCE R P ORT MED ANAT CELL BIOL 25130 0% 100% 1
6 BRUCE R P ORT MEDINTERNAL MED ELIPID 25130 0% 100% 1
7 CECOS SERV BIOL FERTIL CYTOGENET 25130 0% 100% 1
8 CLIN MED LIM 13 25130 0% 100% 1
9 CLIN MED LIM13 GENET CARDIOL MOL 25130 0% 100% 1
10 CLIN MEDLIM 13 25130 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANDROLOGIA 5949 2% 1% 26
2 ENDOTHELIUM-NEW YORK 1931 0% 8% 1
3 BIOCHEMISTRY-MOSCOW 1497 2% 0% 21
4 CLINICAL AND EXPERIMENTAL HYPERTENSION PART A-THEORY AND PRACTICE 1470 1% 1% 9
5 ENZYME & PROTEIN 1113 0% 2% 2
6 BIOLOGICAL CHEMISTRY 1111 1% 0% 12
7 HYPERTENSION 1024 2% 0% 22
8 TUMOR TARGETING 865 0% 3% 1
9 JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY 751 0% 1% 6
10 CLINICAL CHEMISTRY 738 2% 0% 19

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ANGIOTENSIN CONVERTING ENZYME 352292 16% 7% 192 Search ANGIOTENSIN+CONVERTING+ENZYME Search ANGIOTENSIN+CONVERTING+ENZYME
2 ANGIOTENSIN I CONVERTING ENZYME 211247 5% 15% 58 Search ANGIOTENSIN+I+CONVERTING+ENZYME Search ANGIOTENSIN+I+CONVERTING+ENZYME
3 CD143 157057 1% 63% 10 Search CD143 Search CD143
4 TESTICULAR ACE 125652 0% 100% 5 Search TESTICULAR+ACE Search TESTICULAR+ACE
5 DOMAIN SELECTIVITY 75391 0% 100% 3 Search DOMAIN+SELECTIVITY Search DOMAIN+SELECTIVITY
6 TESTIS ACE 75391 0% 100% 3 Search TESTIS+ACE Search TESTIS+ACE
7 KININASE II 64968 1% 17% 15 Search KININASE+II Search KININASE+II
8 ZINC METALLOPEPTIDASE 64323 1% 32% 8 Search ZINC+METALLOPEPTIDASE Search ZINC+METALLOPEPTIDASE
9 N DOMAIN 58628 1% 33% 7 Search N+DOMAIN Search N+DOMAIN
10 MEMBRANE FORM 56542 0% 75% 3 Search MEMBRANE+FORM Search MEMBRANE+FORM

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BERNSTEIN, KE , ONG, FS , BLACKWELL, WLB , SHAH, KH , GIANI, JF , GONZALEZ-VILLALOBOS, RA , SHEN, XZ , FUCHS, S , (2013) A MODERN UNDERSTANDING OF THE TRADITIONAL AND NONTRADITIONAL BIOLOGICAL FUNCTIONS OF ANGIOTENSIN-CONVERTING ENZYME.PHARMACOLOGICAL REVIEWS. VOL. 65. ISSUE 1. P. 1-46 138 33% 44
2 HARRISON, C , ACHARYA, KR , (2014) ACE FOR ALL - A MOLECULAR PERSPECTIVE.JOURNAL OF CELL COMMUNICATION AND SIGNALING. VOL. 8. ISSUE 3. P. 195 -210 57 78% 7
3 DANILOV, SM , GORDON, K , NESTEROVITCH, AB , LUNSDORF, H , CHEN, ZL , CASTELLON, M , POPOVA, IA , KALININ, S , MENDONCA, E , PETUKHOV, PA , ET AL (2011) AN ANGIOTENSIN I-CONVERTING ENZYME MUTATION (Y465D) CAUSES A DRAMATIC INCREASE IN BLOOD ACE VIA ACCELERATED ACE SHEDDING.PLOS ONE. VOL. 6. ISSUE 10. P. - 42 89% 4
4 NAPEROVA, IA , BALYASNIKOVA, IV , SCHWARTZ, DE , WATERMEYER, J , STURROCK, ED , KOST, OA , DANILOV, SM , (2008) MAPPING OF CONFORMATIONAL MAB EPITOPES TO THE C DOMAIN OF HUMAN ANGIOTENSIN I-CONVERTING ENZYME.JOURNAL OF PROTEOME RESEARCH. VOL. 7. ISSUE 8. P. 3396-3411 53 76% 4
5 DANILOV, SM , BALYASNIKOVA, IV , ALBRECHT, RF , KOST, OA , (2008) SIMULTANEOUS DETERMINATION OF ACE ACTIVITY WITH 2 SUBSTRATES PROVIDES INFORMATION ON THE STATUS OF SOMATIC ACE AND ALLOWS DETECTION OF INHIBITORS IN HUMAN BLOOD.JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. VOL. 52. ISSUE 1. P. 90-103 46 87% 3
6 MASUYER, G , YATES, CJ , STURROCK, ED , ACHARYA, KR , (2014) ANGIOTENSIN-I CONVERTING ENZYME (ACE): STRUCTURE, BIOLOGICAL ROLES, AND MOLECULAR BASIS FOR CHLORIDE ION DEPENDENCE.BIOLOGICAL CHEMISTRY. VOL. 395. ISSUE 10. P. 1135 -1149 58 55% 6
7 DANILOV, SM , LUNSDORF, H , AKINBI, HT , NESTEROVITCH, AB , EPSHTEIN, Y , LETSIOU, E , KRYUKOVA, OV , PIEGELER, T , GOLUKHOVA, EZ , SCHWARTZ, DE , ET AL (2016) LYSOZYME AND BILIRUBIN BIND TO ACE AND REGULATE ITS CONFORMATION AND SHEDDING.SCIENTIFIC REPORTS. VOL. 6. ISSUE . P. - 39 72% 0
8 KRYUKOVA, OV , TIKHOMIROVA, VE , GOLUKHOVA, EZ , EVDOKIMOV, VV , KALANTAROV, GF , TRAKHT, IN , SCHWARTZ, DE , DULL, RO , GUSAKOV, AV , UPOROV, IV , ET AL (2015) TISSUE SPECIFICITY OF HUMAN ANGIOTENSIN I-CONVERTING ENZYME.PLOS ONE. VOL. 10. ISSUE 11. P. - 36 77% 0
9 PETROV, MN , SHILO, VY , TARASOV, AV , SCHWARTZ, DE , GARCIA, JGN , KOST, OA , DANILOV, SM , (2012) CONFORMATIONAL CHANGES OF BLOOD ACE IN CHRONIC UREMIA.PLOS ONE. VOL. 7. ISSUE 11. P. - 45 65% 1
10 DANILOV, SM , KALININ, S , CHEN, ZL , VINOKOUR, EI , NESTEROVITCH, AB , SCHWARTZ, DE , GRIBOUVAL, O , GUBLER, MC , MINSHALL, RD , (2010) ANGIOTENSIN I-CONVERTING ENZYME GLN1069ARG MUTATION IMPAIRS TRAFFICKING TO THE CELL SURFACE RESULTING IN SELECTIVE DENATURATION OF THE C-DOMAIN.PLOS ONE. VOL. 5. ISSUE 5. P. - 44 69% 5

Classes with closest relation at Level 1


Rank Class id link
1 22028 ACSDKP//N ACETYL SERYL ASPARTYL LYSYL PROLINE//HEMOREGULATORY PEPTIDE
2 1245 CAS 89396 94 1//TA 6366//IMIDAPRIL
3 16038 LUNG METABOLIC FUNCTION//LUNG DRUG UPTAKE//PULMONARY CAPILLARY ENDOTHELIUM
4 29713 OCULAR RENIN ANGIOTENSIN SYSTEM//REN 2 RAT//S PHARMACOL MOL BIOL
5 10106 ANGIOTENSINOGEN//ADRENAL RENIN//HIGH MOLECULAR WEIGHT ANGIOTENSINOGEN
6 6313 ANGIOTENSIN 1 7//ANGIOTENSIN CONVERTING ENZYME 2//MAS RECEPTOR
7 25207 ANAPHYLACTROD REACTIONS//CRYPTOCOCCUS NEOFORMANS CYTOSKELETON//CYTOTOXICITY PERITONEAL MACROPHAGE
8 22358 THIMET OLIGOPEPTIDASE//NEUROLYSIN//ENDOPEPTIDASE 2415
9 5205 NEUTRAL ENDOPEPTIDASE//VASOPEPTIDASE INHIBITOR//OMAPATRILAT
10 1401 ANGIOTENSINOGEN//ANGIOTENSIN CONVERTING ENZYME//ANGIOTENSIN CONVERTING ENZYME GENE

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